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제품 상세
세포 독성 측정 | Cytotoxicity Assay 이미지

세포 독성 측정 | Cytotoxicity Assay

CytoSelect™ LDH Cytotoxicity Assay Kit, EnzyLight™ Cytotoxicity Assay Kit등 세포 생존력, 증식력, 세포 독성 측정 및 항암제 스크리닝을 위한 assay kit을 소개합니다.

프린트 제품 문의

CytoSelect™ LDH Cytotoxicity Assay Kit (#CBA-241) 

 

  • 세포 독성 측정 및 모니터링을 위한 kit 입니다.
  • 세포에 화합물을 처리하여 죽으면 유리되는 LDH (Lactate dehydrogenase)는 lactate를 pyruvate로 전환시키면서 NADH를 생성하고 이는 WST-1을 orange formazan form으로 전환하여 컬러 반응을 일으킵니다. 
  • adherent, non-adherent 세포에 모두 적용됩니다.





EnzyLight™ Cytotoxicity Assay Kit (#ECTX-100)

  • 세포 생존력, 증식력, 세포 독성 측정 및 항암제 스크리닝을 위한 luciferin/luciferase 기반의 분석 킷트 입니다. 
  • cell이 lysis되어 세포내 ATP가 유리되면 luciferase와 반응하여 D-luciferin으로부터 light을 생성합니다. 


사용 논문

CBA-241 　
    1. Haba, D. et al. (2021). Low-frequency vibration promotes AMPK-mediated glucose uptake in 3T3-L1 adipocytes. Heliyon. 7(9):e07897. doi: 10.1016/j.heliyon.2021.e07897.
    2. Torrisi, F. et al. (2021). Connexin 43 and Sonic Hedgehog Pathway Interplay in Glioblastoma Cell Proliferation and Migration. Biology (Basel). 10(8):767. doi: 10.3390/biology10080767.
    3. Dziwornu, G.A. et al. (2021). Antimalarial Benzimidazole Derivatives Incorporating Phenolic Mannich Base Side Chains Inhibit Microtubule and Hemozoin Formation: Structure-Activity Relationship and In Vivo Oral Efficacy Studies. J Med Chem. doi: 10.1021/acs.jmedchem.1c00354.
    4. Tang, Y. et al. (2021). Repurposing a Cardiovascular Disease Drug of Cloridarol as hIAPP Inhibitor. ACS Chem Neurosci. doi: 10.1021/acschemneuro.1c00091.
    5. Pardo-Mora, D.P. et al. (2021). Apoptosis-related gene expression induced by Colombian propolis samples in canine osteosarcoma cell line. Vet World. 14(4): 964-971. doi: 10.14202/vetworld.2021.964-971.
    6. Aydemir Sezer, U. et al. (2020). Zero Valent Iron Nanoparticles Containing Nanofiber Scaffolds for Nerve Tissue Engineering. J Tissue Eng Regen Med. doi: 10.1002/term.3137.
    7. Probst, A. et al. (2020). Expanding the activity profile of pyrido[1,2-a]benzimidazoles: Synthesis and evaluation of novel N1-1-phenylethanamine derivatives against Schistosoma mansoni. ACS Infect Dis. doi: 10.1021/acsinfecdis.0c00278.
    8. Shun, Q.T. et al. (2020). Naja sumatrana venom cytotoxin, sumaCTX exhibits concentration-dependent cytotoxicity via caspase-activated mitochondrial-mediated apoptosis without transitioning to necrosis. Toxin Rev. doi: 10.1080/15569543.2020.1799408.
    9. Casanova-Martí, À. et al. (2020). Long Term Exposure to a Grape Seed Proanthocyanidin Extract Enhances L-Cell Differentiation in Intestinal Organoids. Mol Nutr Food Res. doi: 10.1002/mnfr.202000303.
    10. Fabijańska, M. et al. (2020). Simple Trans-Platinum Complex Bearing 3-Aminoflavone Ligand Could Be a Useful Drug: Structure-Activity Relationship of Platinum Complex in Comparison with Cisplatin. Int. J. Mol. Sci. 21:2116. doi: 10.3390/ijms21062116.
    11. Pires, S. et al. (2020). Biological sex influences susceptibility to Acinetobacter baumannii pneumonia in mice. JCI Insight. pii: 132223. doi: 10.1172/jci.insight.132223.
    12. Mavangira, V. et al. (2020). 20-hydroxyeicosatetraenoic acid alters endothelial cell barrier integrity independent of oxidative stress and cell death. Prostaglandins Other Lipid Mediat. doi: 10.1016/j.prostaglandins.2020.106425.
    13. Pagoni, A. et al. (2019). Novel anti-Alzheimer phenol-lipoyl hybrids: Synthesis, physico-chemical characterization, and biological evaluation. Eur J Med Chem. doi: 10.1016/j.ejmech.2019.111880.
    14. Vicario, N. et al. (2019). Simultaneous Activation of Mu and Delta Opioid Receptors Reduces Allodynia and Astrocytic Connexin 43 in an Animal Model of Neuropathic Pain. Mol Neurobiol. doi: 10.1007/s12035-019-1607-1.
    15. Bahmani Jalali, H. et al. (2018). Effective Neural Photostimulation Using Indium-Based Type-II Quantum Dots. ACS Nano. 12(8):8104-8114. doi: 10.1021/acsnano.8b02976.
    16. van Krüchten, A. et al. (2018). Staphylococcus aureus triggers a shift from influenza virus-induced apoptosis to necrotic cell death. FASEB J. 32(5):2779-2793. doi: 10.1096/fj.201701006R.
    17. Geyikoglu, F. et al. (2017). Toxicological evaluation of submerged liquid culture from Phanerochaete chrysosporium mycelium on human blood cells: cytotoxicity, genotoxicity and oxidative damage. International Journal of Secondary Metabolite. 4(2017):319-329. doi: 10.21448/ijsm.373809.
    18. Bengtsson, T. et al. (2017). Dual action of bacteriocin PLNC8 αβ through inhibition of Porphyromonas gingivalis infection and promotion of cell proliferation. Pathog. Dis. doi: 10.1093/femspd/ftx064.
    19. Chu, J. et al. (2015). Pharmacologic blockade of 12/15-lipoxygenase ameliorates memory deficits, Aβ and tau neuropathology in the triple-transgenic mice.Mol Psychiatry. 20(11):1329-38. doi: 10.1038/mp.2014.170.
    20. Chu, J. et al. (2015). Gamma secretase-activating protein is a substrate for caspase-3: implications for Alzheimer’s disease.  Biol Psychiatry. 77:720-728. doi: 10.1016/j.biopsych.2014.06.003.
    21. Li, J. G. et al. (2014). Homocysteine exacerbates β-amyloid pathology, tau pathology, and cognitive deficit in a mouse model of Alzheimer disease with plaques and tangles. Ann Neurol. 75:851-863.


주문정보

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS
CytoSelect™ LDH Cytotoxicity Assay Kit CBA-241 960 assays CELL BIOLABS
EnzyLight™ Cytotoxicity Assay Kit ECTX-100 100 assays BIOASSAY SYSTEMS
Genorise® LDH Cytotoxicity Assay Kit GR107034 1000 tests GENORISE
LDH Cytotoxicity Assay Kit ARG81306 960 assay ARIGO
QuantiChrom™ LDH Cytotoxicity Assay Kit C2LD-100 100 assays BIOASSAY SYSTEMS
Maker
CELL BIOLABS
Cat.No.
CBA-241
Product
CytoSelect™ LDH Cytotoxicity Assay Kit
Size
960 assays
Qty
Data Sheet
MSDS
Maker
BIOASSAY SYSTEMS
Cat.No.
ECTX-100
Product
EnzyLight™ Cytotoxicity Assay Kit
Size
100 assays
Qty
Data Sheet
MSDS
Maker
GENORISE
Cat.No.
GR107034
Product
Genorise® LDH Cytotoxicity Assay Kit
Size
1000 tests
Qty
Maker
ARIGO
Cat.No.
ARG81306
Product
LDH Cytotoxicity Assay Kit
Size
960 assay
Qty
Data Sheet
Maker
BIOASSAY SYSTEMS
Cat.No.
C2LD-100
Product
QuantiChrom™ LDH Cytotoxicity Assay Kit
Size
100 assays
Qty
Data Sheet
MSDS

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주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS

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