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제품 상세
다발성 경화증 연구 | Multiple Sclerosis 항체 이미지

다발성 경화증 연구 | Multiple Sclerosis 항체

다발성 경화증(Multiple Sclerosis, MS) 연구에 이용되는 항체를 소개합니다.

배경 

 

중추신경계의 신경염증성 및 탈수초성 질환인 다발성 경화증(MS)은 젊은 성인의 비외상성 신경 장애의 주요 원인입니다. 자가 면역 반응과 탈수초를 감소시키는 것이 다발성 경화증을 치료하는 일반적인 방법입니다. 최근 Nature지에 발표된 Iram et al.의 보고서에 따르면, FGF17이 oligodendrocyte progenitor cell(OPC)의 증식과 분화를 유도하여 기억력을 향상시킵니다. 이 발견은 FGF17을 사용한 수초 복구에 의한 다발성 경화증의 치료 전략에 대한 새로운 통찰력을 제공합니다.

 

 

  

종류

  

FGF17 recombinant protein (Active) (His-tagged, N-ter) (#ARG70123)
Product Description E. coli expressed, His-tagged (N-ter) Active Human FGF17 recombinant protein
Tested Reactivity Hu, Ms
Tested Application SDS-PAGE
Target Name FGF17
Species Human
A.A. Sequence Human FGF17 sequence: TQGEN HPSPN FNQYV RDQGA MTDQL SRRQI REYQL YSRTS GKHVQ VTGRR ISATA EDGNK FAKLI VETDT FGSRV RIKGA ESEKY ICMNK RGKLI GKPSG KSKDC VFTEI VLENN YTAFQ NARHE GWFMA FTRQG RPRQA SRSRQ NQREA HFIKR LYQGQ LPFPN HAEKQ KQFEF VGSAP TRRTK RTRRP QPLT with polyhistidine tag at the N-terminus.
Expression System E. coli
Activity Active
Activity Note Determined by its ability to induce 3T3 cells proliferation. The ED50 for this effect is < 5 ng/ml. The specific activity of recombinant human FGF-17 is > 2 x 10^5 IU/mg
Alternate Names FGF-17; HH20; FGF-13; Fibroblast growth factor 17
     
  anti-FGF17 antibody (#ARG43722)
Product Description Rabbit Polyclonal antibody recognizes FGF17
Tested Reactivity Hu, Ms
Predict Reactivity Rat
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name FGF17
Antigen Species Human
Immunogen Recombinant fusion protein within aa. 20-190 of Human FGF17.
Conjugation Un-conjugated
Protein Full Name Fibroblast growth factor 17
Alternate Names FGF-17; HH20; FGF-13; Fibroblast growth factor 17
     
  anti-NG2 / Chondroitin sulfate proteoglycan 4 antibody (#ARG59471)
Product Description Rabbit Polyclonal antibody recognizes NG2 / Chondroitin sulfate proteoglycan 4
Tested Reactivity Hu, Ms, Rat
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name NG2 / Chondroitin sulfate proteoglycan 4
Antigen Species Human
Immunogen Synthetic peptide derived from Human NG2 / Chondroitin sulfate proteoglycan 4.
Conjugation Un-conjugated
Alternate Names HMW-MAA; MCSPG; Chondroitin sulfate proteoglycan NG2; MCSP; Chondroitin sulfate proteoglycan 4; MSK16; NG2; Melanoma chondroitin sulfate proteoglycan; MEL-CSPG; Melanoma-associated chondroitin sulfate proteoglycan
     
  anti-CNPase antibody (#ARG10754)
Product Description Chicken Polyclonal antibody to CNP
Tested Reactivity Hu, Ms, Rat, Cow
Tested Application ICC/IF, IHC-Fr, WB
Host Chicken
Clonality Polyclonal
Isotype IgY
Target Name CNPase
Antigen Species Human
Immunogen Full length Human recombinant protein
Conjugation Un-conjugated
Alternate Names CNPase; 2',3'-cyclic-nucleotide 3'-phosphodiesterase; CNP1; CNP; EC 3.1.4.37
     
  anti-Myelin Basic Protein antibody [7D2] (#ARG10722)
Product Description Mouse Monoclonal antibody [7D2] recognizes Myelin Basic Protein
Tested Reactivity Hu, Ms, Rat, Cow, Hrs, Pig
Predict Reactivity Chk
Tested Application ICC/IF, IHC-Fr, WB
Host Mouse
Clonality Monoclonal
Clone 7D2
Isotype IgG1
Target Name Myelin Basic Protein
Antigen Species Cow
Immunogen Purified myelin basic protein isolated from cow nerve.
Conjugation Un-conjugated
Alternate Names Myelin A1 protein; MBP; Myelin membrane encephalitogenic protein; Myelin basic protein
     
  anti-MOG / Myelin oligodendrocyte glycoprotein antibody (#ARG41772)
Product Description Rabbit Polyclonal antibody recognizes MOG / Myelin oligodendrocyte glycoprotein
Tested Reactivity Hu, Ms, Rat
Tested Application FACS, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name MOG / Myelin oligodendrocyte glycoprotein
Antigen Species Human
Immunogen Synthetic peptide corresponding to a sequence of Human MOG / Myelin oligodendrocyte glycoprotein. (RVVHLYRNGKDQDGDQAPEYRGRTELLKDAIGEGK)
Conjugation Un-conjugated
Alternate Names BTNL11; BTN6; NRCLP7; MOGIG2; Myelin-oligodendrocyte glycoprotein

 

 

 

주문정보

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS
anti-CNPase antibody ARG10754 50 ul ARIGO
anti-MOG / Myelin oligodendrocyte glycoprotein antibody ARG41772 50 ug ARIGO
anti-Myelin Basic Protein antibody [7D2] ARG10722 50 ul ARIGO
anti-NG2 / Chondroitin sulfate proteoglycan 4 antibody ARG59471 100 ul ARIGO
Human FGF17 recombinant protein (Active) (His-tagged, N-ter) ARG70123 20 ug ARIGO
Human FGF17 recombinant protein (Active) (His-tagged, N-ter) ARG70123 100 ug ARIGO
Maker
ARIGO
Cat.No.
ARG10754
Product
anti-CNPase antibody
Size
50 ul
Qty
Data Sheet
Maker
ARIGO
Cat.No.
ARG41772
Product
anti-MOG / Myelin oligodendrocyte glycoprotein antibody
Size
50 ug
Qty
Data Sheet
Maker
ARIGO
Cat.No.
ARG10722
Product
anti-Myelin Basic Protein antibody [7D2]
Size
50 ul
Qty
Data Sheet
Maker
ARIGO
Cat.No.
ARG59471
Product
anti-NG2 / Chondroitin sulfate proteoglycan 4 antibody
Size
100 ul
Qty
Data Sheet
Maker
ARIGO
Cat.No.
ARG70123
Product
Human FGF17 recombinant protein (Active) (His-tagged, N-ter)
Size
20 ug
Qty
Data Sheet
Maker
ARIGO
Cat.No.
ARG70123
Product
Human FGF17 recombinant protein (Active) (His-tagged, N-ter)
Size
100 ug
Qty
Data Sheet

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제품 문의

0.5 ml Elite Pre-stained Protein Ladder (2 x 0.25 ml) PAL-EPL-500 0.5ml 500
Maker
Cat.No.
Product
Size
Qty
Data Sheet
MSDS

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