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제품 상세
Flow Cytometry 분석을 위한 CD Marker Antibody 이미지

Flow Cytometry 분석을 위한 CD Marker Antibody

FACS 실험에 이용되는 Cell Surface 항체인 CD Marker Antibody를 소개합니다. 줄기세포, 과립구, 림프구, NK세포 등 세포타입에 특정되고 다양한 형광이 labeling된 CD 마커 항체를 확인하세요.

CD marker란?

 

  • FACS(Fluorescence-activated cell sorting)는 이종 세포로 구성된 혼합물에서  각 세포의 특정 빛 분사 및 형광 특성을 이용하여 한번에 하나의 세포를 분류해주는 기법입니다. 
  • 세포 표면 항원 무리(Cluster of differentiation,  cluster of designation, 또는 classification determinant)는 약자로 CD라고 합니다. CD marker는 기존에는 cell surface에 존재하는 것으로 알려져 있었으며, 그로 인해 Cell surface marker라고 명명되었지만, 그 외의 영역에 발현되는 CD marker도 존재하는 것으로 밝혀졌습니다. 
  • 세포 유형에 따라 이 CD 인자가 다르게 발현되어 있습니다. 따라서, 이 CD 인자에 대한 항체를 사용하면 세포 유형을 파악하는 데 도움이 됩니다. 면역세포인 leukocyte, T cell, B cell 등에 각각 특이적인 CD marker들도 알려져 있으며, stem cell에 특이적인 marker도 알려져 있습니다. 이를 이용하여 면역학 또는 줄기세포 연구에 활발히 이용됩니다.
  • 예를 들면, 줄기세포에는 CD34가 발현되어 있습니다. 줄기세포에서 분화된 T-Lymphocyte, B-Lymphocyte, Monocyte, Thromobocyte, Granulocyte은 모두 CD45를 발현합니다. 이 중 T-lymphocyte는 CD3도 발현하며, Helper T-lymphocyte은 CD4를, Cytotoxic T-lymphocyte은 CD8을 발현합니다.  이처럼 각 세포는 다른 CD marker를 발현하기 때문에 이를 인식하는 항체를 이용하면 어떤 세포인지 확인할 수 있습니다.

 

 

세포 유형에 따른 CD marker     

 

Cell Type Common Human CD markers
T Cell CD3, CD4, CD8
B Cell CD19, CD20
Dendritic Cell CD11c, CD123
Natural Killer (NK) Cell CD56
Stem Cell/Precusor CD34 (hematopoietic stem cell only)
Monocyte/Macrophage CD14, CD33
Granulocyte CD66b
Platelet CD41, CD61, CD62
Erythrocyte CD235a

* 출처 : 위키피디아

 

 

CD marker별 주요 제품  

 

Target Un-conjugated APC APC-
Cyanine 5.5
APC-
Cyanine 7
Biotin FITC PE PE-
Cyanine 5
PE-
Cyanine 5.5
PE-
Cyanine 7
PE-
Texas Red
PerCP Cyanine 5
Anti-CD1 ARG21107       ARG21109 ARG21108 ARG21110            
Anti-CD1a ARG62761 ARG53785       ARG62762 ARG53786            
Anti-CD1b ARG65539         ARG65538 ARG42342            
Anti-CD1c ARG65474 ARG42328         ARG54264            
Anti-CD1d ARG23174       ARG23172 ARG23173              
Anti-CD1w2 ARG22736           ARG22737            
Anti-CD1b+CD1c ARG23327         ARG23326              
Anti-CD2 ARG20811 ARG53787     ARG20813 ARG20812 ARG20814            
Anti-CD2AP ARG59346                        
Anti-CD3 ARG21150 ARG22344   ARG22157 ARG21152 ARG21151 ARG21153 ARG22153 ARG22155 ARG22156   ARG53822 ARG22154
Anti-CD3 zeta ARG55533                        
Anti-CD3e ARG21116 ARG20820     ARG21118 ARG21117 ARG21119 ARG20821         ARG20822
Anti-CD4 ARG21146 ARG22339 ARG21985 ARG21986 ARG21148 ARG21147 ARG21149 ARG21124 ARG21983 ARG21984 ARG21299 ARG53842 ARG21982
Anti-CD4a ARG22650                        
Anti-CD5 ARG21987 ARG21991     ARG21989 ARG21988 ARG21990 ARG20828       ARG42280  
Anti-CD6 ARG62903         ARG65850 ARG53883            
Anti-CD7 ARG62918 ARG53893       ARG62919 ARG53894         ARG54275  
Anti-CD8 ARG62928 ARG53900 ARG21320 ARG21321 ARG62927 ARG62930 ARG53901 ARG21316 ARG21318 ARG21319 ARG21314 ARG53902 ARG21317
Anti-CD8a+CD8b ARG22644                        
Anti-CD8a ARG21238 ARG53910 ARG21998 ARG21999 ARG21240 ARG21239 ARG21241 ARG21129 ARG62941 ARG21997     ARG21242
Anti-CD8b ARG65386       ARG21194 ARG65387 ARG65388            
Anti-CD9 ARG62945 ARG53914     ARG65441 ARG62946 ARG62947            
Anti-CD10 ARG62696 ARG54281     ARG62695 ARG62697 ARG53751         ARG54282  
Anti-CD11a ARG21250 ARG21254     ARG21252 ARG21251 ARG21253 ARG21255   ARG20834      
Anti-CD11b ARG20835 ARG20839   ARG20844 ARG20837 ARG20836 ARG20838 ARG20840   ARG20843     ARG20842
Anti-CD11c ARG21322       ARG21324 ARG21323 ARG21325         ARG53763  
Anti-CD11d ARG22728                        
Anti-CD11R1 ARG22640                        
Anti-CD13 ARG21326 ARG53764     ARG65558 ARG21327 ARG21328         ARG54312  
Anti-CD14 ARG21334 ARG21338 ARG21343 ARG21344 ARG21336 ARG21335 ARG21337 ARG21339 ARG21341 ARG21342   ARG53769  
Anti-CD15 ARG62735 ARG54270     ARG62734 ARG62736 ARG54271         ARG54272  
Anti-CD16 ARG40693 ARG42247     ARG23013 ARG21346 ARG23014 ARG21349       ARG42248  
Anti-CD16.2 ARG23181         ARG23182              
Anti-CD16/32 ARG20908 ARG20912     ARG20910 ARG20909 ARG20911 ARG20913 ARG20915 ARG20916      
Anti-CD16a ARG52704                        
Anti-CD17 ARG56105                        
Anti-CD18 ARG20845 ARG53779     ARG20847 ARG20846 ARG20848            
Anti-CD19 ARG55048 ARG55043 ARG20865 ARG20866 ARG55044 ARG55045 ARG55046 ARG20863 ARG20856 ARG20857 ARG21261 ARG55047 ARG20855
Anti-CD20 ARG65383 ARG54197   ARG21280 ARG65384 ARG65385 ARG54198 ARG21278   ARG21279   ARG54199  
Anti-CD21 ARG21134       ARG21136 ARG21135 ARG21137         ARG42361  
Anti-CD22 ARG20867 ARG20871     ARG20869 ARG20868 ARG20870 ARG20872          
Anti-CD23 ARG20873 ARG20877     ARG20875 ARG20874 ARG20876     ARG20878      
Anti-CD24 ARG22086 ARG22090     ARG22088 ARG22087 ARG22089 ARG22091          
Anti-CD25 ARG20887 ARG20891     ARG20889 ARG20888 ARG20890 ARG20892   ARG20894   ARG54274  
Anti-CD26 ARG62788 ARG53802       ARG62789 ARG53803            
Anti-CD27 ARG62793 ARG53812       ARG62794 ARG53813            
Anti-CD28 ARG22007 ARG21184     ARG22009 ARG22008 ARG65473 ARG22012       ARG53815  
Anti-CD30 ARG22013 ARG53824     ARG22015 ARG22014 ARG22016            
Anti-CD31 ARG20901 ARG20905     ARG20903 ARG20902 ARG20904     ARG20907   ARG54268  
Anti-CD32 ARG65391       ARG22889 ARG22891 ARG22892            
Anti-CD32B ARG23571         ARG23572              
Anti-CD33 ARG62818 ARG54313     ARG62817 ARG65561 ARG54314 ARG22171 ARG22172     ARG54315  
Anti-CD35 ARG65437 ARG42310       ARG65438 ARG54242            
Anti-CD36 ARG23025 ARG53834       ARG23027 ARG23028            
Anti-CD37 ARG55074                        
Anti-CD38 ARG62829 ARG53837     ARG62828 ARG62830 ARG53838 ARG20922       ARG53839  
Anti-CD39 ARG22507 ARG42315       ARG22506 ARG22508            
Anti-CD40 ARG20924 ARG20928     ARG20926 ARG20925 ARG20927 ARG20929          
Anti-CD41 ARG62841 ARG53846     ARG62840 ARG62842 ARG53847         ARG42249  
Anti-CD41+CD61 ARG22713         ARG22742 ARG22743            
Anti-CD42a ARG23072 ARG42297       ARG23071 ARG22912            
Anti-CD42b ARG21352 ARG21356     ARG21354 ARG21353 ARG21355 ARG21357          
Anti-CD43 ARG21358 ARG21362     ARG21360 ARG21359 ARG21361 ARG21363          
Anti-CD45 ARG21016 ARG21020 ARG21025 ARG21015 ARG21018 ARG21017 ARG21019 ARG21021 ARG21023 ARG21024 ARG21371 ARG53858 ARG21022
Anti-CD45.1 ARG21005                        
Anti-CD45R ARG65535 ARG65536 ARG22031 ARG22032 ARG22026 ARG65532 ARG65534 ARG22027 ARG22029 ARG22030     ARG22028
Anti-CD45R0 ARG65549 ARG53859       ARG62861 ARG53860            
Anti-CD45RA ARG21377 ARG54277     ARG62862 ARG21378 ARG21379 ARG21380       ARG54279  
Anti-CD45RB ARG22033 ARG53861     ARG22035 ARG22034 ARG22036 ARG22037          
Anti-CD45RC ARG22038       ARG22039 ARG22041 ARG22040            
Anti-CD45RO ARG22752                        
Anti-CD46 ARG62869 ARG53863     ARG62868 ARG62870 ARG53864            
Anti-CD47 ARG62871         ARG62872              
Anti-CD48 ARG62874 ARG53865     ARG62873 ARG62875 ARG53866            
Anti-CD49a ARG22420         ARG22496 ARG22497            
Anti-CD49b ARG23695 ARG21030   ARG21031 ARG23696 ARG23698 ARG23699            
Anti-CD49c ARG23140         ARG23139 ARG23141            
Anti-CD49d ARG23116       ARG21043 ARG23115 ARG21289            
Anti-CD49e ARG22042         ARG22043 ARG22045            
Anti-CD49f ARG23224         ARG23223 ARG23225            
Anti-CD50 ARG62880       ARG62879   ARG53869            
Anti-CD51 ARG21381         ARG21382 ARG21383            
Anti-CD51+CD61 ARG23099                        
Anti-CD52 ARG62881 ARG53870       ARG62882 ARG53871            
Anti-CD53 ARG62883         ARG62884 ARG53872            
Anti-CD54 ARG21290 ARG21294     ARG21292 ARG21291 ARG21293         ARG53876  
Anti-CD55 ARG21384       ARG62890 ARG21385 ARG21386 ARG21387          
Anti-CD56 ARG62894 ARG53877     ARG62893 ARG62895 ARG53878         ARG53879  
Anti-CD57 ARG21389 ARG42321     ARG21391 ARG21390 ARG21392 ARG21393          
Anti-CD58 ARG23112 ARG54280     ARG62896 ARG62897 ARG53880            
Anti-CD61 ARG20931 ARG54306       ARG20932 ARG20933         ARG54308  
Anti-CD62E ARG20934 ARG20960     ARG20958 ARG20935 ARG20959 ARG20961          
Anti-CD62L ARG22894 ARG53884   ARG22052 ARG22047 ARG22893 ARG22048 ARG22050   ARG22051      
Anti-CD62P ARG23102 ARG54215     ARG65408 ARG65409 ARG54216            
Anti-CD63 ARG22407 ARG53886     ARG62911 ARG62913 ARG53887         ARG53888  
Anti-CD64 ARG65361 ARG54185     ARG65362 ARG65363 ARG54186            
Anti-CD65 ARG42410         ARG42411              
Anti-CD65s           ARG22761              
Anti-CD66a+CD66c+CD66d ARG22498                        
Anti-CD66b ARG66287 ARG66290       ARG66288 ARG66289            
Anti-CD66e ARG62915 ARG42351                      
Anti-CD68 ARG23387 ARG42327       ARG23386 ARG23388            
Anti-CD69 ARG62916 ARG53890       ARG62917 ARG22056 ARG22058   ARG22060   ARG53892  
Anti-CD70 ARG56102           ARG42337            
Anti-CD72 ARG20947       ARG20949 ARG20948 ARG20950            
Anti-CD74 ARG65688       ARG22176 ARG55521 ARG22177            
Anti-CD79a ARG62427 ARG54257       ARG65460 ARG54258            
Anti-CD79b ARG21400 ARG21404     ARG21402 ARG21401 ARG21403 ARG21405          
Anti-CD80 ARG20951 ARG20955     ARG20953 ARG20952 ARG20954 ARG20956       ARG53905  
Anti-CD81 ARG41313 ARG41848     ARG21038 ARG23245 ARG21039            
Anti-CD82 ARG23417 ARG65635     ARG65632 ARG65633 ARG65634            
Anti-CD83 ARG56144 ARG56147       ARG56145 ARG56146            
Anti-CD84 ARG65432 ARG54234       ARG65433 ARG54235            
Anti-CD85g ARG42412           ARG42413            
Anti-CD85j ARG23623         ARG23622              
Anti-CD86 ARG23462 ARG21092     ARG21090 ARG23461 ARG23463 ARG21093   ARG21095   ARG53909  
Anti-CD88 ARG22846       ARG22557 ARG22847 ARG54294            
Anti-CD89 ARG22518         ARG42293 ARG22521            
Anti-CD90 ARG20966 ARG20970     ARG20968 ARG20967 ARG20969 ARG20971          
Anti-CD90.2 ARG20972 ARG20976     ARG20974 ARG20973 ARG20975 ARG20977          
Anti-CD92 ARG23625         ARG23626 ARG23627            
Anti-CD94 ARG22077 ARG42268     ARG22079 ARG22078 ARG22080            
Anti-CD95 ARG21406 ARG21410     ARG21408 ARG21407 ARG21409            
Anti-CD97 ARG62953         ARG62954              
Anti-CD98 ARG62956       ARG62955 ARG62957 ARG53917            
Anti-CD99 ARG65389 ARG42266       ARG65390 ARG54200            
Anti-CD99R ARG62958         ARG62959 ARG53918            
Anti-CD101 ARG65412         ARG23531 ARG23532            
Anti-CD102 ARG21102       ARG21104 ARG21103 ARG21105            
Anti-CD103 ARG22081 ARG54226     ARG22083 ARG22082 ARG22084            
Anti-CD104 ARG23419         ARG23420              
Anti-CD105 ARG62699 ARG53753     ARG65492 ARG62701 ARG53754            
Anti-CD106 ARG20962       ARG20964 ARG20963 ARG20965            
Anti-CD107a ARG21096 ARG21098       ARG21097 ARG54251 ARG22182          
Anti-CD107b ARG22183 ARG54252     ARG22184 ARG65455 ARG54253 ARG22185          
Anti-CD108 ARG62704         ARG65488              
Anti-CD109 ARG42423           ARG42424            
Anti-CD116 ARG65394           ARG54204            
Anti-CD117 ARG65364 ARG54187 ARG21053 ARG21054 ARG65365 ARG65366 ARG54188 ARG21051         ARG21052
Anti-CD119 ARG40369                        
Anti-CD120a ARG66059       ARG66060   ARG42298            
Anti-CD123 ARG40386 ARG42267     ARG42269 ARG42270 ARG42275            
Anti-CD125 ARG40372                        
Anti-CD127 ARG58839                        
Anti-CD129 ARG42390           ARG42400            
Anti-CD130 ARG23136         ARG23321 ARG42420            
Anti-CD134 ARG23160 ARG42320       ARG23159 ARG42336            
Anti-CD135 ARG65425 ARG42300       ARG65426 ARG54230            
Anti-CD137 ARG43309 ARG42319         ARG42273            
Anti-CD137L ARG23616                        
Anti-CD138 ARG65410           ARG54219            
Anti-CD139 ARG65824         ARG65825              
Anti-CD140a ARG65373 ARG54189     ARG65374 ARG65375 ARG54190            
Anti-CD140b ARG65376 ARG54191         ARG54192            
Anti-CD146 ARG21220       ARG21222 ARG21221 ARG21223            
Anti-CD147 ARG62731 ARG53770     ARG62730 ARG62733 ARG53771            
Anti-CD148 ARG65504 ARG54283     ARG65505   ARG54284            
Anti-CD150 ARG23612 ARG42416       ARG42368 ARG23613            
Anti-CD151 ARG22965         ARG22966 ARG22967            
Anti-CD153 ARG42650                        
Anti-CD154 ARG41606         ARG41605 ARG41607            
Anti-CD157 ARG65543 ARG42318       ARG42333 ARG42272            
Anti-CD158d ARG62738 ARG54265         ARG53772            
Anti-CD158f ARG42255 ARG42305         ARG54305            
Anti-CD160 ARG65427 ARG42301         ARG54231            
Anti-CD161 ARG22930         ARG22929