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Proteasome | Deubiquitinating Enzymes Inhibitors & Modulator 이미지

Proteasome | Deubiquitinating Enzymes Inhibitors & Modulator

Proteasome, Deubiquitinating Enzyme, Ubiquitin-activating Enzyme E1에 대한 Modulator와 Inhibitor를 소개합니다.

특징   

 

  • Proteasome은 세포내 표적 단백질의 선택적이고 효율적인 가수분해를 수행합니다. 
  • Deubiquitinating enzymes (DUBs, 유비퀴틴화 효소)는 단백질-유비퀴틴 결합의 절단을 촉매합니다. 
  • Ubiquitin-activating enzyme E1은 유비퀴틴화 다단계 효소 Cascade의 첫 단계를 촉매합니다. 

 

 

주요 제품     

Proteasome Modulators
Cat. No. Product Activity
7489 TCH-165 Enhancer of 20S proteasome assembly and 20S-mediated protein degradation
Proteasome Inhibitors
Cat. No. Product Activity
7282 Bortezomib High affinity proteasome inhibitor
6033 (R)-MG 132 Potent 20S proteasome inhibitor
6781 Capzimin dimer Selective proteasome inhibitor
7188 Carfilzomib Potent irreversible proteasome inhibitor; active in vivo
2267 Lactacystin Cell-permeable, potent and selective proteasome inhibitor
1748 MG 132 Proteasome and calpain inhibitor. Inhibits NF-κB activation
Deubiquitinating Enzyme Inhibitors
Cat. No. Product Activity
6718 ±-MF 094 Selective USP30 inhibitor
7845 AZ1 USP25/28 inhibitor  Selective USP25 and USP28 inhibitor
6776 G5 Ubiquitin isopeptidase inhibitor; induces apoptosis
4285 HBX 41108 Selective USP7 inhibitor
4250 Mitoxantrone dihydrochloride USP11 inhibitor; also topoisomerase II inhibitor and PIM1 kinase inhibitor
6435 ML 323 Potent and selective USP1-UAF1 allosteric inhibitor
4485 P 22077 USP7 inhibitor
4482 PR 619 Broad spectrum DUB inhibitor
5197 Spautin 1 USP10 and USP13 inhibitor; inhibits autophagy
5179 TCID Selective ubiquitin C-terminal hydrolase-L3 (UCH-L3) inhibitor
Ubiquitin-activating Enzyme E1 Inhibitors
Cat. No. Product Activity
4993 NSC 624206 Ubiquitin-activating enzyme (E1) inhibitor
2978 PYR 41 Ubiquitin-activating enzyme (E1) inhibitor

 

 

주문정보

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS
(+/-)-MF 094 6718 5 mg TOCRIS
(R)-MG 132 (10 mg) 6033 10 mg TOCRIS
AZ1 USP25/28 inhibitor 7845 50 mg TOCRIS
AZ1 USP25/28 inhibitor 7845 10 mg TOCRIS
Bortezomib (25 mg) 7282 25 mg TOCRIS
Bortezomib (5 mg) 7282 5 mg TOCRIS
Capzimin dimer 6781 50 mg TOCRIS
Capzimin dimer 6781 10 mg TOCRIS
Carfilzomib (10 MG) 7188 10 mg TOCRIS
Carfilzomib (50 MG) 7188 50 mg TOCRIS
G5 (10 MG) 6776 10 mg TOCRIS
G5 (50 MG) 6776 50 mg TOCRIS
HBX 41108 (10 mg) 4285 10 mg TOCRIS
Lactacystin (200 ug) 2267 200 ug TOCRIS
MG 132 (5 mg) 1748 5 mg TOCRIS
ML 323 (25 MG) 6435 25 mg TOCRIS
ML 323 (5 MG) 6435 5 mg TOCRIS
NSC 624206 (10 mg) 4993 10 mg TOCRIS
NSC 624206 (50 mg) 4993 50 mg TOCRIS
P 22077 (10 mg) 4485 10 mg TOCRIS
P 22077 (50 mg) 4485 50 mg TOCRIS
PR 619 (10 mg) 4482 10 mg TOCRIS
PR 619 (50 mg) 4482 50 mg TOCRIS
PYR 41 (10 mg) 2978 10 mg TOCRIS
Spautin 1 (10 mg) 5197 10 mg TOCRIS
Spautin 1 (50 mg) 5197 50 mg TOCRIS
TCH-165 7489 10 mg TOCRIS
TCH-165 7489 50 mg TOCRIS
전체보기
Maker
TOCRIS
Cat.No.
6718
Product
(+/-)-MF 094
Size
5 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6033
Product
(R)-MG 132 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7845
Product
AZ1 USP25/28 inhibitor
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7845
Product
AZ1 USP25/28 inhibitor
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7282
Product
Bortezomib (25 mg)
Size
25 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7282
Product
Bortezomib (5 mg)
Size
5 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6781
Product
Capzimin dimer
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6781
Product
Capzimin dimer
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7188
Product
Carfilzomib (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7188
Product
Carfilzomib (50 MG)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6776
Product
G5 (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6776
Product
G5 (50 MG)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4285
Product
HBX 41108 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
2267
Product
Lactacystin (200 ug)
Size
200 ug
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
1748
Product
MG 132 (5 mg)
Size
5 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6435
Product
ML 323 (25 MG)
Size
25 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6435
Product
ML 323 (5 MG)
Size
5 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4993
Product
NSC 624206 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4993
Product
NSC 624206 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4485
Product
P 22077 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4485
Product
P 22077 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4482
Product
PR 619 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4482
Product
PR 619 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
2978
Product
PYR 41 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5197
Product
Spautin 1 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5197
Product
Spautin 1 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7489
Product
TCH-165
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7489
Product
TCH-165
Size
50 mg
Qty
Data Sheet
MSDS
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Cat.No.
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Size
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