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제품 상세
RIP1 antibody 이미지

RIP1 antibody

RIP1 pSer166 antibody (ARG66476)가 NASH (비알콜성지방간염)의 병리학적인 연구에 이용되어, Cell Death Differ 논문에 발표되었습니다. 다양한 RIP activation marker를 확인하세요.

프린트 제품 문의

특징


  • NASH는 술 섭취와 상관없이 간에 지방이 축적되어 염증을 유발하는 질환으로, 섬유증, 간경화, 간암으로까지 이어질 수 있고, 비만 인구의 증가와 함께 NASH  환자도 급증하고 있습니다. 
  • 최근의 연구에서는 RIP1 활성화를 확인하는 마커인 RIP1 pSer166 항체를 이용하여 대식세포에서의 RIP1 활성이 Pyroptosis, apoptosis, necroptosis (PANoptosis)를 통해 NASH의 병리유전학에 관여하고 있음을 입증함으로써, Macrophage RIP1이 NASH의 잠재적 치료 타겟임을 보여주었습니다.

 

 

 

주요 제품

 

  • anti-RIPK1 / RIP1 phospho (Ser166) antibody (#ARG66476)   

Product Description Rabbit Monoclonal antibody [YJY-1-5] recognizes RIPK1 / RIP1 phospho (Ser166)
Tested Reactivity Ms, Rat
Tested Application ICC/IF, IHC-Fr, IHC-P, IP, WB
Host Rabbit
Clonality Monoclonal
Clone YJY-1-5
Isotype IgG
Target Name RIPK1 / RIP1
Antigen Species Mouse
Immunogen Phosphospecific peptide around Ser166 of Mouse RIPK1 / RIP1.
Conjugation Un-conjugated
Full Name receptor (TNFRSF)-interacting serine-threonine kinase 1
사용 논문 Neuronal MD2 Induces Long-term Mental Impairments in Septic Mice by Facilitating Necroptosis and Apoptosis
WB / Mouse
Zhongmin Fan et al.
Research Square,  (2021)

NEK1-mediated retromer trafficking promotes blood-brain barrier integrity by regulating glucose metabolism and RIPK1 activation.
WB / Mouse
Huibing Wang et al.
Nat Commun.,  (2021)

RIP1 kinase activity promotes steatohepatitis through mediating cell death and inflammation in macrophages.
WB, IHC-P / Mouse
Liang Tao et al.
Cell Death Differ.,  (2021)

  

 

  • anti-RIPK1 / RIP1 antibody (#ARG56458)  

 

Product DescriptionRabbit Polyclonal antibody recognizes RIPK1 / RIP1
Tested ReactivityHu
Tested ApplicationWB
HostRabbit
ClonalityPolyclonal
IsotypeIgG
Target NameRIPK1 / RIP1
Antigen SpeciesHuman
ImmunogenPartial recombinant protein corresponding to aa. 316-671 of Human RIPK1 / RIP1.
ConjugationUn-conjugated

 

 

 

  • anti-RIPK3 / RIP3 phospho (Ser232) antibody (#ARG41235) 

Product DescriptionRabbit Polyclonal antibody recognizes RIPK3 / RIP3 phospho (Ser232)
Tested ReactivityMs
Predict ReactivityRat
Tested ApplicationWB
HostRabbit
ClonalityPolyclonal
IsotypeIgG
Target NameRIPK3 / RIP3
Antigen SpeciesMouse
ImmunogenPhosphospecific peptide around Ser232 of Mouse RIPK3 / RIP3.
ConjugationUn-conjugated
Full Namereceptor-interacting serine-threonine kinase 3

 

 

 

  • anti-MLKL phospho (Ser358) antibody (#ARG40184) 

Product DescriptionRabbit Polyclonal antibody recognizes MLKL phospho (Ser358)
Tested ReactivityHu
Tested ApplicationIHC-P, WB
HostRabbit
ClonalityPolyclonal
IsotypeIgG
Target NameMLKL
Antigen SpeciesHuman
ImmunogenPhosphospecific peptide around Ser358 of Human MLKL.
ConjugationUn-conjugated
Full Namemixed lineage kinase domain-like

 

 

  



 

주문정보

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS
anti-NCOA1 / SRC1 antibody [SRC01 (GT12)] ARG62626 0.5 ml ARIGO
anti-NR1H4 / Farnesoid X Receptor antibody ARG64095 100 ug ARIGO
anti-RALBP1 antibody ARG59015 50 ug ARIGO
anti-RALBP1 antibody ARG58949 100 ul ARIGO
anti-RALBP1 antibody ARG59058 100 ul ARIGO
anti-RIP140 antibody ARG64977 100 ug ARIGO
anti-RIPK1 / RIP1 antibody ARG55746 50 ug ARIGO
anti-RIPK1 / RIP1 antibody ARG40301 100 ul ARIGO
anti-RIPK1 / RIP1 antibody ARG56458 50 ug ARIGO
anti-RIPK1 / RIP1 antibody ARG40183 100 ul ARIGO
anti-RIPK1 / RIP1 antibody [7H10] ARG70027 50 ul ARIGO
anti-RIPK1 / RIP1 phospho (Ser161) antibody ARG66649 100 ul ARIGO
anti-RIPK1 / RIP1 phospho (Ser166) antibody [YJY-1-5] ARG66476 100 ul ARIGO
anti-RIPK1 / RIP1 phospho (Tyr384) antibody ARG66650 100 ul ARIGO
전체보기
Maker
ARIGO
Cat.No.
ARG62626
Product
anti-NCOA1 / SRC1 antibody [SRC01 (GT12)]
Size
0.5 ml
Qty
Data Sheet
Maker
ARIGO
Cat.No.
ARG64095
Product
anti-NR1H4 / Farnesoid X Receptor antibody
Size
100 ug
Qty
Data Sheet
Maker
ARIGO
Cat.No.
ARG59015
Product
anti-RALBP1 antibody
Size
50 ug
Qty
Data Sheet
Maker
ARIGO
Cat.No.
ARG58949
Product
anti-RALBP1 antibody
Size
100 ul
Qty
Data Sheet
Maker
ARIGO
Cat.No.
ARG59058
Product
anti-RALBP1 antibody
Size
100 ul
Qty
Data Sheet
Maker
ARIGO
Cat.No.
ARG64977
Product
anti-RIP140 antibody
Size
100 ug
Qty
Data Sheet
Maker
ARIGO
Cat.No.
ARG55746
Product
anti-RIPK1 / RIP1 antibody
Size
50 ug
Qty
Data Sheet
Maker
ARIGO
Cat.No.
ARG40301
Product
anti-RIPK1 / RIP1 antibody
Size
100 ul
Qty
Data Sheet
Maker
ARIGO
Cat.No.
ARG56458
Product
anti-RIPK1 / RIP1 antibody
Size
50 ug
Qty
Data Sheet
Maker
ARIGO
Cat.No.
ARG40183
Product
anti-RIPK1 / RIP1 antibody
Size
100 ul
Qty
Data Sheet
Maker
ARIGO
Cat.No.
ARG70027
Product
anti-RIPK1 / RIP1 antibody [7H10]
Size
50 ul
Qty
Data Sheet
Maker
ARIGO
Cat.No.
ARG66649
Product
anti-RIPK1 / RIP1 phospho (Ser161) antibody
Size
100 ul
Qty
Data Sheet
Maker
ARIGO
Cat.No.
ARG66476
Product
anti-RIPK1 / RIP1 phospho (Ser166) antibody [YJY-1-5]
Size
100 ul
Qty
Data Sheet
Maker
ARIGO
Cat.No.
ARG66650
Product
anti-RIPK1 / RIP1 phospho (Tyr384) antibody
Size
100 ul
Qty
Data Sheet
전체보기

추천제품

관련제품

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS
M1/M2/TAM Marker Antibody Panel ARG30333 1 kit ARIGO
Necrosome Antibody Panel ARG30344 1 kit ARIGO

자료

웨비나/Video

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제품 문의

 0.5 ml Elite Pre-stained Protein Ladder (2 x 0.25 ml) PAL-EPL-500 0.5ml 500
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Cat.No.
Product
Size
Qty
Data Sheet
MSDS

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