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Bromodomain Inhibitor 스크리닝 서비스 이미지

Bromodomain Inhibitor 스크리닝 서비스

Eurofins Discovery사의 BROMOscan은 테스트 화합물과 bromodomain과의 binding 분석을 제공하고, EPIscan은 세포를 기반으로 bromodomain 및 histone methyltransferase(HMT)를 분석합니다.

BROMOscan Binding Assay 서비스

  

  • BROMOscan은 소분자 bromodomain inhibitor를 식별하기 위한 새로운 leading platform 입니다. 
  • Bromodomain은 질병과 관련된 여러 bromodomain 함유 단백질과 함께 소분자 억제제 약물 발견에서 중요한 새로운 약물 표적이 되고 있는 epigenetic "reader" protein 입니다. 
  • Bromodomain-containing 단백질에 대한 binding assay를 제공합니다.
  • Dynamic range : Kd <100 pM to >10uM
  • Bromo ELECT 서비스 리포트 샘플

서비스 목록 

Service Cat. No.
ATAD2A Human Bromodomain-Containing BROMOscan ELECT Binding LeadHunter Assay 88-0005-1489
ATAD2A Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1489
ATAD2B Human Bromodomain-Containing BROMOscan ELECT Binding LeadHunter Assay 88-0005-1482
ATAD2B Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1482
BAZ2A Human Bromodomain-Containing BROMOscan ELECT Binding LeadHunter Assay 88-0005-1483
BAZ2A Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1483
BAZ2B Human Bromodomain-Containing BROMOscan ELECT Binding LeadHunter Assay 88-0005-1470
BAZ2B Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1470
BRD1 Human Bromodomain-Containing BROMOscan ELECT Binding LeadHunter Assay 88-0005-1471
BRD1 Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1471
BRD2 (1) Human Bromodomain-Containing BROMOscan ELECT Binding LeadHunter Assay 88-0005-1472
BRD2 (1) Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1472
BRD2 (1,2) Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1502
BRD2 (2) Human Bromodomain-Containing BROMOscan ELECT Binding LeadHunter Assay 88-0005-1473
BRD2 (2) Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1473
BRD3 (1) Human Bromodomain-Containing BROMOscan ELECT Binding LeadHunter Assay 88-0005-1474
BRD3 (1) Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1474
BRD3 (1,2) Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1503
BRD3 (2) Human Bromodomain-Containing BROMOscan ELECT Binding LeadHunter Assay 88-0005-1475
BRD3 (2) Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1475
BRD4 (1) Human Bromodomain-Containing BROMOscan ELECT Binding LeadHunter Assay 88-0005-1476
BRD4 (1) Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1476
BRD4 (1,2) Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1504
BRD4 (2) Human Bromodomain-Containing BROMOscan ELECT Binding LeadHunter Assay 88-0005-1477
BRD4 (2) Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1477
BRD4 (Full-Length,Short-Iso.) Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1505
BRD7 Human Bromodomain-Containing BROMOscan ELECT Binding LeadHunter Assay 88-0005-1495
BRD7 Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1495
BRD8 (1) Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1507
BRD8 (2) Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1508
BRD9 Human Bromodomain-Containing BROMOscan ELECT Binding LeadHunter Assay 88-0005-1490
BRD9 Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1490
BRDT (1) Human Bromodomain-Containing BROMOscan ELECT Binding LeadHunter Assay 88-0005-1478
BRDT (1) Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1478
BRDT (1,2) Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1506
BRDT (2) Human Bromodomain-Containing BROMOscan ELECT Binding LeadHunter Assay 88-0005-1479
BRDT (2) Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1479
BromoKdMAX Bromodomain BROMOscan LeadHunter Panel 88-0009-1000
BromoMAX Bromodomain BROMOscan LeadHunter Panel 88-0001-1000
BRPF1 Human Bromodomain-Containing BROMOscan ELECT Binding LeadHunter Assay 88-0005-1491
BRPF1 Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1491
BRPF3 Human Bromodomain-Containing BROMOscan ELECT Binding LeadHunter Assay 88-0005-1484
BRPF3 Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1484
CECR2 Human Bromodomain-Containing BROMOscan ELECT Binding LeadHunter Assay 88-0005-1496
CECR2 Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1496
CREBBP Human Histone Acetyltransferase (HAT) Bromodomain BROMOscan ELECT Binding LeadHunter Assay 88-0005-1480
CREBBP Human Histone Acetyltransferase (HAT) Bromodomain BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1480
FALZ Human Bromodomain-Containing BROMOscan ELECT Binding LeadHunter Assay 88-0005-1486
FALZ Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1486
GCN5L2 Human Histone Acetyltransferase (HAT) Bromodomain BROMOscan ELECT Binding LeadHunter Assay 88-0005-1497
GCN5L2 Human Histone Acetyltransferase (HAT) Bromodomain BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1497
P300 Human Histone Acetyltransferase (HAT) Bromodomain BROMOscan ELECT Binding LeadHunter Assay 88-0005-1485
P300 Human Histone Acetyltransferase (HAT) Bromodomain BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1485
PB1 (2) Human Bromodomain-Containing BROMOscan ELECT Binding LeadHunter Assay 88-0005-1492
PB1 (2) Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1492
PB1 (5) Human Bromodomain-Containing BROMOscan ELECT Binding LeadHunter Assay 88-0005-1498
PB1 (5) Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1498
PCAF Human Histone Acetyltransferase (HAT) Bromodomain BROMOscan ELECT Binding LeadHunter Assay 88-0005-1499
PCAF Human Histone Acetyltransferase (HAT) Bromodomain BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1499
SD BROMOscan Custom Assay Development LeadHunter Service 88-0010-1552
SMARCA2 Human Bromodomain-Containing BROMOscan ELECT Binding LeadHunter Assay 88-0005-1500
SMARCA2 Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1500
SMARCA4 Human Bromodomain-Containing BROMOscan ELECT Binding LeadHunter Assay 88-0005-1501
SMARCA4 Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1501
TAF1 (2) Human Bromodomain-Containing BROMOscan ELECT Binding LeadHunter Assay 88-0005-1481
TAF1 (2) Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1481
TAF1L (2) Human Bromodomain-Containing BROMOscan ELECT Binding LeadHunter Assay 88-0005-1487
TAF1L (2) Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1487
TRIM24 (Bromo) Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1509
TRIM24 (PHD, Bromo) Human Bromodomain-Containing BROMOscan ELECT Binding LeadHunter Assay 88-0005-1493
TRIM24 (PHD, Bromo) Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1493
TRIM33 (PHD, Bromo) Human PHDdomain BROMOscan ELECT Binding LeadHunter Assay 88-0005-1494
TRIM33 (PHD, Bromo) Human PHDdomain BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1494
WDR9 (2) Human Bromodomain-Containing BROMOscan ELECT Binding LeadHunter Assay 88-0005-1488
WDR9 (2) Human Bromodomain-Containing BROMOscan KdELECT Binding LeadHunter Assay 88-0007-1488



EPIscan℠ - Cell-Based Functional Assay 서비스

  • EPIscan은 cell 기반의 bromodomain 및 histone methyltransferase (HMT)를 분석하는 툴 입니다. 
  • InCELL Hunter 기술을 기반으로 하여 천연 세포 환경에서 화합물의 투과성과 결합을 직접 측정합니다. 
  • 결합 및 세포 내 효능을 기반으로 화합물을 최적화하고 주요 화합물의 치료 가능성에 대해 더 많은 정보를 제공합니다. 

서비스 목록

Service Cat. No.
BAZ2A Human Bromodomain-Containing Cell Based Agonist Binding LeadHunter Assay  85-0001P-2392AG
BRD2 (1) Human Bromodomain-Containing Cell Based Agonist Binding LeadHunter Assay  85-0001P-2397AG
BRD2 (1,2) Human Bromodomain-Containing Cell Based Agonist Binding LeadHunter Assay  85-0001P-2394AG
BRD3 (1) Human Bromodomain-Containing Cell Based Agonist Binding LeadHunter Assay  85-0001P-2399AG
BRD3 (1,2) Human Bromodomain-Containing Cell Based Agonist Binding LeadHunter Assay  85-0001P-2398AG
BRD4 (1) Human Bromodomain-Containing Cell Based Agonist Binding LeadHunter Assay  85-0001P-2400AG
BRD4 Human Bromodomain-Containing Chromatin Reader in HCT-116 Cell Based Protein Turnover LeadHunter Assay  86-0032P-2400-047
BRD4 Human Bromodomain-Containing Chromatin Reader in K562 Cell Based Protein Turnover LeadHunter Assay  86-0032P-2400-042
BRDT (1) Human Bromodomain-Containing Cell Based Agonist Binding LeadHunter Assay  85-0001P-2402AG
BRDT (1,2) Human Bromodomain-Containing Cell Based Agonist Binding LeadHunter Assay  85-0001P-2401AG
SMARCA4 Human Bromodomain-Containing Cell Based Agonist Binding LeadHunter Assay  85-0001P-2396AG
TAF1L (2) Human Bromodomain-Containing Cell Based Agonist Binding LeadHunter Assay  85-0001P-2395AG


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Eurofins DiscoverX Epigenetic Service . . EUROFINS DISCOVERX
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EUROFINS DISCOVERX
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Eurofins DiscoverX Epigenetic Service
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0.5 ml Elite Pre-stained Protein Ladder (2 x 0.25 ml) PAL-EPL-500 0.5ml 500
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