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제품 상세

Antibody

6.5 - 270 kDa 범위를 커버하는 3가지 컬러 밴드를 포함하며,
최대 100%까지의 transfer 효과를 개런티하는 Prestained protein ladder를 소개합니다.

배경

 

 

  • ​MAPK(Mitogen-Activated Protein Kinase)는 serine기와 threonine기에 phosphorylation 시켜주는 protine kinase family입니다. 증식, 분화, 발달, 변형, 스트레스 반응 및 생존에 중요한 역할을 합니다. 
  • MAPK family는 크게 Erk, JNK/SAPK, p38 MAPK로 나뉩니다. 미토젠, 사이토카인, 성장인자, 스트레스 등 세포외 자극에 의해 MAPK cascade가 활성화됩니다. 활성화된 MAPK는 하위  기질을 인산화하여 신호를 증폭하고 다양한 생물학적 과정을 증폭합니다.

 

 




 

 

주요 제품 

 

 

anti-p38 MAPK antibody (#ARG55258)
Product Description Rabbit Polyclonal antibody recognizes p38 MAPK
Tested Reactivity Hu, Ms, Rat
Tested Application ICC/IF, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name p38 MAPK
Antigen Species Human
Immunogen Recombinant protein of Human MAPK14 (Swiss: Q16539).
Conjugation Un-conjugated
Alternate Names CSBP2; PRKM14; MAX-interacting protein 2; SAPK2A; Stress-activated protein kinase 2a; CSBP1; Mxi2; EC 2.7.11.24; CSBP; SAPK2a; RK; CSPB1; MAPK 14; p38; MAP kinase 14; MAP kinase MXI2; Cytokine suppressive anti-inflammatory drug-binding protein; MAP kinase p38 alpha; Mitogen-activated protein kinase p38 alpha; EXIP; CSAID-binding protein; p38ALPHA; PRKM15; Mitogen-activated protein kinase 14
     
anti-p38 MAPK phospho (Thr180 / Tyr182) antibody (#ARG51850)
Product Description Rabbit Polyclonal antibody recognizes p38 MAPK phospho (Thr180 / Tyr182)
Tested Reactivity Hu, Ms, Rat
Predict Reactivity Cow
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name p38 MAPK
Antigen Species Human
Immunogen Peptide sequence around phosphorylation site of threonine 180 or tyrosine 182 (E-M-T(p)-G-Y(p)-V-A) derived from Human P38 MAPK.
Conjugation Un-conjugated
Alternate Names CSBP2; PRKM14; MAX-interacting protein 2; SAPK2A; Stress-activated protein kinase 2a; CSBP1; Mxi2; EC 2.7.11.24; CSBP; SAPK2a; RK; CSPB1; MAPK 14; p38; MAP kinase 14; MAP kinase MXI2; Cytokine suppressive anti-inflammatory drug-binding protein; MAP kinase p38 alpha; Mitogen-activated protein kinase p38 alpha; EXIP; CSAID-binding protein; p38ALPHA; PRKM15; Mitogen-activated protein kinase 14
     
anti-A RAF antibody (#ARG57359)
Product Description Rabbit Polyclonal antibody recognizes A RAF
Tested Reactivity Hu
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name A RAF
Antigen Species Human
Immunogen Recombinant Protein of Human A-RAF.
Conjugation Un-conjugated
Alternate Names Proto-oncogene A-Raf; ARAF1; Proto-oncogene A-Raf-1; RAFA1; PKS2; Proto-oncogene Pks; A-RAF; EC 2.7.11.1; Serine/threonine-protein kinase A-Raf
     
anti-B Raf antibody (#ARG54698)
Product Description Rabbit Polyclonal antibody recognizes B Raf
Tested Reactivity Hu
Predict Reactivity Ms, Chk
Tested Application FACS, ICC/IF, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Target Name B Raf
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide corresponding to aa. 424-453 of Human B Raf (NP_004324.2).
Conjugation Un-conjugated
Alternate Names BRAF1; v-Raf murine sarcoma viral oncogene homolog B1; Proto-oncogene B-Raf; p94; Serine/threonine-protein kinase B-raf; RAFB1; EC 2.7.11.1; B-RAF1; NS7
     
anti-ERK1 + ERK2 antibody [E31R] (#ARG62350)
Product Description Mouse Monoclonal antibody [E31R] recognizes ERK1 + ERK2
Tested Reactivity Hu, Ms, Rat, Dog
Tested Application ICC/IF, WB
Specificity Recognizes human ERK1 and ERK2 proteins.
Host Mouse
Clonality Monoclonal
Clone E31R
Isotype IgG1
Target Name ERK1 + ERK2
Antigen Species Human
Immunogen Full length recombinant human ERK1 protein.
Conjugation Un-conjugated
Alternate Names MAPK 2; MAPK 1; MAP kinase 2; ERK-2; p41; ERK; MAP kinase 1; PRKM2; PRKM1; EC 2.7.11.24; MAPK2; p40; Extracellular signal-regulated kinase 2; p38; Mitogen-activated protein kinase 2; Mitogen-activated protein kinase 1; ERK2; MAP kinase isoform p42; p42-MAPK; P42MAPK; p41mapk; ERT1
     
anti-ERK1 + ERK2 phospho (Thr202 / Tyr204) antibody (#ARG52277)
Product Description Rabbit Polyclonal antibody recognizes ERK1 + ERK2 phospho (Thr202 / Tyr204)
Tested Reactivity Hu, Ms, Rat, Dog
Predict Reactivity Bov, Chk, NHuPrm, Xenopus laevis, Zfsh
Tested Application ICC/IF, IHC, WB
Specificity Specific for the ~42k - 44k ERK/MAPK phosphorylated at Thr202 and Tyr204 at p44 (ERK1), and Thr185 and Tyr187 at p42 (ERK2). Immunolabeling is blocked by the phosphopeptide used as antigen but not by the corresponding dephosphopeptide. The immunolabeling is completely eliminated by λ-phosphatase.
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name ERK1 + ERK2
Antigen Species Rat
Immunogen KLH-conjugated phosphospecific peptide around Thr202/Tyr204 of Rat ERK1.
Conjugation Un-conjugated
Alternate Names MAPK 2; MAPK 1; MAP kinase 2; ERK-2; p41; ERK; MAP kinase 1; PRKM2; PRKM1; EC 2.7.11.24; MAPK2; p40; Extracellular signal-regulated kinase 2; p38; Mitogen-activated protein kinase 2; Mitogen-activated protein kinase 1; ERK2; MAP kinase isoform p42; p42-MAPK; P42MAPK; p41mapk; ERT1
     
anti-SAPK / JNK antibody (#ARG51218)
Product Description Rabbit Polyclonal antibody recognizes SAPK / JNK
Tested Reactivity Hu, Ms, Rat
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name SAPK / JNK
Antigen Species Human
Immunogen Peptide sequence around aa.181~185 (M-M-T-P-Y) derived from Human SAPK / JNK.
Conjugation Un-conjugated
Alternate Names MAP kinase 9; JNK2BETA; PRKM9; EC 2.7.11.24; c-Jun N-terminal kinase 2; Stress-activated protein kinase 1a; SAPK; Stress-activated protein kinase JNK2; MAPK 9; JNK2; JNK2ALPHA; JNK2A; JNK2B; SAPK1a; JNK-55; Mitogen-activated protein kinase 9; p54a; p54aSAPK

 

 

 

 

 


 


 

주문정보

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제품 문의

0.5 ml Elite Pre-stained Protein Ladder (2 x 0.25 ml) PAL-EPL-500 0.5ml 500
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