고마바이오텍(주)
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제품 상세

Antibody

6.5 - 270 kDa 범위를 커버하는 3가지 컬러 밴드를 포함하며,
최대 100%까지의 transfer 효과를 개런티하는 Prestained protein ladder를 소개합니다.

특징

  

  • 약물의 독성으로 인한 부작용에 대한 분석은 임상개발 후반에 진행될 경우 비용이 많이 들고 프로젝트 일정에 상당한 영향을 줄수 있으므로, 발견과정 초기에 포괄적인 in vitro toxicology 분석을 통해 drug safety profile을 평가하는 것이 필요합니다.
  • Hepatoxocity (간독성), Cardiotoxicity (심장독성), Genotoxicity (유전독성), Cytotoxicity (세포독성), Nephrotoxicity (신장독성)에 대한 분석을 진행해 드립니다.
  • Panel service 를 통해 다양한 관련 분석을 진행할 수 있으며, 개별 서비스로도 선택할 수 있습니다.

 


서비스 패널 종류



IN VITRO TOXICOLOGY PANEL (#PSC375)
  • Ames fluctuation test
  • Micronucleus Panel
  • Cell viability (human hepatocytes)
  • CardiacProfiler Ion Channel Core Panel - Qube APC (6 Conc.)
  • Cytotoxicity (HepG2; 5 endpoints; HCA)
  • Cell viability (HRPTEpiC)

DRUG-INDUCED LIVER INJURY (DILI) PANELS - DILI Screening Panel (#P385)
  • Cell Viability (HepG2, 72-hour, CellTiter-Glo)
  • Mitotox - Cell Viability (HepG2, Galactose Medium, CellTiter-Glo)
  • Mitotox - Cell Viability (HepG2, Glucose Medium, CellTiter-Glo)

DRUG-INDUCED LIVER INJURY (DILI) PANELS - DILI Mechanistic Panel (#P385M)
  • Cell viability (human hepatocytes)
  • High Content Cytotoxicity (HepG2) - Cell number (cytotox)
  • High Content Cytotoxicity (HepG2) - Nuclear size
  • High Content Cytotoxicity (HepG2) - Mitochondrial membrane potential
  • High Content Cytotoxicity (HepG2) - Intracellular free calcium
  • High Content Cytotoxicity (HepG2) - Membrane permeability
  • BSEP inhibition (MV, 3H-taurocholic acid substrate)
  • Mitotox - Cell Viability (HepG2, Galactose Medium, CellTiter-Glo)
  • Mitotox - Cell Viability (HepG2, Glucose Medium, CellTiter-Glo)
  • FXR Functional Agonist & Antagonist activation assay
  • Phospholipidosis (HepG2, HCA)
  • Glutathione conjugate detection (liver S9, human)

Ames Test and Fluctuation Assays (#G175)
  • Ames fluctuation test (TA98 - S9)
  • Ames fluctuation test (TA98 + S9)
  • Ames fluctuation test (TA100 - S9)
  • Ames fluctuation test (TA100 + S9)
  • Ames fluctuation test (TA1535 - S9)
  • Ames fluctuation test (TA1535 + S9)
  • Ames fluctuation test (TA1537-S9)
  • Ames fluctuation test (TA1537 + S9)

In Vitro Micronucleus Assays (#G344)
  • Micronucleus Panel
  • Micronucleus (CHO - S9, HCA)
  • Micronucleus (CHO + S9, HCA)

Hepatotoxicity Assays
  • Cellular Stress (PHH; Cell Viability; HSP27; Apoptosis) (#970010)
  • Cytotoxicity (PHH; Cell Viability; ROS; MMP) (#970011)
  • Cytotoxicity (PHH; Cell Viability; Apoptosis) (#970012)
  • Cell viability (human hepatocytes) (#533)
  • BSEP Human Transporter Cell Based Assay (#3745)
  • MRP Human Transporter Inhibition Assay (#3879)

Cardiotoxicity Assays
  • CardiacProfiler Ion Channel Core Panel - Qube APC (1 Conc.)
  • CardiacProfiler Ion Channel Core Panel - Qube APC (6 Conc.)
  • CardiacProfiler Ion Channel Full Panel - Qube APC (1 Conc.)
  • CardiacProfiler Ion Channel Full Panel - Qube APC (6 Conc.)
  • hERG Potassium Channel Assay - Qube APC (1 Conc.)
  • hERG Potassium Channel Assay - Qube APC (6 Conc.)
  • hCav1.2 (L-type) Calcium Channel Assay - Qube APC (1 Conc.)
  • hCav1.2 (L-type) Calcium Channel Assay - Qube APC (6 Conc.)
  • hNav1.5 Sodium Channel Assay - Qube APC (1 Conc.)
  • hNav1.5 Sodium Channel Assay - Qube APC (6 Conc.)
  • hNav1.5 Late Current Sodium Channel Assay - Qube APC (1 Conc.)
  • hNav1.5 Late Current Sodium Channel Assay - Qube APC (6 Conc.)
  • hKCNQ1 /hminK Potassium Channel Assay - Qube APC (1 Conc.)
  • hKCNQ1 /hminK Potassium Channel Assay - Qube APC (6 Conc.)
  • hKir2.1 Potassium Channel Assay - Qube APC (1 Conc.)
  • hKir2.1 Potassium Channel Assay - Qube APC (6 Conc.)
  • hKv4.3 /hKChIP2 Potassium Channel Assay - Qube APC (1 Conc.)
  • hKv4.3 /hKChIP2 Potassium Channel Assay - Qube APC (6 Conc.)

Cytotoxicity Assays 
  • Cytotoxicity Panel (HepG2; 5 endpoints; HCA) (#G202)
  • Cytotoxicity (NHDF-neo; Cell Viability; Apoptosis; Cell Cycle) (#970021)
  • Cellular Stress (NHDF-neo; Cell Viability; HSP27) (#970020)
  • Cytotoxicity (HUVEC; Cell Viability; Apoptosis; Cell Cycle) (#970520)
  • Cellular Stress (HUVEC; Cell Viability; HSP27) (#970040)
  • Cytotoxicity (HUMSC; Cell Viability; Apoptosis; Cell Cycle) (#970041)
  • Cellular Stress (HUMSC; Cell Viability; HSP27) (#970050)
  • Cytotoxicity (custom) (#1537)
  • Cytotoxicity Panel (#P213)
  • Cell Viability (HUMSC) (#4574)
  • Cell Viability (HUVEC) (#4575)
  • Cell Viability (NHDF-neo) (#4576)

Nephrotoxicity Assays 
  • Cellular Stress (HRPTEpiC; Cell Viability; HSP27; KIM1) (#970030)
  • Cytotoxicity (HRPTEpiC; Cell Viability; Apoptosis; Cell Cycle) (#970031)
  • Cell Viability (#4573)


주문정보

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet
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추천제품

자료

웨비나/Video

TOP

제품 문의

0.5 ml Elite Pre-stained Protein Ladder (2 x 0.25 ml) PAL-EPL-500 0.5ml 500
Maker
Cat.No.
Product
Size
Qty
Data Sheet

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