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제품 상세
의약품 안전성과 유효성 평가서비스 | Safety and Efficacy Service 이미지

의약품 안전성과 유효성 평가서비스 | Safety and Efficacy Service

Eurofins Discovery의 Spectrum Screen, BioPrint, Safety Screen 87, Safety Screen Functional, Safety Screen 44 스크리닝 서비스를 통해 약물의 유효성, 부작용, 안전성을 측정해 드립니다.

프린트 제품 문의

특징

 

  • 개발된 의약품의 안전성과 유효성을 측정합니다.
  • off-target related adverse drug reactions (ADRs)을 조기에 식별하여 unsafe compounds를 탐지하거나 더 효과적인 약물을 디자인 하는데 유용합니다.
  • GPCR, Ion channel, Transporter, Kinase등 다양한 family 및 target에 대해 스크리닝을 진행합니다.
  • Drug Discovery 단계에 따른 Tier 1, 2, 3 별로 포괄적인 panel을 제공합니다.
    • Tier 1  Safety Panel : Safety Screen 44 Panels & SAFETYscan47 Functional Panel
    • Tier 2  Safety Panel : Safety Screen 87 Panels
    • Tier 3  Safety Panel : Spectrum Screen Panels & BioPrint Profile Panel




종류 

 

FAMILY Service Spectrum Screen BioPrint Safety Screen 87 Safety Screen Functional  Safety Screen 44
Cat. No. PP16 P22-p  PP223 P347 PP241
No. of Targets 174 132 87 64 44
Cell Surface  GHB  Ⅴ 　 　 　 　
Cell Surface IL-6 Human Ⅴ 　 　 　 　
Cell Surface  Interleukin IL-1 R1 Ⅴ 　 　 　 　
Cell Surface  TNF-alpha 　 Ⅴ 　 　 　
Cytosolic QR2 / MT3 　 Ⅴ 　 　 　
Cytoskeleton Tubulin  Ⅴ 　 　 　 　
GPCR 5-HT1A Ⅴ Ⅴ Ⅴ Ⅴ* Ⅴ
GPCR 5-HT1B  Ⅴ Ⅴ Ⅴ Ⅴ* Ⅴ
GPCR 5-HT1D 　 Ⅴ 　 　 　
GPCR 5-HT2A 　 Ⅴ Ⅴ Ⅴ* Ⅴ
GPCR 5-HT2B  Ⅴ Ⅴ Ⅴ Ⅴ* Ⅴ
GPCR 5-HT2C  Ⅴ Ⅴ Ⅴ 　 　
GPCR 5-HT3A 　 　 Ⅴ 　 　
GPCR 5-HT4  Ⅴ Ⅴ 　 　 　
GPCR 5-HT5A  Ⅴ 　 　 　 　
GPCR 5-HT6  Ⅴ Ⅴ 　 　 　
GPCR 5-HT7  Ⅴ Ⅴ 　 　 　
GPCR A1  Ⅴ Ⅴ Ⅴ 　 　
GPCR A2A  Ⅴ Ⅴ Ⅴ Ⅴ* Ⅴ
GPCR A2B  Ⅴ Ⅴ 　 　 　
GPCR A3  Ⅴ Ⅴ 　 　 　
GPCR alpha1A  Ⅴ Ⅴ Ⅴ Ⅴ* Ⅴ
GPCR alpha1B  Ⅴ Ⅴ Ⅴ 　 　
GPCR alpha1D  Ⅴ 　 Ⅴ 　 　
GPCR alpha2A Ⅴ Ⅴ Ⅴ Ⅴ* Ⅴ
GPCR alpha2B  Ⅴ Ⅴ Ⅴ 　 　
GPCR alpha2C  Ⅴ Ⅴ 　 　 　
GPCR APJ  Ⅴ Ⅴ 　 　 　
GPCR AT1  Ⅴ Ⅴ Ⅴ 　 　
GPCR AT2  Ⅴ Ⅴ 　 　 　
GPCR B1  Ⅴ 　 　 　 　
GPCR B2  Ⅴ Ⅴ Ⅴ 　 　
GPCR BB1  Ⅴ 　 　 　 　
GPCR BB2 Ⅴ 　 　 　 　
GPCR BB3  Ⅴ Ⅴ 　 　 　
GPCR beta1 Ⅴ Ⅴ Ⅴ Ⅴ* Ⅴ
GPCR beta2  Ⅴ Ⅴ Ⅴ Ⅴ* Ⅴ
GPCR beta3  Ⅴ Ⅴ 　 　 　
GPCR BLT1 (LTB4) Ⅴ 　 　 　 　
GPCR CB1  Ⅴ Ⅴ Ⅴ Ⅴ* Ⅴ
GPCR CB2  Ⅴ Ⅴ Ⅴ Ⅴ* Ⅴ
GPCR CCK1 (CCKA)  Ⅴ Ⅴ Ⅴ Ⅴ* Ⅴ
GPCR CCK2 (CCKB)  Ⅴ Ⅴ Ⅴ 　 　
GPCR CCR1  Ⅴ 　 Ⅴ 　 　
GPCR CCR2  Ⅴ Ⅴ 　 　 　
GPCR CCR5  Ⅴ 　 　 　 　
GPCR CGRP (CLR/RAMP1) Ⅴ 　 　 　 　
GPCR CRF1  Ⅴ Ⅴ 　 　 　
GPCR CT  Ⅴ 　 　 　 　
GPCR CX3CR1  Ⅴ 　 　 　 　
GPCR CXCR1 (IL-8RA)  Ⅴ 　 　 　 　
GPCR CXCR2 (IL-8RB)  Ⅴ 　 Ⅴ 　 　
GPCR CXCR3  Ⅴ 　 　 　 　
GPCR CXCR4  Ⅴ 　 　 　 　
GPCR CysLT1  Ⅴ Ⅴ Ⅴ 　 　
GPCR CysLT2  Ⅴ 　 　 　 　
GPCR D1  Ⅴ Ⅴ Ⅴ Ⅴ* Ⅴ
GPCR D2L 　 　 Ⅴ Ⅴ* 　
GPCR D2S  Ⅴ Ⅴ Ⅴ 　 Ⅴ
GPCR D3  Ⅴ Ⅴ 　 　 　
GPCR D4 Ⅴ 　 　 　 　
GPCR D5  Ⅴ 　 　 　 　
GPCR delta (DOP)  Ⅴ Ⅴ Ⅴ Ⅴ* Ⅴ
GPCR DP1 Ⅴ 　 　 　 　
GPCR DP2 Ⅴ 　 　 　 　
GPCR EP1 Ⅴ 　 　 　 　
GPCR EP2 Ⅴ Ⅴ 　 　 　
GPCR EP3 Ⅴ 　 　 　 　
GPCR EP4 Ⅴ 　 　 　 　
GPCR ETA Ⅴ Ⅴ Ⅴ Ⅴ* Ⅴ
GPCR ETB Ⅴ Ⅴ 　 　 　
GPCR FP Ⅴ Ⅴ 　 　 　
GPCR GABAB (B1a/B2) Ⅴ 　 Ⅴ 　 　
GPCR GABAB (B1b/B2) Ⅴ 　 　 　 　
GPCR GHSR Ⅴ 　 　 　 　
GPCR Glucagon Ⅴ Ⅴ 　 　 　
GPCR GnRH Ⅴ 　 　 　 　
GPCR H1 Ⅴ Ⅴ Ⅴ Ⅴ* Ⅴ
GPCR H2 Ⅴ Ⅴ Ⅴ Ⅴ* Ⅴ
GPCR H3 Ⅴ Ⅴ 　 　 　
GPCR H4R Ⅴ Ⅴ 　 　 　
GPCR IP Ⅴ Ⅴ 　 　 　
GPCR kappa (KOP) Ⅴ Ⅴ Ⅴ Ⅴ* Ⅴ
GPCR M1 Ⅴ Ⅴ Ⅴ Ⅴ* Ⅴ
GPCR M2 Ⅴ Ⅴ Ⅴ Ⅴ* Ⅴ
GPCR M3 Ⅴ Ⅴ Ⅴ Ⅴ* Ⅴ
GPCR M4 Ⅴ Ⅴ Ⅴ 　 　
GPCR M5 Ⅴ 　 　 　 　
GPCR MC1 Ⅴ Ⅴ Ⅴ 　 　
GPCR MC3 Ⅴ Ⅴ 　 　 　
GPCR MC4 Ⅴ Ⅴ Ⅴ 　 　
GPCR MC5 Ⅴ 　 　 　 　
GPCR MCH1 Ⅴ Ⅴ 　 　 　
GPCR mGlu2 Ⅴ 　 　 　 　
GPCR mGlu5 Ⅴ 　 Ⅴ 　 　
GPCR Motilin Ⅴ Ⅴ 　 　 　
GPCR MT1 Ⅴ Ⅴ 　 　 　
GPCR MT2 Ⅴ 　 　 　 　
GPCR mu (MOP) Ⅴ Ⅴ Ⅴ Ⅴ* Ⅴ
GPCR NK1 Ⅴ Ⅴ Ⅴ 　 　
GPCR NK2 Ⅴ Ⅴ 　 　 　
GPCR NK3 Ⅴ 　 　 　 　
GPCR Acetylcholine (Muscarinic), Non-Selective Ⅴ 　 　 　 　
GPCR P2Y, Non-Selective Ⅴ 　 　 　 　
GPCR NOP (ORL1) Ⅴ Ⅴ 　 　 　
GPCR NT1 Ⅴ 　 　 　 　
GPCR OT Ⅴ 　 　 　 　
GPCR OX1 Ⅴ 　 　 　 　
GPCR OX2 Ⅴ 　 　 　 　
GPCR PAF Ⅴ Ⅴ Ⅴ 　 　
GPCR sst1 Ⅴ Ⅴ 　 　 　
GPCR sst2 Ⅴ 　 　 　 　
GPCR sst3 Ⅴ 　 　 　 　
GPCR sst4 Ⅴ Ⅴ 　 　 　
GPCR sst5 Ⅴ 　 　 　 　
GPCR TRH Ⅴ 　 　 　 　
GPCR UT (GPR14) Ⅴ Ⅴ 　 　 　
GPCR V1A Ⅴ Ⅴ Ⅴ Ⅴ* Ⅴ
GPCR V1B Ⅴ 　 　 　 　
GPCR V2 Ⅴ Ⅴ 　 　 　
GPCR VIP1 (VPAC1) Ⅴ Ⅴ 　 　 　
GPCR VIP2 (VPAC2) Ⅴ 　 　 　 　
GPCR Y1 Ⅴ Ⅴ Ⅴ 　 　
GPCR Y2 Ⅴ 　 　 　 　
Ion Channel 5-HT3A Ⅴ Ⅴ 　 　 Ⅴ
Ion Channel Cav1.2 (L-type) (Dihydropyridine Site) Ⅴ Ⅴ Ⅴ 　 Ⅴ
Ion Channel Cav1.2 (L-type) (Diltiazem Site) Ⅴ Ⅴ Ⅴ 　 　
Ion Channel Cav1.2 (L-type) (Verapamil Site) Ⅴ Ⅴ Ⅴ 　 　
Ion Channel Cav1.2 (L-type) 　 　 　 Ⅴ 　
Ion Channel Cav2.2 (N-type) Ⅴ Ⅴ Ⅴ 　 　
Ion Channel Glutamate (AMPA, Non-Selective) Ⅴ Ⅴ Ⅴ 　 　
Ion Channel Glutamate (Kainate, Non-Selective)  Ⅴ Ⅴ Ⅴ 　 　
Ion Channel Glutamate (NMDA, Non-Selective)  Ⅴ Ⅴ Ⅴ 　 Ⅴ
Ion Channel Glutamate (NMDA, Non-Selective)  Ⅴ Ⅴ Ⅴ 　 　
Ion Channel Glutamate (Non-Selective)  Ⅴ Ⅴ Ⅴ 　 　
Ion Channel Glutamate, NMDA Ⅴ 　 Ⅴ 　 　
Ion Channel hERG Ⅴ 　 Ⅴ Ⅴ Ⅴ
Ion Channel IP3R1 Ⅴ 　 　 　 　
Ion Channel KATP Ⅴ 　 Ⅴ 　 　
Ion Channel KCNQ1 　 　 　 Ⅴ 　
Ion Channel KV (Non-Selective)  Ⅴ 　 　 　 Ⅴ
Ion Channel nAChR (alpha1)  Ⅴ 　 Ⅴ 　 　
Ion Channel nAChR (alpha3/beta4)  Ⅴ 　 Ⅴ 　 　
Ion Channel nAChR (alpha4/beta2)  Ⅴ Ⅴ 　 Ⅴ Ⅴ
Ion Channel nAChR (alpha7) Human Ⅴ 　 　 　 　
Ion Channel nAChR (alpha7) Rat Ⅴ 　 　 　 　
Ion Channel nAChR (Muscle-Type)  　 Ⅴ 　 　 　
Ion Channel Nav1.5 　 　 　 Ⅴ 　
Ion Channel GABAA (alpha1/beta2/gamma2)  　 Ⅴ 　 Ⅴ 　
Ion Channel GABAA [3H]  Non-Selective Ⅴ Ⅴ 　 　 　
Ion Channel GABAA [3H]  Ⅴ 　 　 　 　
Ion Channel GABAA [3H]  Ⅴ Ⅴ Ⅴ 　 　
Ion Channel GABAA [3H]   　 　 Ⅴ 　 Ⅴ
Ion Channel GABAA [3H]  　 　 Ⅴ 　 　
Ion Channel Glycine [3H]  Ⅴ 　 Ⅴ 　 　
Ion Channel P2X, Non-Selective Ⅴ 　 　 　 　
Ion Channel Sodium Ion Channel [3H],Non-Selective, Ⅴ Ⅴ Ⅴ 　 Ⅴ
Ion Channel Gabapentin Ⅴ 　 　 　 　
Ion Channel RY3 Ⅴ 　 　 　 　
Ion Channel SKCa (Non-Selective) Ⅴ Ⅴ 　 　 　
Kinase Abl 　 Ⅴ 　 　 　
Kinase CaMK2alpha 　 Ⅴ 　 　 　
Kinase CDK2 / cyclinA 　 Ⅴ 　 　 　
Kinase EGFR Ⅴ 　 　 　 　
Kinase ERK2 (MAPK1) 　 Ⅴ 　 　 　
Kinase Flt-1 (VEGFR1) 　 Ⅴ 　 　 　
Kinase Fyn 　 Ⅴ 　 　 　
Kinase IR Ⅴ Ⅴ Ⅴ 　 　
Kinase lck 　 　 Ⅴ Ⅴ Ⅴ
Kinase LYN 　 Ⅴ 　 　 　
Kinase PKCalpha 　 　 Ⅴ 　 　
Kinase PDGFR (Non-Selective)  Ⅴ 　 　 　 　
Kinase SAPK2A (p38alpha) 　 Ⅴ 　 　 　
Kinase TGFbeta (Non-Selective)  Ⅴ 　 　 　 　
Kinase ZAP70 　 Ⅴ 　 　 　
Lipid Metabolism COX1 　 Ⅴ Ⅴ Ⅴ Ⅴ
Lipid Metabolism COX2 　 Ⅴ Ⅴ Ⅴ Ⅴ
Nitrogen Metabolism iNOS 　 Ⅴ 　 　 　
NHR AR Ⅴ Ⅴ Ⅴ 　 Ⅴ
NHR ERalpha Ⅴ Ⅴ Ⅴ 　 　
NHR ERbeta Ⅴ 　 　 　 　
NHR GR Ⅴ Ⅴ Ⅴ 　 Ⅴ
NHR LXRbeta 　 Ⅴ 　 　 　
NHR MCR Ⅴ 　 　 　 　
NHR PPARgamma 　 Ⅴ Ⅴ 　 　
NHR PR Ⅴ 　 Ⅴ 　 　
NHR RARalpha 　 Ⅴ 　 　 　
NHR RXRalpha Ⅴ 　 　 　 　
NHR TR (Non-Selective)  Ⅴ 　 　 　 　
NHR VDR Ⅴ 　 　 　 　
Nucleotide Signaling Atrial Natriuretic Factor (ANF, Non-Selective)  Ⅴ 　 　 　 　
Nucleotide Signaling Guanylyl Cyclase 　 Ⅴ 　 　 　
Neurotransmitter Metabolism Acetylcholinesterase 　 Ⅴ Ⅴ Ⅴ Ⅴ
Neurotransmitter Metabolism Monoamine Oxidase A (MAO-A) 　 Ⅴ Ⅴ Ⅴ Ⅴ
Neurotransmitter Metabolism Monoamine Oxidase B (MAO-B) 　 　 Ⅴ 　 　
Other Phorbol Ester  Ⅴ 　 　 　 　
PDE PDE2A 　 Ⅴ 　 　 　
PDE PDE3A 　 　 　 Ⅴ Ⅴ
PDE PDE3B 　 Ⅴ Ⅴ 　 　
PDE PDE4D 　 Ⅴ Ⅴ Ⅴ Ⅴ
PDE PDE5 　 Ⅴ 　 　 　
PDE PDE6 　 Ⅴ 　 　 　
PDE Rolipram  Ⅴ 　 　 　 　
Protease ACE 　 Ⅴ Ⅴ 　 　
Protease ACE2 　 Ⅴ 　 　 　
Protease beta-Secretase 1 　 Ⅴ 　 　 　
Protease Caspase 3 　 Ⅴ 　 　 　
Protease Cathepsin G 　 　 Ⅴ 　 　
Protease HIV-1 　 Ⅴ 　 　 　
Protease MMP1 　 Ⅴ 　 　 　
Protease MMP2 　 Ⅴ 　 　 　
Protease MMP9 　 Ⅴ 　 　 　
Steroid Metabolism Xanthine Oxidase 　 Ⅴ 　 　 　
Transmembrane Imidazoline I2 Ⅴ 　 　 　 　
Transmembrane sigma1  Ⅴ Ⅴ 　 　 　
Transmembrane  sigma2  Ⅴ 　 　 　 　
Transporter Adenosine  Ⅴ 　 Ⅴ 　 　
Transporter ATPase 　 Ⅴ Ⅴ 　 　
Transporter CHT1  Ⅴ Ⅴ 　 　 　
Transporter DAT Ⅴ Ⅴ Ⅴ Ⅴ Ⅴ
Transporter GABA (Non-Selective)  Ⅴ Ⅴ Ⅴ 　 　
Transporter GLYT1  Ⅴ 　 　 　 　
Transporter NET  Ⅴ Ⅴ Ⅴ Ⅴ Ⅴ
Transporter SET Ⅴ Ⅴ Ⅴ Ⅴ Ⅴ
Transporter VMAT (Non-Selective)  Ⅴ 　 　 　 　

  *cell-based 타겟중 agonist &antagonist 

 

주문정보

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
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Safety and Efficacy 분석서비스 . . EUROFINS DISCOVERY
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관련제품

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet

자료

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    분석실험/제작서비스 Vol.2 이미지

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    동영상 보기
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    신약개발 서비스에 대한 안내입니다.

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제품 문의

 0.5 ml Elite Pre-stained Protein Ladder (2 x 0.25 ml) PAL-EPL-500 0.5ml 500
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