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TRP Channel Inhibitor 이미지

TRP Channel Inhibitor

통각, 청각, 미각, 후각, 시각 및 온도 감지 등 광범위한 감각 인식 및 통합에 중요한 역할을 하는 TRP Channel에 대한 Inhibitor 및 Activator를 소개합니다.

프린트 제품 문의

특징 

 

  • Transient receptor potential (TRP) channel은 어디서나 발현되고 광범위한 자극에 의해 활성화되는 양이온 채널의 superfamily 입니다. 
  • TRP 채널은 통각, 청각, 기계감각, 미각, 후각, 시각 및 열감각을 포함하여 감각 인식 및 통합에 광범위한 역할을 합니다.  
  • TRPA1, TRPC, TRPM, TRPML, TRPP, TRPV Channel에 대한 inhibitor, activator를 제공합니다.

 

 

주요 제품 

 

TRPA1 Activator/Blocker/Antagonist/Modulators
Cat. No. Product Activity
4716 A 967079 Selective TRPA1 channel blocker
5914 AM 0902 Potent and selective TRPA1 antagonist
3296 AP 18 Reversible TRPA1 channel blocker
5178 ASP 7663 Selective TRPA1 activator
6497 GSK 2833503A Potent and selective TRPC6 and TRPC3 antagonist
2896 HC 030031 Selective TRPA1 blocker
1531 Icilin Activates a novel cold receptor. Cooling agent
6269 JT010 Potent and selective TRPA1 channel activator
4901 Optovin Reversible photoactive TRPA1 activator
3197 Polygodial TRPA1 channel activator; analgesic and antifungal
1418 Resveratrol TRPA1 activator: also cyclooxygenase inhibitor
3938 TCS 5861528 TRPA1 blocker
6875 TRPC6-PAM-C20 Selective positive allosteric modulator (PAM) of TRPC6
TRPC Channel Inhibitors/Activators
Cat. No. Product Activity
6766 AC 1903 Selective TRPC5 inhibitor
6495 AM 12 TRPC5 inhibitor
6940 BTD Selective TRPC5 activator
7170 D-GsMTx4 TRPC1/6 and Piezo2 inhibitor; resistant to proteolytic digestion
4522 Flufenamic acid Activates TRPC6; NSAID
6508 GSK 1702934A Potent and selective TRPC3/6 activator
6497 GSK 2833503A Potent and selective TRPC6 and TRPC3 antagonist
4912 GsMTx4 TRPC1 and TRPC6 inhibitor; inhibits mechanosensitive ion channels
5807 M 084 hydrochloride TRPC4 and TRPC5 inhibitor; antidepressant and anxiolytic
4732 ML 204 Selective TRPC4 inhibitor
6941 Pyr 10 Selective TRPC3 inhibitor
3751 Pyr3 Selective TRPC3 inhibitor
0768 Riluzole hydrochloride TRPC5 activator; also inhibits GABA uptake and glutamate release and blocks NaV channels
5831 SAR 7334 Potent TRPC6 inhibitor
1147 SKF 96365 hydrochloride TRPC channel inhibitor; also inhibits store-operated Ca2+ entry
6875 TRPC6-PAM-C20 Selective positive allosteric modulator (PAM) of TRPC6
TRPM Channel Agonists/Antagonists/Activators/Blockers
Cat. No. Product Activity
4999 9-Phenanthrol Selective TRPM4 blocker
6874 AMG 333 Potent and selective TRPM8 antagonist; active in vivo
3989 AMTB hydrochloride TRPM8 blocker
6724 CBA Selective TRPM4 blocker
5521 CIM 0216 Selective TRPM3 agonist
1531 Icilin Activates a novel cold receptor. Cooling agent
5324 M8 B hydrochloride Potent and selective TRPM8 channel blocker
5143 Ononetin TRPM3 blocker
5376 Pregnenolone sulfate sodium salt TRPM3 activator; also NMDA potentiator and inhibitor of GABAA receptors
5388 RQ 00203078 Potent and selective TRPM8 antagonist; orally active
4632 TC-I 2000 TRPM8 blocker
5410 TC-I 2014 Potent TRPM8 antagonist
1268 U 73122 TRPM4 activator and TRPM3 blocker; also phospholipase C inhibitor
3040 WS 12 TRPM8 agonist; cooling agent
TRPML Channel Activators & Blockers
Cat. No. Product Activity
4741 Gadolinium chloride TRPML3 blocker; stretch-activated calcium channel blocker
5547 MK6-83 TRPML channel activator
4746 ML SA1 Activator of TRPML channels
4907 SN 2 Selective TRPML3 channel activator
TRPP Channel Blockers
Cat. No. Product Activity
0890 Amiloride hydrochloride Na+ channel blocker; inhibits TRPP3 channel
3380 Benzamil NCX inhibitor; inhibits TRPP3 channel activity
3378 EIPA Inhibits TRPP3-mediated currents; also inhibits the Na+/H+ exchanger (NHE)
3379 Phenamil Inhibits TRPP3-mediated currents; also inhibits epithelial Na+ channels
TRPV Channel Agonists/Antagonists/Inhibitors/Activators
Cat. No. Product Activity
7199 (±)-Eriodictyol Potent TRPV1 antagonist; also antioxidant; activates Nrf2/ARE signaling
0462 (E)-Capsaicin TRPV agonist
5781 A 425619 Potent TRPV1 antagonist
4319 A 784168 Potent and selective TRPV1 antagonist
1116 AM 404 TRPV agonist; also anandamide transport inhibitor
4330 AMG 21629 Potent and selective TRPV1 antagonist
5995 AMG 517 Potent TRPV1 antagonist
2316 AMG 9810 Potent and selective TRPV1 competitive antagonist
1339 Anandamide Endogenous TRPV1 agonist; also cannabinoid agonist
3875 BCTC TRPV1 antagonist
0464 Capsazepine TRPV antagonist; also activator of ENaCδ
7118 cis-22a TRPV6 inhibitor
4876 Eact TRPV1 activator; also TMEM16A activator
6433 GSK 1016790A Potent TRPV4 agonist; active in vivo
5106 GSK 2193874 Potent and selective TRPV4 antagonist; orally active
4100 HC 067047 Potent and selective TRPV4 antagonist
3361 JNJ 17203212 Reversible, competitive and potent TRPV1 antagonist
1641 OLDA Potent and selective endogenous TRPV1 agonist
0934 Olvanil Potent TRPV agonist
3746 RN 1734 Selective TRPV4 antagonist
3745 RN 1747 Selective TRPV4 agonist
5678 RN 9893 hydrochloride Potent and selective TRPV4 antagonist
1439 Ruthenium Red Blocks capsaicin-activated cation channels
1615 SB 366791 Potent and selective TRPV1 competitive antagonist
6990 SET 2 Selective TRPV2 antagonist
1098 Tranilast Antiallergic; inhibits TRPV2-mediated responses
6831 TRPV3 74a Selective TRPV3 antagonist; brain penetrant

 

주문정보

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS
(E)-Capsaicin (100 mg) 0462 100 mg TOCRIS
A 425619 (10 mg) 5781 10 mg TOCRIS
A 425619 (50 mg) 5781 50 mg TOCRIS
A 784168 (10 mg) 4319 10 mg TOCRIS
A 784168 (50 mg) 4319 50 mg TOCRIS
A 967079 (10 mg) 4716 10 mg TOCRIS
A 967079 (50 mg) 4716 50 mg TOCRIS
AC 1903 (25 MG) 6766 25 mg TOCRIS
AC 1903 (5 MG) 6766 5 mg TOCRIS
AM 0902 (10 MG) 5914 10 mg TOCRIS
AM 0902 (50 MG) 5914 50 mg TOCRIS
AM 404 (10 mg) 1116 10 mg TOCRIS
AM 404 (50 mg) 1116 50 mg TOCRIS
AMG 21629 (1 mg) 4330 1 mg TOCRIS
AMG 333 (10 MG) 6874 10 mg TOCRIS
AMG 333 (50 MG) 6874 50 mg TOCRIS
AMG 517 (10 mg) 5995 10 mg TOCRIS
AMG 517 (50 mg) 5995 50 mg TOCRIS
AMG 9810 (10 mg) 2316 10 mg TOCRIS
AMG 9810 (50 mg) 2316 50 mg TOCRIS
Amiloride hydrochloride (100 mg) 0890 100 mg TOCRIS
AMTB hydrochloride (10 mg) 3989 10 mg TOCRIS
AMTB hydrochloride (50 mg) 3989 50 mg TOCRIS
Anandamide (5 mg) 1339 5 mg TOCRIS
AP 18 (10 mg) 3296 10 mg TOCRIS
AP 18 (50 mg) 3296 50 mg TOCRIS
ASP 7663 (10 mg) 5178 10 mg TOCRIS
ASP 7663 (50 mg) 5178 50 mg TOCRIS
BCTC (10 mg) 3875 10 mg TOCRIS
BCTC (50 mg) 3875 50 mg TOCRIS
Benzamil (10 mg) 3380 10 mg TOCRIS
Benzamil (50 mg) 3380 50 mg TOCRIS
BTD (10 MG) 6940 10 mg TOCRIS
BTD (50 MG) 6940 50 mg TOCRIS
Capsazepine (10 mg) 0464 10 mg TOCRIS
Capsazepine (50 mg) 0464 50 mg TOCRIS
CBA (10 MG) 6724 10 mg TOCRIS
CBA (50 MG) 6724 50 mg TOCRIS
CIM 0216 (10 mg) 5521 10 mg TOCRIS
CIM 0216 (50 mg) 5521 50 mg TOCRIS
cis-22a (10 mg) 7118 10 mg TOCRIS
cis-22a (50 mg) 7118 50 mg TOCRIS
D-GsMTx4 (100 UG) 7170 100 ug TOCRIS
Eact (10 mg) 4876 10 mg TOCRIS
Eact (50 mg) 4876 50 mg TOCRIS
EIPA (10 mg) 3378 10 mg TOCRIS
EIPA (50 mg) 3378 50 mg TOCRIS
Flufenamic acid (50 mg) 4522 50 mg TOCRIS
Gadolinium chloride (50 mg) 4741 50 mg TOCRIS
GSK 1016790A (10 MG) 6433 10 mg TOCRIS
전체보기
Maker
TOCRIS
Cat.No.
0462
Product
(E)-Capsaicin (100 mg)
Size
100 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5781
Product
A 425619 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5781
Product
A 425619 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4319
Product
A 784168 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4319
Product
A 784168 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4716
Product
A 967079 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4716
Product
A 967079 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6766
Product
AC 1903 (25 MG)
Size
25 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6766
Product
AC 1903 (5 MG)
Size
5 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5914
Product
AM 0902 (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5914
Product
AM 0902 (50 MG)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
1116
Product
AM 404 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
1116
Product
AM 404 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4330
Product
AMG 21629 (1 mg)
Size
1 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6874
Product
AMG 333 (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6874
Product
AMG 333 (50 MG)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5995
Product
AMG 517 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5995
Product
AMG 517 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
2316
Product
AMG 9810 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
2316
Product
AMG 9810 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
0890
Product
Amiloride hydrochloride (100 mg)
Size
100 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3989
Product
AMTB hydrochloride (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3989
Product
AMTB hydrochloride (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
1339
Product
Anandamide (5 mg)
Size
5 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3296
Product
AP 18 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3296
Product
AP 18 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5178
Product
ASP 7663 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5178
Product
ASP 7663 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3875
Product
BCTC (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3875
Product
BCTC (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3380
Product
Benzamil (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3380
Product
Benzamil (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6940
Product
BTD (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6940
Product
BTD (50 MG)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
0464
Product
Capsazepine (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
0464
Product
Capsazepine (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6724
Product
CBA (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6724
Product
CBA (50 MG)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5521
Product
CIM 0216 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5521
Product
CIM 0216 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7118
Product
cis-22a (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7118
Product
cis-22a (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7170
Product
D-GsMTx4 (100 UG)
Size
100 ug
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4876
Product
Eact (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4876
Product
Eact (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3378
Product
EIPA (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3378
Product
EIPA (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4522
Product
Flufenamic acid (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4741
Product
Gadolinium chloride (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6433
Product
GSK 1016790A (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
전체보기

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주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS

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