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Protein Kinase Inhibitors & Activators 이미지

Protein Kinase Inhibitors & Activators

Signal transduction pathways와 complex cellular functions 조절에 관여하는 Protein Kinase Inhibitors와 Activators를 소개합니다.

특징 

 

  • Kinase는 타겟 substrate의 인산화를 촉매하는 효소입니다. 
  • 광범위한 신호전달 pathway를 중재하고 복잡한 세포 기능을 제어하는 500개 이상의 kinase가 알려져 있습니다. 


주요 제품
AGC Group (Protein Kinase A,G,C)
Cat. No. Product  Activity
0741 GF 109203X Protein kinase C inhibitor
4143 GSK 2334470 Highly potent, selective PDPK1 (PDK1) inhibitor
1288 KT 5720 Selective protein kinase A inhibitor
4630 SB 747651A dihydrochloride Potent MSK1 inhibitor; also inhibits other AGC group kinases
4635 SC 79 Akt activator
CAMK Group (calcium/calmodulin signaling)
Cat. No. Product  Activity
5183 ETP 45835 dihydrochloride Mnk1 and Mnk2 inhibitor
5134 MRT 67307 dihydrochloride Salt inducible kinase (SIK) inhibitor; also ULK1 and 2 inhibitor
5177 WZ 4003 Potent and selective NUAK1/2 inhibitor
CK1 Group (Casein Kinase 1)
Cat. No. Product  Activity
2902 D 4476 Selective CK1 inhibitor. Also inhibits TGF-βRI
4281 PF 4800567 hydrochloride Selective casein kinase 1ε inhibitor
CMGC Group (CDK, MAPK, GSK-3, Clks)
Cat. No. Product  Activity
4753 AL 8697 Potent and selective p38α inhibitor
4423 CHIR 99021 Highly selective GSK-3 inhibitor; acts as Wnt activator
5095 DBM 1285 dihydrochloride  p38 MAPK inhibitor; anti-inflammatory
1202 SB 203580 Selective inhibitor of p38 MAPK
1616 SB 216763 Potent, selective GSK-3 inhibitor
5040 SB 706504 p38 MAPK inhibitor
4875 Senexin A Cdk8 inhibitor
3222 TCS JNK 6o Selective JNK inhibitor
STE Group (homologs of yeast sterile 7, sterile 11, sterile 20 kinase)
Cat. No. Product  Activity
4842 BIX 02189 Selective MEK5 and ERK5 inhibitor
4192 PD 0325901 Potent inhibitor of MEK1/2
1144 U0126 Potent, selective inhibitor of MEK1 and 2
TK Group (Tyrosine Kinase) 
Cat. No. Product  Activity
5310 ASP 3026 Potent anaplastic lymphoma kinase (ALK) inhibitor; also potent ACK inhibitor
5077 DDR1-IN-1 dihydrochloride Selective DDR1 inhibitor
4660 KB SRC 4 Potent and selective c-Src inhibitor
5247 NVP ADW 742 ATP-competitive inhibitor of IGF1R
3037 SU 5416 VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3
TKL Group (Tyrosine kinase-like Kinases)
Cat. No. Product  Activity
4126 DMH-1 Selective ALK2 inhibitor
4986 K 02288 Type 1 BMP receptor inhibitor
4745 LIMKi 3 Potent LIM kinase inhibitor; antitumor
4945 ML 347 Potent and selective ALK1 and ALK2 inhibitor

주문정보

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS
AZD 7648 7825 10 mg TOCRIS
AZD 7648 7825 50 mg TOCRIS
RIPK2 inhibitor 1 6603 50 mg TOCRIS
RIPK2 inhibitor 1 6603 10 mg TOCRIS
Ceapin A7 6955 50 mg TOCRIS
Ceapin A7 6955 10 mg TOCRIS
(+/-)-Palmitoylcarnitine chloride (50 mg) 0609 50 mg TOCRIS
1-Naphthyl PP1 (10 mg) 3063 10 mg TOCRIS
1-Naphthyl PP1 (50 mg) 3063 50 mg TOCRIS
2-Deoxy-D-glucose (50 mg) 4515 50 mg TOCRIS
8-Bromo-cAMP, sodium salt (10 mg) 1140 10 mg TOCRIS
8-Bromo-cAMP, sodium salt (50 mg) 1140 50 mg TOCRIS
8-Bromo-cGMP, sodium salt (10 mg) 1089 10 mg TOCRIS
8-Bromo-cGMP, sodium salt (50 mg) 1089 50 mg TOCRIS
A 1070722 (10 mg) 4431 10 mg TOCRIS
A 1070722 (50 mg) 4431 50 mg TOCRIS
A 419259 trihydrochloride (10 mg) 3914 10 mg TOCRIS
A 77-01 (25 MG) 6712 25 mg TOCRIS
A 77-01 (5 MG) 6712 5 mg TOCRIS
A66 (10 mg) 5595 10 mg TOCRIS
A66 (50 mg) 5595 50 mg TOCRIS
ABT 702 dihydrochloride (10 mg) 2372 10 mg TOCRIS
AL 8697 (10 mg) 4753 10 mg TOCRIS
AL 8697 (50 mg) 4753 50 mg TOCRIS
alpha-Mangostin (50 MG) 6856 50 mg TOCRIS
AMG 548 (10 mg) 3920 10 mg TOCRIS
AMG 900 7865 50 mg TOCRIS
AMG 900 7865 10 mg TOCRIS
AMG PERK 44 (10 mg) 5517 10 mg TOCRIS
AMG PERK 44 (50 mg) 5517 50 mg TOCRIS
Amlexanox (50 mg) 4857 50 mg TOCRIS
AP C5 (10 MG) 6626 10 mg TOCRIS
AP C5 (50 MG) 6626 50 mg TOCRIS
ARN 3236 7511 50 mg TOCRIS
ARN 3236 7511 10 mg TOCRIS
AX 15836 (10 mg) 5843 10 mg TOCRIS
AZ 13705339 (10 MG) 6177 10 mg TOCRIS
AZ 13705339 (50 MG) 6177 50 mg TOCRIS
AZ 628 (10 mg) 4836 10 mg TOCRIS
AZ 628 (50 mg) 4836 50 mg TOCRIS
AZ Dyrk1B 33 (10 mg) 5632 10 mg TOCRIS
AZ PFKFB3 26 (10 MG) 5675 10 mg TOCRIS
AZ PFKFB3 26 (50 MG) 5675 50 mg TOCRIS
AZ PFKFB3 67 (10 mg) 5742 10 mg TOCRIS
AZ PFKFB3 67 (50 mg) 5742 50 mg TOCRIS
AZD 1208 (10 MG) 6310 10 mg TOCRIS
AZD 1208 (50 MG) 6310 50 mg TOCRIS
AZD 6482 (10 mg) 4839 10 mg TOCRIS
AZD 6482 (50 mg) 4839 50 mg TOCRIS
AZD 8055 7840 10 mg TOCRIS
전체보기
Maker
TOCRIS
Cat.No.
7825
Product
AZD 7648
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7825
Product
AZD 7648
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6603
Product
RIPK2 inhibitor 1
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6603
Product
RIPK2 inhibitor 1
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6955
Product
Ceapin A7
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6955
Product
Ceapin A7
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
0609
Product
(+/-)-Palmitoylcarnitine chloride (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3063
Product
1-Naphthyl PP1 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3063
Product
1-Naphthyl PP1 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4515
Product
2-Deoxy-D-glucose (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
1140
Product
8-Bromo-cAMP, sodium salt (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
1140
Product
8-Bromo-cAMP, sodium salt (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
1089
Product
8-Bromo-cGMP, sodium salt (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
1089
Product
8-Bromo-cGMP, sodium salt (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4431
Product
A 1070722 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4431
Product
A 1070722 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3914
Product
A 419259 trihydrochloride (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6712
Product
A 77-01 (25 MG)
Size
25 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6712
Product
A 77-01 (5 MG)
Size
5 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5595
Product
A66 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5595
Product
A66 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
2372
Product
ABT 702 dihydrochloride (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4753
Product
AL 8697 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4753
Product
AL 8697 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6856
Product
alpha-Mangostin (50 MG)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3920
Product
AMG 548 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7865
Product
AMG 900
Size
50 mg
Qty
Data Sheet
Maker
TOCRIS
Cat.No.
7865
Product
AMG 900
Size
10 mg
Qty
Data Sheet
Maker
TOCRIS
Cat.No.
5517
Product
AMG PERK 44 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5517
Product
AMG PERK 44 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4857
Product
Amlexanox (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6626
Product
AP C5 (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6626
Product
AP C5 (50 MG)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7511
Product
ARN 3236
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7511
Product
ARN 3236
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5843
Product
AX 15836 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6177
Product
AZ 13705339 (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6177
Product
AZ 13705339 (50 MG)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4836
Product
AZ 628 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4836
Product
AZ 628 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5632
Product
AZ Dyrk1B 33 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5675
Product
AZ PFKFB3 26 (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5675
Product
AZ PFKFB3 26 (50 MG)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5742
Product
AZ PFKFB3 67 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5742
Product
AZ PFKFB3 67 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6310
Product
AZD 1208 (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6310
Product
AZD 1208 (50 MG)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4839
Product
AZD 6482 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4839
Product
AZD 6482 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7840
Product
AZD 8055
Size
10 mg
Qty
Data Sheet
MSDS
전체보기

추천제품

자료

  • Kinases Product Listing

    Kinases Product Listing 이미지

    [TOCRIS]

    Kinome group별로 다양한 protein kinase inhibitors의 정보를 제공합니다.

  • Tocriscreen Compound Libraries Product Listing Brochure

    Tocriscreen Compound Libraries Product Listing Brochure 이미지

    [TOCRIS]

    기존약물의 새로운 용도를 밝힐 수 있는 약물 리퍼포징 및 효과적인 스크리닝을 위한 화합물 라이브러리를 소개합니다.

  • KINOMEscan® Kinase Screening and Profiling Services

    KINOMEscan® Kinase Screening and Profiling Services 이미지

    [EUROFINS DISCOVERY]

    KINOMEscan® Kinase Screening과 Profiling 서비스에 대한 안내입니다.

웨비나/Video

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제품 문의

0.5 ml Elite Pre-stained Protein Ladder (2 x 0.25 ml) PAL-EPL-500 0.5ml 500
Maker
Cat.No.
Product
Size
Qty
Data Sheet
MSDS

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