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제품 상세
GLP-1, GIP, GCG 스크리닝 Assay Kit 이미지

GLP-1, GIP, GCG 스크리닝 Assay Kit

비만과 제2형 당뇨병(T2D) 연구 타겟인 GLP-1, GIP, GCG를 타겟으로 하는 cAMP, beta-Arrestin, Receptor internalization assay kit를 제공합니다.

프린트 제품 문의

배경 

 

  • 많은 신흥 펩타이드 치료제는 GLP-1 (글루카곤 유사 펩타이드-1) 및 GIP (위 억제 폴리펩타이드)와 같은 incretin 계열 호르몬에 초점을 맞추고 있으며 효과를 연장하고 효능을 향상시키기 위해 변형되었습니다. 
  • GLP-1R 및 GIPR과 함께 Glucagon 수용체 (GCGR)에 작용하여 시너지 효과를 입증하는 GLP-1-GIP-GCC 삼중 작용제 펩타이드인 Retatrutide(LY3437943, Eli Lilly)의 개발로 인해 혁신약물, 바이오시밀러 및 세가지 수용체를 표적으로 하는 소분자에 초점을 맞춘 임상 개발 프로그램이 증가되고 있습니다. 
  • Eurofins DiscoverX는 이러한 세가지 표적 (GLP-1, GIP, GCG) 및 기타 표적을 겨냥한 다양한 펩타이드 치료제에 맞춰진 포괄적인 분석 kit을 제공합니다. 


주요 제품

cAMP Accumulation Detection Assay Kits
  • Full or partial agonist로서의 치료제 평가
  • GLP-1, GIP, GCGR에서의 drug potency 평가
  • 약물의 정확한 반감기 결정을 위한 Albumin 존재하에서의 potency shift 평가 

 Targets Innovator Qualified Bioassay Kits Target-based Bioassay Kits Stable Cell Line (continuous culture) eXpress™ Assay Kits
 GLP-1R • cAMP Hunter Exenatide Bioassay Kit • cAMP Hunter GLP-1 RA Bioassay Kit* • cAMP Hunter CHO-K1 GLP1R Gs Cell Line • cAMP Hunter eXpress GLP1R CHO-K1 Assays
• cAMP Hunter Semaglutide Bioassay Kit
• cAMP Hunter Liraglutide Bioassay Kit
• cAMP Hunter Tirzepatide (GLP-1 RA) Bioassay Kit
• cAMP Hunter Retatrutide Bioassay Kit *
 GIPR • cAMP Hunter Tirzepatide (GIP RA) Bioassay Kit * • cAMP Hunter GIP RA Bioassay Kit • cAMP Hunter CHO-K1 GIPR Gs Cell Line • cAMP Hunter eXpress GIPR CHO-K1 Assay
• cAMP Hunter Retatrutide Bioassay Kit *
 GCGR • cAMP Hunter Retatrutide (GCG RA) Bioassay Kit * • cAMP Hunter GCG RA Bioassay Kit * • cAMP Hunter CHO-K1 GCGR Gs Cell Line • cAMP Hunter eXpress GCGR CHO-K1 Assay


β-arrestin Recruitment Assay Kits
  • 타겟 receptor에서의 Potency shift와 signal bias 결정
  • b-arrestin recruitment와 native GIP, GLP-1과의 비교


Receptor Internalization Assay Kits
  • Potency의 차이가 GPCR signaling bias에 주는 영향 평가
  • b-arrestin recruitment assay에 대한 보완 분석 


 

* coming soon

주문정보

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS
cAMP Hunter™ eXpress GCGR CHO-K1 GPCR Assay 95-0042E2CP2L 1 kit EUROFINS DISCOVERX
cAMP Hunter™ eXpress GCGR CHO-K1 GPCR Assay 95-0042E2CP2M 1 kit EUROFINS DISCOVERX
cAMP Hunter™ eXpress GIPR CHO-K1 GPCR Assay 95-0146E2CP2M 1 kit EUROFINS DISCOVERX
cAMP Hunter™ eXpress GIPR CHO-K1 GPCR Assay 95-0146E2CP2L 1 kit EUROFINS DISCOVERX
cAMP Hunter™ eXpress GLP1R CHO-K1 GPCR Assay 95-0062E2CP2M 1 kit EUROFINS DISCOVERX
cAMP Hunter™ eXpress GLP1R CHO-K1 GPCR Assay 95-0062E2CP2L 1 kit EUROFINS DISCOVERX
PathHunter® eXpress GCGR CHO-K1 β-Arrestin GPCR Assay 93-0241E2CP0L 1 kit EUROFINS DISCOVERX
PathHunter® eXpress GCGR CHO-K1 β-Arrestin GPCR Assay 93-0241E2CP0M 1 kit EUROFINS DISCOVERX
PathHunter® eXpress GCGR CHO-K1 β-Arrestin-1 GPCR Assay 93-0979E2CP2M 1 kit EUROFINS DISCOVERX
PathHunter® eXpress GCGR CHO-K1 β-Arrestin-1 GPCR Assay 93-0979E2CP2L 1 kit EUROFINS DISCOVERX
PathHunter® eXpress GCGR Total GPCR Internalization Assay 93-0820E1CP0L 1 kit EUROFINS DISCOVERX
PathHunter® eXpress GCGR Total GPCR Internalization Assay 93-0820E1CP0M 1 kit EUROFINS DISCOVERX
PathHunter® eXpress GIPR CHO-K1 β-Arrestin GPCR Assay 93-1095E2CP2M 1 kit EUROFINS DISCOVERX
PathHunter® eXpress GIPR CHO-K1 β-Arrestin GPCR Assay 93-1095E2CP2L 1 kit EUROFINS DISCOVERX
PathHunter® eXpress GLP1R Activated GPCR Internalization Assay 93-0724E3CP0M 1 kit EUROFINS DISCOVERX
PathHunter® eXpress GLP1R Activated GPCR Internalization Assay 93-0724E3CP0L 1 kit EUROFINS DISCOVERX
PathHunter® eXpress GLP1R CHO-K1 β-Arrestin GPCR Assay 93-0300E2CP0M 1 kit EUROFINS DISCOVERX
PathHunter® eXpress GLP1R CHO-K1 β-Arrestin GPCR Assay 93-0300E2CP0L 1 kit EUROFINS DISCOVERX
PathHunter® eXpress GLP1R CHO-K1 β-Arrestin-1 GPCR Assay 93-0914E2CP2L 1 kit EUROFINS DISCOVERX
PathHunter® eXpress GLP1R CHO-K1 β-Arrestin-1 GPCR Assay 93-0914E2CP2M 1 kit EUROFINS DISCOVERX
PathHunter® eXpress GLP1R Total GPCR Internalization Assay 93-1075E3CP5M 1 kit EUROFINS DISCOVERX
PathHunter® eXpress GLP1R Total GPCR Internalization Assay 93-1075E3CP5L 1 kit EUROFINS DISCOVERX
cAMP Hunter™ CHO-K1 GCGR Gs Cell Line 95-0042C2 1 vial EUROFINS DISCOVERX
cAMP Hunter™ CHO-K1 GIPR Gs Cell Line 95-0146C2 1 vial EUROFINS DISCOVERX
cAMP Hunter™ CHO-K1 GLP1R Gs Cell Line 95-0062C2 1 vial EUROFINS DISCOVERX
PathHunter® GCGR Total GPCR Internalization HEK 293 Cell Line 93-0820C1 1 vial EUROFINS DISCOVERX
PathHunter® GLP1R Activated GPCR Internalization U2OS Cell Line 93-0724C3 1 vial EUROFINS DISCOVERX
PathHunter® GLP1R Total GPCR Internalization U2OS Cell Line 93-1075C3 1 vial EUROFINS DISCOVERX
cAMP Hunter™ Exenatide Bioassay Kit 95-0062Y2-00101 1 kit EUROFINS DISCOVERX
cAMP Hunter™ Exenatide Bioassay Kit 95-0062Y2-00102 1 kit EUROFINS DISCOVERX
cAMP Hunter™ GIP RA Bioassay Kit - 10 Plates 95-0146Y2-00205 10 Plates EUROFINS DISCOVERX
cAMP Hunter™ GIP RA Bioassay Kit - 10 Plates No Control 95-0146Y2-00206 10 Plates No Control EUROFINS DISCOVERX
cAMP Hunter™ GIP RA Bioassay Kit - 2 Plates 95-0146Y2-00204 2 Plates EUROFINS DISCOVERX
cAMP Hunter™ Liraglutide Bioassay Kit 95-0062Y2-00100 1 kit EUROFINS DISCOVERX
cAMP Hunter™ Liraglutide Bioassay Kit 95-0062Y2-00099 1 kit EUROFINS DISCOVERX
cAMP Hunter™ Semaglutide Bioassay Kit 95-0062Y2-00176 1 kit EUROFINS DISCOVERX
cAMP Hunter™ Semaglutide Bioassay Kit 95-0062Y2-00175 1 kit EUROFINS DISCOVERX
cAMP Hunter™ Tirzepatide (GLP-1 RA) Bioassay Kit - 10 Plates 95-0062Y2-00199 10 Plates EUROFINS DISCOVERX
cAMP Hunter™ Tirzepatide (GLP-1 RA) Bioassay Kit - 10 Plates No Control 95-0062Y2-00200 10 Plates No Control EUROFINS DISCOVERX
cAMP Hunter™ Tirzepatide (GLP-1 RA) Bioassay Kit - 2 Plates 95-0062Y2-00198 2 Plates EUROFINS DISCOVERX
PathHunter® CHO-K1 GCGR β-Arrestin Cell Line 93-0241C2 1 vial EUROFINS DISCOVERX
PathHunter® CHO-K1 GCGR β-Arrestin-1 Cell Line 93-0979C2 1 vial EUROFINS DISCOVERX
PathHunter® CHO-K1 GIPR β-Arrestin Cell Line 93-1095C2 1 vial EUROFINS DISCOVERX
PathHunter® CHO-K1 GLP1R β-Arrestin Cell Line 93-0300C2 1 vial EUROFINS DISCOVERX
PathHunter® CHO-K1 GLP1R β-Arrestin-1 Cell Line 93-0914C2 1 vial EUROFINS DISCOVERX
PathHunter® GLP1 (7-37) Bioassay Kit 93-0300Y2-00028 1 kit EUROFINS DISCOVERX
PathHunter® GLP1 (7-37) Bioassay Kit 93-0300Y2-00027 1 kit EUROFINS DISCOVERX
전체보기
Maker
EUROFINS DISCOVERX
Cat.No.
95-0042E2CP2L
Product
cAMP Hunter™ eXpress GCGR CHO-K1 GPCR Assay
Size
1 kit
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
95-0042E2CP2M
Product
cAMP Hunter™ eXpress GCGR CHO-K1 GPCR Assay
Size
1 kit
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
95-0146E2CP2M
Product
cAMP Hunter™ eXpress GIPR CHO-K1 GPCR Assay
Size
1 kit
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
95-0146E2CP2L
Product
cAMP Hunter™ eXpress GIPR CHO-K1 GPCR Assay
Size
1 kit
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
95-0062E2CP2M
Product
cAMP Hunter™ eXpress GLP1R CHO-K1 GPCR Assay
Size
1 kit
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
95-0062E2CP2L
Product
cAMP Hunter™ eXpress GLP1R CHO-K1 GPCR Assay
Size
1 kit
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
93-0241E2CP0L
Product
PathHunter® eXpress GCGR CHO-K1 β-Arrestin GPCR Assay
Size
1 kit
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
93-0241E2CP0M
Product
PathHunter® eXpress GCGR CHO-K1 β-Arrestin GPCR Assay
Size
1 kit
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
93-0979E2CP2M
Product
PathHunter® eXpress GCGR CHO-K1 β-Arrestin-1 GPCR Assay
Size
1 kit
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
93-0979E2CP2L
Product
PathHunter® eXpress GCGR CHO-K1 β-Arrestin-1 GPCR Assay
Size
1 kit
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
93-0820E1CP0L
Product
PathHunter® eXpress GCGR Total GPCR Internalization Assay
Size
1 kit
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
93-0820E1CP0M
Product
PathHunter® eXpress GCGR Total GPCR Internalization Assay
Size
1 kit
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
93-1095E2CP2M
Product
PathHunter® eXpress GIPR CHO-K1 β-Arrestin GPCR Assay
Size
1 kit
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
93-1095E2CP2L
Product
PathHunter® eXpress GIPR CHO-K1 β-Arrestin GPCR Assay
Size
1 kit
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
93-0724E3CP0M
Product
PathHunter® eXpress GLP1R Activated GPCR Internalization Assay
Size
1 kit
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
93-0724E3CP0L
Product
PathHunter® eXpress GLP1R Activated GPCR Internalization Assay
Size
1 kit
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
93-0300E2CP0M
Product
PathHunter® eXpress GLP1R CHO-K1 β-Arrestin GPCR Assay
Size
1 kit
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
93-0300E2CP0L
Product
PathHunter® eXpress GLP1R CHO-K1 β-Arrestin GPCR Assay
Size
1 kit
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
93-0914E2CP2L
Product
PathHunter® eXpress GLP1R CHO-K1 β-Arrestin-1 GPCR Assay
Size
1 kit
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
93-0914E2CP2M
Product
PathHunter® eXpress GLP1R CHO-K1 β-Arrestin-1 GPCR Assay
Size
1 kit
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
93-1075E3CP5M
Product
PathHunter® eXpress GLP1R Total GPCR Internalization Assay
Size
1 kit
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
93-1075E3CP5L
Product
PathHunter® eXpress GLP1R Total GPCR Internalization Assay
Size
1 kit
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
95-0042C2
Product
cAMP Hunter™ CHO-K1 GCGR Gs Cell Line
Size
1 vial
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
95-0146C2
Product
cAMP Hunter™ CHO-K1 GIPR Gs Cell Line
Size
1 vial
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
95-0062C2
Product
cAMP Hunter™ CHO-K1 GLP1R Gs Cell Line
Size
1 vial
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
93-0820C1
Product
PathHunter® GCGR Total GPCR Internalization HEK 293 Cell Line
Size
1 vial
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
93-0724C3
Product
PathHunter® GLP1R Activated GPCR Internalization U2OS Cell Line
Size
1 vial
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
93-1075C3
Product
PathHunter® GLP1R Total GPCR Internalization U2OS Cell Line
Size
1 vial
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
95-0062Y2-00101
Product
cAMP Hunter™ Exenatide Bioassay Kit
Size
1 kit
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
95-0062Y2-00102
Product
cAMP Hunter™ Exenatide Bioassay Kit
Size
1 kit
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
95-0146Y2-00205
Product
cAMP Hunter™ GIP RA Bioassay Kit - 10 Plates
Size
10 Plates
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
95-0146Y2-00206
Product
cAMP Hunter™ GIP RA Bioassay Kit - 10 Plates No Control
Size
10 Plates No Control
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
95-0146Y2-00204
Product
cAMP Hunter™ GIP RA Bioassay Kit - 2 Plates
Size
2 Plates
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
95-0062Y2-00100
Product
cAMP Hunter™ Liraglutide Bioassay Kit
Size
1 kit
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
95-0062Y2-00099
Product
cAMP Hunter™ Liraglutide Bioassay Kit
Size
1 kit
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
95-0062Y2-00176
Product
cAMP Hunter™ Semaglutide Bioassay Kit
Size
1 kit
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
95-0062Y2-00175
Product
cAMP Hunter™ Semaglutide Bioassay Kit
Size
1 kit
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
95-0062Y2-00199
Product
cAMP Hunter™ Tirzepatide (GLP-1 RA) Bioassay Kit - 10 Plates
Size
10 Plates
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
95-0062Y2-00200
Product
cAMP Hunter™ Tirzepatide (GLP-1 RA) Bioassay Kit - 10 Plates No Control
Size
10 Plates No Control
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
95-0062Y2-00198
Product
cAMP Hunter™ Tirzepatide (GLP-1 RA) Bioassay Kit - 2 Plates
Size
2 Plates
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
93-0241C2
Product
PathHunter® CHO-K1 GCGR β-Arrestin Cell Line
Size
1 vial
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
93-0979C2
Product
PathHunter® CHO-K1 GCGR β-Arrestin-1 Cell Line
Size
1 vial
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
93-1095C2
Product
PathHunter® CHO-K1 GIPR β-Arrestin Cell Line
Size
1 vial
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
93-0300C2
Product
PathHunter® CHO-K1 GLP1R β-Arrestin Cell Line
Size
1 vial
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
93-0914C2
Product
PathHunter® CHO-K1 GLP1R β-Arrestin-1 Cell Line
Size
1 vial
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
93-0300Y2-00028
Product
PathHunter® GLP1 (7-37) Bioassay Kit
Size
1 kit
Qty
Data Sheet
Maker
EUROFINS DISCOVERX
Cat.No.
93-0300Y2-00027
Product
PathHunter® GLP1 (7-37) Bioassay Kit
Size
1 kit
Qty
Data Sheet
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