파킨슨병 연구 | Parkinson's Disease Small Molecules

Parkinson's Disease란?

Parkinson's disease (PD, 파킨슨병)은 종종 운동 능력, 언어 및 기타 기능을 손상시키는 중추신경계의 만성 퇴행성 질환입니다.
일반적으로 뇌의 도파민성 뉴런에서 생성되는 도파민의 형성 및 작용이 불충분하거나 소실로 인해 나타나며, 이는 루이(Lewy)소체의 침착과 함께 PD의 조직학적 특징입니다. 루이소체는 산화스트레스, 미토콘드리아 기능장애, 흥분성 및 염증을 유발합니다.
유전적 요인과 환경적 요인 모두 파킨슨 병의 발병 기전에 관여합니다. PD의 약리학적 치료는 도파민성 자극을 증가시키거나 콜린성 및 Glutamate성 자극을 억제하여 증상을 개선하는 것을 목표로 합니다.

주요 제품

Target	Cat. No.	Product
5-HT Transporters	4798	(S)-Duloxetine hydrochloride
5-HT Transporters	1588	Indatraline hydrochloride
5-HT1A Receptors	1080	(R)-(+)-8-Hydroxy-DPAT hydrobromide
	1060	(S)-(-)-Pindolol
	1253	(S)-WAY 100135 dihydrochloride
	0993	Cyanopindolol hemifumarate
	1869	Ipsapirone
	3282	NAD 299 hydrochloride
	0553	NAN-190 hydrobromide
	0912	RU 24969 hemisuccinate
	0631	Spiroxatrine
	3586	Sumatriptan succinate
	2854	Tandospirone hydrochloride
	4380	WAY 100635 maleate
5-HT1B Receptors	0703	Anpirtoline hydrochloride
	0638	CGS 12066B dimaleate
	1032	CP 93129 dihydrochloride
	1317	CP 94253 hydrochloride
	1054	GR 55562 dihydrochloride
	5136	Rizatriptan benzoate
	1242	SB 216641 hydrochloride
	1221	SB 224289 hydrochloride
	4657	Zolmitriptan
5-HT1D Receptors	1477	GR 127935 hydrochloride
5-HT2A Receptors	0523	4F 4PP oxalate
	1809	Altanserin hydrochloride
	4470	EMD 281014 hydrochloride
	0908	Ketanserin tartrate
	4173	MDL 100907
	0870	MDL 11,939
	1644	Mesulergine hydrochloride
	4493	Paliperidone
	1742	R-96544 hydrochloride
	2865	Risperidone
	3739	Sarpogrelate hydrochloride
	2592	TCB-2
5-HT2B Receptors	4081	LY 266097 hydrochloride
	3077	LY 272015 hydrochloride
	2993	RS 127445 hydrochloride
	1372	SB 204741
5-HT2C Receptors	1661	SB 206553 hydrochloride
5-HT2C Receptors	1375	SB 228357
5-HT7 Receptors	0529	8-Hydroxy-DPAT hydrobromide
5-HT-Related	3306	8-(3-Chlorostyryl)caffeine
Adenosine A2A Receptors	3937	ANR 94
	1063	CGS 21680 hydrochloride
	5147	Istradefylline
	4603	LUF 5834
	4334	PSB 0777 ammonium salt
	2463	SCH 442416
	2270	SCH 58261
	4407	TC-G 1004
	1036	ZM 241385
Adenosine A2B Receptors	1710	CV 1808
Adrenergic Related Compounds	0483	OR-486
Adrenergic Related Compounds	0724	Pirlindole mesylate
Adrenergic Transporters	1992	Nomifensine
AMPA Receptors	0169	(RS)-AMPA
	1074	(RS)-AMPA hydrobromide
	0254	(S)-AMPA
	1673	Cl-HIBO
	4373	CMPDA
	1045	CNQX disodium salt
	2932	CP 465022 hydrochloride
	2980	CX 546
	0713	Cyclothiazide
	0189	DNQX
	2312	DNQX disodium salt
	1454	GYKI 52466 dihydrochloride
	2555	GYKI 53655 hydrochloride
	1636	IEM 1460
	4198	IEM 1925 dihydrobromide
	2766	Naspm trihydrochloride
	0373	NBQX
	1044	NBQX disodium salt
	2770	Philanthotoxin 74
	5032	Talampanel
	2345	ZK 200775
Catechol O-Methyltransferase	4720	Entacapone
D1 and D5 Receptors	1534	A 68930 hydrochloride
	1249	CY 208-243
	0884	Dihydrexidine hydrochloride
	3548	Dopamine hydrochloride
	1659	Fenoldopam hydrochloride
	1674	LE 300
	0925	SCH 23390 hydrochloride
	2299	SCH 39166 hydrobromide
	0922	SKF 38393 hydrobromide
	1662	SKF 77434 hydrobromide
	1447	SKF 81297 hydrobromide
	1586	SKF 83566 hydrobromide
	2075	SKF 83822 hydrobromide
D2 Receptors	1003	L-741,626
	5041	PAOPA
	3896	Rotigotine hydrochloride
	2773	Sumanirole maleate
D3 Receptors	1243	(+)-PD 128907 hydrochloride
	3887	PG 01037 dihydrochloride
	4174	Pramipexole dihydrochloride
	4207	SB 277011A dihydrochloride
Dopamine Transporters	2831	Bupropion hydrochloride
	0513	GBR 12783 dihydrochloride
	0421	GBR 12909 dihydrochloride
	4351	JHW 007 hydrochloride
	2742	Reserpine
	2175	Tetrabenazine
GABAA Receptors	2503	(-)-Bicuculline methiodide
	0109	(-)-Bicuculline methobromide
	0131	(-)-Bicuculline methochloride
	0130	(+)-Bicuculline
	2681	17-PA
	3618	Acamprosate calcium
	3568	Bretazenil
	0456	Chlormezanone
	1709	CL 218872
	3083	DMCM hydrochloride
	3679	DS2
	3113	Etifoxine hydrochloride
	1471	Etomidate
	0554	FG 7142
	0658	FGIN-1-27
	1328	Flumazenil
	0344	GABA
	2531	Ganaxolone
	0235	Isoguvacine hydrochloride
	1327	L-655,708
	3250	L-838,417
	1295	Loreclezole hydrochloride
	4415	MK 0343
	3817	MRK 016
	0289	Muscimol
	4410	Ocinaplon
	2738	Org 20599
	1128	Picrotoxin
	1997	Ro 15-4513
	1512	SB 205384
	2143	SCS
	1262	SR 95531 hydrobromide
	0181	TACA
	2905	TB 21007
	4414	TP 003
	1558	Tracazolate hydrochloride
GABAB Receptors	0796	(R)-Baclofen
	0417	(RS)-Baclofen
	0245	2-Hydroxysaclofen
	1514	CGP 13501
	1245	CGP 35348
	3219	CGP 36216 hydrochloride
	1247	CGP 46381
	1246	CGP 52432
	1088	CGP 54626 hydrochloride
	1248	CGP 55845 hydrochloride
	1513	CGP 7930
	2001	GS 39783
	3313	rac BHFF
	4709	RuBi GABA trimethylphosphine
	3400	RuBi-GABA
	0246	Saclofen
	0984	SCH 50911
	0379	SKF 97541
GABAC Receptors	0807	THIP hydrochloride
GABAC Receptors	1040	TPMPA
Glutamate (Metabotropic) Group I Receptors	0187	(±)-trans-ACPD
	0342	(RS)-3,5-DHPG
	0336	(RS)-MCPG
	3696	(RS)-MCPG disodium salt
	0805	(S)-3,5-DHPG
	0323	(S)-4-Carboxyphenylglycine
	4416	ADX 10059 hydrochloride
	0904	AIDA
	2501	Bay 36-7620
	3235	CDPPB
	1049	CHPG
	3695	CHPG Sodium salt
	1028	CPCCOEt
	4787	CPPHA
	1625	DFB
	2386	Fenobam
	2333	JNJ 16259685
	0188	L-Quisqualic acid
	1237	LY 367385
	2390	LY 456236 hydrochloride
	1212	MPEP hydrochloride
	2921	MTEP hydrochloride
	4134	NPS 2390
	1027	PHCCC
	4347	Ro 67-4853
	4346	Ro 67-7476
	0162	S-Sulfo-L-cysteine sodium salt
	4323	VU 0360172 hydrochloride
	3413	YM 202074
Glutamate (Metabotropic) Group II Receptors	3272	(±)-LY 395756
	0284	(1S,3R)-ACPD
	1208	(2R,4R)-APDC
	0337	(S)-MCPG
	4048	BINA
	0975	DCG IV
	0333	L-CCG-l
	4969	LY 2389575 hydrochloride
	1209	LY 341495
	4062	LY 341495 disodium salt
	3246	LY 354740
	2453	LY 379268
	5064	LY 379268 disodium salt
	3283	LY 487379 hydrochloride
	4982	ML 337
	4388	MNI 137
	2913	Ro 64-5229
Glutamate (Metabotropic) Group III Receptors	1302	(S)-3,4-DCPG
	1111	ACPT-I
	2385	AMN 082 dihydrochloride
	0972	CPPG
	0103	L-AP4
	2963	MMPIP hydrochloride
	0803	MSOP
Glutamate Transporters	3697	7-Chlorokynurenic acid sodium salt
Glutamate Transporters	0845	Evans Blue tetrasodium salt
Histone Demethylases	4977	RN 1 dihydrochloride
Hydroxylases	3254	Ro 61-8048
Inward rectifier Potassium Channels	0964	Diazoxide
Kainate Receptors	0307	(S)-(-)-5-Iodowillardiine
	2728	ACET
	1107	ATPA
	0190	CNQX
	7065	Kainic acid (synthetic)
	3620	Topiramate
	2078	UBP 296
	1766	UBP 301
	2079	UBP 302
	3621	UBP 310
MEK	1777	Arctigenin
Miscellaneous GABA	2687	Pentylenetetrazole
Miscellaneous GABA	0808	Vigabatrin
Monoamine Oxidase	0767	Bifemelane hydrochloride
	2460	Lazabemide hydrochloride
	4395	Moclobemide
NKCC Cotransporter	3109	Furosemide
NMDA Receptors	0955	(-)-MK 801 maleate
	0924	(+)-MK 801 maleate
	0281	(R)-(+)-HA-966
	0247	(R)-CPP
	0312	(RS)-(Tetrazol-5-yl)glycine
	0173	(RS)-CPP
	0286	5,7-Dichlorokynurenic acid
	3698	5,7-Dichlorokynurenic acid sodium salt
	0237	7-Chlorokynurenic acid
	1469	CGP 37849
	1409	CGP 39551
	1493	CGP 78608 hydrochloride
	1241	CGS 19755
	4105	CIQ
	2456	Co 101244 hydrochloride
	0106	D-AP5
	1265	D-CPP-ene
	0105	DL-AP5
	3693	DL-AP5 Sodium salt
	4491	DQP 1105
	0226	D-Serine
	2195	Eliprodil
	2348	Gavestinel
	0219	Glycine
	3406	GLYX 13
	0742	L-689,560
	0705	L-701,252
	0907	L-701,324
	0107	L-AP5
	0773	Memantine hydrochloride
	2224	MNI-caged-NMDA
	0114	NMDA
	2530	PPDA
	4801	QNZ 46
	0225	Quinolinic acid
	1622	Remacemide hydrochloride
	2005	Ro 04-5595 hydrochloride
	1594	Ro 25-6981 maleate
	1250	SDZ 220-581
	0958	Spermine tetrahydrochloride
	4154	TCN 201
	4163	TCN 213
Non-selective 5-HT2	4349	Olanzapine
Non-selective 5-HT2	4735	Quetiapine hemifumarate
Non-selective Adrenergic Beta Receptors	2806	Alprenolol hydrochloride
Non-selective Dopamine	2073	(R)-(-)-Apomorphine hydrochloride
	0444	Clozapine
	4936	Clozapine N-oxide
	1847	Eticlopride hydrochloride
	1746	Nemonapride
Non-selective mGlu	0285	Ibotenic acid
Other Acetylcholine	2851	Nefiracetam
Other Channel Modulators	2625	Zonisamide
Oxytocin Receptors	4625	TC OT 39
Sigma2 Receptors	0545	Ifenprodil hemitartrate
Sigma2 Receptors	1497	Rimcazole dihydrochloride
Sigma-Related	2892	threo Ifenprodil hemitartrate
Stem Cell Dedifferentiation	3852	Tranylcypromine hydrochloride
Stem Cell Dedifferentiation	2815	Valproic acid, sodium salt
Voltage-gated Calcium Channels	0840	Loperamide hydrochloride
Voltage-Gated Potassium Channels	2867	Flupirtine maleate
Voltage-Gated Potassium Channels	4949	MaxiPost

주문정보

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
	Product	Cat.No.	Size	Maker	Qty	Data Sheet	MSDS

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파킨슨병 연구 | Parkinson's Disease Small Molecules | 고마바이오텍

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