고마바이오텍(주)

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제품 상세

Antibody

6.5 - 270 kDa 범위를 커버하는 3가지 컬러 밴드를 포함하며,
최대 100%까지의 transfer 효과를 개런티하는 Prestained protein ladder를 소개합니다.

프린트 제품 문의

dCypher® Nucleosome Panels   


  • 단일 및 combinatorially-modified nucleosome으로 구성되어 있습니다.
  • 4가지 panel 선택이 가능합니다.
  • Binding domain protein assays, Enzyme activity assays, Antibody specificity validation 에 이용됩니다.

 

Cat. No.PanelMononucleosomes 수Expressed histones
16-9001Full 77 unique mononucleosomes 포함two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908, H2B-O60814, H3.1-P68431/H3.2-Q71DI3/H3.3-P84243, H4-P62805
16-9002K-MetStat & OncoStat24 unique mononucleosomes 포함two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908, H2B-O60814, H3.1-P68431/H3.2-Q71DI3/H3.3-P84243, H4-P62805
16-9003K-AcylStat23 unique mononucleosomes 포함two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908, H2B-O60814, H3.1-P68431/H3.2-Q71DI3, H4-P62805
16-9004 R-MetStat 15 unique mononucleosomes 포함two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908, H2B-O60814, H3.1-P68431/H3.2-Q71DI3, H4-P62805

 

     

Recombinant Nucleosome (rNucs™)   


  • PTM이 진행되지 않은 Fully recombinant nucleosome 입니다.
  • Inhibitor testing, enzyme assay등에 이용됩니다.

 

Cat. No. Product
16-0006  Mononucleosomes, Recombinant Human Biotinylated
16-0009  Mononucleosomes, Recombinant Human
16-0023  Mononucleosomes, H3.1 ΔN2, biotinylated 
16-0016  Mononucleosomes (H3.1 ΔN32), Recombinant Human Biotinylated
16-1016  Mononucleosomes (H3.1ΔN32), Recombinant Human
16-0017  Mononucleosomes (H3.3 ΔN32), Recombinant Human Biotinylated
16-1017  Mononucleosomes (H3.3 ΔN32), Recombinant Human
16-0018 Mononucleosomes (H4 ΔN15), Recombinant Human Biotinylated
16-0027 Tailless Nucleosomes, Recombinant Human, Biotinylated
16-0024 Mononucleosomes, Recombinant Human, Desthiobiotinylated

 

  

Oncogenic Nucleosomes (oncoNucs™) 


  • 특정 histone의 아미노산기를 암유발 mutation 시퀀스로 치환한 recombinant nucleosome 입니다.
  • enzyme activity에 있어 mutation의 효과 및 drug/inhibitor 효과를 스터디하는데 유용합니다.

 

Cat. No. Product
16-1031 Nucleosome, Recombinant Human, Acidic Patch Mutant H2BE105A,E113A
16-1030 Nucleosome, Recombinant Human, Acidic Patch Mutant H2AE92K
16-1029 Nucleosome, Recombinant Human, Acidic Patch Mutant H2AE61A
16-0029 Nucleosome, Recombinant Human, Acidic Patch Mutant H2AE61A Biotinylated
16-0030 Nucleosome, Recombinant Human, Acidic Patch Mutant H2AE92K Biotinylated
16-0031 Nucleosome, Recombinant Human, Acidic Patch Mutant H2BE105A,E113A Biotinylated
16-0346 Mononucleosomes (H3.3G34R), Recombinant Human, Biotinylated
16-0349  Mononucleosomes (H3.3K4M), Recombinant Human Biotinylated
16-0350  Mononucleosomes (H3.3K9M), Recombinant Human Biotinylated
16-1323  Mononucleosomes (H3.3 K27M), Recombinant Human Biotinylated
16-0323  Mononucleosomes (H3.3 K27M), Recombinant Human
16-0347  Mononucleosomes (H3.3G34V), Recombinant Human Biotinylated
16-0348  Mononucleosomes (H3.3G34W), Recombinant Human Biotinylated
16-0344 Mononucleosomes (H3.3K36M), Recombinant Human Biotinylated

  

 

Histone Variant Nucleosomes (vNucs™)  


  • Histone varients를 포함하고 있는 recombinant nucleosome 입니다.

 

Cat. No. Product
16-0013  Mononucleosomes (H2AX), Human Recombinant Biotinylated
16-1013  Mononucleosomes (H2AX), Human Recombinant
16-0014  Mononucleosomes (H2AZ.1), Human Recombinant Biotinylated
16-1014  Mononucleosomes (H2AZ.1), Human Recombinant
16-0015  Mononucleosomes (H2AZ.2), Human Recombinant Biotinylated
16-0011  Mononucleosomes (H3.3), Human Recombinant Biotinylated
16-0012 Mononucleosomes (H3.3), Human Recombinant

  

 

Chromatin Remodeling Assay Substrate (EpiDyne™)   


  • In vitro Nucleosome Remodeling (repositioning)을 모니터링 하는데 이용되는 nucleosome 입니다.
  • Histone을 감싸고 있는 DNA의 5'말단을 Cy3로 처리하고, Histone octamer는 Cy5로 라벨링되었습니다.
  • Histone octamer가 재배치 되거나 방출될때 Cy5가 소실되므로 Cy3-Cy5 FRET의 원리를 통해 확인합니다.


Designer Nucleosome (dNucs™)    


  • Histone의 특정한 위치에 이미 acetylation, methylation등의 PTM이 진행된 recombinant nucleosome 입니다.
  • 타겟 enzyme/protein에 대한 substrate로 이용될 수 있습니다.
  • lot-to-lot variation 이 낮아 높은 재현성을 보여줍니다.
  • Free DNA가 포함되지 않아 안정성이 높습니다.
  • Biotinylated, Non-biotinylated dNucs이 있습니다. 

 

Lysine Methylation  

 

Cat. No. Product
16-0321  H3K4me1, biotinylated
16-0334  H3K4me2, biotinylated 
16-1334  H3K4me2, non-biotinylated
16-0316  H3K4me3, biotinylated
16-1316  H3K4me3, non-biotinylated 
16-0325  H3K9me1, biotinylated 
16-0324  H3K9me2, biotinylated 
16-0315  H3K9me3, biotinylated
16-0338  H3K27me1, biotinylated
16-0339  H3K27me2, biotinylated
16-0317  H3K27me3, biotinylated
16-1317  H3K27me3, non-biotinylated 
16-0322  H3K36me1, biotinylated
16-0319  H3K36me2, biotinylated 
16-1319  H3K36me2, non-biotinylated
16-0320  H3K36me3, biotinylated
16-1320  H3K36me3, non-biotinylated 
16-0390  H3.3K36me3, biotinylated 
16-0367  H3K79me1, biotinylated 
16-0368  H3K79me2, biotinylated 
16-0369  H3K79me3, biotinylated
16-0393  H4K12me1, biotinylated 
16-0331  H4K20me1, biotinylated 
16-0332  H4K20me2, biotinylated 
16-0333  H4K20me3, biotinylated
16-1333 H4K20me3, non-biotinylated

  

 

Lysine Acetylation  

 

Cat. No. Product
16-0386  H2BK12ac, biotinylated 
16-0387  H2BK20ac, biotinylated 
16-0342  H3K4ac, biotinylated 
16-0314  H3K9ac, biotinylated 
16-1314  H3K9ac, non-biotinylated 
16-0371  H3K9bu, biotinylated 
16-0351  H3K9cr, biotinylated 
16-0343  H3K14ac, biotinylated 
16-0372  H3K18ac, biotinylated 
16-0373  H3K18bu, biotinylated 
16-0337  H3K18cr, biotinylated 
16-0364  H3K23ac, biotinylated 
16-0365  H3K27ac, biotinylated 
16-1365  H3K27ac, non-biotinylated 
16-0384  H3K27bu, biotinylated 
16-0383  H3K27cr, biotinylated 
16-0385  H3K27ac, S28phos, biotinylated 
16-0378  H3K36ac, biotinylated 
16-0352  H4K5ac, biotinylated 
16-0353  H4K8ac, biotinylated 
16-0312  H4K12ac, biotinylated 
16-0354  H4K16ac, biotinylated 
16-0377  H4K20ac, biotinylated 
16-0376  H2AK5,9,13,15ac, biotinylated 
16-0336  H3K4,9,14,18ac, biotinylated 
16-0335  H3K4me3, K9,14,18ac, biotinylated 
16-0313  H4K5,8,12,16ac, biotinylated 
16-1313  H4K5,8,12,16ac, non-biotinylated 
16-0374 H3K4,9,14,18ac / H4K5,8,12,16ac, biotinylated 

  

 

Arginine Methylation 

 

Cat. No. Product
16-0359  H2AR3me1, biotinylated 
16-0360  H2AR3me2a, biotinylated 
16-0361  H2AR3me2s, biotinylated 
16-0340  H3R2me1, biotinylated 
16-0341  H3R2me2a, biotinylated 
16-0355  H3R2me2s, biotinylated 
16-0379  H3R8me1, biotinylated 
16-0380  H3R8me2a, biotinylated 
16-0381  H3R8me2s, biotinylated 
16-0382  H3R17me1, biotinylated 
16-0375  H3R17me2a, biotinylated 
16-0356  H4R3me1, biotinylated 
16-0357  H4R3me2a, biotinylated 
16-0358 H4R3me2s, biotinylated 

  


Lysine Ubiquitination 

 

Cat. No. Product
16-0020  H2AUb1, biotinylated
16-0363  H2AK119ub, biotinylated
16-0370  H2BK120ub, biotinylated
16-0391 H3K14ub, biotinylated

 

  

Other PTMs 

 

Cat. No. Product
16-0362  H3R2,8,17cit, biotinylated
16-1362  H3R2,8,17cit, non-biotinylated
16-0345  H3S10phos, biotinylated
16-1345  H3S10phos, non-biotinylated
16-0388  H3.1S28phos, biotinylated
16-0389 H3.3S31phos, biotinylated

  

 

Methyl DNA Designer Nucleosomes   

 

Cat. No. Product
18-2044 Nucleosome Assembly 601 Sequence DNA, 199 bp, Biotinylated
16-2045 Mononucleosomes, Recombinant, Symmetrically Methylated 199x601 DNA, Biotinylated
16-2144 Mononucleosomes, Recombinant, 199x601 DNA, Non-biotinylated
16-2044 Mononucleosomes, Recombinant, 199x601 DNA, Biotinylated
16-2043 Mononucleosomes, Recombinant, Hemi-methylated 199x601 DNA, Biotinylated
16-2143 Mononucleosomes, Recombinant, Hemi-methylated 199x601 DNA, Non-biotinylated


 

 

주문정보

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS
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관련제품

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
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제품 문의

 0.5 ml Elite Pre-stained Protein Ladder (2 x 0.25 ml) PAL-EPL-500 0.5ml 500
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