고마바이오텍(주)

로그인이 필요합니다.

Category 전체보기
전기영동 > 단백질 전기영동 전기영동 > 헥산 전기영동
Cat. No.전체보기

검색 결과가 없습니다.

Product전체보기

검색 결과가 없습니다.

Brand전체보기

검색 결과가 없습니다.

제품 상세
Angiogenesis Activators & Inhibitors 이미지

Angiogenesis Activators & Inhibitors

Angiogenesis inhibitor (혈관신생억제제), Matrix metalloproteases (matrix metalloproteinase, MMPs)등을 포함한 Angiogenesis 연구 관련 inhibitor를 소개합니다.

프린트 제품 문의

Angiogenesis란? 

 

  • Angiogenesis는 Neovascularization (신생혈관)이라고도 하며, 새로운 혈관을 형성하는 과정입니다. 
  • 성장과 발육, 동맥, 정맥, 혈관, 모세관등의 형성에 기본적으로 필요한 과정이지만, 암세포가 스스로 성장하기 위해 angiogenesis를 자극하여 blood 공급을 유도하므로, 암 연구에도 매우 중요한 표적이 됩니다. 
  • 종양이 성장함에 따라 세포는 산소가 결핍되어 전사 인자인 저산소증 유도 인자-1(HIF-1)의 발현을 유도하여 다양한 혈관신생 인자의 발현을 유도하므로, 혈관신생억제제는 현재 암연구의 촛점입니다. 
  • 관절염의 경우에도 저산소 환경이 혈관신생을 촉진하여 확장된 조직에 영양분의 공급을 위해 새로운 혈관을 생성합니다. 
  • 반면, 뇌졸중, 심혈관, 당뇨병등과 같은 심근허혈, 말초혈관 질환에는 혈관신생을 촉진함으로서 질환 치료의 타겟으로 연구되기도 합니다. 

  Tumor vascularization



주요 제품 

Antiangiogenic Inhibitors
Cat. No. Product  Activity
5121 3PO PFKFB3 inhibitor; antiangiogenic
5617 AZD 1480 Potent and selective JAK2 inhibitor; antiangiogenic
4706 Borrelidin Antiangiogenic; inhibits threonyl-tRNA synthetase
5029 CHC Monocarboxylic acid transport (MCT) inhibitor; displays anti-angiogenic activities
1629 Herbimycin A Antiangiogenic. Inhibits Src family kinases and Hsp90
5981 Itraconazole SMO antagonist; antiangiogenic
5260 KG 5 Antiangiogenic; PDGFRβ, B-Raf, c-Raf, FLT3 and KIT inhibitor
6305 Lenalidomide Angiogenesis inhibitor; also TNF-α inhibitor and cereblon binder
4664 Obtustatin Potent and selective α1β1 inhibitor; antiangiogenic
2710 OGT 2115 Antiangiogenic. Heparanase inhibitor
6302 Pomalidomide Antiangiogenic; also TNF-α inhibitor and cereblon ubiquitination inhibitor
2954 PX 12 Thioredoxin-1 inhibitor; attenuates expression of HIF-1α
1418 Resveratrol Cyclooxygenase inhbitor
6187 SK 216 Angiogenesis inhibitor; Also PAI-1 inhibitor
6498 TASP 0277308 Potent and selective S1P1 receptor antagonist; inhibits angiogenesis
0652 Thalidomide Antiangiogenic; also inhibits TNF-α synthesis
1098 Tranilast Antiangiogenic
Matrix Metalloprotease Inhibitors
Cat. No. Product  Activity
2622 ARP 101 Inhibitor of MMP-2
2961 Batimastat Potent, broad spectrum MMP inhibitor
2632 CL 82198 hydrochloride Selective inhibitor of MMP-13
3807 Disulfiram Inhibits expression of MMP-2 and MMP-9; displays a range of other activities
4090 Doxycycline hyclate Broad-spectrum MMP inhibitor; tetracycline derivative
2983 GM 6001 Broad spectrum MMP inhibitor
7030 GW 280264X Potent ADAM10 and ADAM17 endopeptidase nhibitor
6439 JNJ 0966 Pro-MMP9 activation inhibitor
2631 Marimastat Broad spectrum MMP inhibitor
3268 Minocycline hydrochloride Inhibitor of MMP activity
4902 NSC 405020 Inhibitor of MT1-MMP; antitumor
2520 PD 166793 Broad spectrum MMP inhibitor
6088 SB 3CT High affinity and selective MMP2 inhibitor
4775 SD 2590 hydrochloride Potent MMP inhibitor
6134 T 26c disodium salt Highly potent and selective MMP13 inhibitor
5523 TAPI 0 ADAM-17 (TACE) and MMP inhibitor
6162 TAPI 1 ADAM-17 (TACE) and MMP inhibitor
6013 TAPI 2 ADAM-17 (TACE) and MMP inhibitor
2900 UK 370106 Highly selective MMP-3 and MMP-12 inhibitor
4188 UK 383367 Potent and selective BMP-1 (PCP) inhibitor
2633 WAY 170523 Potent and selective inhibitor of MMP-13
Hypoxia Inducible Factor (HIF) Inhibitors
Cat. No. Product  Activity
5953 Adaptaquin HIF-prolyl hydroxylase-2 (PHD2) inhibitor; antioxidant
4705 Chetomin Blocks interaction of HIF-1α, HIF-2α and STAT2 with CBP/p300
6157 cis VH 298 Negative control for VH 298
5764 Deferoxamine mesylate Hypoxia mimetic; also iron chelator
4408 DMOG Inhibitor of hypoxia-inducible factor α (HIF-α) prolyl hydroxylase (HIF-PH)
5520 Echinomycin Highly potent and selective HIF-1α inhibitor
7287 FAM-DEALA-Hyp-YIPD Fluorescent HIF-1α peptide
7452 FAM-DEALAHypYIPMDDDFQLRSF Fluorescent HIF-1α peptide
6653 FM19G11 HIF α-subunit inhibitor
5655 GN 44028 Potent HIF-1α inhibitor
4451 IOX 2 Potent, selective HIF-1α prolyl hydroxylase-2 (PHD2) inhibitor
4324 KC7F2 HIF-1α inhibitor; down-regulates HIF-1α protein synthesis
6322 LW 6 HIF-1α inhibitor; inhibits cellular accumulation of HIF-1α; also malate dehydrogenase-2 inhibitor
2954 PX 12 Thioredoxin-1 inhibitor; attenuates expression of HIF-1α
5582 TAT-cyclo-CLLFVY Selective HIF-1 dimerization inhibitor
5243 TC-S 7009 High affinity and selective HIF-2α inhibitor
7774 VH 032  Inhibitor of VHL; blocks interaction of VHL and HIF-α
6156 VH 298 High-affinity inhibitor of VHL; blocks interaction of VHL and HIF-α

주문정보

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS
3PO (10 mg) 5121 10 mg TOCRIS
3PO (50 mg) 5121 50 mg TOCRIS
ARP 101 (5 mg) 2622 5 mg TOCRIS
AV 412 (10 mg) 4397 10 mg TOCRIS
AZD 1480 (10 mg) 5617 10 mg TOCRIS
Batimastat (1 mg) 2961 1 mg TOCRIS
Batimastat (10 mg) 2961 10 mg TOCRIS
CHC (50 mg) 5029 50 mg TOCRIS
cis VH 298 (10 MG) 6157 10 mg TOCRIS
CL 82198 hydrochloride (10 mg) 2632 10 mg TOCRIS
CL 82198 hydrochloride (50 mg) 2632 50 mg TOCRIS
CP 724714 (10 mg) 5973 10 mg TOCRIS
CP 724714 (50 mg) 5973 50 mg TOCRIS
Deferoxamine mesylate (50 mg) 5764 50 mg TOCRIS
Doxycycline hyclate (50 mg) 4090 50 mg TOCRIS
Echinomycin (1 mg) 5520 1 mg TOCRIS
FM19G11 (25 MG) 6653 25 mg TOCRIS
FM19G11 (5 MG) 6653 5 mg TOCRIS
GM 6001 (10 mg) 2983 10 mg TOCRIS
GN 44028 (10 mg) 5655 10 mg TOCRIS
GW 280264X 7030 10 mg TOCRIS
GW 280264X 7030 50 mg TOCRIS
JNJ 0966 (10 MG) 6439 10 mg TOCRIS
JNJ 0966 (50 MG) 6439 50 mg TOCRIS
KC7F2 (10 mg) 4324 10 mg TOCRIS
KC7F2 (50 mg) 4324 50 mg TOCRIS
LW 6 (10 MG) 6322 10 mg TOCRIS
LW 6 (50 MG) 6322 50 mg TOCRIS
Marimastat (1 mg) 2631 1 mg TOCRIS
Marimastat (10 mg) 2631 10 mg TOCRIS
Minocycline hydrochloride (50 mg) 3268 50 mg TOCRIS
MS 154 (5mg) 7395 5 mg TOCRIS
MS 154N (5mg) 7396 5 mg TOCRIS
MS 39 (5 mg) 7397 5 mg TOCRIS
MS 39N (5mg) 7398 5 mg TOCRIS
Obtustatin (100 ug) 4664 100 ug TOCRIS
OGT 2115 (1 mg) 2710 1 mg TOCRIS
OGT 2115 (10 mg) 2710 10 mg TOCRIS
PD 166793 (10 mg) 2520 10 mg TOCRIS
PD 166793 (50 mg) 2520 50 mg TOCRIS
Pomalidomide (50 MG) 6302 50 mg TOCRIS
PX-12 11-079 25 mg PROSCI
SB 3CT (10 MG) 6088 10 mg TOCRIS
SD 2590 hydrochloride (10 mg) 4775 10 mg TOCRIS
SD 2590 hydrochloride (50 mg) 4775 50 mg TOCRIS
SJF 1521 (5 MG) 7261 5 mg TOCRIS
SJF 1528 (5 MG) 7262 5 mg TOCRIS
SK 216 (10 MG) 6187 10 mg TOCRIS
SK 216 (50 MG) 6187 50 mg TOCRIS
TAPI 0 (1 MG) 5523 1 mg TOCRIS
전체보기
Maker
TOCRIS
Cat.No.
5121
Product
3PO (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5121
Product
3PO (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
2622
Product
ARP 101 (5 mg)
Size
5 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4397
Product
AV 412 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5617
Product
AZD 1480 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
2961
Product
Batimastat (1 mg)
Size
1 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
2961
Product
Batimastat (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5029
Product
CHC (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6157
Product
cis VH 298 (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
2632
Product
CL 82198 hydrochloride (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
2632
Product
CL 82198 hydrochloride (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5973
Product
CP 724714 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5973
Product
CP 724714 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5764
Product
Deferoxamine mesylate (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4090
Product
Doxycycline hyclate (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5520
Product
Echinomycin (1 mg)
Size
1 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6653
Product
FM19G11 (25 MG)
Size
25 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6653
Product
FM19G11 (5 MG)
Size
5 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
2983
Product
GM 6001 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5655
Product
GN 44028 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7030
Product
GW 280264X
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7030
Product
GW 280264X
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6439
Product
JNJ 0966 (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6439
Product
JNJ 0966 (50 MG)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4324
Product
KC7F2 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4324
Product
KC7F2 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6322
Product
LW 6 (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6322
Product
LW 6 (50 MG)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
2631
Product
Marimastat (1 mg)
Size
1 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
2631
Product
Marimastat (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3268
Product
Minocycline hydrochloride (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7395
Product
MS 154 (5mg)
Size
5 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7396
Product
MS 154N (5mg)
Size
5 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7397
Product
MS 39 (5 mg)
Size
5 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7398
Product
MS 39N (5mg)
Size
5 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4664
Product
Obtustatin (100 ug)
Size
100 ug
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
2710
Product
OGT 2115 (1 mg)
Size
1 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
2710
Product
OGT 2115 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
2520
Product
PD 166793 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
2520
Product
PD 166793 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6302
Product
Pomalidomide (50 MG)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
PROSCI
Cat.No.
11-079
Product
PX-12
Size
25 mg
Qty
Data Sheet
Maker
TOCRIS
Cat.No.
6088
Product
SB 3CT (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4775
Product
SD 2590 hydrochloride (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4775
Product
SD 2590 hydrochloride (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7261
Product
SJF 1521 (5 MG)
Size
5 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7262
Product
SJF 1528 (5 MG)
Size
5 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6187
Product
SK 216 (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6187
Product
SK 216 (50 MG)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5523
Product
TAPI 0 (1 MG)
Size
1 mg
Qty
Data Sheet
MSDS
전체보기

추천제품

관련제품

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS

자료

  • Cancer Research Product Guide

    Cancer Research Product Guide 이미지

    [TOCRIS]

    Cancer 연구에 관련된 small molecule 정보가 수록되어 있습니다.

  • Angiogenesis in Cancer Poster

    Angiogenesis in Cancer Poster 이미지

    [TOCRIS]

    Cancer에서의 Angiogenesis pathway poster 입니다.

  • Tumor microenvironment (TME)

    Tumor microenvironment (TME) 이미지

    [ARIGO]

    종양미세환경과 관련된 marker와 pathway에 대한 포스터 입니다.

  • Inhibitor Book Vol.4

    Inhibitor Book Vol.4 이미지

    고마뉴스 자료신청 [KOMA]

    다양한 Disease 및 pathway 에 관련된 inhibitor 자료 입니다.

웨비나/Video

TOP

제품 문의

 0.5 ml Elite Pre-stained Protein Ladder (2 x 0.25 ml) PAL-EPL-500 0.5ml 500
Maker
Cat.No.
Product
Size
Qty
Data Sheet
MSDS

로그인

로그인