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항바이러스제 | Antiviral Inhibitors | SARS-CoV-2 Inhibitors 이미지

항바이러스제 | Antiviral Inhibitors | SARS-CoV-2 Inhibitors

Antiviral inhibitor는 바이러스 감염을 억제하고, 바이러스의 진입, 조립, 복제를 표적으로 합니다. SARS-CoV-2 infection을 억제하는 Camostat, Auranofin, Nafamostat등을 확인하세요.

특징

 

  • 바이러스 감염을 억제하고, 바이러스의 진입, 조립, 복제를 표적으로 하는 약물을 소개합니다.
  • DNA 중합 억제, protease 억제, 바이러스 복제 차단 등의 항바이러스 매카니즘에 관여합니다.
  • HIV, CMV와 같은 viral infection의 치료에도 사용됩니다.
  • Antiviral Target Files

         - Coronavirus Antivirals 

         - Herpes Simplex Viruses

         - Cytomegalovirus

         - HIV

         - Flaviviruses

         - Influenza Viruses 

         - Hepatitis Viruses

         - Non-selective Antivirals



주요 제품
Coronavirus
Cat. No. Product Name Activity
4274 AP 24534 Identified as targeting human proteins in the SARS-CoV-2 interactome
7283 Apilimod dimesylate Inhibits cellular entry by SARS-CoV-2, MERS-CoV and MHV S pseudovirions
7235 Arbidol Inhibits replication of SARS-CoV-2 in vitro; broad spectrum antiviral
4600 Auranofin Inhibits SARS-CoV-2 infection in vitro
3771 Azithromycin Predicted to disrupt binding of SARS-CoV-2 spike protein to ACE2
7222 Baricitinib In silico modelling predicts inhibition of SARS-CoV-2 cell entry; highly potent JAK inhibitor
3193 Camostat mesylate Inhibits entry of SARS-Cov-2 into lung cells; TMPRSS2 inhibitor
4109 Chloroquine diphosphate Inhibits SARS-CoV-2 infection in vitro
6357 Ciclesonide Inhibits replication of SARS-CoV-2 in vitro; glucocorticoid
0460 Cinanserin hydrochloride Inhibits replication of SARS-CoV; Mpro inhibitor and 5-HT2 antagonist
0970 Cycloheximide Exhibits anti-MERS-CoV activity in vitro; protein synthesis inhibitor
1101 Cyclosporin A Inhibits coronavirus replication; cyclophilin inhibitor
7223 Dabrafenib mesylate Targets human proteins in the SARS-CoV-2 interactome
1467 Daunorubicin hydrochloride Identified as targeting human proteins in the SARS-CoV-2 interactome
4583 Digoxin Exhibits anti-MERS-CoV activity in vitro; Na+/K+ ATPase inhibitor
7336 Dinaciclib  Exhibits antiviral activity against SARS-CoV-2 in vitro
3807 Disulfiram SARS-CoV-2 Mpro inhibitor; also reversibly stimulates SERCA Ca2+-ATPase
4545 E 64d Inhibts entry of SARS-CoV-2 into lung cells in combination with Camostat (Cat. No. 3193)
5245 Ebselen Inhibits SARS-CoV-2 Mpro in vitro; glutathione peroxidase mimic
6986 EG 00229 trifluoroacetate Inhibits binding of cleaved spike protein of SARS-CoV-2 to neuropilin 1 (NRP1)
7231 EIDD 1931 Inhibits MERS-CoV and SARS-CoV-2 replication in vitro
7225 Favipiravir Reduces infection rate of SARS-CoV-2 in vitro; viral RNA polymerase inhibitor
3631 FK 506 Identified as targeting human proteins in the SARS-CoV-2 interactome
7229 Galidesivir dihydrochloride  Broad spectrum antiviral nucleotide; inhibits coronavirus replication in vitro
3259 Gemcitabine hydrochloride Inhibits replication of coronaviruses; DNA synthesis inhibitor
7280 GRL 0617 Coronavirus PLpro inhibitor
7227 GS 441524 Displays antiviral activity against MERS-CoV, SARS-CoV and SARS-CoV-2
1416 Homoharringtonine Inhibits SARS-CoV-2 infection in vitro; inhibits protein synthesis
5648 Hydroxychloroquine sulfate Inhibits SARS-CoV-2 viral infection in vitro
5906 Imatinib mesylate Inhibits replication of SARS-CoV and MERS-CoV in vitro
1708 Indomethacin Identified as targeting human proteins in the SARS-CoV-2 interactome
1260 Ivermectin Inhibits replication of SARS-Cov-2 in vitro; antiparasitic and antiviral
2959 Lercanidipine hydrochloride Exhibits anti-MERS-CoV activity in vitro; CaV1.x blocker
3765 Linezolid Identified as targeting human proteins in the SARS-CoV-2 interactome; antibiotic
0840 Loperamide hydrochloride Inhibits replication of coronaviruses in vitro
7052 Lopinavir Inhibits SARS-CoV-2 replication in vitro; highly potent and selective HIV-1 protease inhibitor
6819 Mefloquine hydrochloride Exhibits antiviral activities against SARS-CoV-2; also Cx36 and Cx50 gap channel blocker
2864 Metformin hydrochloride Identified as targeting human proteins in the SARS-CoV-2 interactome; antidiabetic
7228 MPro 13b Coronavirus Mpro inhibitor
7230 MPro N3 Coronavirus Mpro inhibitor
3081 Nafamostat mesylate Inhibits SARS-CoV-2 infection in vitro; serine protease inhibitor
3766 Nelfinavir mesylate Exhibits anti-MERS-CoV activity in vitro; potent HIV-1 protease inhibitor
4079 Niclosamide Inhibits SARS-CoV-2 spike protein induced syncytia formation and viral replication in vitro
7234 Nitazoxanide Inhibits SARS-CoV-2 infection in vitro
2583 Omeprazole Enhances anti-SARS-CoV-2 activity of serine protease inhibitors
1076 Ouabain Exhibits anti-MERS-CoV activity in vitro; Na+/K+ ATPase inhibitor
7357 PLpro inhibitor 6 SARS-CoV and SARS-CoV-2 PLpro inhibitor
1125 Quercetin Inhibits SARS-CoV Mpro; also non-selective PI 3-kinase inhibitor
1292 Rapamycin Inhibits MERS-CoV infection; mTOR inhibitor and immunosuppressant
7226 Remdesivir Displays antiviral activity against MERS-CoV, SARS-CoV and SARS-CoV-2
4501 Ribavirin Inhibits cytopathic effect of SARS-CoV in vitro; guanosine analog and IMPDH inhibitor
5856 Ritonavir Improves outcome in an animal model of MERS-CoV infection; HIV protease inhibitor
7064 Ruxolitinib Targets human proteins in the SARS-CoV-2 interactome; potent and selective JAK1/JAK2 inhibitor
7191 Santacruzamate A Identified as targeting human host proteins that interact with SARS-CoV-2
7189 Saracatinib Inhibits MERS-CoV, other coronaviruses and dengue virus
7192 SMIP 004 S-phase kinase-associated protein 2 (SKP2) inhibitor
1138 Thapsigargin Inhibits SARS-CoV-2 infection in vitro; SERCA inhibitor
2815 Valproic acid, sodium salt Identified as targeting human proteins in the SARS-CoV-2 interactome; HDAC inhibitor
0654 Verapamil hydrochloride Targets human proteins in the SARS-CoV-2 interactome; CaV1.x blocker
Herpes Simplex Viruses
Cat. No. Product Name Activity
2513 Acyclovir Antiviral agent; active against herpes simplex viruses
6244 OG-L002 Inhibits herpes simplex infection in vivo; LSD1 inhibitor
Cytomegalovirus
Cat. No. Product Name Activity
2457 Arcyriaflavin A Inhibits human CMV replication in vitro; also Cdk4 and CaM kinase II inhibitor
6258 CC 401 dihydrochloride Inhibits human CMV replication; JNK inhibitor
2287 K-252c Displays antiviral activity against human CMV
HIV
Cat. No. Product Name Activity
6829 (R)-Shikonin Inhibits HIV-1 replication
4148 Abacavir hemisulfate Inhibits reverse transcriptase (RNA-dependent DNA polymerase); antiretroviral
2151 API-2 Displays antiviral activity against HIV-1 and -2
1777 Arctigenin Inhibits HIV replication in vitro
4150 Azidothymidine Selectively inhibits HIV reverse transcriptase (RNA-dependent DNA polymerase)
2711 Bay 55-9837 Inhibits HIV-1 viral replication; VPAC2 agonist
5009 BMS 509744 Inhibits HIV infection of primary CD4+ T cells
2423 DAPTA Inhibits HIV-1 viral cell entry
6710 Darunavir Highly potent HIV protease inhibitor
4149 Delavirdine mesylate Selectively inhibits HIV reverse transcriptase (RNA-dependent DNA polymerase)
7290 Famotidine Inhibits HIV replication in vitro; potent H2 receptor inverse agonist
6994 HODHBt Reactivates latent HIV-1 reservoir in central memory T cells (TCM)
4596 IT1t dihydrochloride Blocks interaction of CXCR4 with the HIV envelope protein gp120
6126 KRH 3955 hydrochloride Inhibits replication of HIV in vitro and in vivo; CXCR4 antagonist
7052 Lopinavir Highly potent and selective HIV-1 protease inhibitor
3756 Maraviroc Inhibits HIV-1 cell entry; CCR5 antagonist
3766 Nelfinavir mesylate Potent HIV-1 protease inhibitor
5856 Ritonavir HIV-1 and HIV-2 protease inhibitor
4418 Saquinavir mesylate HIV protease inhibitor
4990 Stavudine Inhibis HIV-1 replication in vitro; nucleoside analog
3666 Tenofovir Selectively inhibits HIV reverse transcriptase (RNA-dependent DNA polymerase)
Flaviviruses
Cat. No. Product Name Activity
6652 NGI 1 Antiflaviviral; active against Zika, West Nile and dengue viruses
6045 NITD 008 Antiflaviviral; active against Zika, Dengue and Hepatitis C viruses
Influenza Viruses
Cat. No. Product Name Activity
2404 Ambroxol hydrochloride Inhibits influenza (H3N2) viral replication; Na+ channel blocker
7225 Favipiravir Displays antiviral activity against influenza viruses; viral RNA-dependent RNA polymerase inhibitor
3988 Hesperadin hydrochloride Displays broad spectrum antiviral activity against influenza viruses
7224 Oseltamivir phosphate Influenza virus neuraminidase inhibitor; antiviral prodrug
4611 PBP 10 Displays antiviral activity against influenza viruses
4107 Probenecid Inhibits influenza A infection in vitro and in vivo; MRP and OAT3 inhibitor
1125 Quercetin Non-selective PI 3-kinase inhibitor; blocks cellular entry by influenza A virus
1138 Thapsigargin Inhibits influenza A infection in vitro; SERCA inhibitor
7187 Zanamivir Potent influenza virus neuraminidase inhibitor
Hepatitis Viruses
Cat. No. Product Name Activity
5741 25-Hydroxycholesterol Inhibits hepatitis C viral life cycle; also α-crystallin (cryAB) chaperone
6974 BMS 986094 Hepatitis C virus RNA-dependent RNA polymerase NS5b inhibitor
6234 Entecavir Potent and selective hepatitis B reverse transcriptase (RNA-dependent DNA polymerase) inhibitor
6045 NITD 008 Inhibits cell entry of HCV; also active against Dengue and Zika viruses
6658 Telaprevir Hepatitis C virus (HCV) protease NS3/4A inhibitor
Others
Cat. No. Product Name Activity
5985 AKT Inhibitor IV  Displays broad antiviral activity against negative-stranded RNA viruses
5736 Aphidicolin Antiviral; inhibits DNA polymerase α, β and ε
7235 Arbidol Broad spectrum antiviral
2743 Caffeic acid phenethyl ester Antiviral; inhibits NF-κB activation
2483 Costunolide Antiviral; human telomerase inhibitor
1437 D609 Antiviral; PC-PLC inhibitor
5601 DMXAA Antiviral; mSTING antagonist
7231 EIDD 1931 Viral RNA-dependent RNA polymerase inhibitor; broad spectrum antiviral nuceloside prodrug
7342 Emetine dihydrochloride  Inhibits replication of a broad range of RNA and DNA viruses, including SARS-Cov-2 and Zika
6494 Galangin Broad spectrum antiviral; induces autophagy and inhibits TRPC5
7229 Galidesivir dihydrochloride  Broad spectrum antiviral nucleotide; inhibits viral RNA-dependent RNA polymerase
7227 GS 441524 Viral RNA-dependent RNA polymerase (RdRp) inhibitor
3700 Imiquimod Displays antiviral activity; immunomodulator
2307 Leukotriene B4 Displays antiviral activity against DNA viruses and retroviruses
5604 MI 14 Displays antiviral activity against single-stranded positive sense RNA viruses
3117 Miglustat hydrochloride Displays broad spectrum antiviral activity; α-glucosidase I and II inhibitor
1505 Mycophenolic acid Antiviral and immunosuppressant
7234 Nitazoxanide Broad spectrum antiviral and antiparasitic
3354 PF 429242 dihydrochloride Displays antiviral activity; competitive inhibitor of SREBP site 1 protease
7226 Remdesivir Broad spectrum antiviral nucelotide prodrug; viral RNA-dependent RNA polymerase inhibitor
4536 Resiquimod Antiviral and proimflammatory; TLR7 agonist
4501 Ribavirin Antiviral guanosine ribonucleoside analog
3356 WR 1065 dihydrochloride Displays broad spectrum antiviral activity in vitro

주문정보

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS
Selinexor 7760 50 mg TOCRIS
Selinexor 7760 10 mg TOCRIS
25-Hydroxycholesterol (10 MG) 5741 10 mg TOCRIS
Aloxistatin [E-64d] 11-077 5 mg PROSCI
Boceprevir 11-075 50 mg PROSCI
Clevudine 11-076 50 mg PROSCI
Darunavir (10 MG) 6710 10 mg TOCRIS
Darunavir (50 MG) 6710 50 mg TOCRIS
Entecavir (10 MG) 6234 10 mg TOCRIS
Entecavir (50 MG) 6234 50 mg TOCRIS
Famotidine (100 MG) 7290 100 mg TOCRIS
I 432 7292 5 mg TOCRIS
Ibudilast 11-078 250 mg PROSCI
Indinavir sulfate 7196 50 mg TOCRIS
Indinavir sulfate 7196 50 mg TOCRIS
IT1t dihydrochloride (10 mg) 4596 10 mg TOCRIS
IT1t dihydrochloride (50 mg) 4596 50 mg TOCRIS
MI 14 (10 mg) 5604 10 mg TOCRIS
Miglustat hydrochloride (10 mg) 3117 10 mg TOCRIS
NGI 1 (25 MG) 6652 25 mg TOCRIS
NGI 1 (5 MG) 6652 5 mg TOCRIS
NITD008 (1 MG) 6045 1 mg TOCRIS
Oseltamivir phosphate (100 MG) 7224 100 mg TOCRIS
PF 429242 (50 mg) 3354 50 mg TOCRIS
Pritelivir 7321 50 mg TOCRIS
Saquinavir mesylate (10 mg) 4418 10 mg TOCRIS
Saquinavir mesylate (50 mg) 4418 50 mg TOCRIS
SSYA10-001 7554 50 mg TOCRIS
SSYA10-001 7554 10 mg TOCRIS
Telaprevir 11-081 50 mg PROSCI
Tenofovir (10 mg) 3666 10 mg TOCRIS
Tenofovir (50 mg) 3666 50 mg TOCRIS
Verdinexor 7569 50 mg TOCRIS
Verdinexor 7569 10 mg TOCRIS
Zanamivir (10 MG) 7187 10 mg TOCRIS
Zanamivir (50 MG) 7187 50 mg TOCRIS
전체보기
Maker
TOCRIS
Cat.No.
7760
Product
Selinexor
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7760
Product
Selinexor
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5741
Product
25-Hydroxycholesterol (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
PROSCI
Cat.No.
11-077
Product
Aloxistatin [E-64d]
Size
5 mg
Qty
Data Sheet
Maker
PROSCI
Cat.No.
11-075
Product
Boceprevir
Size
50 mg
Qty
Data Sheet
Maker
PROSCI
Cat.No.
11-076
Product
Clevudine
Size
50 mg
Qty
Data Sheet
Maker
TOCRIS
Cat.No.
6710
Product
Darunavir (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6710
Product
Darunavir (50 MG)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6234
Product
Entecavir (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6234
Product
Entecavir (50 MG)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7290
Product
Famotidine (100 MG)
Size
100 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7292
Product
I 432
Size
5 mg
Qty
Data Sheet
MSDS
Maker
PROSCI
Cat.No.
11-078
Product
Ibudilast
Size
250 mg
Qty
Data Sheet
Maker
TOCRIS
Cat.No.
7196
Product
Indinavir sulfate
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7196
Product
Indinavir sulfate
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4596
Product
IT1t dihydrochloride (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4596
Product
IT1t dihydrochloride (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5604
Product
MI 14 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3117
Product
Miglustat hydrochloride (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6652
Product
NGI 1 (25 MG)
Size
25 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6652
Product
NGI 1 (5 MG)
Size
5 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6045
Product
NITD008 (1 MG)
Size
1 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7224
Product
Oseltamivir phosphate (100 MG)
Size
100 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3354
Product
PF 429242 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7321
Product
Pritelivir
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4418
Product
Saquinavir mesylate (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4418
Product
Saquinavir mesylate (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7554
Product
SSYA10-001
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7554
Product
SSYA10-001
Size
10 mg
Qty
Data Sheet
MSDS
Maker
PROSCI
Cat.No.
11-081
Product
Telaprevir
Size
50 mg
Qty
Data Sheet
Maker
TOCRIS
Cat.No.
3666
Product
Tenofovir (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3666
Product
Tenofovir (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7569
Product
Verdinexor
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7569
Product
Verdinexor
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7187
Product
Zanamivir (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7187
Product
Zanamivir (50 MG)
Size
50 mg
Qty
Data Sheet
MSDS
전체보기

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  • Inhibitor Book Vol.4

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    다양한 Disease 및 pathway 에 관련된 inhibitor 자료 입니다.

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