고마바이오텍(주)
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제품 상세

Antibody

6.5 - 270 kDa 범위를 커버하는 3가지 컬러 밴드를 포함하며,
최대 100%까지의 transfer 효과를 개런티하는 Prestained protein ladder를 소개합니다.

배경

 

p53 은 전사 활성화, DNA 결합 및 올리고머화 도메인을 포함하는 종양 억제 단백질입니다.  
p53은 DNA 손상, oncogene 활성화, 산소 부족, 바이러스 감염 등 세포에 스트레스가 가해지면 활성화되어, G1/S기에서 세포를 멈추게 하여 성장을 막고 DNA 수선 단백질을 활성화하거나 손상을 복구할 수 없는 경우 세포 자살을 시작합니다.  

 

 

 

주요 제품

 

anti-p53 antibody [Pab1801] (#ARG10519)
Product Description Mouse Monoclonal antibody [Pab 1801] recognizes p53
Tested Reactivity Hu, Ms, Rat
Tested Application ChIP, ELISA, FACS, ICC/IF, IHC-Fr, IHC-P, IP, RIA, WB
Specificity The epitope of this antibody is located at aa 46-55 of the human p53 protein, so this antibody might react to both wild type and mutant form of p53 proteins.
Host Mouse
Clonality Monoclonal
Clone Pab 1801
Isotype IgG1
Target Name p53
Antigen Species Human
Immunogen Purified recombinant fragment within 32 to 79 aa of Human p53 protein (NP_000537.3).
Epitope Amino acids 46-55 of the human p53 protein
Conjugation Un-conjugated
Alternate Names TRP53; LFS1; Cellular tumor antigen p53; Phosphoprotein p53; Tumor suppressor p53; BCC7; Antigen NY-CO-13; P53
anti-p53 antibody [SQab1731] (#ARG66242)
Product Description Recombinant Rabbit Monoclonal antibody [SQab1731] recognizes p53
Tested Reactivity Hu
Tested Application IHC-P, WB
Host Rabbit
Clonality Monoclonal
Clone SQab1731
Isotype IgG
Target Name p53
Antigen Species Human
Immunogen Synthetic peptide around the N-terminus of Human p53.
Conjugation Un-conjugated
Alternate Names TRP53; LFS1; Cellular tumor antigen p53; Phosphoprotein p53; Tumor suppressor p53; BCC7; Antigen NY-CO-13; P53
anti-p53 antibody (#ARG59510)
Product Description Rabbit Polyclonal antibody recognizes p53
Tested Reactivity Hu
Predict Reactivity Rat
Tested Application ICC/IF, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name p53
Antigen Species Human
Immunogen Recombinant protein of Human p53.
Conjugation Un-conjugated
Alternate Names TRP53; LFS1; Cellular tumor antigen p53; Phosphoprotein p53; Tumor suppressor p53; BCC7; Antigen NY-CO-13; P53