퇴행성 신경질환 marker 항체 | 고마바이오텍

퇴행성 신경 질환 마커  

• 알츠하이머 : Amyloid beta, Amyloid Precursor Protein (APP), Presenilin-1 (PSEN 1, PS-1), Presenilin-2 (PSEN 2, PS-2), Tau protein 등   

• 파킨슨 :  alpha-synuclein (SNCA), Leucine rich repeat kinase 2 (LRRK 2), PTEN-induced putative kinase protein 1 (PINK 1), Parkin (PRKN) 등   

• 루게릭 병 (ALS/Amyotrophic Lateral Sclerosis) : chromosome 9 open reading frame 72(C9orf72 , ALSFTD), Superoxide dismutase (SOD1) 등    

• 헌팅턴 : Hungtingtin (HTT), Huntingtin-associated protein 1 (HAP1) 등

주요 제품

Anti-alpha Synuclein antibody (#ARG51249) 

• Product Description : Rabbit Polyclonal antibody recognizes alpha Synuclein
• Tested Reactivity : Hu, Ms, Rat
  
• Tested Application :  ICC/IF, WB
• Host : Rabbit
• Clonality : Polyclonal
• Isotype : IgG
• Target Name : alpha Synuclein
• Antigen Species : Human
• Immunogen : Peptide sequence around aa. 131~135 (E-G-Y-Q-D) derived from Human α-Synuclein.

 Anti-Huntingtin antibody [HDB4E10] (#ARG22448) 

• Product Description : Mouse Monoclonal antibody [HDB4E10] recognizes Huntingtin. This antibody recognizes with an epitope corresponding to the HDB region (amino acids 1844 - 2131) of the huntingtin protein. Mouse anti Huntingtin antibody, clone HDB4E10 detects a ~350 kDa band on western blots but also detects smaller degradation products of huntingtin. The combined use of Mouse anti Huntingtin antibody, clones HDB4E10, HDC8A4 and HDA3E10 demonstrate that huntingtin is enriched in neuronal cells in the brain (Jones 1999).
• Tested Reactivity : Hu, Ms, Rb
• Tested Application : IHC-Fr, IP, WB
• Host : Mouse
• Clonality : Monoclonal
• Clone : HDB4E10
• Isotype : IgG1
• Target Name : Huntingtin
• Antigen Species : Human
• Immunogen : Recombinant protein corresponding to amino acids 1844 - 2131 of huntingtin.

Anti-Presenilin 1 / PS1 (CTF) antibody (#ARG43010) 

• Product Description : Rabbit Polyclonal antibody recognizes Presenilin 1 / PS1 (CTF)
• Tested Reactivity : Hu, Ms, Rat
• Tested Application : WB
• Host : Rabbit
• Clonality : Polyclonal
• Isotype : IgG
• Target Name : Presenilin 1 / PS1 (CTF)
• Antigen Species : Human
• Immunogen : Synthetic peptide derived from Human Presenilin 1 / PS1 (C-terminal fragment).

Anti-Tau antibody (#ARG51094) 

• Product Description : Rabbit Polyclonal antibody recognizes Tau
• Tested Reactivity : Hu, Ms, Rat
• Tested Application : IHC-P, WB
• Host : Rabbit
• Clonality : Polyclonal
• Isotype : IgG
• Target Name : Tau
• Antigen Species : Human
• Immunogen : Peptide sequence around aa. 229~233 (V-R-T-P-P) derived from Human Tau.

Anti-Alpha-Synuclein Antibody (#APZ-035) 

• Type: Polyclonal
• Form: Lyophilized
• Applications: WB
• May also work in: ICC, IFC, IHC, IP
• Reactivity: M, R
• May also work in: H

Anti-Gamma-Synuclein Antibody (#APZ-037) 

• Host: Rabbit
• Type: Polyclonal
• Form: Lyophilized
• Applications: IF, IHC, WB
• May also work in: ICC, IP
• Reactivity: M, R