고마바이오텍(주)
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제품 상세

Antibody

6.5 - 270 kDa 범위를 커버하는 3가지 컬러 밴드를 포함하며,
최대 100%까지의 transfer 효과를 개런티하는 Prestained protein ladder를 소개합니다.

배경

  

  • MHC (Major Histocompatibility Complex, 주조직적합성항원)는 외부의 항원을 인식하여 항원성 펩타이드를 제시함으로써 T cell이 인지하여 면역을 유도합니다. class I은 대부분의 세포에서 발현되어 cytotoxic T cell의 면역을 유발하고, class II는 dendritic cell, mononuclear phagocyte등의 antigen presenting cell (APC)에서 발현되어 T helper cell에게 항원 조각을 제시함으로써 면역을 유도합니다. 
  • 이러한 MHC는 모든 척추동물들이 가지며 사람의 MHC를 HLA (Human Leukocyte Antigen), 마우스의 MHC를 H-2라고 합니다.
  • HLA는 이식시 유전적인 적합성 여부를 결정하는데 관여하며, Class I (HLA-A, B, C)과 Class II (HLA-DR, DQ, DP)분자로 나뉩니다. 

 


주요 제품  

 

anti-HLA A antibody (#ARG42193)
Product Description Rabbit Polyclonal antibody recognizes HLA A
Tested Reactivity Hu
Tested Application ICC/IF, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name HLA A
Antigen Species Human
Immunogen Synthetic peptide corresponding to aa. 82-106 of Human HLA A. (EYWDGETRKVKAHSQTHRVDLGTLR)
Conjugation Un-conjugated
Alternate Names MHC class I antigen A*1; HLAA; HLA class I histocompatibility antigen, A-1 alpha chain

 

 


 

 

anti-HLA B antibody (#ARG42146)
Product Description Rabbit Polyclonal antibody recognizes HLA B
Tested Reactivity Hu
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name HLA B
Antigen Species Human
Immunogen Synthetic peptide within aa. 1-100 of Human HLA-B. (NP_005505.2)
Conjugation Un-conjugated
Alternate Names SPDA1; HLAB; AS; MHC class I antigen B*7; HLA class I histocompatibility antigen, B-7 alpha chain

 


 

 

 

anti-HLA DR antibody [L243] (#ARG65720)
Product Description Mouse Monoclonal antibody [L243] recognizes HLA DR
Tested Reactivity Hu, Bb, Chimp, Dog, Mk, NHuPrm
Tested Application CyTOF®-candidate, FACS, FuncSt, ICC/IF, IHC-Fr, IHC-P, IP, WB
Specificity This antibody recognizes specifically HLA-DR molecules, both peptide-loaded and empty.
Host Mouse
Clonality Monoclonal
Clone L243
Isotype IgG2a
Target Name HLA DR
Antigen Species Human
Immunogen Human B lymphocytes
Conjugation Un-conjugated
Alternate Names MLRW; HLA class II histocompatibility antigen, DR alpha chain; HLA-DRA1; MHC class II antigen DRA

 

 

 

 

 

anti-HLA DP + DR antibody [HL-38] (#ARG63011)

Product Description Mouse Monoclonal antibody [HL-38] recognizes HLA DP + DR
Tested Reactivity Hu, Pig
Tested Application FACS, IHC-P, IP, WB
Specificity The clone HL-38 recognizes common epitope on beta-chain of human HLA-DR and HLA-DP. DR and DP are the isotypes of human MHC Class II molecules expressed on antigen-presenting cells (APC; dendritic cells, B lymphocytes, monocytes, macrophages).
Host Mouse
Clonality Monoclonal
Clone HL-38
Isotype IgG2a
Target Name HLA DP + DR
Antigen Species Human
Immunogen Raji Burkitt's lymphoma cell line
Conjugation Un-conjugated
Alternate Names MHC class II antigen DPB1; HLA-DP1B; HLA-DP; HLA class II histocompatibility antigen, DP; W4; DPB1; HLA class II histocompatibility antigen, DP beta 1 chain; HLA-DPB

 

 

 

anti-HLA DQA1 antibody (#ARG41711)
Product Description Rabbit Polyclonal antibody recognizes HLA DQA1
Tested Reactivity Hu, Ms, Rat
Tested Application IHC-P, IP, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name HLA DQA1
Antigen Species Human
Immunogen Synthetic peptide of Human HLA DQA1.
Conjugation Un-conjugated
Alternate Names HLA class II histocompatibility antigen, DQ alpha 1 chain; CELIAC1; HLA-DQA; MHC class II DQA1; CD; HLA-DCA; DC-alpha; GSE; DQ-A1; DC-1 alpha chain

 

 

 

 

주문정보

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS
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제품 문의

0.5 ml Elite Pre-stained Protein Ladder (2 x 0.25 ml) PAL-EPL-500 0.5ml 500
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