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[R&D Systems] Anti-Idiotype Antibodies | 항이디오타입 항체 이미지

[R&D Systems] Anti-Idiotype Antibodies | 항이디오타입 항체

Maker : R&D SYSTEMS

바이오시밀러 항체의 variable region에 특이적으로 결합하여 약동학 및 면역원성 연구에 사용되는 anti-idiotype antibody를 소개합니다.

프린트 제품 문의

특징


  • Anti-idiotype 항체는 다른 항체의 항원 결합 부위(가변영역, "이디오타입")를 인식하고 결합하는 항체입니다. 
  • 항체의 가변 부위에 특이적으로 결합하기 때문에, 약물동태학(pharmacokinetics) 및 면역원성(immunogenicity) 연구에서 유용한 도구로 사용됩니다.
  • Anti-idiotype 항체는 결합을 차단하는 항체(blocking)일 수도 있고 결합은 하지만 차단하지 않는 항체(non-blocking)일 수도 있습니다.
  • 특정 바이오시밀러 항체를 정확하게 인식할 수 있도록 특별히 설계되었습니다. 
  • 각 항체들은 유세포 분석, 결합억제, ELISA 등 다양한 방법을 통해 기능 검증 후 제공됩니다.  

Anti-Idiotype Antibodies


내부 테스트 항목

1. Bridging Assay 
Anti-idiotype 항체가 바이오시밀러 항체를 포획하고 검출하였음을 검증합니다. 


2. Flow Cytometry
세포 표면의 리간드에 결합한 바이오시밀러 항체에만 결합하고, 바이오시밀러 항체가 없을 경우에는 세포에 결합하지 않음을 확인합니다.



3. Binding Inhibition
Anti-idiotype 항체에 대한 isotype control을 함께 사용하여, 결합이 항이디오타입 항체에 의해서만 차단된다는 것을 확인합니다.


4. Direct ELISA
Direct ELISA는 Anti-idiotype 항체의 특이성을 평가하는 데 사용됩니다. 바이오시밀러 항체를 플레이트에 고정한 뒤, Anti-idiotype 항체를 이용하여 해당 바이오시밀러 항체를 검출합니다. 이 항체는 표적 바이오시밀러에만 반응하며, 다른 종류의 바이오시밀러 항체와는 결합하지 않습니다.

 

주문정보

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 350 MAb (Clone 2 FAB9616U-100UG 100 µg R&DSYSTEM
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 350 MAb (Clone 9 FAB9546U-100UG 100 µg R&DSYSTEM
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 405 MAb (Clone 2 FAB9616V-100UG 100 µg R&DSYSTEM
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 405 MAb (Clone 9 FAB9546V-100UG 100 µg R&DSYSTEM
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 488 MAb (Clone 2 FAB9616G-100UG 100 µg R&DSYSTEM
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 488 MAb (Clone 9 FAB9546G-100UG 100 µg R&DSYSTEM
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 532 MAb (Clone 2 FAB9616X-100UG 100 µg R&DSYSTEM
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 532 MAb (Clone 9 FAB9546X-100UG 100 µg R&DSYSTEM
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 594 MAb (Clone 2 FAB9616T-100UG 100 µg R&DSYSTEM
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 594 MAb (Clone 9 FAB9546T-100UG 100 µg R&DSYSTEM
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 647 MAb (Clone 2 FAB9616R-100UG 100 µg R&DSYSTEM
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 647 MAb (Clone 9 FAB9546R-100UG 100 µg R&DSYSTEM
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 700 MAb (Clone 2 FAB9616N-100UG 100 µg R&DSYSTEM
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 700 MAb (Clone 9 FAB9546N-100UG 100 µg R&DSYSTEM
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 750 MAb (Clone 2 FAB9616S-100UG 100 µg R&DSYSTEM
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 750 MAb (Clone 9 FAB9546S-100UG 100 µg R&DSYSTEM
Anti-Adalimumab (Anti-Idiotype) MAb (Clone 2235F) (25 ug) MAB9616-SP 25 ug R&D SYSTEMS
Anti-Adalimumab (Anti-Idiotype) MAb (Clone 972557) (100 ug) MAB9546-100 100 ug R&D SYSTEMS
Anti-Adalimumab (Anti-Idiotype) MAb (Clone 972557) (25 ug) MAB9546-SP 25 ug R&D SYSTEMS
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 350 MAb (Clone 2 FAB10180U-100UG 100 µg R&DSYSTEM
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 350 MAb (Clone 9 FAB9545U-100UG 100 µg R&DSYSTEM
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 405 MAb (Clone 2 FAB10180V-100UG 100 µg R&DSYSTEM
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 405 MAb (Clone 9 FAB9545V-100UG 100 µg R&DSYSTEM
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 488 MAb (Clone 2 FAB10180G-100UG 100 µg R&DSYSTEM
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 488 MAb (Clone 9 FAB9545G-100UG 100 µg R&DSYSTEM
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 532 MAb (Clone 2 FAB10180X-100UG 100 µg R&DSYSTEM
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 532 MAb (Clone 9 FAB9545X-100UG 100 µg R&DSYSTEM
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 594 MAb (Clone 2 FAB10180T-100UG 100 µg R&DSYSTEM
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 594 MAb (Clone 9 FAB9545T-100UG 100 µg R&DSYSTEM
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 647 MAb (Clone 2 FAB10180R-100UG 100 µg R&DSYSTEM
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 647 MAb (Clone 9 FAB9545R-100UG 100 µg R&DSYSTEM
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 700 MAb (Clone 2 FAB10180N-100UG 100 µg R&DSYSTEM
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 700 MAb (Clone 9 FAB9545N-100UG 100 µg R&DSYSTEM
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 750 MAb (Clone 2 FAB10180S-100UG 100 µg R&DSYSTEM
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 750 MAb (Clone 9 FAB9545S-100UG 100 µg R&DSYSTEM
Anti-Aducanumab (Anti-Idiotype) MAb (Clone 2374E) (25 ug) MAB10180-SP 25 ug R&D SYSTEMS
Anti-Aducanumab (Anti-Idiotype) MAb (Clone 975942) (100 ug) MAB9545-100 100 ug R&D SYSTEMS
Anti-Aducanumab (Anti-Idiotype) MAb (Clone 975942) (25 ug) MAB9545-SP 25 ug R&D SYSTEMS
Anti-Alemtuzumab (Anti-Idiotype) MAb (Clone 2499A) (100 ug) MAB10246-100 100 ug R&D SYSTEMS
Anti-Alemtuzumab (Anti-Idiotype) MAb (Clone 2499A) (25 ug) MAB10246-SP 25 ug R&D SYSTEMS
Anti-Brentuximab (Anti-Idiotype) Alexa Fluor 350 MAb (2262C) (100 ug) FAB9584U-100UG 100 ug R&D SYSTEMS
Anti-Brentuximab (Anti-Idiotype) Alexa Fluor 405 MAb (2262C) (100 ug) FAB9584V-100UG 100 ug R&D SYSTEMS
Anti-Brentuximab (Anti-Idiotype) Alexa Fluor 594 MAb (2262C) (100 ug) FAB9584T-100UG 100 ug R&D SYSTEMS
Anti-Brentuximab (Anti-Idiotype) Alexa Fluor 647 MAb (2262C) (100 ug) FAB9584R-100UG 100 ug R&D SYSTEMS
Anti-Brentuximab (Anti-Idiotype) Alexa Fluor 700 MAb (2262C) (100 ug) FAB9584N-100UG 100 ug R&D SYSTEMS
Anti-Brentuximab (Anti-Idiotype) Alexa Fluor 750 MAb (2262C) (100 ug) FAB9584S-100UG 100 ug R&D SYSTEMS
Anti-Brentuximab (Anti-Idiotype) MAb (Clone 2262C) (25 ug) MAB9584-SP 25 ug R&D SYSTEMS
Anti-Cetuximab (Anti-Idiotype) Alexa Fluor 350 MAb (2259C) (100 ug) FAB9626U-100UG 100 ug R&D SYSTEMS
Anti-Cetuximab (Anti-Idiotype) Alexa Fluor 405 MAb (2259C) (100 ug) FAB9626V-100UG 100 ug R&D SYSTEMS
Anti-Cetuximab (Anti-Idiotype) Alexa Fluor 488 MAb (2259C) (100 ug) FAB9626G-100UG 100 ug R&D SYSTEMS
전체보기
Maker
R&DSYSTEM
Cat.No.
FAB9616U-100UG
Product
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 350 MAb (Clone 2
Size
100 µg
Qty
Maker
R&DSYSTEM
Cat.No.
FAB9546U-100UG
Product
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 350 MAb (Clone 9
Size
100 µg
Qty
Maker
R&DSYSTEM
Cat.No.
FAB9616V-100UG
Product
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 405 MAb (Clone 2
Size
100 µg
Qty
Maker
R&DSYSTEM
Cat.No.
FAB9546V-100UG
Product
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 405 MAb (Clone 9
Size
100 µg
Qty
Maker
R&DSYSTEM
Cat.No.
FAB9616G-100UG
Product
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 488 MAb (Clone 2
Size
100 µg
Qty
Maker
R&DSYSTEM
Cat.No.
FAB9546G-100UG
Product
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 488 MAb (Clone 9
Size
100 µg
Qty
Maker
R&DSYSTEM
Cat.No.
FAB9616X-100UG
Product
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 532 MAb (Clone 2
Size
100 µg
Qty
Maker
R&DSYSTEM
Cat.No.
FAB9546X-100UG
Product
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 532 MAb (Clone 9
Size
100 µg
Qty
Maker
R&DSYSTEM
Cat.No.
FAB9616T-100UG
Product
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 594 MAb (Clone 2
Size
100 µg
Qty
Maker
R&DSYSTEM
Cat.No.
FAB9546T-100UG
Product
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 594 MAb (Clone 9
Size
100 µg
Qty
Maker
R&DSYSTEM
Cat.No.
FAB9616R-100UG
Product
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 647 MAb (Clone 2
Size
100 µg
Qty
Maker
R&DSYSTEM
Cat.No.
FAB9546R-100UG
Product
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 647 MAb (Clone 9
Size
100 µg
Qty
Maker
R&DSYSTEM
Cat.No.
FAB9616N-100UG
Product
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 700 MAb (Clone 2
Size
100 µg
Qty
Maker
R&DSYSTEM
Cat.No.
FAB9546N-100UG
Product
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 700 MAb (Clone 9
Size
100 µg
Qty
Maker
R&DSYSTEM
Cat.No.
FAB9616S-100UG
Product
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 750 MAb (Clone 2
Size
100 µg
Qty
Maker
R&DSYSTEM
Cat.No.
FAB9546S-100UG
Product
Anti-Adalimumab (Anti-Idiotype) Alexa Fluor 750 MAb (Clone 9
Size
100 µg
Qty
Maker
R&D SYSTEMS
Cat.No.
MAB9616-SP
Product
Anti-Adalimumab (Anti-Idiotype) MAb (Clone 2235F) (25 ug)
Size
25 ug
Qty
Data Sheet
Maker
R&D SYSTEMS
Cat.No.
MAB9546-100
Product
Anti-Adalimumab (Anti-Idiotype) MAb (Clone 972557) (100 ug)
Size
100 ug
Qty
Data Sheet
Maker
R&D SYSTEMS
Cat.No.
MAB9546-SP
Product
Anti-Adalimumab (Anti-Idiotype) MAb (Clone 972557) (25 ug)
Size
25 ug
Qty
Data Sheet
Maker
R&DSYSTEM
Cat.No.
FAB10180U-100UG
Product
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 350 MAb (Clone 2
Size
100 µg
Qty
Maker
R&DSYSTEM
Cat.No.
FAB9545U-100UG
Product
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 350 MAb (Clone 9
Size
100 µg
Qty
Maker
R&DSYSTEM
Cat.No.
FAB10180V-100UG
Product
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 405 MAb (Clone 2
Size
100 µg
Qty
Maker
R&DSYSTEM
Cat.No.
FAB9545V-100UG
Product
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 405 MAb (Clone 9
Size
100 µg
Qty
Maker
R&DSYSTEM
Cat.No.
FAB10180G-100UG
Product
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 488 MAb (Clone 2
Size
100 µg
Qty
Maker
R&DSYSTEM
Cat.No.
FAB9545G-100UG
Product
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 488 MAb (Clone 9
Size
100 µg
Qty
Maker
R&DSYSTEM
Cat.No.
FAB10180X-100UG
Product
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 532 MAb (Clone 2
Size
100 µg
Qty
Maker
R&DSYSTEM
Cat.No.
FAB9545X-100UG
Product
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 532 MAb (Clone 9
Size
100 µg
Qty
Maker
R&DSYSTEM
Cat.No.
FAB10180T-100UG
Product
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 594 MAb (Clone 2
Size
100 µg
Qty
Maker
R&DSYSTEM
Cat.No.
FAB9545T-100UG
Product
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 594 MAb (Clone 9
Size
100 µg
Qty
Maker
R&DSYSTEM
Cat.No.
FAB10180R-100UG
Product
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 647 MAb (Clone 2
Size
100 µg
Qty
Maker
R&DSYSTEM
Cat.No.
FAB9545R-100UG
Product
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 647 MAb (Clone 9
Size
100 µg
Qty
Maker
R&DSYSTEM
Cat.No.
FAB10180N-100UG
Product
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 700 MAb (Clone 2
Size
100 µg
Qty
Maker
R&DSYSTEM
Cat.No.
FAB9545N-100UG
Product
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 700 MAb (Clone 9
Size
100 µg
Qty
Maker
R&DSYSTEM
Cat.No.
FAB10180S-100UG
Product
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 750 MAb (Clone 2
Size
100 µg
Qty
Maker
R&DSYSTEM
Cat.No.
FAB9545S-100UG
Product
Anti-Aducanumab (Anti-Idiotype) Alexa Fluor 750 MAb (Clone 9
Size
100 µg
Qty
Maker
R&D SYSTEMS
Cat.No.
MAB10180-SP
Product
Anti-Aducanumab (Anti-Idiotype) MAb (Clone 2374E) (25 ug)
Size
25 ug
Qty
Data Sheet
Maker
R&D SYSTEMS
Cat.No.
MAB9545-100
Product
Anti-Aducanumab (Anti-Idiotype) MAb (Clone 975942) (100 ug)
Size
100 ug
Qty
Data Sheet
Maker
R&D SYSTEMS
Cat.No.
MAB9545-SP
Product
Anti-Aducanumab (Anti-Idiotype) MAb (Clone 975942) (25 ug)
Size
25 ug
Qty
Data Sheet
Maker
R&D SYSTEMS
Cat.No.
MAB10246-100
Product
Anti-Alemtuzumab (Anti-Idiotype) MAb (Clone 2499A) (100 ug)
Size
100 ug
Qty
Data Sheet
Maker
R&D SYSTEMS
Cat.No.
MAB10246-SP
Product
Anti-Alemtuzumab (Anti-Idiotype) MAb (Clone 2499A) (25 ug)
Size
25 ug
Qty
Data Sheet
Maker
R&D SYSTEMS
Cat.No.
FAB9584U-100UG
Product
Anti-Brentuximab (Anti-Idiotype) Alexa Fluor 350 MAb (2262C) (100 ug)
Size
100 ug
Qty
Data Sheet
Maker
R&D SYSTEMS
Cat.No.
FAB9584V-100UG
Product
Anti-Brentuximab (Anti-Idiotype) Alexa Fluor 405 MAb (2262C) (100 ug)
Size
100 ug
Qty
Data Sheet
Maker
R&D SYSTEMS
Cat.No.
FAB9584T-100UG
Product
Anti-Brentuximab (Anti-Idiotype) Alexa Fluor 594 MAb (2262C) (100 ug)
Size
100 ug
Qty
Data Sheet
Maker
R&D SYSTEMS
Cat.No.
FAB9584R-100UG
Product
Anti-Brentuximab (Anti-Idiotype) Alexa Fluor 647 MAb (2262C) (100 ug)
Size
100 ug
Qty
Data Sheet
Maker
R&D SYSTEMS
Cat.No.
FAB9584N-100UG
Product
Anti-Brentuximab (Anti-Idiotype) Alexa Fluor 700 MAb (2262C) (100 ug)
Size
100 ug
Qty
Data Sheet
Maker
R&D SYSTEMS
Cat.No.
FAB9584S-100UG
Product
Anti-Brentuximab (Anti-Idiotype) Alexa Fluor 750 MAb (2262C) (100 ug)
Size
100 ug
Qty
Data Sheet
Maker
R&D SYSTEMS
Cat.No.
MAB9584-SP
Product
Anti-Brentuximab (Anti-Idiotype) MAb (Clone 2262C) (25 ug)
Size
25 ug
Qty
Data Sheet
Maker
R&D SYSTEMS
Cat.No.
FAB9626U-100UG
Product
Anti-Cetuximab (Anti-Idiotype) Alexa Fluor 350 MAb (2259C) (100 ug)
Size
100 ug
Qty
Data Sheet
Maker
R&D SYSTEMS
Cat.No.
FAB9626V-100UG
Product
Anti-Cetuximab (Anti-Idiotype) Alexa Fluor 405 MAb (2259C) (100 ug)
Size
100 ug
Qty
Data Sheet
Maker
R&D SYSTEMS
Cat.No.
FAB9626G-100UG
Product
Anti-Cetuximab (Anti-Idiotype) Alexa Fluor 488 MAb (2259C) (100 ug)
Size
100 ug
Qty
Data Sheet
전체보기

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주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS
이디오타입 항체 제작서비스 (Anti-Idiotype Antibody) . . .

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