|
Coronavirus |
|
|
Cat. No. |
Product
Name |
Activity |
|
4274 |
AP 24534 |
Identified as
targeting human proteins in the SARS-CoV-2 interactome |
|
7283 |
Apilimod
dimesylate |
Inhibits
cellular entry by SARS-CoV-2, MERS-CoV and MHV S pseudovirions |
|
7235 |
Arbidol |
Inhibits
replication of SARS-CoV-2 in vitro; broad spectrum antiviral |
|
4600 |
Auranofin |
Inhibits
SARS-CoV-2 infection in vitro |
|
3771 |
Azithromycin |
Predicted
to disrupt binding of SARS-CoV-2 spike protein to ACE2 |
|
7222 |
Baricitinib |
In
silico modelling predicts inhibition of SARS-CoV-2
cell entry; highly potent JAK inhibitor |
|
3193 |
Camostat
mesylate |
Inhibits
entry of SARS-Cov-2 into lung cells; TMPRSS2 inhibitor |
|
4109 |
Chloroquine
diphosphate |
Inhibits
SARS-CoV-2 infection in vitro |
|
6357 |
Ciclesonide |
Inhibits
replication of SARS-CoV-2 in vitro; glucocorticoid |
|
0460 |
Cinanserin
hydrochloride |
Inhibits
replication of SARS-CoV; Mpro inhibitor and 5-HT2 antagonist |
|
0970 |
Cycloheximide |
Exhibits
anti-MERS-CoV activity in vitro; protein synthesis inhibitor |
|
1101 |
Cyclosporin
A |
Inhibits
coronavirus replication; cyclophilin inhibitor |
|
7223 |
Dabrafenib
mesylate |
Targets
human proteins in the SARS-CoV-2 interactome |
|
1467 |
Daunorubicin
hydrochloride |
Identified
as targeting human proteins in the SARS-CoV-2 interactome |
|
4583 |
Digoxin |
Exhibits
anti-MERS-CoV activity in vitro; Na+/K+ ATPase inhibitor |
|
7336 |
Dinaciclib |
Exhibits
antiviral activity against SARS-CoV-2 in vitro |
|
3807 |
Disulfiram |
SARS-CoV-2
Mpro inhibitor; also reversibly stimulates SERCA Ca2+-ATPase |
|
4545 |
E 64d |
Inhibts
entry of SARS-CoV-2 into lung cells in combination
with Camostat (Cat. No. 3193) |
|
5245 |
Ebselen |
Inhibits
SARS-CoV-2 Mpro in vitro;
glutathione peroxidase mimic |
|
6986 |
EG
00229 trifluoroacetate |
Inhibits
binding of cleaved spike protein of SARS-CoV-2 to neuropilin 1 (NRP1) |
|
7231 |
EIDD 1931 |
Inhibits
MERS-CoV and SARS-CoV-2 replication in vitro |
|
7225 |
Favipiravir |
Reduces
infection rate of SARS-CoV-2 in vitro; viral RNA polymerase inhibitor |
|
3631 |
FK 506 |
Identified
as targeting human proteins in the SARS-CoV-2 interactome |
|
7229 |
Galidesivir
dihydrochloride |
Broad
spectrum antiviral nucleotide; inhibits coronavirus replication in vitro |
|
3259 |
Gemcitabine
hydrochloride |
Inhibits
replication of coronaviruses; DNA synthesis inhibitor |
|
7280 |
GRL 0617 |
Coronavirus
PLpro inhibitor |
|
7227 |
GS 441524 |
Displays
antiviral activity against MERS-CoV, SARS-CoV and SARS-CoV-2 |
|
1416 |
Homoharringtonine |
Inhibits
SARS-CoV-2 infection in vitro; inhibits protein synthesis |
|
5648 |
Hydroxychloroquine
sulfate |
Inhibits
SARS-CoV-2 viral infection in vitro |
|
5906 |
Imatinib
mesylate |
Inhibits
replication of SARS-CoV and MERS-CoV in vitro |
|
1708 |
Indomethacin |
Identified
as targeting human proteins in the SARS-CoV-2 interactome |
|
1260 |
Ivermectin |
Inhibits
replication of SARS-Cov-2 in vitro; antiparasitic and antiviral |
|
2959 |
Lercanidipine
hydrochloride |
Exhibits
anti-MERS-CoV activity in vitro; CaV1.x blocker |
|
3765 |
Linezolid |
Identified
as targeting human proteins in the SARS-CoV-2 interactome; antibiotic |
|
0840 |
Loperamide
hydrochloride |
Inhibits
replication of coronaviruses in vitro |
|
7052 |
Lopinavir |
Inhibits
SARS-CoV-2 replication in vitro; highly potent and selective HIV-1 protease inhibitor |
|
6819 |
Mefloquine
hydrochloride |
Exhibits
antiviral activities against SARS-CoV-2; also Cx36 and Cx50 gap channel
blocker |
|
2864 |
Metformin
hydrochloride |
Identified
as targeting human proteins in the SARS-CoV-2 interactome; antidiabetic |
|
7228 |
MPro 13b |
Coronavirus
Mpro inhibitor |
|
7230 |
MPro N3 |
Coronavirus
Mpro inhibitor |
|
3081 |
Nafamostat
mesylate |
Inhibits
SARS-CoV-2 infection in vitro; serine protease inhibitor |
|
3766 |
Nelfinavir
mesylate |
Exhibits
anti-MERS-CoV activity in vitro; potent HIV-1 protease inhibitor |
|
4079 |
Niclosamide |
Inhibits
SARS-CoV-2 spike protein induced syncytia formation and viral
replication in vitro |
|
7234 |
Nitazoxanide |
Inhibits
SARS-CoV-2 infection in vitro |
|
2583 |
Omeprazole |
Enhances
anti-SARS-CoV-2 activity of serine protease inhibitors |
|
1076 |
Ouabain |
Exhibits
anti-MERS-CoV activity in vitro; Na+/K+ ATPase inhibitor |
|
7357 |
PLpro
inhibitor 6 |
SARS-CoV
and SARS-CoV-2 PLpro inhibitor |
|
1125 |
Quercetin |
Inhibits
SARS-CoV Mpro; also non-selective PI 3-kinase inhibitor |
|
1292 |
Rapamycin |
Inhibits
MERS-CoV infection; mTOR inhibitor and immunosuppressant |
|
7226 |
Remdesivir |
Displays
antiviral activity against MERS-CoV, SARS-CoV and SARS-CoV-2 |
|
4501 |
Ribavirin |
Inhibits
cytopathic effect of SARS-CoV in vitro; guanosine analog and IMPDH inhibitor |
|
5856 |
Ritonavir |
Improves
outcome in an animal model of MERS-CoV infection; HIV protease inhibitor |
|
7064 |
Ruxolitinib |
Targets
human proteins in the SARS-CoV-2 interactome; potent and selective JAK1/JAK2
inhibitor |
|
7191 |
Santacruzamate
A |
Identified
as targeting human host proteins that interact with SARS-CoV-2 |
|
7189 |
Saracatinib |
Inhibits
MERS-CoV, other coronaviruses and dengue virus |
|
7192 |
SMIP 004 |
S-phase
kinase-associated protein 2 (SKP2) inhibitor |
|
1138 |
Thapsigargin |
Inhibits
SARS-CoV-2 infection in vitro; SERCA inhibitor |
|
2815 |
Valproic
acid, sodium salt |
Identified
as targeting human proteins in the SARS-CoV-2 interactome; HDAC inhibitor |
|
0654 |
Verapamil
hydrochloride |
Targets
human proteins in the SARS-CoV-2 interactome; CaV1.x blocker |
|
|
|
|
|
Herpes Simplex Viruses |
|
|
Cat. No. |
Product
Name |
Activity |
|
2513 |
Acyclovir |
Antiviral
agent; active against herpes simplex viruses |
|
6244 |
OG-L002 |
Inhibits
herpes simplex infection in vivo; LSD1 inhibitor |
|
|
|
|
|
Cytomegalovirus |
|
|
Cat. No. |
Product
Name |
Activity |
|
2457 |
Arcyriaflavin A |
Inhibits human
CMV replication in vitro;
also Cdk4 and CaM kinase II inhibitor |
|
6258 |
CC 401 dihydrochloride |
Inhibits human CMV replication; JNK inhibitor |
|
2287 |
K-252c |
Displays antiviral activity against human CMV |
|
|
|
|
|
HIV |
|
|
Cat. No. |
Product
Name |
Activity |
|
6829 |
(R)-Shikonin |
Inhibits
HIV-1 replication |
|
4148 |
Abacavir hemisulfate |
Inhibits reverse transcriptase (RNA-dependent DNA
polymerase); antiretroviral |
|
2151 |
API-2 |
Displays antiviral activity against HIV-1 and -2 |
|
1777 |
Arctigenin |
Inhibits
HIV replication in vitro |
|
4150 |
Azidothymidine |
Selectively inhibits HIV reverse transcriptase
(RNA-dependent DNA polymerase) |
|
2711 |
Bay 55-9837 |
Inhibits HIV-1 viral replication; VPAC2 agonist |
|
5009 |
BMS 509744 |
Inhibits
HIV infection of primary CD4+ T
cells |
|
2423 |
DAPTA |
Inhibits HIV-1 viral cell entry |
|
6710 |
Darunavir |
Highly potent HIV protease inhibitor |
|
4149 |
Delavirdine mesylate |
Selectively inhibits HIV reverse transcriptase
(RNA-dependent DNA polymerase) |
|
7290 |
Famotidine |
Inhibits
HIV replication in vitro;
potent H2 receptor
inverse agonist |
|
6994 |
HODHBt |
Reactivates latent HIV-1 reservoir in central memory
T cells (TCM) |
|
4596 |
IT1t dihydrochloride |
Blocks interaction of CXCR4 with the HIV envelope
protein gp120 |
|
6126 |
KRH 3955 hydrochloride |
Inhibits
replication of HIV in vitro and in vivo; CXCR4 antagonist |
|
7052 |
Lopinavir |
Highly potent and selective HIV-1 protease inhibitor |
|
3756 |
Maraviroc |
Inhibits HIV-1 cell entry; CCR5 antagonist |
|
3766 |
Nelfinavir mesylate |
Potent HIV-1 protease inhibitor |
|
5856 |
Ritonavir |
HIV-1 and HIV-2 protease inhibitor |
|
4418 |
Saquinavir mesylate |
HIV protease inhibitor |
|
4990 |
Stavudine |
Inhibis
HIV-1 replication in vitro;
nucleoside analog |
|
3666 |
Tenofovir |
Selectively inhibits HIV reverse transcriptase
(RNA-dependent DNA polymerase) |
|
|
|
|
|
Flaviviruses |
|
|
Cat. No. |
Product
Name |
Activity |
|
6652 |
NGI
1 |
Antiflaviviral;
active against Zika, West Nile and dengue viruses |
|
6045 |
NITD 008 |
Antiflaviviral; active against Zika, Dengue and
Hepatitis C viruses |
|
|
|
|
|
Influenza Viruses |
|
|
Cat. No. |
Product
Name |
Activity |
|
2404 |
Ambroxol hydrochloride |
Inhibits
influenza (H3N2) viral replication; Na+ channel blocker |
|
7225 |
Favipiravir |
Displays antiviral activity against influenza
viruses; viral RNA-dependent RNA polymerase inhibitor |
|
3988 |
Hesperadin hydrochloride |
Displays broad spectrum antiviral activity against
influenza viruses |
|
7224 |
Oseltamivir phosphate |
Influenza virus neuraminidase inhibitor; antiviral
prodrug |
|
4611 |
PBP 10 |
Displays antiviral activity against influenza viruses |
|
4107 |
Probenecid |
Inhibits
influenza A infection in vitro and in vivo; MRP and OAT3 inhibitor |
|
1125 |
Quercetin |
Non-selective PI 3-kinase inhibitor; blocks cellular
entry by influenza A virus |
|
1138 |
Thapsigargin |
Inhibits
influenza A infection in vitro; SERCA inhibitor |
|
7187 |
Zanamivir |
Potent influenza virus neuraminidase inhibitor |
|
|
|
|
|
Hepatitis Viruses |
|
|
Cat. No. |
Product
Name |
Activity |
|
5741 |
25-Hydroxycholesterol |
Inhibits
hepatitis C viral life cycle; also α-crystallin (cryAB) chaperone |
|
6974 |
BMS 986094 |
Hepatitis C virus RNA-dependent RNA polymerase NS5b
inhibitor |
|
6234 |
Entecavir |
Potent and selective hepatitis B reverse
transcriptase (RNA-dependent DNA polymerase) inhibitor |
|
6045 |
NITD 008 |
Inhibits cell entry of HCV; also active against
Dengue and Zika viruses |
|
6658 |
Telaprevir |
Hepatitis C virus (HCV) protease NS3/4A inhibitor |
|
|
|
|
|
Others |
|
|
Cat. No. |
Product
Name |
Activity |
|
5985 |
AKT Inhibitor IV |
Displays
broad antiviral activity against negative-stranded RNA viruses |
|
5736 |
Aphidicolin |
Antiviral; inhibits DNA polymerase α, β and ε |
|
7235 |
Arbidol |
Broad spectrum antiviral |
|
2743 |
Caffeic acid phenethyl ester |
Antiviral; inhibits NF-κB activation |
|
2483 |
Costunolide |
Antiviral; human telomerase inhibitor |
|
1437 |
D609 |
Antiviral; PC-PLC inhibitor |
|
5601 |
DMXAA |
Antiviral; mSTING antagonist |
|
7231 |
EIDD 1931 |
Viral RNA-dependent RNA polymerase inhibitor; broad
spectrum antiviral nuceloside prodrug |
|
7342 |
Emetine dihydrochloride |
Inhibits replication of a broad range of RNA and DNA
viruses, including SARS-Cov-2 and Zika |
|
6494 |
Galangin |
Broad spectrum antiviral; induces autophagy and
inhibits TRPC5 |
|
7229 |
Galidesivir dihydrochloride |
Broad spectrum antiviral nucleotide; inhibits viral
RNA-dependent RNA polymerase |
|
7227 |
GS 441524 |
Viral RNA-dependent RNA polymerase (RdRp) inhibitor |
|
3700 |
Imiquimod |
Displays antiviral activity; immunomodulator |
|
2307 |
Leukotriene B4 |
Displays antiviral activity against DNA viruses and
retroviruses |
|
5604 |
MI
14 |
Displays antiviral activity against single-stranded
positive sense RNA viruses |
|
3117 |
Miglustat hydrochloride |
Displays broad spectrum antiviral activity;
α-glucosidase I and II inhibitor |
|
1505 |
Mycophenolic acid |
Antiviral and immunosuppressant |
|
7234 |
Nitazoxanide |
Broad spectrum antiviral and antiparasitic |
|
3354 |
PF 429242 dihydrochloride |
Displays antiviral activity; competitive inhibitor of
SREBP site 1 protease |
|
7226 |
Remdesivir |
Broad spectrum antiviral nucelotide prodrug; viral
RNA-dependent RNA polymerase inhibitor |
|
4536 |
Resiquimod |
Antiviral and proimflammatory; TLR7 agonist |
|
4501 |
Ribavirin |
Antiviral guanosine ribonucleoside analog |
|
3356 |
WR 1065 dihydrochloride |
Displays
broad spectrum antiviral activity in vitro |