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세포부착분자 | Cell Adhesion Molecules Inhibitors 이미지

세포부착분자 | Cell Adhesion Molecules Inhibitors

BMS 688521, C26-A6, GLPG 0187, RGD peptide, Surfen등 세포부착분자 (CAMs) Inhibitor를 제공합니다.

특징 

 

  • 세포 외 기질(ECM, Extracellualr matrix)은 세포가 존재할 수 있는 물리적인 미세환경을 제공합니다. 세포가 고정할 수 있는 기질을 제공하고, 조직의 스캐폴드에 주요한 역할을 하고, 배아의 발달과 상처 복구 과정 중의 세포 이동을 안내하고, 조직의 형태를 형성하는 데 중요한 역할을 합니다. 세포 외 기질은 궁극적으로 세포 증식, 분화 및 사멸에 영향을 미치는 환경 신호를 세포에 전달하는 역할도 합니다.
  • ECM은 proteoglycan (세포 완충 역할), 불용성 collagen 섬유 (강도와 탄력 제공), 용해성 다중 접착 ECM 단백질 (fibronectin, laminin / proteoglycan과 collagen 섬유를 세포 표면 수용체에 결합)으로 구성됩니다.  
  • 세포 접착 분자(Cell adhesion molecules, CAMs)는 세포-세포와 세포-ECM 결합에 관여합니다. CAM은 integrain, cadherin, selectin, immunoglobulin superfamily로 구분됩니다. CAM은 세포 증식, 분화, 운동성, 수송, 세포사멸 및 조직 구조에 역할을 합니다.

  

 

주요 제품 

 

Cat. No. Product Activity
2524 A 205804 Selective inhibitor of E-selectin and ICAM-1 expression
4228 A 286982 Potent inhibitor of the LFA-1/ICAM-1 interaction
1845 Ac2-26 Annexin/lipocortin 1-mimetic; inhibits leukocyte extravasation
3910 BIO 1211 Selective α4β1 (VLA-4) inhibitor
5051 BIO 5192 Highly potent and selective inhibitor of integrin α4β1
4776 BIRT 377 Potent negative allosteric modulator of LFA-1
4970 BMS 688521 Potent inhibitor of the LFA-1/ICAM-1 interaction
6047 BOP Dual α9β1/α4β1 integrin inhibitor; preferentially mobilizes HSCs
4724 BTT 3033 Selective inhibitor of integrin α2β1
7692 C26-A6 Disrupts MTDH and SND1 interaction, enhances immune surveillance
5870 Cilengitide Potent and selective inhibitor of integrins αvβ3 and αvβ5
3202 Echistatin, α1 isoform Integrin αVβ3 and glycoprotein IIb/IIIa (integrin αIIbβ3) inhibitor
7059 GLPG 0187 Potent αv integrin inhibitor
1263 GR 144053 trihydrochloride Glycoprotein IIb/IIIa (integrin αIIbβ3) antagonist. Antithrombotic
2812 Heparin sodium salt Anticoagulant
2748 KF 38789 Selective inhibitor of P-selectin-mediated cell adhesion
4577 LDV FITC Fluorescent ligand for α4β1 (VLA-4)
4664 Obtustatin Potent and selective α1β1 inhibitor
2710 OGT 2115 Heparanase inhibitor. Antiangiogenic
5760 P-3FAX-Neu5Ac Sialic acid analog; reduces binding of E- and P-selectin
7723 RGD peptide Minimal recognition sequence for integrin binding; potent integrin inhibitor
3498 RGDS peptide Integrin binding sequence; inhibits integrin receptor function
6634 Surfen Heparin sulfate antagonist
4527 TC-I 15 Potent α2β1 inhibitor; displays antithrombotic activity in vivo
3900 TCS 2314 α4β1 (VLA-4) antagonist
6856 α-Mangostin Modulation of cadherin expression; anticarcinogenic

 

주문정보

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS
A 205804 (10 mg) 2524 10 mg TOCRIS
A 286982 (10 mg) 4228 10 mg TOCRIS
Ac2-26 (500 ug) 1845 500 ug TOCRIS
Ac2-26 (Scrambled) 8094 500 µg TOCRIS
alpha-Mangostin (10 MG) 6856 10 mg TOCRIS
BIRT 377 (10 mg) 4776 10 mg TOCRIS
BMS 688521 (10 MG) 4970 10 mg TOCRIS
BOP (10 MG) 6047 10 mg TOCRIS
BTT 3033 (10 mg) 4724 10 mg TOCRIS
C26-A6 7692 10 mg TOCRIS
C26-A6 7692 50 mg TOCRIS
Cilengitide (10 mg) 5870 10 mg TOCRIS
Defactinib 7305 25 mg TOCRIS
Echistatin, a1 isoform (100 ug) 3202 100 ug TOCRIS
FAK Inhibitor 14 (10 mg) 3414 10 mg TOCRIS
Fasudil hydrochloride (10 mg) 0541 10 mg TOCRIS
GLPG 0187 (10 MG) 7059 10 mg TOCRIS
Glycyl-H-1152 dihydrochloride (1 mg) 2485 1 mg TOCRIS
GR 144053 trihydrochloride (10 mg) 1263 10 mg TOCRIS
GSK 269962 (10 mg) 4009 10 mg TOCRIS
GSK 429286 (1 mg) 3726 1 mg TOCRIS
H 1152 dihydrochloride (1 mg) 2414 1 mg TOCRIS
Heparin sodium salt (100 mg) 2812 100 mg TOCRIS
KF 38789 (10 mg) 2748 10 mg TOCRIS
OXA 06 dihydrochloride (10 mg) 5182 10 mg TOCRIS
P-3FAX-Neu5Ac (10 mg) 5760 10 mg TOCRIS
PF 431396 (10 mg) 4278 10 mg TOCRIS
PF 573228 (10 mg) 3239 10 mg TOCRIS
PND 1186 (10 MG) 6891 10 mg TOCRIS
RGDS peptide (10 mg) 3498 10 mg TOCRIS
RKI 1447 dihydrochloride (10 mg) 5061 10 mg TOCRIS
SB 772077B dihydrochloride (10 mg) 4118 10 mg TOCRIS
SR 3677 dihydrochloride (10 mg) 3667 10 mg TOCRIS
TC-I 15 (10 mg) 4527 10 mg TOCRIS
TC-S 7001 (1 mg) 4961 1 mg TOCRIS
TCS 2314 (10 mg) 3900 10 mg TOCRIS
전체보기
Maker
TOCRIS
Cat.No.
2524
Product
A 205804 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4228
Product
A 286982 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
1845
Product
Ac2-26 (500 ug)
Size
500 ug
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
8094
Product
Ac2-26 (Scrambled)
Size
500 µg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6856
Product
alpha-Mangostin (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4776
Product
BIRT 377 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4970
Product
BMS 688521 (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6047
Product
BOP (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4724
Product
BTT 3033 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7692
Product
C26-A6
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7692
Product
C26-A6
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5870
Product
Cilengitide (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7305
Product
Defactinib
Size
25 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3202
Product
Echistatin, a1 isoform (100 ug)
Size
100 ug
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3414
Product
FAK Inhibitor 14 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
0541
Product
Fasudil hydrochloride (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7059
Product
GLPG 0187 (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
2485
Product
Glycyl-H-1152 dihydrochloride (1 mg)
Size
1 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
1263
Product
GR 144053 trihydrochloride (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4009
Product
GSK 269962 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3726
Product
GSK 429286 (1 mg)
Size
1 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
2414
Product
H 1152 dihydrochloride (1 mg)
Size
1 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
2812
Product
Heparin sodium salt (100 mg)
Size
100 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
2748
Product
KF 38789 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5182
Product
OXA 06 dihydrochloride (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5760
Product
P-3FAX-Neu5Ac (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4278
Product
PF 431396 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3239
Product
PF 573228 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6891
Product
PND 1186 (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3498
Product
RGDS peptide (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5061
Product
RKI 1447 dihydrochloride (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4118
Product
SB 772077B dihydrochloride (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3667
Product
SR 3677 dihydrochloride (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4527
Product
TC-I 15 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4961
Product
TC-S 7001 (1 mg)
Size
1 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3900
Product
TCS 2314 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
전체보기

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0.5 ml Elite Pre-stained Protein Ladder (2 x 0.25 ml) PAL-EPL-500 0.5ml 500
Maker
Cat.No.
Product
Size
Qty
Data Sheet
MSDS

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