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SARS-CoV-2 Pseudoviruses 이미지

SARS-CoV-2 Pseudoviruses

SARS-CoV-2 Pseudovirus는 SARS-CoV-2 spike 단백질을 갖는 모방 바이러스로 코로나 치료제 및 COVID-19 백신 개발에 유용한 도구입니다.

특 징

 

 

  • SARS-CoV-2 Pseudovirus는 SARS-CoV-2 spike 단백질을 갖고 있는 HIV 기반 바이러스로, SARS-CoV-2의 효과를 모방하면서 복제기능은 제거된 pseudovirus 입니다. 
  • Firefly luciferase reporter의 발현을 통해 감염 여부를 확인할 수 있습니다. 
  • ACE2를 발현하는 cell을 효과적으로 감염시키며, spike protein과 ACE2 상호작용 억제제를 스크리닝하고 중화항체 역가를 결정하는데 사용할 수 있습니다.
  • 또한 COVID-19 백신 개발에도 유용하게 이용됩니다. 


주요 제품

 

SARS-CoV-2 WT Pseudovirus

  • CATALOG NUMBER: 95-200
  • Tested Applications: Neut, Viral Infection
  • Size: 1.0 mL (0.5mL X 2 vials)
  • SPECIES: SARS-CoV-2 (COVID-19) Spike pseudovirus
  • SOURCE SPECIES: HEK293 cells
  • RECOMBINANT PROTEIN SEQUENCE: SARS-CoV-2 Spike Met 1 - Cys 1255
  • TESTED APPLICATIONS: Neut, Viral Infection
  • Reporter: Firefly luciferase
  • PHYSICAL STATE: Liquid
  • BUFFER: DMEM/10% FBS
  • Size: 1.0 mL (0.5mL X 2 vials) for two 96-well plates

 

SARS-CoV-2-WT-Pseudovirus-95-200



SARS-CoV-2 Omicron BA.1 Variant Pseudovirus

  • CATALOG NUMBER: 95-201
  • Tested Applications: Neut, Viral Infection
  • Size: 1.0 mL (0.5mL X 2 vials)
  • SPECIES: SARS-CoV-2 (COVID-19) Spike pseudovirus
  • SOURCE SPECIES: HEK293 cells
  • RECOMBINANT PROTEIN SEQUENCE: Omicron Variant Spike BA.1 Met 1 - Cys 1255 (A67V, HV69-70del, T95I, G142D, VYY143-145del, N211del, L212I, ins214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H, N764K, D796Y, N856K, Q954H, N969K, L981F)
  • TESTED APPLICATIONS: Neut, Viral Infection
  • Reporter: Firefly luciferase
  • PHYSICAL STATE: Liquid
  • BUFFER: DMEM/10% FBS
  • Size: 1.0 mL (0.5mL X 2 vials) for two 96-well plates

SARS-CoV-2-omicron-BA.1-Variant-Pseudovirus-95-201



SARS-CoV-2 Omicron BA.2 Variant Pseudovirus

  • CATALOG NUMBER: 95-202
  • Tested Applications: Neut, Viral Infection
  • Size: 1.0 mL (0.5mL X 2 vials)
  • SPECIES: SARS-CoV-2 (COVID-19) Spike pseudovirus
  • SOURCE SPECIES: HEK293 cells
  • RECOMBINANT PROTEIN SEQUENCE: Omicron Variant Spike BA.2 Met 1 - Cys 1251 (T19I, LPP24-26del, A27S, G142D, V213G, G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K)
  • TESTED APPLICATIONS: Neut, Viral Infection
  • Reporter: Firefly luciferase
  • PHYSICAL STATE: Liquid
  • BUFFER: DMEM/10% FBS
  • Size: 1.0 mL (0.5mL X 2 vials) for two 96-well plates


SARS-CoV-2-omicron-BA.2-Variant-Pseudovirus-95-202



SARS-CoV-2 Delta Variant Pseudovirus

  • CATALOG NUMBER: 95-203
  • Tested Applications: Neut, Viral Infection
  • Size: 1.0 mL (0.5mL X 2 vials)
  • SPECIES: SARS-CoV-2 (COVID-19) Spike pseudovirus
  • SOURCE SPECIES: HEK293 cells
  • RECOMBINANT PROTEIN SEQUENCE: Delta Variant Spike Met 1 - Cys 1252 (T19R, T95I, G142D, EF156-157del, R158G, L452R, T478K, D614G, P681R, D950N)
  • TESTED APPLICATIONS: Neut, Viral Infection
  • Reporter: Firefly luciferase
  • PHYSICAL STATE: Liquid
  • BUFFER: DMEM/10% FBS
  • Size: 1.0 mL (0.5mL X 2 vials) for two 96-well plates

SARS-CoV-2-omicron-delta-Variant-Pseudovirus-95-203

 

 

SARS-CoV-1 Pseudovirus

  

  • CATALOG NUMBER: 95-204
  • Tested Applications: Neut, Viral Infection
  • Size: 1.0 mL (0.5mL X 2 vials)
  • SPECIES: SARS-CoV-2 (COVID-19) Spike pseudovirus
  • SOURCE SPECIES: HEK293 cells
  • RECOMBINANT PROTEIN SEQUENCE: SARS-CoV-1 Spike Met 1 - Cys 1236
  • TESTED APPLICATIONS: Neut, Viral Infection
  • PHYSICAL STATE: Liquid
  • BUFFER: DMEM/10% FBS
  • Size: 1.0 mL (0.5mL X 2 vials) for two 96-well plates

 

 

 

주의사항

 

 

  1. BSL-2 이상의 시설에서 사용해야 합니다.
  2. 최소 0.3 x 10^6 RLU/well로 96well plate 기준 1 reaction당 5ul를 이용합니다.
  3. Psudovirus titer 보장을 위해 반복된 동결과 해동을 피해야 합니다.

 

 

 

주문정보

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS
SARS-CoV-1 Pseudovirus 95-204 1ml PROSCI
SARS-CoV-2 Delta Variant Pseudovirus 95-203 1ml PROSCI
SARS-CoV-2 Omicron BA.1 Variant Pseudovirus 95-201 1ml PROSCI
SARS-CoV-2 Omicron BA.2 Variant Pseudovirus 95-202 1ml PROSCI
SARS-CoV-2 WT Pseudovirus 95-200 1ml PROSCI
Maker
PROSCI
Cat.No.
95-204
Product
SARS-CoV-1 Pseudovirus
Size
1ml
Qty
Data Sheet
Maker
PROSCI
Cat.No.
95-203
Product
SARS-CoV-2 Delta Variant Pseudovirus
Size
1ml
Qty
Data Sheet
Maker
PROSCI
Cat.No.
95-201
Product
SARS-CoV-2 Omicron BA.1 Variant Pseudovirus
Size
1ml
Qty
Data Sheet
Maker
PROSCI
Cat.No.
95-202
Product
SARS-CoV-2 Omicron BA.2 Variant Pseudovirus
Size
1ml
Qty
Data Sheet
Maker
PROSCI
Cat.No.
95-200
Product
SARS-CoV-2 WT Pseudovirus
Size
1ml
Qty
Data Sheet

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0.5 ml Elite Pre-stained Protein Ladder (2 x 0.25 ml) PAL-EPL-500 0.5ml 500
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Cat.No.
Product
Size
Qty
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MSDS

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