고마바이오텍(주)

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제품 상세
GTPases Inhibitors 이미지

GTPases Inhibitors

GTPases 효소에 작용하는 inhibitor, activator를 소개합니다. (Dynamin, small G-protein GTPase, Rho/Ras GTPase inhibitors)

프린트 제품 문의

특징

  

  • GTPase는 GTP에서 g-phosphate 결합을 가수분해하여 GDP를 형성하는 효소입니다.
  • GTPase는 신호전달, 단백질합성, translocation, 세포 성장 조절과 분화, vesicular transport 조절에 관여합니다.
  • Dynamin은 multi-domain을 갖는 고분자량의 GTPase로 receptor-mediated endocytosis, synaptic vesicle recycling, 암세포의 운반, spermatogenesis에 관여합니다. DNM2의 mutation은 neuromuscular diseae와 관련이 있습니다.
  • Small monomeric GTPases은 small G-proteins으로도 불리며 Ga 단백질과 상동적입니다. 세포내 신호전달 경로에 관여하는 효소군 입니다. 

 

 

주요 제품 

 

Dynamin
Cat. No. Product Activity
1774 Dynamin inhibitory peptide Dynamin inhibitor
1775 Dynamin inhibitory peptide, myristoylated Cell-permeable dynamin inhibitor
2897 Dynasore Non-competitive dynamin inhibitor
4222 Dynole 34-2 Dynamin I inhibitor
5364 Hydroxy Dynasore Dynamin inhibitor; analog of dynasore (Cat. No. 2897)
6799 MB 0223 Dynamin-related GTPase DRP1 partial inhibitor
3982 Mdivi 1 Selective dynamin inhibitor; attenuates mitochondrial division and apoptosis
6897 P110 Dynamin-related protein 1 (Drp1) inhibitor; cell-permeable
Heterotrimeric G-protein GTPases
Cat. No. Product Activity
4567 CCG 50014 Potent and selective inhibitor of regulator of G-protein signaling 4 (RGS4) protein
5642 CMPD101 Potent and selective GRK2/3 inhibitor
5245 Ebselen Selectively inhibits Gq protein signaling
3090 Gallein Inhibitor of Gβ/γ signaling
3594 GRK2i GRK2 inhibitory polypeptide; Gβ/γ antagonist
1192 Mastoparan Activates Gi and Go
1240 NF 023 Inhibitor of Go/i α-subunits; also P2X1 purinoceptor antagonist
1400 SCH 202676 hydrobromide Inhibitor of ligand binding to G-protein-coupled receptors
7352 YM 254890 Gα-protein inhibitor; potent inhibitor of Gq/11 signaling
Protein-synthesizing GTPases
Cat. No. Product Activity
3657 Sal 003 Inhibitor of eIF2α dephosphorylation; cell permeable
2347 Salubrinal Selective inhibitor of eIF2α dephosphorylation
Small Monomeric GTPases - Arf GTPases
Cat. No. Product Activity
3584 Golgicide A Potent, selective and reversible inhibitor of GBF1 ArfGEF
5986 NAV 2729 Selective ARF6 inhibitor
3324 QS 11 ARFGAP1 inhibitor; modulates Wnt/β-catenin signaling
2849 SecinH3 Sec7-specific GEF inhibitor; selective for cytohesin family
Small Monomeric GTPases - EPAC
Cat. No. Product Activity
5969 (R)-CE3F4 Epac inhibitor; R-enantiomer of CE3F4 (Cat. No. 4793)
1645 8-CPT-2Me-cAMP, sodium salt Selective Epac activator
4853 8-pCPT-2-O-Me-cAMP-AM Selective Epac activator; cell-permeable analog of 8CPT-2Me-cAMP (Cat. No. 1645)
4793 CE3F4 Noncompetitive Epac1 inhibitor
6320 ESI 05 Epac2 inhibitor
4773 ESI 09 Epac inhibitor
4844 HJC 0350 Selective Epac2 inhibitor
Small Monomeric GTPases - Ras GTPases
Cat. No. Product Activity
7713 AMG 510  Potent and selective KRASG12C inhibitor
6857 BAY 293 Potent KRas/SOS1 interaction inhibitor
6791 BC-LI-0186 Leucyl-tRNA synthase/Ras-related GTP-binding protein D interaction inhibitor
6407 Fendiline Hydrochloride Inhibits KRas localization to the plasma membrane; also L-type calcium channel blocker
5607 GNF 7 Ras signaling inhibitor; inhibits Ack1 and GCK
6429 ML 210 Selectively kills mutant HRAS-expressing cells; glutathione peroxidase inhibitor
7488 MRTX 849 Mutation-selective inhibitor of KRASG12C
5411 RBC8 RalA and RalB inhibitor
6920 SAH-SOS1A KRas/SOS1 interaction inhibitor
6111 Zoledronic Acid Ras signaling inhibitor; also potent farnesyl diphosphate (FPP) synthase inhibitor
Small Monomeric GTPases - Rho GTPases
Cat. No. Product Activity
6701 1A-116 Rac1 inhibitor; blocks Rac1-P-Rex1 interaction
5050 CASIN Cdc42 inhibitor
5233 CCG 1423 Rho/SRF pathway inhibitor; induces intermediate mesoderm differentiation from ESCs
4568 CPYPP DOCK2-Rac1 interaction inhibitor
7089 CSN5i-3 Increases expression and activity of Rho GTPases; also CSN5 inhibitor
6248 EHop 016 Rac inhibitor
3872 EHT 1864 Potent Rac family inhibitor
4266 ML 141 Selective Cdc42 Rho family inhibitor
2161 NSC 23766 Selective inhibitor of Rac1-GEF interaction; antioncogenic
5003 Rhosin hydrochloride Rho inhibitor

 

주문정보

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS
(R)-CE3F4 (10 MG) 5969 10 mg TOCRIS
1A-116 (10 MG) 6701 10 mg TOCRIS
1A-116 (50 MG) 6701 50 mg TOCRIS
8-CPT-2Me-cAMP, sodium salt (1 mg) 1645 1 mg TOCRIS
8-pCPT-2-O-Me-cAMP-AM (100 ug) 4853 100 ug TOCRIS
AMG 510 7713 10 mg TOCRIS
AMG 510 7713 50 mg TOCRIS
BAY 293 (5 MG) 6857 5 mg TOCRIS
BC-LI-0186 (25 MG) 6791 25 mg TOCRIS
BC-LI-0186 (5 MG) 6791 5 mg TOCRIS
CASIN (10 mg) 5050 10 mg TOCRIS
CE3F4 (10 mg) 4793 10 mg TOCRIS
CE3F4 (50 mg) 4793 50 mg TOCRIS
CMPD101 (10 mg) 5642 10 mg TOCRIS
CPYPP (10 mg) 4568 10 mg TOCRIS
CPYPP (50 mg) 4568 50 mg TOCRIS
CSN5i-3 7089 2 mg TOCRIS
Dynasore (10 mg) 2897 10 mg TOCRIS
Dynasore (50 mg) 2897 50 mg TOCRIS
Dynole 34-2 (10 mg) 4222 10 mg TOCRIS
Dynole 34-2 (50 mg) 4222 50 mg TOCRIS
Ebselen (10 mg) 5245 10 mg TOCRIS
Ebselen (50 mg) 5245 50 mg TOCRIS
EHop 016 (25 MG) 6248 25 mg TOCRIS
EHop 016 (5 MG) 6248 5 mg TOCRIS
EHT 1864 (10 mg) 3872 10 mg TOCRIS
EHT 1864 (50 mg) 3872 50 mg TOCRIS
ESI 05 (25 MG) 6320 25 mg TOCRIS
ESI 05 (5 MG) 6320 5 mg TOCRIS
ESI 09 (10 mg) 4773 10 mg TOCRIS
ESI 09 (50 mg) 4773 50 mg TOCRIS
Fendiline Hydrochloride (10 MG) 6407 10 mg TOCRIS
Fendiline Hydrochloride (50 MG) 6407 50 mg TOCRIS
Gallein (50 mg) 3090 50 mg TOCRIS
GNF 7 (10 mg) 5607 10 mg TOCRIS
GNF 7 (50 mg) 5607 50 mg TOCRIS
Golgicide A (10 mg) 3584 10 mg TOCRIS
Golgicide A (50 mg) 3584 50 mg TOCRIS
GRK2i (1 mg) 3594 1 mg TOCRIS
HJC 0350 (10 mg) 4844 10 mg TOCRIS
HJC 0350 (50 mg) 4844 50 mg TOCRIS
Hydroxy Dynasore (10 mg) 5364 10 mg TOCRIS
Hydroxy Dynasore (50 mg) 5364 50 mg TOCRIS
KRpep-2d 7928 1 mg TOCRIS
Mdivi 1 (10 mg) 3982 10 mg TOCRIS
Mdivi 1 (50 mg) 3982 50 mg TOCRIS
ML 141 (10 mg) 4266 10 mg TOCRIS
ML 141 (50 mg) 4266 50 mg TOCRIS
ML 210 (10 MG) 6429 10 mg TOCRIS
MRTX 849 7488 50 mg TOCRIS
전체보기
Maker
TOCRIS
Cat.No.
5969
Product
(R)-CE3F4 (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6701
Product
1A-116 (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6701
Product
1A-116 (50 MG)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
1645
Product
8-CPT-2Me-cAMP, sodium salt (1 mg)
Size
1 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4853
Product
8-pCPT-2-O-Me-cAMP-AM (100 ug)
Size
100 ug
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7713
Product
AMG 510
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7713
Product
AMG 510
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6857
Product
BAY 293 (5 MG)
Size
5 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6791
Product
BC-LI-0186 (25 MG)
Size
25 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6791
Product
BC-LI-0186 (5 MG)
Size
5 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5050
Product
CASIN (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4793
Product
CE3F4 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4793
Product
CE3F4 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5642
Product
CMPD101 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4568
Product
CPYPP (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4568
Product
CPYPP (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7089
Product
CSN5i-3
Size
2 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
2897
Product
Dynasore (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
2897
Product
Dynasore (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4222
Product
Dynole 34-2 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4222
Product
Dynole 34-2 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5245
Product
Ebselen (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5245
Product
Ebselen (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6248
Product
EHop 016 (25 MG)
Size
25 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6248
Product
EHop 016 (5 MG)
Size
5 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3872
Product
EHT 1864 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3872
Product
EHT 1864 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6320
Product
ESI 05 (25 MG)
Size
25 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6320
Product
ESI 05 (5 MG)
Size
5 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4773
Product
ESI 09 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4773
Product
ESI 09 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6407
Product
Fendiline Hydrochloride (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6407
Product
Fendiline Hydrochloride (50 MG)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3090
Product
Gallein (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5607
Product
GNF 7 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5607
Product
GNF 7 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3584
Product
Golgicide A (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3584
Product
Golgicide A (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3594
Product
GRK2i (1 mg)
Size
1 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4844
Product
HJC 0350 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4844
Product
HJC 0350 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5364
Product
Hydroxy Dynasore (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5364
Product
Hydroxy Dynasore (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7928
Product
KRpep-2d
Size
1 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3982
Product
Mdivi 1 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3982
Product
Mdivi 1 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4266
Product
ML 141 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4266
Product
ML 141 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6429
Product
ML 210 (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7488
Product
MRTX 849
Size
50 mg
Qty
Data Sheet
MSDS
전체보기

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주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS

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 0.5 ml Elite Pre-stained Protein Ladder (2 x 0.25 ml) PAL-EPL-500 0.5ml 500
Maker
Cat.No.
Product
Size
Qty
Data Sheet
MSDS

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