고마바이오텍(주)
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제품 상세

Antibody

6.5 - 270 kDa 범위를 커버하는 3가지 컬러 밴드를 포함하며,
최대 100%까지의 transfer 효과를 개런티하는 Prestained protein ladder를 소개합니다.

 

  

  • 진핵세포에서 유전자 전사를 시작하거나 조절하는 데에 필요한 단백질입니다.
  • 일반적인 전사인자는 유전자의 기초 전사에 필요하며 전사 개시 복합체의 형성에 참여합니다.  
  • 대부분의 전사인자는 RNA 중합효소와 직접적으로 상호작용합니다.
  • 특정 전사인자는 개별 RNA 중합효소의 결합을 증진/차단하는 조정 조절 서열에 결합하는 것을 촉진하거나 차단하여 특정 유전자의 전사를 자극하거나 억제합니다.

 

  

주요 제품


     
AP-1      
       
  Cat. No. Product Name Activity
AP-1 Inhibitors 1989 c-JUN peptide JNK/c-Jun interaction inhibitor
5309 SP 100030 NF-κB and AP-1 dual inhibitor
2476 SR 11302 AP-1 inhibitor; antitumor agent
7317 T 5224 Selective inhibitor of c-Fos/activator protein (AP)-1
       
Aryl Hydrocarbon Receptor  
       
  Cat. No. Product Name Activity
Aryl Hydrocarbon Receptor Agonists 6321 10-Cl-BBQ Potent aryl hydrocarbon receptor (AhR) agonist; orally bioavailable
5304 FICZ High affinity aryl hydrocarbon receptor (AhR) agonist
1803 ITE Endogenous agonist for the transcription factor aryl hydrocarbon receptor
3873 MeBIO AhR agonist. Inactive analog of BIO (Cat. No. 3194)
1267 Pifithrin-α hydrobromide Aryl hydrocarbon receptor agonist. Also p53 inhibitor
Aryl Hydrocarbon Receptor Antagonists 3858 CH 223191 Potent aryl hydrocarbon receptor (AhR) antagonist
7086 StemRegenin 1 Aryl hydrocarbon receptor (AhR) antagonist; promotes HSC expansion and engraftment
Ligands 4393 L-Kynurenine Tryptophan catabolite; endogenous aryl hydrocarbon receptor ligand
Other 4995 Phortress Prodrug of the antitumor agent 5F 203
       
Hypoxia Inducible Factor  
       
  Cat. No. Product Name Activity
Hypoxia Inducible Factor (HIF) Inhibitors 5953 Adaptaquin HIF-prolyl hydroxylase-2 (PHD2) inhibitor; antioxidant
5582 TAT-cyclo-CLLFVY Selective HIF-1 dimerization inhibitor
4408 DMOG Inhibitor of hypoxia-inducible factor α (HIF-α) prolyl hydroxylase (HIF-PH)
5520 Echinomycin Highly potent and selective HIF-1α inhibitor
6653 FM19G11 HIF α-subunit inhibitor
5655 GN 44028 Potent HIF-1α inhibitor
4451 IOX 2 Potent, selective HIF-1α prolyl hydroxylase-2 (PHD2) inhibitor
4324 KC7F2 HIF-1α inhibitor; down-regulates HIF-1α protein synthesis
6322 LW 6 HIF-1α inhibitor; inhibits cellular accumulation of HIF-1α; also malate dehydrogenase-2 inhibitor
2954 PX 12 Thioredoxin-1 inhibitor; attenuates expression of HIF-1α
5243 TC-S 7009 High affinity and selective HIF-2α inhibitor
6156 VH 298 High-affinity inhibitor of VHL; blocks interaction of VHL and HIF-α
Hypoxia Inducible Factor (HIF) Activators 4565 ML 228 HIF pathway activator
Other 4705 Chetomin Blocks interaction of HIF-1α, HIF-2α and STAT2 with CBP/p300
6157 cis VH 298 Negative control for VH 298
5764 Deferoxamine mesylate Hypoxia mimetic; also iron chelator
7287 FAM-DEALA-Hyp-YIPD Fluorescent HIF-1α peptide
7452 FAM-DEALAHypYIPMDDDFQLRSF Fluorescent HIF-1α peptide
       
MYC      
       
  Cat. No. Product Name Activity
MYC Inhibitors 4406 10058-F4 Inhibits c-Myc-Max dimerization
5306 KJ Pyr 9 High affinity Myc inhibitor
       
NF-κB and IκB    
       
  Cat. No. Product Name Activity
NF-κB and IκB Inhibitors 4547 ACHP Selective IKKα and IKKβ inhibitor; blocks NF-κB-DNA binding
4857 Amlexanox Inhibitor of TBK1 and IKKε; antiallergic agent
1777 Arctigenin Inhibitor of IκBα phosphorylation. Also inhibits MEK1
1743 Bay 11-7085 Irreversible inhibitor of TNF-α-induced IκBα phosphorylation
1744 Bay 11-7821 Indirect inhibitor of IκBα phosphorylation
5273 Bengamide B Potent inhibitor of NF-κB activation
5300 BI 605906 Selective IKKβ inhibitor
4806 BMS 345541 Selective allosteric inhibitor of IKK; anti-inflammatory
5821 C-DIM 12 Inhibits NF-κB-dependent gene expression; Nurr1 activator
2743 Caffeic acid phenethyl ester Specific inhibitor of NF-κB activation
2509 Cardamonin Inhibitor of NF-κB activation; anti-inflammatory
6646 CDDO-Me NF-κB pathway inhibitor; inhibits IKKβ; also Nrf2 pathway activator
3203 Celastrol Inhibits TNF-α-induced NF-κB activation
6237 FPS ZM1 High affinity antagonist of the receptor for advanced glycation end products (RAGE)
2637 Gliotoxin Immunosuppressant; inhibits NF-κB and cytokine production
5672 GSK 319347A Potent and selective IKKε inhibitor
4590 Honokiol Blocks NF-κB activation; also anti-inflammatory and antioxidant
2539 IKK 16 Selective inhibitor of IKK
2611 IMD 0354 Inhibitor of IKKβ
5699 IP7e Blocks NF-κB pathway; also potent Nurr1 activator
5846 IT 901 NF-κB c-Rel subunit inhibitor
2874 Luteolin Blocks NF-κB activation
1748 MG 132 Inhibits NF-κB activation; proteasome and calpain inhibitor
4899 ML 120B dihydrochloride Novel IKK2-selective inhibitor
4354 ML 130 Inhibits NOD1-induced NF-κB activation
0610 Parthenolide NF-κB inhibitor; also 5-HT release inhibitor
4238 PF 184 Potent and selective IKKβ inhibitor
1554 Piceatannol Inhibits TNF-induced NF-κB activation
1947 PR 39 (porcine) IκBα inhibitor
3731 Pristimerin Suppresses NF-κB activation
4569 PS 1145 dihydrochloride Selective IKK inhibitor; orally active
0727 Pyrrolidinedithiocarbamate ammonium Inhibits NF-κB, prevents increase in NOS mRNA
6259 RAGE antagonist peptide Receptor for advanced glycation end products (RAGE) antagonist
3318 SC 514 IKKβ inhibitor; attenuates NF-κB-induced gene expression
6829 (R)-Shikonin Blocks TNF-α and NF-κB signaling; induces necroptosis; anti-inflammatory
5309 SP 100030 NF-κB and AP-1 dual inhibitor
4935 Sulfasalazine Inhibitor of NF-κB activation; also inhibits SXC and folate transporter 1
4426 Tanshinone IIA Inhibits NF-κB and AP-1 DNA binding. Displays antioxidant properties
2559 TPCA-1 Potent, selective inhibitor of IKKβ
2816 Withaferin A Inhibits NF-κB activation
6111 Zoledronic Acid NF-κB signaling inhibitor; also potent farnesyl diphosphate (FPP) synthase inhibitor
NF-κB and IκB Activators 3906 Betulinic acid Activates NF-κB; antitumor and anti-HIV agent. Also TGR5 agonist
6124 (R)-2-Hydroxyglutaric acid disodium salt NF-κB activator; also KDM4A inhibitor
5739 Prostratin NF-κB activator; also PKC activator
Other 1126 Dexamethasone Reduces levels of activated NF-κB in immature dendritic cells; anti-inflammatory glucocorticoid
       
NFAT      
       
  Cat. No. Product Name Activity
NFAT Inhibitors 3930 NFAT Inhibitor Inhibitor of calcineurin-mediated NFAT activation
5710 NFAT inhibitor, Cell Permeable Cell permeable NFAT inhibitor
Other 4210 Ascomycin Calcineurin phosphatase inhibitor; analog of FK 506 (Cat. No. 3631)
1101 Cyclosporin A Calcineurin inhibitor
3631 FK 506 Potent calcineurin inhibitor; immunosuppressant
2162 INCA-6 Inhibitor of calcineurin-NFAT association
       
Nrf2      
       
  Cat. No. Product Name Activity
Nrf2 Inhibitors 6243 ML 385 Nrf2 inhibitor; phenotypically lethal
Nrf2 Activators 5145 AI-3 ARE activator; induces Nrf2-ARE-dependent transcription
4737 CDDO Im Nrf2 signaling activator
6646 CDDO-Me Nrf2 pathway activator; also NF-κB pathway inhibitor; inhibits IKKβ
4512 DMF Activator of Nrf2 pathway; neuroprotective
7199 (±)-Eriodictyol Activates Nrf2/ARE signaling; antioxidant; also potent TRPV1 antagonist
6172 INF 4E Activates Keap1-Nrf2 pathway; also caspase-1 and NLRP3 inflammasome inhibitor
5625 ML 334 Inhibitor of Keap1- Nrf2 interaction
4511 MMF Activator of Nrf2 pathway; primary metabolite of DMF (Cat. No. 4512)
5293 NK 252 Nrf2 activator
6662 4-Octyl itaconate Nrf2 activator; cell permeable
5294 Oltipraz Nrf2 activator
5707 RA 839 Nrf2 activator; inhibits Nrf2/Keap1 interaction
4811 TAT 14 Nrf2 pathway activator; blocks Nrf2/Keap1 interaction
       
p53      
       
  Cat. No. Product Name Activity
p53 Inhibitors 1267 Pifithrin-α hydrobromide p53 inhibitor. Also aryl hydrocarbon receptor agonist
3843 Cyclic Pifithrin-α hydrobromide p53 inhibitor
2653 Pifithrin-μ Inhibitor of p53-mitochondrial binding
p53 Activators 3503 HLI 373 Hdm2 inhibitor; activates p53-dependent transcription
6904 Idasanutlin Potent MDM2 inhibitor; inhibits MDM2-p53 interaction
6615 KCC 07 BAI1/p53 signaling activator; inhibits MBD2 (Methyl-CpG-binding domain protein 2)
2185 NSC 146109 hydrochloride Cell-permeable, genotype-selective antitumor agent; activates p53-dependent transcription
5065 NSC 319726 Reactivator of mutant p53
3984 Nutlin-3 MDM2 antagonist; inhibits MDM2-p53 interaction
6075 Nutlin 3a MDM2 antagonist; active enantiomer of Nutlin-3 (Cat. No. 3984)
2443 RITA p53-MDM2 interaction inhibitor; antitumor
5332 SP 141 High affinity MDM2 inhibitor
3365 Tenovin-1 Activates p53 transcriptional activity
3356 WR 1065 dihydrochloride p53 activator. Also ROS scavenger
Other 5417 BMH 21 p53 pathway activator; also RNA polymerase 1 inhibitor
3362 MIRA-1 Restores mutant p53 activity; proapoptotic
4326 PhiKan 083 p53 stabilizing agent
4396 Piperlongumine Induces apoptosis; increases p53 and ROS levels in cancer cells
1862 PRIMA-1 Restores mutant p53 activity; induces apoptosis
3710 PRIMA-1MET Restores mutant p53 activity
3214 RETRA hydrochloride Antitumor agent; suppresses mutant p53-bearing cancer cells
4240 SCH 529074 Restores mutant p53 activity
       
SREBP      
       
  Cat. No. Product Name Activity
SREBP Inhibitors 4444 Fatostatin A Cell permeable inhibitor of SREBP activation
3354 PF 429242 dihydrochloride Competitive inhibitor of SREBP site 1 protease
       
STAT      
       
  Cat. No. Product Name Activity
STAT Inhibitors 1571 Cucurbitacin I Selective inhibitor of STAT3/JAK2 signaling
6218 Galiellalactone STAT3 inhibitor; active in vivo
6110 HJC 0416 hydrochloride STAT3 inhibitor
5522 Napabucasin STAT3 inhibitor; also blocks cancer stem cell self-renewal
4079 Niclosamide STAT3 inhibitor; also inhibits mTORC1 signaling
4655 NSC 74859 Selective STAT3 inhibitor
3918 Pyrimethamine STAT3 inhibitor; also potent inhibitor of multidrug and toxin extrusion (MATE) transporters and DHFR inhibitor
5138 RSVA 405 STAT3 inhibitor; also AMPK activator
3035 SD 1008 JAK2/STAT3 signaling pathway inhibitor
2798 Stattic Selective STAT3 inhibitor
STAT Activators 3945 Colivelin STAT3 activator; also protects against β-amyloid neurotoxicity
Other 3495 Fludarabine Purine analog; inhibits cytokine-induced STAT1 activation
6994 HODHBt STAT5-SUMO protein-protein interaction inhibitor


주문정보

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS
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제품 문의

0.5 ml Elite Pre-stained Protein Ladder (2 x 0.25 ml) PAL-EPL-500 0.5ml 500
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