Cat. No. |
Product |
Activity |
7044 |
(±)-α-Lipoic
acid |
Maintains
function of HSCs in culture; also antioxidant |
4027 |
16,16-Dimethyl Prostaglandin E2 |
Regulates HSC development |
3979 |
Alexidine dihydrochloride |
Preserves functional hematopoietic stem cells ex vivo; also
inhibitor of PTPMT1 |
3299 |
AMD 3100 octahydrochloride |
Promotes HSCs mobilization and expansion |
3194 |
BIO |
Promotes HSC proliferation; also highly selective GSK-3
inhibitor; acts as Wnt activator |
5051 |
BIO 5192 |
Promotes HSCs and progenitor mobilization; also highly potent
and selective inhibitor of integrin α4β1 (VLA-4) |
6047 |
BOP |
Promotes HSCs mobilization; also α9β1/α4β1 integrin inhibitor |
6996 |
BOP-JF549 |
Yellow fluorescent dual α9β1/α4β1 integrin inhibitor comprising
BOP conjugated to Janelia Fluor® 549 |
6997 |
BOP-JF646 |
Red fluorescent dual α9β1/α4β1 integrin inhibitor comprising BOP
conjugated to Janelia Fluor® 646 |
7153 |
BRD 0539 |
Cell permeable and reversible Cas9 inhibitor |
1231 |
Brefeldin A |
Enhances CRISPR-mediated HDR efficiency; also disrupts protein
translocation to Golgi |
5050 |
CASIN |
Induces HSC mobilization; also Cdc42 inhibitor; restores cell
polarity |
3858 |
CH 223191 |
Promotes HSCs expansion in vitro; also potent aryl hydrocarbon
receptor (AhR) antagonist |
4423 |
CHIR 99021 |
Promotes HSC proliferation; also highly selective GSK-3
inhibitor; acts as Wnt activator |
5331 |
CPI 203 |
Promotes HSC expansion; also BET Bromodomain inhibitor |
5702 |
DiD perchlorate |
HSC stain; also lipophilic fluorescent reagent |
6019 |
Diprotin A |
Enhances HSCs viability after harvesting; also dipeptidyl
peptidase IV (DPP-IV) inhibitor |
5304 |
FICZ |
Facilitates hPSC to HSC manufacture in vitro; also aryl
hydrocarbon receptor (AhR) agonist; |
1508 |
GW 9662 |
Promotes HSCs expansion; increases HSCs engraftment; also PPARγ
antagonist |
4840 |
KU 0060648 |
Enhances HDR efficiency and attenuates NHEJ frequency; also dual
DNA-PK and PI 3-K inhibitor |
2197 |
L-755,507 |
Enhances CRISPR-mediated HDR efficiency; also very potent and
selective β3 partial agonist |
6618 |
MB 05032 |
Promotes HSCs expansion; also potent FBPase inhibitor |
5619 |
N-Acetylcysteine amide |
Maintains HSC function in culture; also GSH precursor;
antioxidant |
4106 |
Nicotinamide |
Promotes proliferation and expansion of HSC in vitro; also PARP1
inhibitor |
2828 |
NU 7026 |
Improves HDR-mediated editing in HSCs; also selective DNA-PK
inhibitor |
2296 |
Prostaglandin E2 |
Promotes HSCs expansion; increases HSCs engraftment |
4181 |
Ro 3306 |
Improves HDR-mediated editing in HSCs; also Cdk1 inhibitor |
1202 |
SB 203580 |
Promotes ex vivo expansion of HSC; also p38 MAPK inhibitor |
1614 |
SB 431542 |
Promotes HSCs proliferation; also inhibitor of TGF-βRI, ALK4 and
ALK7 |
5342 |
SCR7 pyrazine |
Enhances HDR efficiency |
3784 |
Sildenafil citrate |
Promotes HSCs mobilization |
7086 |
StemRegenin 1 |
Promotes HSC expansion and engraftment; also aryl hydrocarbon
receptor (AhR) antagonist |
5759 |
SW 033291 |
Promotes HSCs expansion and engraftment; also high affinity
15-PGDH inhibitor |
3082 |
Tempol |
Maintains HSC function in culture; also superoxide scavenger;
Antioxidant |
3114 |
Troglitazone |
Inhibits cell growth of hematopoietic cell lines; also selective
PPARγ agonist; antidiabetic agent |
6002 |
Trolox |
Maintains HSC function in culture; also antioxidant E
derivative; Antioxidant |
5493 |
XL 413 hydrochloride |
Improves HDR-mediated editing in HSCs; also potent and selective
Cdc7 inhibitor |