고마바이오텍(주)

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제품 상세

Antibody

6.5 - 270 kDa 범위를 커버하는 3가지 컬러 밴드를 포함하며,
최대 100%까지의 transfer 효과를 개런티하는 Prestained protein ladder를 소개합니다.

프린트 제품 문의

OxiSelect™ Advanced Glycation End Product (AGE) Competitive ELISA Kit (#STA-817)

 

  • AGE conjugate preabsorbed ELISA plate와 anti-AGE 항체를 이용하여 샘플내 존재하는 AGE 부산물의 양을 검출합니다. 
  • AGE-BSA standard curve 대비 샘플내 존재하는 AGE protein adducts를 정량 합니다. (competitive method)



OxiSelect™ Nε -(carboxyethyl) lysine (CEL) Competitive ELISA Kit (#STA-813)


  • AGE 구조를 이루는 Nε-(carboxyethyl) lysine (CEL)의 양을 측정합니다. 
  • CEL conjugate preabsorbed ELISA plate와 anti-CEL 항체를 이용하여 샘플내 존재하는 CEL 양을 검출합니다. 
  • CEL-BSA standard curve 대비 샘플내 존재하는 CEL을 정량 합니다. (competitive method)
  • Nε-(carboxymethyl)lysine (CML) 과 교차반응이 없습니다. 



OxiSelect™ N-epsilon-(Carboxymethyl) Lysine (CML) Competitive ELISA Kit (#STA-816)

  • AGE 구조를 이루는 Nε-(carboxymethyl)lysine (CML)의 양을 측정합니다. 
  • CML conjugate preabsorbed ELISA plate와 anti-CML 항체를 이용하여 샘플내 존재하는 CML 양을 검출합니다. 
  • CML-BSA standard curve 대비 샘플내 존재하는 CML을 정량 합니다. (competitive method)




OxiSelect™ Methylglyoxal (MG) Competitive ELISA Kit (#STA-811)


  • Methylglyoxal (MG)는 AGE의 구조 변이체로 단백질의 arginine, lysine, cysteine 잔기와 반응하여 생성되며, 당뇨병과 같은 다양한 병리학적 기전에 관여합니다. 
  • MG conjugate preabsorbed ELISA plate와 anti-MG 항체를 이용하여 샘플내 존재하는 MG 양을 검출합니다. 
  • MG-BSA standard curve 대비 샘플내 존재하는 MG를 정량 합니다. (competitive method)

 

 

 

사용 논문

 

 

STA-817 　
    1. Waditee-Sirisattha, R. & Kageyama, H. (2021). Protective effects of mycosporine-like amino acid-containing emulsions on UV-treated mouse ear tissue from the viewpoints of antioxidation and antiglycation. J Photochem Photobiol B. 223:112296. doi: 10.1016/j.jphotobiol.2021.112296.
    2. Zhu, J. et al. (2021). An evaluation of the growth, blood biochemistry, hepatic glucose metabolism and hepatocyte apoptosis in the genetically improved farmed tilapia Oreochromis niloticus fed diets with distinct protein to corn starch ratios. Aquac Res. doi: 10.1111/are.15521.
    3. Pramanik, S. et al. (2021). Efficacy and Cost-Effectiveness of Anti-VEGF for Treating Diabetic Retinopathy in the Indian Population. Clin Ophthalmol. 15:3341-3350. doi: 10.2147/OPTH.S317771.
    4. Darabseh, M.Z. et al. (2021). Fourteen days of smoking cessation improves muscle fatigue resistance and reverses markers of systemic inflammation. Sci Rep. 11(1):12286. doi: 10.1038/s41598-021-91510-x.
    5. Lederle, M. et al. (2021). Continuous optical in-line glucose monitoring and control in CHO cultures contributes to enhanced metabolic efficiency while maintaining darbepoetin alfa product quality. Biotechnol J. doi: 10.1002/biot.202100088.
    6. Ahmad, S. et al. (2021). Gold Nanoparticle-Bioconjugated Aminoguanidine Inhibits Glycation Reaction: An In Vivo Study in a Diabetic Animal Model. Biomed Res Int. doi: 10.1155/2021/5591851.
    7. Czubak-Prowizor, K. et al. (2021). Increased Oxidative Stress in Acute Myeloid Leukemia Patients after Red Blood Cell Transfusion, but Not Platelet Transfusion, Results Mainly from the Oxidative/Nitrative Protein Damage: An Exploratory Study. J Clin Med. 10(7):1349. doi: 10.3390/jcm10071349.
    8. Jimenez, A.G. (2021). Plasma Concentration of Advanced Glycation End-Products From Wild Canids and Domestic Dogs Does Not Change With Age or Across Body Masses. Front. Vet. Sci. doi: 10.3389/fvets.2021.637132.
    9. Bai, R. et al. (2021). Design and methodology of a randomized crossover trial to test the effect of low and high dAGE diets on metabolic risk factors and inflammatory markers among overweight and centrally obese Asian Indian adults. J Diabetol. 12(1):46-57. doi: 10.4103/jod.jod_22_20.
    10.  Chan, K.C. et al. (2020). Effects of fermented red bean extract on nephropathy in streptozocin-induced diabetic rats. Food Nutr Res. doi: 10.29219/fnr.v64.4272.
    11. Al-Attar, R. et al. (2020). RAGE against the stress: mitochondrial suppression in hypometabolic hearts. Gene. doi: 10.1016/j.gene.2020.145039.
    12. Horikawa, T. et al. (2020). Differences in the mechanism of type 1 and type 2 diabetes-induced skin dryness by using model mice. Int J Med Sci. 18(2):474-481. doi: 10.7150/ijms.50764.
    13. Elmazoglu, Z. et al. (2020). TRL4, RAGE, and p-JNK/JNK mediated inflammatory aggression in osteoathritic human chondrocytes are counteracted by redox-sensitive phenolic olive compounds: Comparison with ibuprofen. J Tissue Eng Regen Med. doi: 10.1002/term.3138.
    14. Yassa, N.W. et al. (2020). Ipriflavone and Ipriflavone loaded albumin nanoparticles reverse lipopolysaccharide induced neuroinflammation in rats. PLoS One. 15(8):e0237929. doi: 10.1371/journal.pone.0237929.
    15. Cheng, H.S. et al. (2020). Pleiotrosepic ameliorative effects of ellagitannin geraniin against metabolic syndrome induced by high-fat diet in rats. Nutrition. doi: 10.1016/j.nut.2020.110973.
    16. Park, E. et al. (2020). Jaceosidin Ameliorates Insulin Resistance and Kidney Dysfunction by Enhancing Insulin Receptor Signaling and the Antioxidant Defense System in Type 2 Diabetic Mice. J Med Food. doi: 10.1089/jmf.2020.4739.
    17. Menini, S. et al. (2020). Diabetes promotes invasive pancreatic cancer by increasing systemic and tumour carbonyl stress in KrasG12D/+ mice. J Exp Clin Cancer Res. 39(1):152. doi: 10.1186/s13046-020-01665-0.
    18. Hong, J.Y. et al. (2020). in vivo Quantitative Analysis of Advanced Glycation End Products in Atopic Dermatitis - Possible Culprit for the Comorbidities? Exp Dermatol. doi: 10.1111/exd.14167.
    19. Mohamed, A.H. et al. (2020). Antidiabetic and anti-inflammatory effects of two Fabaceae extracts against streptozotocin induced diabetic impairment in male rats. World Journal of Advanced Research and Reviews. 06(03):012-029. doi: 10.30574/wjarr.2020.6.3.0162.
    20. Tang, S. et al. (2020). Structure–activity relationship and hypoglycemic activity of tricyclic matrines with advantage of treating diabetic nephropathy. Eur J Med Chem. doi: 10.1016/j.ejmech.2020.112315.
    21. Biró, A. et al. (2020). Allithiamine Alleviates Hyperglycaemia-Induced Endothelial Dysfunction. Nutrients. 12(6):E1690. doi: 10.3390/nu12061690.
    22. Gryszczyńska, B. et al. (2020). Selected Atherosclerosis-Related Diseases May Differentially Affect the Relationship between Plasma Advanced Glycation End Products, Receptor sRAGE, and Uric Acid. J Clin Med. 9(5). pii: E1416. doi: 10.3390/jcm9051416.
    23. Moemen, L.A. et al. (2020). Role of advanced glycation end products and sorbitol dehydrogenase in the pathogenesis of diabetic retinopathy. Bull Natl Res Cent. 44:58 doi: 10.1186/s42269-020-00304-0.
    24. Chen, S.H. et al. (2020). Iron and Advanced Glycation End Products: Emerging Role of Iron in Androgen Deficiency in Obesity. Antioxidants. 9:261. doi: 10.3390/antiox9030261.
    25. Biruete, A. et al. (2020). Adverse Effects of Autoclaved Diets on the Progression of Chronic Kidney Disease and Chronic Kidney Disease-Mineral Bone Disorder in Rats. Am J Nephrol. doi: 10.1159/000506729.
    26. Wojnar, W. et al. (2020). Chrysin Reduces Oxidative Stress but Does Not Affect Polyol Pathway in the Lenses of Type 1 Diabetic Rats. Antioxidants. 9:160. doi: 10.3390/antiox9020160.
    27. Shimizu, Y. et al. (2020). Role of DJ‐1 in Modulating Glycative Stress in Heart Failure. J Am Heart Assoc. 9(4). doi: 10.1161/jaha.119.014691.
    28. Zhang, I.Y. et al. (2020). Local and Systemic Immune Dysregulation Alters Glioma Growth in Hyperglycemic Mice. Clin Cancer Res. pii: clincanres.2520.2019. doi: 10.1158/1078-0432.CCR-19-2520.
    29. Kundu, A. et al. (2020). Protective effect of EX-527 against high-fat diet-induced diabetic nephropathy in Zucker rats. Toxicol Appl Pharmacol. doi: 10.1016/j.taap.2020.114899.
    30. Hosokawa, K. et al. (2019). Ipragliflozin Ameliorates Endoplasmic Reticulum Stress and Apoptosis through Preventing Ectopic Lipid Deposition in Renal Tubules. Int J Mol Sci. 21(1). pii: E190. doi: 10.3390/ijms21010190.
STA-813 　
    1. Drygalski, K. et al. (2021). Phloroglucinol prevents albumin glycation as well as diminishes ROS production, glycooxidative damage, nitrosative stress and inflammation in hepatocytes treated with high glucose. Biomed Pharmacother. 142:111958. doi: 10.1016/j.biopha.2021.111958.
    2. Kaburagi, T. et al. (2019). Low-Carbohydrate Diet Inhibits Different Advanced Glycation End Products in Kidney Depending on Lipid Composition but Causes Adverse Morphological Changes in a Non-Obese Model Mice. Nutrients. 11(11). pii: E2801. doi: 10.3390/nu11112801.
    3. Nakamura, T. et al. (2019). Poorly controlled type 2 diabetes with no progression of diabetes-related complications and low levels of advanced glycation end products: A Case report. Medicine (Baltimore). 98(30):e16573. doi: 10.1097/MD.0000000000016573.
    4. Li, C.T. et al. (2018). Effects of glycation on human γd-crystallin proteins by different glycation-inducing agents. Int J Biol Macromol. 118(Pt A):442-451. doi: 10.1016/j.ijbiomac.2018.06.108.
    5. Cannizzaro, L. et al. (2017). Regulatory landscape of AGE-RAGE-oxidative stress axis and its modulation by PPARγ activation in high fructose diet-induced metabolic syndrome. Nutr Metab (Lond). 14:5. doi: 10.1186/s12986-016-0149-z.
    6. Morgan, P. E. et al. (2014). Perturbation of human coronary artery endothelial cell redox state and NADPH generation by methylglyoxal. PLoS One. 9:e86564.
STA-816 　
    1. Shin, S. et al. (2021). Anti-glycation activities of methyl gallate in vitro and in human explants. J Cosmet Dermatol. doi: 10.1111/jocd.14406.
    2. Mahmoud, A.M. & Ali, M.M. (2021) High Glucose and Advanced Glycation End Products Induce CD147-Mediated MMP Activity in Human Adipocytes. Cells. 10(8):2098. doi: 10.3390/cells10082098.
    3. Lazzari, T.K. et al. (2021). Leptin and advanced glycation end products receptor (RAGE) in tuberculosis patients. PLoS One. 16(7):e0254198. doi: 10.1371/journal.pone.0254198.
    4. Ahmad, S. et al. (2021). Gold Nanoparticle-Bioconjugated Aminoguanidine Inhibits Glycation Reaction: An In Vivo Study in a Diabetic Animal Model. Biomed Res Int. doi: 10.1155/2021/5591851.
    5. Chiew, Y. et al. (2021). Tocotrienol-rich vitamin E from palm oil (Tocovid) and its effects in diabetes and diabetic retinopathy: a pilot phase II clinical trial. Asian J. Ophthalmol. 17(4):375-399. doi: 10.35119/asjoo.v17i4.698.
    6. Altomare, A. et al. (2021). In-Depth AGE and ALE Profiling of Human Albumin in Heart Failure: Ex Vivo Studies. Antioxidants (Basel). 10(3):358. doi: 10.3390/antiox10030358.
    7. Li, Y.Y. et al. (2021). Protective effects of dietary carnosine during in-vitro digestion of pork differing in fat content and cooking conditions. J Food Biochem. 45(2):e13624. doi: 10.1111/jfbc.13624.
    8. Chen, Z. et al. (2020). Association of carbamylated high-density lipoprotein with coronary artery disease in type 2 diabetes mellitus: carbamylated high-density lipoprotein of patients promotes monocyte adhesion. J Transl Med. 18(1):460. doi: 10.1186/s12967-020-02623-2.
    9. Merhi, Z. et al. (2020). Perinatal Exposure to High Dietary Advanced Glycation End-Products Affects the Reproductive System in Female Offspring in Mice. Mol Hum Reprod. doi: 10.1093/molehr/gaaa046.
    10. Gutierrez-Mariscal, F.M. et al. (2020). Reduction in Circulating Advanced Glycation End Products by Mediterranean Diet is Associated with Increased Likelihood of type 2 Diabetes Remission in Patients with Coronary Heart Disease: From the Cordioprev Study. Mol Nutr Food Res. doi: 10.1002/mnfr.201901290.
    11. Thornton, K. et al. (2020). Dietary Advanced Glycation End Products (AGEs) could alter ovarian function in mice. Mol Cell Endocrinol. doi: 10.1016/j.mce.2020.110826.
    12. Hernández, C. et al. (2020). The Usefulness of Serum Biomarkers in the Early Stages of Diabetic Retinopathy: Results of the EUROCONDOR Clinical Trial. J Clin Med. 9(4). pii: E1233. doi: 10.3390/jcm9041233.
    13. Velayoudom-Cephise, F.L. et al. (2020). Receptor For Advanced Glycated End Products Modulates Oxidative Stress And Mitochondrial Function In The Soleus Muscle Of High Fat Fed Mice. Appl Physiol Nutr Metab. doi: 10.1139/apnm-2019-0936.
    14. Chen, S.H. et al. (2020). Iron and Advanced Glycation End Products: Emerging Role of Iron in Androgen Deficiency in Obesity. Antioxidants. 9:261. doi: 10.3390/antiox9030261.
    15. Shimizu, Y. et al. (2020). Role of DJ‐1 in Modulating Glycative Stress in Heart Failure. J Am Heart Assoc. 9(4). doi: 10.1161/jaha.119.014691.
    16. de la Cruz-Ares, S. et al. (2020). Endothelial Dysfunction and Advanced Glycation End Products in Patients with Newly Diagnosed Versus Established Diabetes: From the CORDIOPREV Study. Nutrients. 12(1). pii: E238. doi: 10.3390/nu12010238.
    17. Lee, J. et al. (2019). Mitochondrial carnitine palmitoyltransferase 2 is involved in Nε-(carboxymethyl)-lysine-mediated diabetic nephropathy. Pharmacol Res. doi: 10.1016/j.phrs.2019.104600.
    18. Kaburagi, T. et al. (2019). Low-Carbohydrate Diet Inhibits Different Advanced Glycation End Products in Kidney Depending on Lipid Composition but Causes Adverse Morphological Changes in a Non-Obese Model Mice. Nutrients. 11(11). pii: E2801. doi: 10.3390/nu11112801.
    19. Yang, J. et al. (2019). Neutrophil-derived advanced glycation end products-Nε-(carboxymethyl) lysine promotes RIP3-mediated myocardial necroptosis via RAGE and exacerbates myocardial ischemia/reperfusion injury. FASEB J. doi: 10.1096/fj.201900115RR.
    20. Ndidi, U.S. et al. (2019). Effect of N(Epsilon)-(carboxymethyl)lysine on Laboratory Parameters and Its Association with βS Haplotype in Children with Sickle Cell Anemia. Disease Markers. doi: 10.1155/2019/1580485.
    21. Ferron, A.J.T. et al. (2019). Protective Effect of Tomato-Oleoresin Supplementation on Oxidative Injury Recoveries Cardiac Function by Improving β-Adrenergic Response in a Diet-Obesity Induced Model. Antioxidants (Basel). 8(9). pii: E368. doi: 10.3390/antiox8090368.
    22. da Silva, L.F. et al. (2019). Advanced glycation end products (AGE) and receptor for AGE (RAGE) in patients with active tuberculosis, and their relationship between food intake and nutritional status. PLoS One. 14(3):e0213991. doi: 10.1371/journal.pone.0213991.
    23. Chen, Y. et al. (2019). Dietary Early Glycation Products Promote the Growth of Prostate Tumors More than Advanced Glycation End-Products through Modulation of Macrophage Polarization. Mol Nutr Food Res. 63(4):e1800885. doi: 10.1002/mnfr.201800885.
    24. Rosa Martha, P.G. et al. (2018). Ursane derivatives isolated from leaves of Hylocereus undatus inhibit glycation at multiple stages. Chin J Nat Med. 16(11):856-865. doi: 10.1016/S1875-5364(18)30127-4.
    25. Balansin Rigon, R. et al. (2018). Ultrastructural and Molecular Analysis of Ribose-Induced Glycated Reconstructed Human Skin. Int J Mol Sci. 19(11). pii: E3521. doi: 10.3390/ijms19113521.
    26. Tan, S.M.Q. et al. (2018). Tocotrienol-Rich Vitamin E from Palm Oil (Tocovid) and Its Effects in Diabetes and Diabetic Nephropathy: A Pilot Phase II Clinical Trial. Nutrients. 10(9). pii: E1315. doi: 10.3390/nu10091315.
    27. Gutierrez, R. M. P. et al. (2018). Silver Nanoparticles Synthesized Using Eysenhardtia polystachya and Assessment of the Inhibition of Glycation in Multiple Stages In Vitro and in the Zebrafish Model. Journal of Cluster Science. doi: 10.1007/s10876-018-1448-5.
    28. Thilavech, T. et al. (2018). Cyanidin-3-rutinoside alleviates methylglyoxal-induced cardiovascular abnormalities in the rats. Journal of Functional Foods. 49:258–266. doi:10.1016/j.jff.2018.08.034.
    29. Menini, S. et al. (2018). The advanced glycation end-product Nϵ -carboxymethyllysine promotes progression of pancreatic cancer: implications for diabetes-associated risk and its prevention. J Pathol. 245(2):197-208. doi: 10.1002/path.5072.
    30. Hu, X. et al. (2018). Protection by dimethyl fumarate against diabetic cardiomyopathy in type 1 diabetic mice likely via activation of nuclear factor erythroid-2 related factor 2. Toxicol Lett. 287:131-141. doi: 10.1016/j.toxlet.2018.01.020.
STA-811 　
    1. Oliveira, A.L. et al. (2021). Metformin abrogates the voiding dysfunction induced by prolonged methylglyoxal intake. Eur J Pharmacol. 910:174502. doi: 10.1016/j.ejphar.2021.174502.
    2. Kim, M. et al. (2021). Ishige okamurae Ameliorates Methylglyoxal-Induced Nephrotoxicity via Reducing Oxidative Stress, RAGE Protein Expression, and Modulating MAPK, Nrf2/ARE Signaling Pathway in Mouse Glomerular Mesangial Cells. Foods. 10(9):2000. doi: 10.3390/foods10092000.
    3. Ragno, V.M. et al. (2021). Morphometric, metabolic, and inflammatory markers across a cohort of client-owned horses and ponies on the insulin dysregulation spectrum. J Equine Vet Sci. doi: 10.1016/j.jevs.2021.103715.
    4. Suh, K.S. et al. (2021). Protective effects of sciadopitysin against methylglyoxal-induced degeneration in neuronal SK-N-MC cells. J Appl Toxicol. doi: 10.1002/jat.4211.
    5. Gutierrez-Mariscal, F.M. et al. (2020). Reduction in Circulating Advanced Glycation End Products by Mediterranean Diet is Associated with Increased Likelihood of type 2 Diabetes Remission in Patients with Coronary Heart Disease: From the Cordioprev Study. Mol Nutr Food Res. doi: 10.1002/mnfr.201901290.
    6. Li, J. et al. (2020). Renal protective effects of empagliflozin via inhibition of EMT and aberrant glycolysis in proximal tubules. JCI Insight. pii: 129034. doi: 10.1172/jci.insight.129034.
    7. Piuri, G. et al. (2020). Methylglyoxal, Glycated Albumin, PAF, and TNF-α: Possible Inflammatory and Metabolic Biomarkers for Management of Gestational Diabetes. Nutrients. 12:479. doi: 10.3390/nu12020479.
    8. Shimizu, Y. et al. (2020). Role of DJ‐1 in Modulating Glycative Stress in Heart Failure. J Am Heart Assoc. 9(4). doi: 10.1161/jaha.119.014691.
    9. de la Cruz-Ares, S. et al. (2020). Endothelial Dysfunction and Advanced Glycation End Products in Patients with Newly Diagnosed Versus Established Diabetes: From the CORDIOPREV Study. Nutrients. 12(1). pii: E238. doi: 10.3390/nu12010238.
    10. Liu, C. et al. (2020). Inhibition of thioredoxin 2 by intracellular methylglyoxal accumulation leads to mitochondrial dysfunction and apoptosis in INS-1 cells. Endocrine. doi: 10.1007/s12020-020-02191-x.
    11. Egawa, T. et al. (2019). The Protective Effect of Brazilian Propolis against Glycation Stress in Mouse Skeletal Muscle. Foods. 8(10). pii: E439. doi: 10.3390/foods8100439.
    12. Do, M.H. et al. (2019). Schizonepeta tenuifolia reduces methylglyoxal-induced cytotoxicity and oxidative stress in mesangial cells. J Funct Foods. doi: 10.1016/j.jff.2019.103531.
    13. Nakamura, T. et al. (2019). Poorly controlled type 2 diabetes with no progression of diabetes-related complications and low levels of advanced glycation end products: A Case report. Medicine (Baltimore). 98(30):e16573. doi: 10.1097/MD.0000000000016573.
    14. Griggs, R.B. et al. (2019). Methylglyoxal and a spinal TRPA1-AC1-Epac cascade facilitate pain in the db/db mouse model of type 2 diabetes. Neurobiol Dis. 127:76-86. doi: 10.1016/j.nbd.2019.02.019.
    15. Shamsaldeen, Y.A. et al. (2019). Dysfunction in nitric oxide synthesis in streptozotocin treated rat aorta and role of methylglyoxal. Eur J Pharmacol. 842:321-328. doi: 10.1016/j.ejphar.2018.10.056.
    16. Simón, L. et al. (2018). Olive oil addition to the high-fat diet reduces methylglyoxal (MG-H1) levels increased in hypercholesterolemic rabbits. Mediterranean Journal of Nutrition and Metabolism. doi: 10.3233/mnm-180229.
    17. Thompson, K. et al. (2018). Advanced glycation end (AGE) product modification of laminin downregulates Kir4.1 in retinal Müller cells. PLoS One. 13(2):e0193280. doi: 10.1371/journal.pone.0193280.
    18. Suh, K.S. et al. (2018). Cytoprotective effects of xanthohumol against methylglyoxal-induced cytotoxicity in MC3T3-E1 osteoblastic cells. J Appl Toxicol. 38:180–192. 
    19. Park, S. et al. (2017). Bariatric Surgery can Reduce Albuminuria in Patients with Severe Obesity and Normal Kidney Function by Reducing Systemic Inflammation. Obes Surg. doi: 10.1007/s11695-017-2940-y.
    20. Suh, K.S. et al. (2017). Magnolol protects pancreatic β-cells against methylglyoxal-induced cellular dysfunction. Chem Biol Interact. 277:101-109. doi: 10.1016/j.cbi.2017.09.014.
    21. Suh, K.S. et al. (2017). Limonene protects osteoblasts against methylglyoxal-derived adduct formation by regulating glyoxalase, oxidative stress, and mitochondrial function. Chem Biol Interact. 278:15-21. doi: 10.1016/j.cbi.2017.10.001.
    22. Suh, K.S. et al. (2017). Deoxyactein protects pancreatic β-cells against methylglyoxal-induced oxidative cell damage by the upregulation of mitochondrial biogenesis. Int. J. Mol. Med. doi:10.3892/ijmm.2017.3018.
    23. Nishimoto S, et al. (2017). Activation of Nrf2 attenuates carbonyl stress induced by methylglyoxal in human neuroblastoma cells: Increase in GSH levels is a critical event for the detoxification mechanism. Biochem Biophys Res Commun. doi: 10.1016/j.bbrc.2
    24. Lopez-Moreno, J. et al. (2016). Mediterranean diet supplemented with Coenzyme Q10 modulates the postprandial metabolism of advanced glycation end products in elderly men and women. J. Gerontol. A Biol. Sci. Med. Sci. doi:10.1093/gerona/glw214.
    25. Ueda, K. et al. (2016). Photodegradation of retinal bisretinoids in mouse models and implications for macular degeneration. Proc Natl Acad Sci U S A.  doi:10.1073/pnas.1524774113.
    26. Morgan, P. E. et al. (2014). Perturbation of human coronary artery endothelial cell redox state and NADPH generation by methylglyoxal. PLoS One. 9:e86564.

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 0.5 ml Elite Pre-stained Protein Ladder (2 x 0.25 ml) PAL-EPL-500 0.5ml 500
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