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제품 상세

Antibody

6.5 - 270 kDa 범위를 커버하는 3가지 컬러 밴드를 포함하며,
최대 100%까지의 transfer 효과를 개런티하는 Prestained protein ladder를 소개합니다.

프린트 제품 문의

배 경

  

  • GABA Receptor는 중추신경계의 주요 억제성 신경전달물질인 GABA에 반응하는 수용체 군으로, GABA A와 GABA B 두가지 그룹이 있습니다. 
  • GABA A Receptor는 이온성 수용체 (ionotropic receptor)로 ligand-gated channel 이라고도 하며 Cl-의 개폐를 조정하고, GABA B Receptor는 대사성 수용체 (metabotropic receptor)로, K+ 채널의 개폐를 조정합니다. 



GABAA Receptor 주요 제품 

　 GABAA Receptor Agonists 　
　 Cat. No. Product Name Activity
　 0344 GABA Endogenous agonist
　 0235 Isoguvacine hydrochloride Selective GABAA agonist
　 3250 L-838,417 GABAA partial agonist; displays subtype selectivity
　 4415 MK 0343 GABAA partial agonist; displays subtype selectivity
　 0289 Muscimol Potent GABAA agonist; also GABAA-ρ partial agonist
　 4709 RuBi GABA trimethylphosphine Caged GABA; inhibits neural activity
　 0181 TACA GABAA agonist; also GABA-T substrate and GABA uptake inhibitor
　 0807 THIP hydrochloride GABAA agonist
　 　 　 　
　 GABAA Receptor Inverse Agonists 　
　 Cat. No. Product Name Activity
　 3817 MRK 016 α5-selective GABAA inverse agonist
　 2905 TB 21007 α5-selective GABAA inverse agonist
　 　 　 　
　 GABAA Receptor Antagonists 　
　 Cat. No. Product Name Activity
　 2503 (-)-Bicuculline methiodide GABAA antagonist; more water soluble version of (+)-bicuculline (Cat. No. 0130)
　 0109 (-)-Bicuculline methobromide GABAA antagonist; more water soluble version of (+)-bicuculline (Cat. No. 0130)
　 0131 (-)-Bicuculline methochloride GABAA antagonist; more water soluble version of (+)-bicuculline (Cat. No. 0130)
　 0130 (+)-Bicuculline Potent GABAA antagonist
　 3109 Furosemide GABAA antagonist; also Na+/2Cl-/K+ cotransporter blocker
　 4466 PHP 501 trifluoroacetate Potent GABAA antagonist
　 1128 Picrotoxin GABAA antagonist
　 2143 SCS Potent GABAA antagonist; β1-subunit selective
　 1262 SR 95531 hydrobromide Competitive and selective GABAA antagonist
　 　 　 　
　 Benzodiazepines 　
　 Cat. No. Product Name Activity
　 3568 Bretazenil Benzodiazepine partial agonist
　 0456 Chlormezanone Positive allosteric modulator of benzodiazepine site
　 1709 CL 218872 Benzodiazepine agonist
　 2805 Diazepam Acts at the benzodiazepine modulatory site
　 3083 DMCM hydrochloride Benzodiazepine inverse agonist
　 0554 FG 7142 Benzodiazepine inverse agonist
　 0658 FGIN-1-27 Potent ligand for mitochondrial DBI receptor; GABAA receptor modulator
　 1328 Flumazenil Benzodiazepine antagonist
　 1327 L-655,708 Benzodiazepine inverse agonist; selective for α5-containing GABAA receptors
　 2832 Midazolam hydrochloride Benzodiazepine agonist
　 1997 Ro 15-4513 Benzodiazepine partial inverse agonist
　 4414 TP 003 GABAA partial agonist; acts at benzodiazepine site
　 0405 β-CCB Benzodiazepine inverse agonist; putative endogenous ligand
　 　 　 　
GABAA Receptor Modulators
　 Cat. No. Product Name Activity
　 2681 17-PA Antagonist of neurosteroid potentiation and direct gating of GABAA
　 3972 AA 29504 Positive allosteric modulator of GABAA receptors
　 3653 Allopregnanolone Positive allosteric modulator of GABAA receptors
　 3679 DS2 Positive allosteric modulator of GABAA receptors; displays subunit selectivity
　 3113 Etifoxine hydrochloride GABAA potentiator; anxiolytic
　 1471 Etomidate GABA-mimetic; selectively interacts with β2- and β3-subunit containing GABAA receptors
　 2867 Flupirtine maleate GABAA modulator; also indirect NMDA antagonist and Kv7 channel activator
　 2531 Ganaxolone Potent positive allosteric modulator of GABAA receptors
　 1295 Loreclezole hydrochloride Subtype-selective GABAA modulator
　 4949 MaxiPost Negative modulator of GABAA receptors; also potassium channel modulator
　 4410 Ocinaplon GABAA modulator; anxiolytic
　 2738 Org 20599 Positive allosteric modulator of GABAA receptors; direct agonist at higher concentrations
　 3652 Pregnanolone Postitive allosteric modulator of GABAA receptors
　 5376 Pregnenolone sulfate sodium salt GABAA inhibitor; displays some subunit selectivity; NMDA potentiator; also activates TRPM3 channels
　 6192 PZ-II-029 α6β3γ2-selective GABAA positive allosteric modulator
　 1512 SB 205384 GABAA modulator; slows current decay
　 6334 THDOC Positive modulator of GABAA receptors; endogenous neurosteroid
　 3620 Topiramate Positive allosteric modulator of GABAA receptors; GluK1 antagonist; also inhibits carbonic anhydrase (CA) II and IV
　 1558 Tracazolate hydrochloride Allosteric modulator of GABAA receptors
　 2734 U 89843A Positive allosteric modulator of GABAA receptors




GABAB Receptors 주요 제품

GABAB Receptor Agonists
　 Cat. No. Product Name Activity
　 0796 (R)-Baclofen Selective GABAB agonist; active enantiomer of (RS)-Baclofen (Cat. No. 0417)
　 0417 (RS)-Baclofen Selective GABAB agonist
　 0344 GABA Endogenous agonist
　 4709 RuBi GABA trimethylphosphine Caged GABA; inhibits neural activity
　 3400 RuBi-GABA Caged GABA; excitable at visible wavelengths
　 0379 SKF 97541 Highly potent GABAB agonist; also GABAA-ρ antagonist
　 　 　 　
　 GABAB Receptor Antagonists 　
　 Cat. No. Product Name Activity
　 0245 2-Hydroxysaclofen Selective GABAB antagonist; more potent than Saclofen (Cat. No. 0246)
　 1245 CGP 35348 Selective GABAB antagonist; brain penetrant
　 3219 CGP 36216 hydrochloride GABAB antagonist; displays activity at presynaptic receptors
　 1247 CGP 46381 Selective GABAB antagonist; brain penetrant
　 1246 CGP 52432 Potent and selective GABAB antagonist
　 1088 CGP 54626 hydrochloride Potent and selective GABAB antagonist
　 1248 CGP 55845 hydrochloride Potent and selective GABAB antagonist
　 0246 Saclofen Selective GABAB antagonist
　 0984 SCH 50911 Selective and competitive GABAB antagonist; orally bioavailable
　 　 　 　
　 GABAB Receptor Modulators 　
　 Cat. No. Product Name Activity
　 1514 CGP 13501 Positive allosteric modulator of GABAB receptors
　 1513 CGP 7930 Positive allosteric modulator of GABAB receptors
　 2001 GS 39783 Positive allosteric modulator of GABAB receptors
　 3313 rac BHFF Potent and selective postitive allosteric modulator of GABAB receptors
　 　
　 Other 　 　
　 Cat. No. Product Name Activity
　 0386 3-Methyl-GABA Activator of GABA amino-transferase
　 1811 Modafinil Psychostimulant
　 4579 Pentobarbital sodium salt Enhances GABAergic activity
　 2687 Pentylenetetrazole CNS stimulant
　 2815 Valproic acid, sodium salt Increases GABA levels; anticonvulsant
　 2625 Zonisamide Modulates GABA neurotransmission; anticonvulsant


 





주문정보

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관련제품

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자료

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제품 문의

 0.5 ml Elite Pre-stained Protein Ladder (2 x 0.25 ml) PAL-EPL-500 0.5ml 500
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