| Dynamin |
|
|
| Cat. No. |
Product |
Activity |
| 1774 |
Dynamin inhibitory peptide |
Dynamin
inhibitor |
| 1775 |
Dynamin inhibitory peptide,
myristoylated |
Cell-permeable dynamin inhibitor |
| 2897 |
Dynasore |
Non-competitive dynamin inhibitor |
| 4222 |
Dynole 34-2 |
Dynamin I inhibitor |
| 5364 |
Hydroxy Dynasore |
Dynamin inhibitor; analog of dynasore (Cat. No. 2897) |
| 6799 |
MB 0223 |
Dynamin-related GTPase DRP1 partial inhibitor |
| 3982 |
Mdivi 1 |
Selective dynamin inhibitor; attenuates mitochondrial division
and apoptosis |
| 6897 |
P110 |
Dynamin-related protein 1 (Drp1) inhibitor; cell-permeable |
|
|
|
| Heterotrimeric
G-protein GTPases |
|
| Cat. No. |
Product |
Activity |
| 4567 |
CCG 50014 |
Potent and
selective inhibitor of regulator of G-protein signaling 4 (RGS4) protein |
| 5642 |
CMPD101 |
Potent and selective GRK2/3 inhibitor |
| 5245 |
Ebselen |
Selectively inhibits Gq protein signaling |
| 3090 |
Gallein |
Inhibitor of Gβ/γ signaling |
| 3594 |
GRK2i |
GRK2 inhibitory polypeptide; Gβ/γ antagonist |
| 1192 |
Mastoparan |
Activates Gi and
Go |
| 1240 |
NF 023 |
Inhibitor of Go/i α-subunits; also P2X1 purinoceptor antagonist |
| 1400 |
SCH 202676 hydrobromide |
Inhibitor of ligand binding to G-protein-coupled receptors |
| 7352 |
YM 254890 |
Gα-protein inhibitor; potent inhibitor of Gq/11 signaling |
|
|
|
| Protein-synthesizing
GTPases |
|
| Cat. No. |
Product |
Activity |
| 3657 |
Sal 003 |
Inhibitor of
eIF2α dephosphorylation; cell permeable |
| 2347 |
Salubrinal |
Selective inhibitor of eIF2α dephosphorylation |
|
|
|
| Small
Monomeric GTPases - Arf GTPases |
|
| Cat. No. |
Product |
Activity |
| 3584 |
Golgicide A |
Potent,
selective and reversible inhibitor of GBF1 ArfGEF |
| 5986 |
NAV 2729 |
Selective ARF6 inhibitor |
| 3324 |
QS 11 |
ARFGAP1 inhibitor; modulates Wnt/β-catenin signaling |
| 2849 |
SecinH3 |
Sec7-specific GEF inhibitor; selective for cytohesin family |
|
|
|
| Small
Monomeric GTPases - EPAC |
|
| Cat. No. |
Product |
Activity |
| 5969 |
(R)-CE3F4 |
Epac inhibitor; R-enantiomer
of CE3F4 (Cat. No. 4793) |
| 1645 |
8-CPT-2Me-cAMP, sodium salt |
Selective Epac activator |
| 4853 |
8-pCPT-2-O-Me-cAMP-AM |
Selective Epac activator;
cell-permeable analog of 8CPT-2Me-cAMP (Cat.
No. 1645) |
| 4793 |
CE3F4 |
Noncompetitive Epac1 inhibitor |
| 6320 |
ESI 05 |
Epac2 inhibitor |
| 4773 |
ESI 09 |
Epac inhibitor |
| 4844 |
HJC 0350 |
Selective Epac2 inhibitor |
|
|
|
| Small
Monomeric GTPases - Ras GTPases |
|
| Cat. No. |
Product |
Activity |
| 7713 |
AMG 510 |
Potent and
selective KRASG12C inhibitor |
| 6857 |
BAY 293 |
Potent KRas/SOS1 interaction inhibitor |
| 6791 |
BC-LI-0186 |
Leucyl-tRNA synthase/Ras-related GTP-binding protein D
interaction inhibitor |
| 6407 |
Fendiline Hydrochloride |
Inhibits KRas localization to the plasma membrane; also L-type
calcium channel blocker |
| 5607 |
GNF 7 |
Ras signaling inhibitor; inhibits Ack1 and GCK |
| 6429 |
ML 210 |
Selectively kills mutant HRAS-expressing cells; glutathione
peroxidase inhibitor |
| 7488 |
MRTX 849 |
Mutation-selective inhibitor of KRASG12C |
| 5411 |
RBC8 |
RalA and RalB inhibitor |
| 6920 |
SAH-SOS1A |
KRas/SOS1 interaction inhibitor |
| 6111 |
Zoledronic Acid |
Ras signaling inhibitor; also potent farnesyl diphosphate (FPP)
synthase inhibitor |
|
|
|
| Small
Monomeric GTPases - Rho GTPases |
|
| Cat. No. |
Product |
Activity |
| 6701 |
1A-116 |
Rac1
inhibitor; blocks Rac1-P-Rex1 interaction |
| 5050 |
CASIN |
Cdc42 inhibitor |
| 5233 |
CCG 1423 |
Rho/SRF pathway inhibitor; induces intermediate mesoderm
differentiation from ESCs |
| 4568 |
CPYPP |
DOCK2-Rac1 interaction inhibitor |
| 7089 |
CSN5i-3 |
Increases expression and activity of Rho GTPases; also CSN5
inhibitor |
| 6248 |
EHop 016 |
Rac inhibitor |
| 3872 |
EHT 1864 |
Potent Rac family inhibitor |
| 4266 |
ML 141 |
Selective Cdc42 Rho family inhibitor |
| 2161 |
NSC 23766 |
Selective inhibitor of Rac1-GEF interaction; antioncogenic |
| 5003 |
Rhosin hydrochloride |
Rho inhibitor |