고마바이오텍(주)

로그인이 필요합니다.

Category 전체보기
전기영동 > 단백질 전기영동 전기영동 > 헥산 전기영동
Cat. No.전체보기

검색 결과가 없습니다.

Product전체보기

검색 결과가 없습니다.

Brand전체보기

검색 결과가 없습니다.

제품 상세

Antibody

6.5 - 270 kDa 범위를 커버하는 3가지 컬러 밴드를 포함하며,
최대 100%까지의 transfer 효과를 개런티하는 Prestained protein ladder를 소개합니다.

프린트 제품 문의

특징

 

  • Receptor Tyrosine Kinases (RTK)는 효소 연결 수용체중 하나로, 리간드가 붙으면 tyrosine kinase 활성을 유도합니다. 
  • 세포외부의 리간드 결합 도메인, 단일 membrane-spanning 도메인, 세포내부의 tyrosine kinase 도메인의 3구성으로 이루어 집니다. 
  • 리간드는 일반적으로 유기체의 다른 곳에서 생성되는 확산성 펩타이드나 작은 단백질이며, 일반적으로 growth factor, cytokine, hormone등이 해당됩니다. 


타겟

 

  • ALK
  • EGFR
  • Eph Receptors
  • FGFR
  • FLT3
  • Insulin and Insulin-like Receptors
  • MET Receptors
  • PDGFR
  • Trk Receptors
  • VEGFR


주요 제품

ALK 
Cat. No. Product Activity
5310 ASP 3026 Potent anaplastic lymphoma kinase (ALK) inhibitor; also potent ACK inhibitor
6905 Ceritinib Highly potent ALK inhibitor; also potently inhibits IR, IGF1R, STK22D and FLT3
4368 Crizotinib Potent c-MET/ALK inhibitor
5111 GSK 1838705 Potent ALK inhibitor; also IR and IGF1R inhibitor
5098 KRCA 0008 Potent Ack1 and ALK dual inhibitor; orally bioavailable
1614 SB 431542 Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7
3263 SB 505124 Selective inhibitor of TGF-βRI, ALK4 and ALK7
EGFR
Cat. No. Product Activity
5318 AEE 788 Potent EGFR and VEGFR inhibitor
6812 Afatinib dimaleate Potent dual specificity EGFR/HER2 inhibitor; active in vivo
1276 AG 1478 hydrochloride Highly potent EGFR-kinase inhibitor
414 AG 490 EGFR-kinase inhibitor. Also JAK2, JAK3 inhibitor
1555 AG 825 Selective ErbB2 inhibitor
2416 BIBX 1382 dihydrochloride Highly selective EGFR-kinase inhibitor
5022 BMS 599626 dihydrochloride Potent, selective EGFR and ErbB2 inhibitor
5916 Canertinib dihydrochloride Potent EGFR kinase inhibitor
3360 CGP 52411 EGFR inhibitor. Also inhibits Aβ42 fibril formation
6231 Dacomitinib Potent irreversible pan ErbB inhibitor
4502 DIM Inhibits EGFR activation; also induces apoptosis
7424 EMI 48  Inhibitor of EGFR mutants
7194 Erlotinib Hydrochloride  Potent, reversible EGFR tyrosine kinase inhibitor
1110 Genistein EGFR kinase inhibitor. Also estrogen and PPARγ ligand
2239 GW 583340 dihydrochloride Potent dual EGFR/ErbB2 inhibitor; orally active
3580 HKI 357 Dual irreversible inhibitor of ErbB2 and EGFR
3000 Iressa Orally active, selective EGFR inhibitor
6962 JBJ-03-142-02 Highly potent EGFR and ErbB2 inhibitor; inhibts wild type and mutated receptors
3352 JNJ 28871063 hydrochloride Potent ErbB receptor family inhibitor
6811 Lapatinib Potent and selective dual ErbB2 (HER-2) and EGFR inhibitor
1331 Lavendustin A EGFR, p60c-src inhibitor
7371 Neratinib  Potent HER2 receptor tyrosine kinase and EGFR kinase inhibitor
1037 PD 153035 hydrochloride EGFR-kinase inhibitor
2615 PD 158780 Potent ErbB receptor family inhibitor
6349 Pelitinib Potent and irreversible EGFR inhibitor; orally bioavailable
4941 PKI 166 hydrochloride Potent EGFR-kinase inhibitor
2794 PP 3 EGFR-kinase inhibitor. Also Src kinase negative control
3599 TAK 165 Potent and selective ErbB2 inhibitor
3115 WHI-P 154 Potent EGFR inhibitor. Also inhibits JAK3
Eph Receptors
Cat. No. Product Activity
5290 KYL EphA4 kinase inhibitor; neuroprotective
FGFR 
Cat. No. Product Activity
4274 AP 24534 Potent multi-kinase and pan-Bcr-Abl inhibitor
7454 Cediranib  Potent inhibitor of VEGFR, PDGFR and FGFR
4002 FIIN 1 hydrochloride Potent, irreversible FGFR inhibitor
7049 Nintedanib Potent VEGFR, PDGFR and FGFR inhibitor
3724 PD 161570 Selective FGFR inhibitor
3785 PD 166285 dihydrochloride FGFR, PDGFRβ and Src inhibitor; also inhibits Wee1
3044 PD 173074 FGFR1 and -3 inhibitor
3300 SU 5402 Potent FGFR and VEGFR inhibitor
3335 SU 6668 FGFR, VEGFR and PDGFR inhibitor
FMS-like receptor tyrosine kinase-3 (FLT3) 
Cat. No. Product Activity
5013 AC 710 Potent FLT3 inhibitor; also inhibits other PDGFR family members
6905 Ceritinib Potent FLT3 inhibitor; also potently inhibits ALK, IR, IGF1R and STK22D
6056 GSK 1363089 Potent FLT3 inhibtor; also inhibits of MET, VEGFR2, Ron and AXL
5260 KG 5 PDGFRβ, B-Raf, c-Raf, FLT3 and KIT inhibitor; antiangiogenic
3395 Lestaurtinib FLT3, JAK2 and TrkA inhibitor; also inhibits AurA and AurB
6788 Quizartinib Highly potent FLT3 inhibitor
6814 Sorafenib Flt-3 inhibitor; also inhibits Raf-1, VEGFR-2, VEGFR-3, PDGFR-β and cKIT
3037 SU 5416 Inhbitor of VEGFR, KIT, RET, MET and FLT3
2591 TCS 359 Potent FLT3 inhibitor
5422 XL 184 Potent FLT3 inhibitor; also inhibits other RTKs
Insulin and Insulin-like Receptors
Cat. No. Product Activity
4774 BMS 536924 Dual IR/IGF1R inhibitor
6905 Ceritinib Potent IR and IGF1R inhibitor; also potently inhibits ALK, STK22D and FLT3
1819 Demethylasterriquinone B1 Selective insulin RTK activator
5111 GSK 1838705 Potent IR and IGF1R inhibitor; also inhibits anaplastic lymphoma kinase (ALK)
3435 Insulin (human) recombinant expressed in yeast
5247 NVP ADW 742 ATP-competitive inhibitor of IGF1R
2956 Picropodophyllotoxin Selective IGF1R inhibitor
2768 PQ 401 IGF1R inhibitor
MET Receptor
Cat. No. Product Activity
4368 Crizotinib Potent c-MET/ALK inhibitor
6056 GSK 1363089 Potent inhibitor of MET, VEGFR2, Ron and AXL
1683 K 252a Receptor tyrosine kinase inhibitor, inhibits MET
4239 PF 04217903 mesylate Highly selective MET inhibitor
2693 PHA 665752 Potent and selective MET inhibitor
5356 SGX 523 Selective and potent c-MET kinase inhibitor
3037 SU 5416 MET inhibitor. Also inhibits KIT, RET, VEGFR and FLT3
5422 XL 184 Potent c-MET inhibitor; also inhibits other RTKs
PDGFR
Cat. No. Product Activity
5013 AC 710 Potent and selective PDGFR family inhibitor
4274 AP 24534 Potent multi-kinase and pan-Bcr-Abl inhibitor
7454 Cediranib  Potent inhibitor of VEGFR, PDGFR and FGFR
5993 CP 673451 Potent and selective PDGFR inhibitor
1222 DMPQ dihydrochloride Potent, selective inhibitor of PDGFRβ
6056 GSK 1363089 Potent PDGFR inhibtor; also inhibits of MET, VEGFR2, Ron and AXL
5906 Imatinib mesylate PDGFR inhibitor; also inhibits v-Abl tyrosine kinase and c-kit
6976 JNJ 10198409 Potent PDGFRα and PDGFRβ inhbitor; also inhibits c-Abl, Lck, c-Src and Fyn kinases
5260 KG 5 PDGFRβ, B-Raf, c-Raf, FLT3 and KIT inhibitor; antiangiogenic
7049 Nintedanib Potent VEGFR, PDGFR and FGFR inhibitor
3785 PD 166285 dihydrochloride PDGFRβ, FGFR and Src inhibitor; also inhibits Wee1
6814 Sorafenib PDGFR-β inhibitor; also inhibits Raf-1, VEGFR-2, VEGFR-3, Flt-3 and cKIT
3304 SU 16f Potent and selective PDGFRβ inhibitor
3335 SU 6668 PDGFR, VEGFR and FGFR inhibitor
3768 Sunitinib malate Potent VEGFR, PDGFRβ and KIT inhibitor
Trk Receptors
Cat. No. Product Activity
3826 7,8-Dihydroxyflavone TrkB agonist
4456 Amitriptyline hydrochloride TrkA/B agonist; also a serotonin and noradrenaline uptake inhibitor
4781 ANA 12 TrkB receptor antagonist
2837 BDNF (human) Activates TrkB and p75 receptors
5062 Cyclotraxin B TrkB receptor antagonist
1819 Demethylasterriquinone B1 Trk receptor activator; also selective insulin RTK activator
4559 GNF 5837 Potent Trk inhibitor; inhibits TrkA, TrkB and TrkC
2238 GW 441756 Potent, selective TrkA inhibitor
5961 HIOC Selective TrkB receptor agonist; neuroprotectant
3395 Lestaurtinib TrkA, JAK2 and FLT3 inhibitor; also inhibits AurA and AurB
4607 LM 22A4 Potent TrkB agonist
6037 LM22B 10 TrkB and TrkC agonist; brain penetrant
6115 PF 06273340 Potent and selective pan-Trk inhibitor; peripherally restricted
VEGFR
Cat. No. Product Activity
5318 AEE 788 Potent VEGFR and EGFR inhibitor
4274 AP 24534 Potent multi-kinase and pan-Bcr-Abl inhibitor
4350 Axitinib Potent VEGFR-1, -2 and -3 inhibitor
6069 BMS 605541 Potent VEGFR-2 inhibitor
7454 Cediranib  Potent inhibitor of VEGFR, PDGFR and FGFR
6056 GSK 1363089 Potent inhibitor of MET, VEGFR2, Ron and AXL
2542 Ki 8751 Potent, selective VEGFR-2 inhibitor
7049 Nintedanib Potent VEGFR, PDGFR and FGFR inhibitor
6015 RAF 265 VEGFR-2 and Raf kinase inhibitor
6814 Sorafenib VEGFR-2 and VEGFR-3 inhibitor; also inhibits Raf-1, PDGFR-β, Flt-3 and cKIT
3300 SU 5402 Potent VEGFR and FGFR inhibitor
3037 SU 5416 VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3
3335 SU 6668 VEGFR, PDGFR and FGFR inhibitor
3768 Sunitinib malate Potent VEGFR, PDGFRβ and KIT inhibitor
5680 Vatalanib succinate Potent VEGFR inhibitor; also aromatase inhibitor
5422 XL 184 Potent VEGFR inhibitor; also inhibits other RTKs
2475 ZM 323881 hydrochloride Potent, selective inhibitor of VEGFR-2

주문정보

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS
전체보기

추천제품

관련제품

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS
전체보기

자료

웨비나/Video

TOP

제품 문의

 0.5 ml Elite Pre-stained Protein Ladder (2 x 0.25 ml) PAL-EPL-500 0.5ml 500
Maker
Cat.No.
Product
Size
Qty
Data Sheet
MSDS

로그인

로그인