고마바이오텍(주)

로그인이 필요합니다.

Category 전체보기
전기영동 > 단백질 전기영동 전기영동 > 헥산 전기영동
Cat. No.전체보기

검색 결과가 없습니다.

Product전체보기

검색 결과가 없습니다.

Brand전체보기

검색 결과가 없습니다.

제품 상세

Antibody

6.5 - 270 kDa 범위를 커버하는 3가지 컬러 밴드를 포함하며,
최대 100%까지의 transfer 효과를 개런티하는 Prestained protein ladder를 소개합니다.

프린트 제품 문의

특징 

 

  • Nuclear receptors는 nuclear hormone receptor로도 알려져 있는 DNA에 직접적으로 결합하여 목표 유전자의 발현을 조절하는 전사인자 중 한 family입니다. 성 스테로이드, 비타민D3, 아드레날 스테로이드, 그 외 대사 리간드 등을 조절하며, 대사, 발생, 생식에 관련되어 있습니다. 
  • Nuclear Receptor superfamily는 크게 6가지로 나뉩니다. 

1) Thyroid Hormone Receptor-like : thyroid receptor, retinoic acid receptor, PPAR, LXR, FXR, VDR, PXR and CAR 등

2) Retinoid X Receptor-like : RXR 등

3) Estrogen Receptor-like (steroid hormone receptors이라고도 불림) : receptors for estrogen (ER), androgen, glucocorticoid, mineralocorticoid and progesterone

4) Nerve Growth Factor IB-like

5) Steroidogenic Factor-like

6) Germ Cell Nuclear Factor-like

 



주요 제품

 

Androgen Receptor
　 Cat. No. Product Activity
Androgen Receptor Agonists 5274 BMS 564929 Highly potent and muscle-selective androgen receptor (AR) agonist
3812 Cl-4AS-1 Steroidal androgen receptor agonist
2822 Testosterone Endogenous androgen receptor agonist
Androgen Receptor Antagonists 3389 Bicalutamide Non-steroidal androgen receptor antagonist
6158 (S)-Equol Dihydrotestosterone antagonist; potent estrogen receptor β (ERβ) agonist
4094 Flutamide Non-steroidal androgen receptor antagonist
6108 Galeterone Androgen receptor antagonist; also CYP17 inhibitor
Androgen Receptor Modulators 3813 TFM-4AS-1 Selective androgen receptor modulator (SARM)
Androgen Receptor Inhibitors 5842 MK 386 Potent, selective human type 1 5α-reductase inhibitor
Degraders 7254 ARCC 4 Potent and selective androgen receptor degrader
Other 4946 AIM 100 Potent and selective Ack1 inhibitor
3293 Finasteride Type II 5α-reductase inhibitor
3572 GSK 650394 Serum- and glucocorticoid-regulated kinase (SGK) inhibitor
4396 Piperlongumine Induces apoptosis; depletes androgen receptors in prostate cancer cells
2968 Spironolactone Antiandrogen; inhibits steroid hormone biosynthesis. Also MR antagonist
6223 XY 018 Inhibits AR expression; RORγ antagonist
PPAR 
퍼옥시좀 증식자 활성화 수용체(PPAR) 는 유전자 발현을 조절하기 위해 레티노이드 X 수용체(RXR) 동형과 이종 이량체화하는 리간드 활성화 전사 인자의 핵 수용체 패밀리의 구성원입니다. PPAR의 세가지 하위유형(α, δ(β라고도 함) 및 γ)이 확인 및 복제되었습니다. 많은 내인성 리간드가 PPAR에 대해 분리되었는데, 프로스타사이클린, 지방산, 리소포스파티딘산 및 류코트리엔 B4가 포함됩니다. PPAR은 지질 항상성, 세포 증식, 분화, 지방 생성 및 면역 기능을 포함하여 세포에서 많은 중요한 역할을 하며 대사 질환의 치료에 유용합니다.
PPARα
　 Cat. No. Product Name Activity
PPARα Agonists 4190 CP 775146 Selective, high affinity PPARα agonist
4113 Fenofibrate PPARα agonist
1677 GW 7647 Highly selective, potent PPARα agonist. Orally active
1484 Oleylethanolamide PPARα agonist; also GPR55 agonist
0879 Palmitoylethanolamide Endogenous lipid with PPARα agonist activity
1312 WY 14643 Selective PPARα agonist
PPARα Antagonists 4618 GW 6471 PPARα antagonist
1311 MK 886 PPARα antagonist. Also FLAP inhibitor
PPARγ
　 Cat. No. Product Name Activity
PPARγ Agonists 1307 Ciglitazone Selective PPARγ agonist
4784 Edaglitazone Potent and selective PPARγ agonist; antidiabetic
1664 GW 1929 hydrochloride Selective PPARγ agonist. Orally active
2150 nTZDpa Potent, selective PPARγ partial agonist
4124 Pioglitazone hydrochloride Selective PPARγ agonist; antidiabetic agent
2306 15-deoxy-Δ-12,14-Prostaglandin J2 Endogenous PPARγ agonist
5325 Rosiglitazone Potent and selective PPARγ agonist; antidiabetic agent
5139 Telmisartan PPARγ partial agonist; AT1 antagonist
3114 Troglitazone Selective PPARγ agonist; antidiabetic agent
PPARγ Antagonists 4344 FH 535 PPARγ/δ antagonist; also inhibits Wnt/β-catenin signaling
1508 GW 9662 Selective covalent PPARγ antagonist
6383 SR 16832 Dual site PPARγ inhibitor
2022 SR 202 Selective PPARγ antagonist; antidiabetic and antiobesity agent
2301 T 0070907 Highly potent and selective covalent PPARγ antagonist
Other 1110 Genistein PPARγ ligand. Also estrogen receptor ligand and EGFR inhibitor
5920 LG 100268 Activates RXR/PPARγ heterodimers; potent and selective RXR agonist
4409 SR 1664 High affinity PPARγ ligand; blocks Cdk5-dependent PPARγ phosphorylation
PPARδ
　 Cat. No. Product Name Activity
PPARδ Agonists 2229 GW 0742 Highly selective, potent PPARδ agonist
5674 GW 501516 Potent and selective PPARδ agonist
1856 L-165,041 Potent PPARδ agonist
PPARδ Antagonists 4344 FH 535 PPARγ/δ antagonist; also inhibits Wnt/β-catenin signaling
3433 GSK 0660 Selective PPARδ antagonist
3961 GSK 3787 Potent and selective PPARδ antagonist
Aryl Hydrocarbon Receptor
　 Cat. No. Product Activity
Aryl Hydrocarbon Receptor Agonists 6321 10-Cl-BBQ Potent aryl hydrocarbon receptor (AhR) agonist; orally bioavailable
5304 FICZ High affinity aryl hydrocarbon receptor (AhR) agonist
1803 ITE Endogenous agonist for the transcription factor aryl hydrocarbon receptor
3873 MeBIO AhR agonist. Inactive analog of BIO (Cat. No. 3194)
1267 Pifithrin-α hydrobromide Aryl hydrocarbon receptor agonist. Also p53 inhibitor
Aryl Hydrocarbon Receptor Antagonists 3858 CH 223191 Potent aryl hydrocarbon receptor (AhR) antagonist
7086 StemRegenin 1 Aryl hydrocarbon receptor (AhR) antagonist; promotes HSC expansion and engraftment
Ligands 4393 L-Kynurenine Tryptophan catabolite; endogenous aryl hydrocarbon receptor ligand
Other 4995 Phortress Prodrug of the antitumor agent 5F 203
Pregnane X Receptor
　 Cat. No. Product Name Activity
Pregnane X Receptor Agonists 4245 Meclizine dihydrochloride Human pregnane X receptor agonist; H1 antagonist
4121 Rifampicin Pregnane X receptor agonist; antibiotic
5359 Rifaximin Pregnane X receptor agonist; antibiotic
2969 SR 12813 Pregnane X receptor agonist
Constitutive Androstane Receptor
　 Cat. No. Product Name Activity
Constitutive Androstane Receptor Agonists 3683 CITCO Selective CAR agonist
1225 TCPOBOP Constitutive androstane receptor agonist
Constitutive Androstane Receptor Inverse Agonists 4096 Clotrimazole CAR inverse agonist; Also Cytochrome P450 inhibitor
5188 S 07662 Constitutive androstane receptor (CAR) inverse agonist
2373 T 0901317 CAR inverse agonist; Also potent LXR agonist
Constitutive Androstane Receptor Antagonists 5605 CINPA 1 Potent CAR antagonist
670 PK 11195 CAR antagonist. Also peripheral benzodiazepine receptor antagonist
Progesterone Receptors
　 Cat. No. Product Name Activity
Progesterone Receptor Agonists 4833 Levonorgestrel Synthetic progesterone analog
6285 Megestrol Acetate Synthetic progesterone analog
4115 Mometasone furoate Synthetic corticosteroid; anti-inflammatory agent
2835 Progesterone Endogenous progesterone receptor agonist
Progesterone Receptor Antagonists 1479 Mifepristone Progesterone and glucocorticoid receptor antagonist
Other 6242 AG 205 Progesterone receptor membrane component 1 (Pgrmc1) ligand
Estrogen and Related Receptors
　 Cat. No. Product Name Activity
Estrogen and Related Receptor Agonists 5053 AC 186 Potent and selective ERβ agonist; neuroprotective
1417 Daidzein Estrogen receptor agonist. Also induces cell cycle arrest
1494 DPN Highly potent ERβ agonist
4494 (R)-DPN Enantiomer of DPN (Cat. No. 1494)
2266 DY131 Agonist selective for estrogen-related receptors ERRβ and ERRγ
6158 (S)-Equol Potent estrogen receptor β (ERβ) agonist; dihydrotestosterone antagonist
4276 ERB 041 Potent ERβ agonist
2823 α-Estradiol Endogenous estrogen receptor agonist
2824 β-Estradiol Endogenous ER agonist
3523 FERb 033 Potent and selective ERβ agonist
3075 GSK 4716 Selective ERRγ and ERRβ agonist
3907 27-Hydroxycholesterol ER partial agonist; also LXR agonist
1426 PPT Subtype-selective ERα agonist
3366 WAY 200070 Selective ERβ agonist
Estrogen and Related Receptor Inverse Agonists 3928 XCT 790 Selective ERRα inverse agonist
Estrogen and Related Receptor Antagonists 1047 ICI 182,780 Estrogen receptor antagonist
1991 MPP dihydrochloride Highly selective ERα antagonist
2662 PHTPP Selective ERβ antagonist
2183 ZK 164015 Potent estrogen receptor antagonist
Estrogen and Related Receptor Modulators 5263 Bazedoxifene acetate Potent and selective estrogen receptor modulator (SERM)
3412 (Z)-4-Hydroxytamoxifen Metabolite of tamoxifen (Cat. No. 0999)
2280 Raloxifene hydrochloride Selective estrogen receptor modulator (SERM)
6342 Tamoxifen Estrogen receptor partial agonist/antagonist
0999 Tamoxifen citrate Estrogen receptor partial agonist/antagonist
2676 Y 134 Selective estrogen receptor modulator (SERM), selective for ERα
Estrogen and Related Receptor Inhibitors 4382 Letrozole Potent, reversible non-steroidal aromatase inhibitor
Degraders 7120 SNIPER(ER)-87 Potent and selective ERα Degrader (SNIPER)
Other 3388 Anastrozole Potent aromatase (CYP19) inhibitor
3705 Endoxifen Potent antiestrogen; ERα ligand
1110 Genistein Estrogen receptor ligand. Also tyrosine kinase inhibitor
1990 (R,R)-THC Potent subtype-selective ligand; ERα agonist/ERβ antagonist
3975 Zearalenone Estrogen receptor ligand; mycotoxin
Retinoic Acid Receptors
　 Cat. No. Product Name Activity
Retinoic Acid Receptor Agonists 4046 AC 261066 RARβ2 agonist
2436 AC 55649 Selective RARβ2 agonist
2852 Adapalene RARβ and RARγ agonist
0760 AM 580 Retinoic acid analog; RARα agonist
3507 AM 80 RARα agonist; anticancer agent
3505 BMS 753 RARα-selective agonist
3410 BMS 961 Selective RARγ agonist
2554 CD 1530 Potent and selective RARγ agonist
3824 CD 2314 Selective RARβ agonist
1549 CD 437 RARγ-selective agonist
2020 Ch 55 Potent RAR agonist
6873 DC 271 Fluorescent retinoic acid analog; solvochromatic probe
0695 Retinoic acid Endogenous retinoic acid receptor agonist
0761 TTNPB Retinoic acid analog; RAR agonist
Retinoic Acid Receptor Inverse Agonists 3509 BMS 493 Pan-RAR inverse agonist
Retinoic Acid Receptor Antagonists 5758 AGN 193109 High affinity pan-RAR antagonist
3660 BMS 195614 Selective RARα antagonist
3800 CD 2665 Selective RARβ/γ antagonist
3823 ER 50891 Selective RARα antagonist
2021 LE 135 Selective RARβ antagonist
5984 LY 2955303 High affinity and selective RARγ antagonist
3822 MM 11253 RARγ-selective antagonist
Other 3409 BMS 453 Synthetic retinoid and RARβ agonist; also RARα and RARγ antagonist
4011 EC 23 Synthetic retinoid; induces differentiation of stem cells
1396 Fenretinide Synthetic retinoid; antiproliferative and antioxidant
2705 Liarozole dihydrochloride Blocks retinoic acid metabolism
Glucocorticoid Receptor
　 Cat. No. Product Name Activity
Glucocorticoid Receptor Agonists 3685 Corticosterone Endogenous glucocorticoid
2007 Fluticasone propionate Selective high affinity glucocorticoid receptor agonist
4116 GSK 9027 Glucocorticoid receptor agonist
4819 Methylprednisolone Glucocorticoid receptor agonist
4115 Mometasone furoate Synthetic corticosteroid; anti-inflammatory agent
Glucocorticoid Receptor Antagonists 1479 Mifepristone Glucocorticoid and progesterone receptor antagonist
Glucocorticoid Receptor Inhibitors 6400 Alsterpaullone Glucocorticoid receptor inhibitor; also inhibits CDK1/2, GSK-3β and Lck
Other 2671 Budesonide Synthetic glucocorticoid; anti-inflammatory and chemopreventive
6357 Ciclesonide Glucocorticoid antiasthmatic prodrug
1126 Dexamethasone Anti-inflammatory glucocorticoid
4093 Hydrocortisone Adrenal glucocorticoid; immunosuppressant
Retinoic Acid-related Orphan Receptor
　 Cat. No. Product Name Activity
Retinoic Acid-related Orphan Receptor Agonists 6873 DC 271 Fluorescent retinoic acid analog; solvochromatic probe
5868 SR 0987 T cell-specific RORγ (RORγt) agonist
4874 SR 1078 RORα/γ agonist
Retinoic Acid-related Orphan Receptor Inverse Agonists 5987 (±)-ML 209 RORγt inverse agonist; suppresses Th17 cell differentiation
4869 SR 2211 Selective RORγ inverse agonist
Retinoic Acid-related Orphan Receptor Antagonists 6223 XY 018 RORγ antagonist; inhibits AR expression
Other 0695 Retinoic acid Endogenous retinoic acid receptor agonist; proposed RORβ ligand
LXR-like Receptor 
　 Cat. No. Product Name Activity
LXR-like Receptor Agonists 2563 Fexaramine Potent, selective farnesoid X receptor (FXR) agonist
2474 GW 3965 hydrochloride Orally active liver X receptor (LXR) agonist
2473 GW 4064 Selective farnesoid X receptor (FXR) agonist
3907 27-Hydroxycholesterol LXR agonist; also ER partial agonist
2373 T 0901317 Potent liver X receptor (LXR) agonist; also CAR inverse agonist
5951 WAY 252623 Potent LXR agonist
LXR-like Receptor Inverse Agonists 5854 SR 9238 Potent and selective LXR inverse agonist
6138 SR 9243 Selective LXR inverse agonist
LXR-like Receptor Antagonists 5656 DY 268 Potent FXR antagonist
6669 Gly MCA FXR antagonist; selectively active in intestines; orally bioavailable
5694 GSK 2033 Potent LXR antagonist
Retinoid X Receptor 
　 Cat. No. Product Name Activity
Retinoid X Receptor Agonists 5819 Bexarotene Potent and selective RXR agonist
3302 CD 3254 Potent and selective RXRα agonist
6873 DC 271 Fluorescent retinoic acid analog; solvochromatic probe
3687 Docosahexaenoic acid RXR agonist
5920 LG 100268 Potent and selective RXR agonist; also activates RXR/PPARγ heterodimers
0695 Retinoic acid Endogenous retinoic acid receptor agonist
3411 SR 11237 Pan RXR agonist
Retinoid X Receptor Antagonists 3912 HX 531 Potent RXR antagonist
5086 PA 452 RXR antagonist
3303 UVI 3003 RXR antagonist
Retinoid X Receptor Modulators 3508 LG 101506 Selective RXR modulator
Other 1396 Fenretinide Synthetic retinoid; antiproliferative and antioxidant
3913 HX 630 RXR synergist
2705 Liarozole dihydrochloride Blocks retinoic acid metabolism
Mineralocorticoid Receptor
　 Cat. No. Product Name Activity
Mineralocorticoid Receptor Agonists 3685 Corticosterone Endogenous glucocorticoid
Mineralocorticoid Receptor Antagonists 2397 Eplerenone Selective mineralocorticoid receptor antagonist
1672 RU 28318, potassium salt Potent, selective mineralocorticoid receptor antagonist
2968 Spironolactone Mineralocorticoid receptor antagonist
Rev-Erb Receptor
　 Cat. No. Product Name Activity
Rev-Erb Receptor Agonists 3663 GSK 4112 Selective Rev-Erbα agonist
6038 SR 10067 Selective Rev-Erbα/β agonist; anxiolytic
5855 SR 9009 Rev-Erbα/β agonist
Rev-Erb Receptor Antagonists 4463 SR 8278 Rev-Erbα antagonist
Nerve Growth Factor IB-like Receptor
　 Cat. No. Product Name Activity
Nerve Growth Factor IB-like Receptor Agonists 5459 Cytosporone B High affinity Nur77 agonist
6376 DIM-C-pPhOCH3 Nur77 agonist
6017 THPN Nur77 agonist; induces autophagy in melanoma cell lines
Nerve Growth Factor IB-like Receptor Antagonists 6377 DIM-C-pPhOH Nur77 antagonist
Nerve Growth Factor IB-like Receptor Activators 5821 C-DIM 12 Nurr1 activator; inhibits NF-κB-dependent gene expression
5699 IP7e Potent Nurr1 activator
Vitamin D Receptor 
　 Cat. No. Product Name Activity
Vitamin D Receptor Agonists 2551 Calcitriol Vitamin D receptor (VDR) agonist
3993 EB 1089 Vitamin D receptor (VDR) agonist
Other 4036 Calcifediol Prohormone of calcitriol (Cat. No. 2551). Major circulating form of vitamin D
2700 Calcipotriol Vitamin D3 analog
4146 Ercalcidiol Metabolite of vitamin D2
4160 22-Oxacalcitriol Non-calcemic vitamin D3 (Cat. No. 4156) analog
4161 Paricalcitol Analog of the active form of vitamin D2
Other Nuclear Receptor
　 Cat. No. Product Name Activity
Other Nuclear Receptor Agonists 4554 GC 1 High affinity thyroid receptor α (TRα) and TRβ agonist; thyromimetic
Other Nuclear Receptor Inverse Agonists 4957 ML 179 Selective liver receptor homolog 1 (LRH1) inverse agonist
Other Nuclear Receptor Antagonists 3440 SID 7969543 Selective steroidogenic factor-1 (SF-1, NR5A1) inhibitor
Degraders 7388 ND1-YL2 SRC-1 peptide-based Degrader; active in vivo
Other 2013 Guggulsterone Broad spectrum steroid receptor ligand. Antagonizes FXR and displays hypolipidemic activity
3570 Z-Guggulsterone Broad spectrum steroid receptor ligand. More active isomer of guggulsterone (Cat. No. 2013)
5964 SI-2 hydrochloride Steroid receptor coactivator 3 (SRC-3) inhibitor
6666 T3 Thyroid hormone; also promotes differentiation of oligodendroglial precursor cells

주문정보

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS
전체보기

추천제품

관련제품

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS
전체보기

자료

웨비나/Video

TOP

제품 문의

 0.5 ml Elite Pre-stained Protein Ladder (2 x 0.25 ml) PAL-EPL-500 0.5ml 500
Maker
Cat.No.
Product
Size
Qty
Data Sheet
MSDS

로그인

로그인