| Actin Inhibitors |
|
| Cat. No. |
Product |
Activity |
| 3950 |
CK 666 |
Arp2/3 inhibitor; inhibits actin polymerization |
| 5474 |
Cytochalasin B |
Inhibitor of actin polymerization |
| 1233 |
Cytochalasin D |
Disrupts actin filament function |
| 2792 |
Jasplakinolide |
Stabilizes F-actin; promotes actin polymerization |
| 3973 |
Latrunculin A |
Inhibitor of actin assembly and polymerization |
| 3974 |
Latrunculin B |
Inhibitor of actin polymerization |
| 3715 |
Narciclasine |
Antiproliferative agent; induces actin polymerization |
| 4535 |
Phalloidin |
Promotes actin polymerization |
| 5782 |
Phalloidin-FITC |
Green fluorescent cytoskeleton stain |
| 7201 |
Phalloidin-Janelia Fluor® 646 |
Red fluorescent F-actin probe |
| 5783 |
Phalloidin-TRITC |
Red-orange fluorescent cytoskeleton stain |
| 4401 |
SMIFH2 |
FH2 domain inhibitor; prevents actin nucleation |
| 4434 |
Wiskostatin |
N-WASP inhibitor; inhibits Arp2/3 activation |
|
|
|
| Kinesin
Inhibitors & Modulators |
|
| Cat. No. |
Product |
Activity |
| 4676 |
ARRY 520 trifluoroacetate |
Potent and selective kinesin spindle protein (KSP) inhibitor;
induces Mcl-1 degradation |
| 5399 |
BTB1 |
Selective and ATP-competitive Kif18A inhibitor |
| 5261 |
Dimethylenastron |
Inhibitor of mitotic motor kinesin Eg5 |
| 6837 |
GSK 923295A |
Potent and selective centromere associated protein E (CENP-E)
allosteric inhibitor |
| 5408 |
Ispinesib |
High affinity and selective allosteric KSP inhibitor |
| 6664 |
Kinesore |
Kinesin-1 modulator; cell permeable |
| 1305 |
Monastrol |
Selective inhibitor of mitotic kinesin Eg5 |
| 2191 |
S-Trityl-L-cysteine |
Potent, selective inhibitor of mitotic kinesin Eg5 |
|
|
|
| Microtubules
Inhibitors |
|
| Cat. No. |
Product |
Activity |
| 6043 |
AMBMP hydrochloride |
Tubulin polymerization inhibitor; also Wnt canonical signaling
activator |
| 2186 |
CMPD-1 |
Tubulin polymerization inhibitor; also selective inhibitor of
p38α-mediated MK2a phosphorylation |
| 1364 |
Colchicine |
Inhibitor of tubulin |
| 6273 |
CRT 0105950 |
Disrupts microtubule organization; potent LIMK1/2 inhibitor |
| 6779 |
Davunetide |
Highly potent active component of ADNP; increases
tau-microtubule interactions |
| 4056 |
Docetaxel |
Microtubule stabilizer |
| 2226 |
Flutax 1 |
Fluorescent taxol derivative; microtubule stain |
| 6254 |
Flutax 2 |
Green fluorescent taxol derivative; binds microtubules |
| 5075 |
Harmine |
Potent and selective Dyrk1A inhibitor; inhibits tau
phosphorylation |
| 3728 |
Indibulin |
Microtubule destabilizer |
| 4997 |
INDY |
Dyrk1A/B inhibitor; inhibits abberant tau phosphorylation |
| 5231 |
MPC 6827 hydrochloride |
Inhibitor of microtubule polymerization; antimitotic and
antitumor |
| 1228 |
Nocodazole |
Microtubule inhibitor |
| 1097 |
Taxol |
Promotes assembly and inhibits disassembly of microtubules |
| 1256 |
Vinblastine sulfate |
Disrupts microtubules |
| 1257 |
Vincristine sulfate |
Disrupts microtubules |
|
|
|
| Myosin
Inhibitors |
|
| Cat. No. |
Product |
Activity |
| 1760 |
(±)-Blebbistatin |
Selective inhibitor of myosin II ATPase activity |
| 1852 |
(S)-(-)-Blebbistatin |
Selective inhibitor of myosin II ATPase activity. Active
enantiomer of (±)-blebbistatin |
| 1853 |
(R)-(+)-Blebbistatin |
Selective inhibitor of myosin II ATPase activity. Inactive
enantiomer of (±)-blebbistatin |
| 1870 |
BTS |
Selective inhibitor of skeletal muscle myosin II ATPase activity |
|
|
|
| Mitosis
Inhibitors |
|
| Cat. No. |
Product |
Activity |
| 7907 |
DC 432 |
Potent peptidomimetic inhibitor of N-terminal methyltransferase
1/2 |
| 7734 |
proTAME |
Cell-permeable APC/C inhibitor |