AXOL 감각뉴런 | Sensory Neuron Progenitors & Medium | 통증연구

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제품 상세

Pain research (통증연구)에 이용되는 Human iPSC-derived sensory neurons Progenitor cell을 소개합니다.

프린트 제품 문의

특징

Sensory Neuron (감각뉴런)은 감각 기관에서 받아들인 정보를 중추 신경계인 뇌와 척수로 전달하는 뉴런입니다. Axol Human iPSC-Sensory Neuron Progenitors는 small molecule을 이용하여 분화된 iPSC유래 감각신경세포로, glass나 plastic상에서 endpoint assay를 수행하기 위해 고안된 sensory maintenance medium과 coating reagent를 사용하여 최적화된 세포 배양 시스템을 제공합니다.
통각(nociception) 및 감각 습득에 관련된 다양한 channel을 발현합니다.
1) Voltage gated sodium ion channel (Nav1.7)
2) TTX-resistant channel (Nav1.8 / Nav 1.9)
3) Temperature sensitive channel (TRPV1, TRPM8)
4) 매운맛, 쓴맛, 얼얼함, 쓰라림, 추위 sensor (TRPA1)
배양하여 연구하고자 하는 development stage를 결정할 수 있습니다.
통증 완화를 위한 약물 표적, 말초 신경계 및 만성 통증의 장애를 조사하는데도 적합합니다.

사양

Starting material	Cord blood CD34+ cells
Donor gender	Male
Donor age at sampling	Newborn
HLA serotype	A29 A68, B38(Bw4) B44(Bw4), Cw8 Cw12
Karyotype	Normal
Reprogramming method	Episomal vector
Induction method	Monolayer & chemically defined medium
Genetic modification	None
Cell type	iPSC-derived sensory neuron progenitors
Growth properties	Adherent

제품

Cat. No.	Product	Format
ax0555	Human iPSC-derived Sensory Neuron Progenitors	≥3.2 million cells/vial
ax0055	Human iPSC-derived Sensory Neuron Progenitors	≥0.5 million cells/vial
ax0158	Sensory Neuron Maturation Maximizer Medium Kit	250 Ml Media (ax0060) + Supplement (ax0058)
ax0157	Human iPSC-Derived Sensory Neuron Maximizer Kit	Cell (ax0055) + Coating (ax0053) + Growth factor
ax0060	Sensory Neuron Maintenance Medium	250 mL
ax0058	Sensory Maturation Maximizer Supplement	1 mL
ax0033	Neural Plating medium	30 mL
ax0053	SureBond-XF	1 mL
ax139855 (10 μg)	Recombinant Human Glial-Derived Neurotrophic Factor (GDNF)	10 μg Lyophilized Powder
ax139800 (10 μg)	Recombinant Human Brain-Derived Neurotrophic Factor (BDNF)	10 μg Lyophilized Powder
ax139789 (20 μg)	Recombinant Human Nerve Growth Factor (NGF)	20 μg Lyophilized Powder
ax139811 (10 μg)	Recombinant Human Neurotrophin-3 (NT-3)	10 μg Lyophilized Powder

참고 데이터

관련 자료

Protocol

Publications

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
Product	Cat.No.	Size	Maker
Human iPSC-Derived Sensory Neuron Progenitors	ax0555-kit	1 kit	AXOL
Human iPSC-Derived Sensory Neuron Progenitors (Male) 0.5 x 10e6	ax0055	1 vial	AXOL
Human iPSC-Derived Sensory Neuron Progenitors (Male) 3.2 x 10e6	ax0555-cells	1 vial	AXOL
Human iPSC-Derived Sensory Neuron Maximizer Kit	ax0157	1 kit	AXOL
Sensory Maturation Maximizer Supplement	ax0058	1 ml	AXOL
Sensory Neuron Maintenance Medium	ax0060	250 ml	AXOL
Sensory Neuron Maturation Maximizer Medium Kit	ax0158	1 kit	AXOL

1
Maker	AXOL
Cat.No.	ax0555-kit
Product	Human iPSC-Derived Sensory Neuron Progenitors
Size	1 kit
Qty
Data Sheet

2
Maker	AXOL
Cat.No.	ax0055
Product	Human iPSC-Derived Sensory Neuron Progenitors (Male) 0.5 x 10e6
Size	1 vial
Qty
Data Sheet

3
Maker	AXOL
Cat.No.	ax0555-cells
Product	Human iPSC-Derived Sensory Neuron Progenitors (Male) 3.2 x 10e6
Size	1 vial
Qty
Data Sheet

4
Maker	AXOL
Cat.No.	ax0157
Product	Human iPSC-Derived Sensory Neuron Maximizer Kit
Size	1 kit
Qty
Data Sheet

5
Maker	AXOL
Cat.No.	ax0058
Product	Sensory Maturation Maximizer Supplement
Size	1 ml
Qty

6
Maker	AXOL
Cat.No.	ax0060
Product	Sensory Neuron Maintenance Medium
Size	250 ml
Qty

7
Maker	AXOL
Cat.No.	ax0158
Product	Sensory Neuron Maturation Maximizer Medium Kit
Size	1 kit
Qty

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
Product	Cat.No.	Size	Maker
Human GDNF	ax139855 (10 ug)	10 ug	AXOL
Human/Murine/Rat BDNF	ax139800 (10 ug)	10 ug	AXOL
Neural Plating Medium	ax0033	30 ml	AXOL
SureBond-XF	ax0053	1 ml	AXOL

Cells 세포실험 제품가이드 Vol.3

[고마바이오텍]

면역세포, 신경세포 등 다양한 세포 및 세포 실험에 사용하는 제품을 소개합니다.
Pain Research Product Guide

[TOCRIS]

Pain 연구에 관련된 small molecule 정보가 수록되어 있습니다.
Sensory Neuron Progenitors Brochure

[AXOL]

iPSC-derived Sensory Neuron에 대한 안내자료 입니다.
Sensory MATURATION MAXIMIZER Functional Characterization

[AXOL]

iPSC-derived Sensory Neuron medium supplement에 대한 안내자료 입니다.