Nuclear Hormone Receptor Services | NHR 스크리닝 서비스 | 고마바이오텍

특징

• 핵 수용체 활동에 대한 화학 물질, 약물 및 영양소의 영향을 조사하기 위해 다양한 세포 기반 핵 호르몬 수용체(NHR) 분석 메뉴를 제공합니다.
  
• Nuclear translocation, NHR co-activator interaction에 의한 수용체 활성화를 모니터링하는 20개 이상의 다양한 세포 분석을 제공합니다. 
• 16-24시간의 긴 compound incubation이 필요하지 않으므로 신속하며, 화학발광을 이용하여 민감하게 스크리닝 합니다. 
• Toxicology, Metabolic Diseases, Endocrinology등의 치료 관련성을 기반으로 맞춤형 수용체 그룹을 선택할 수 있습니다.
• 기능적으로 validated된 cell line을 이용하여 매 실험마다 고품질의 결과를 제공합니다.
• 타겟에 따라 Functional, Binding, Cell-based assay를 다양하게 제공합니다. 

 

Activation and inhibition of human estrogen receptor, ERβ

The indicated reference compounds were tested in dose response for their ability to either activate (left panel) or inhibit (right panel) human estrogen receptor, 

ERβ, as detected by measuring the amount of coactivator recruitment.

  

 

종류 

 

NHR Service List	Service Location	Item No.
AHR Human NHR Cell Based Agonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2450AG
AHR Human NHR Cell Based Antagonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2450AN
AHR Human NHR Cell Based PAM Protein-Protein Interaction Assay	DiscoverX	86-0003P-2450PM
AR Human Androgen NHR Binding (Agonist Radioligand) Assay	Cerep	933
AR Human Androgen NHR Binding (Agonist Radioligand) Assay	Panlabs	206000
AR Human Androgen NHR Cell Based Agonist & Antagonist Reporter Assay	Panlabs	302710
AR Human Androgen NHR Cell Based Agonist Nuclear Translocation Assay	DiscoverX	86-0013P-2445AG
AR Human Androgen NHR Cell Based Agonist Nuclear Translocation Assay	SAFETYscan - DiscoverX	87-1002-2445AG
AR Human Androgen NHR Cell Based Agonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2451AG
AR Human Androgen NHR Cell Based Agonist Reporter Assay	Panlabs	302710-0
AR Human Androgen NHR Cell Based Antagonist Nuclear Translocation Assay	DiscoverX	86-0013P-2445AN
AR Human Androgen NHR Cell Based Antagonist Nuclear Translocation Assay	SAFETYscan - DiscoverX	87-1002-2445AN
AR Human Androgen NHR Cell Based Antagonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2451AN
AR Human Androgen NHR Cell Based Antagonist Reporter Assay	Panlabs	302710-1
AR Human Androgen NHR Cell Based PAM Nuclear Translocation Assay	DiscoverX	86-0013P-2445PM
AR Human Androgen NHR Cell Based PAM Protein-Protein Interaction Assay	DiscoverX	86-0003P-2451PM
AR Human Androgen Receptor Translocation Functional Agonist & Antagonist Assay	Panlabs	302720
AR Human Androgen Receptor Translocation Functional Agonist Assay	Panlabs	302720-0
AR Human Androgen Receptor Translocation Functional Antagonist Assay	Panlabs	302720-1
CAR Human NHR Functional Agonist & Antagonist Coactivator Assay	Cerep	G187
CAR Human NHR Functional Agonist & Antagonist Coactivator Assay	Panlabs	307300
CAR Human NHR Functional Agonist Coactivator Assay	Cerep	3141
CAR Human NHR Functional Agonist Coactivator Assay	Panlabs	307300-0
CAR Human NHR Functional Antagonist Coactivator Assay	Cerep	3145
CAR Human NHR Functional Antagonist Coactivator Assay	Panlabs	307300-1
CAR Human NHR Functional Inverse Agonist Coactivator Assay	Cerep	3354
Endocrine Disruption Panel	Cerep	P402
ER (Non-Selective) Human Estrogen NHR Binding (Agonist Radioligand) Assay	Cerep	152
ERalpha Human Estrogen NHR Binding (Agonist Radioligand) Assay	Cerep	4087
ERalpha Human Estrogen NHR Binding (Agonist Radioligand) Assay	Panlabs	226010
ERalpha Human Estrogen NHR Cell Based Agonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2452AG
ERalpha Human Estrogen NHR Cell Based Antagonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2452AN
ERalpha Human Estrogen NHR Cell Based PAM Protein-Protein Interaction Assay	DiscoverX	86-0003P-2452PM
ERalpha Human Estrogen NHR Functional Agonist & Antagonist Coactivator Assay	Panlabs	311410
ERalpha Human Estrogen NHR Functional Agonist Coactivator Assay	Panlabs	311410-0
ERalpha Human Estrogen NHR Functional Antagonist Coactivator Assay	Panlabs	311410-1
ERbeta Human Estrogen NHR Binding (Agonist Radioligand) Assay	Panlabs	226050
ERbeta Human Estrogen NHR Functional Agonist & Antagonist Coactivator Assay	Panlabs	311440
ERbeta Human Estrogen NHR Functional Agonist Coactivator Assay	Panlabs	311440-0
ERbeta Human Estrogen NHR Functional Antagonist Coactivator Assay	Panlabs	311440-1
ERRalpha Human Estrogen-Related NHR Functional Agonist Coactivator Assay	Panlabs	311500-0
ERRbeta Human Estrogen-Related NHR Functional Agonist & Antagonist Coactivator Assay	Panlabs	311530
ERRbeta Human Estrogen-Related NHR Functional Agonist Coactivator Assay	Panlabs	311530-0
ERRbeta Human Estrogen-Related NHR Functional Antagonist Coactivator Assay	Panlabs	311530-1
ERRgamma Human Estrogen-Related NHR Functional Agonist Coactivator Assay	Panlabs	311560-0
ERRgamma Human Estrogen-Related NHR Functional Inverse Agonist Coactivator Assay	Cerep	3498
FXR Human Liver X Receptor-Like NHR Cell Based Agonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2453AG
FXR Human Liver X Receptor-Like NHR Cell Based Antagonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2453AN
FXR Human Liver X Receptor-Like NHR Cell Based PAM Protein-Protein Interaction Assay	DiscoverX	86-0003P-2453PM
FXR Human Liver X Receptor-Like NHR Functional Agonist & Antagonist Coactivator Assay	Panlabs	311600
FXR Human Liver X Receptor-Like NHR Functional Agonist Coactivator Assay	Panlabs	311600-0
FXR Human Liver X Receptor-Like NHR Functional Antagonist Coactivator Assay	Panlabs	311600-1
GR Human Glucocorticoid NHR Binding (Agonist Radioligand) Assay	Cerep	469
GR Human Glucocorticoid NHR Binding (Agonist Radioligand) Assay	Panlabs	232030
GR Human Glucocorticoid NHR Cell Based Agonist Nuclear Translocation Assay	DiscoverX	86-0013P-2446AG
GR Human Glucocorticoid NHR Cell Based Agonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2454AG
GR Human Glucocorticoid NHR Cell Based Agonist Protein-Protein Interaction Assay	SAFETYscan - DiscoverX	87-1002-2454AG
GR Human Glucocorticoid NHR Cell Based Antagonist Nuclear Translocation Assay	DiscoverX	86-0013P-2446AN
GR Human Glucocorticoid NHR Cell Based Antagonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2454AN
GR Human Glucocorticoid NHR Cell Based Antagonist Protein-Protein Interaction Assay	SAFETYscan - DiscoverX	87-1002-2454AN
GR Human Glucocorticoid NHR Cell Based PAM Nuclear Translocation Assay	DiscoverX	86-0013P-2446PM
GR Human Glucocorticoid NHR Cell Based PAM Protein-Protein Interaction Assay	DiscoverX	86-0003P-2454PM
GR Human Glucocorticoid NHR Functional Agonist & Antagonist Coactivator Assay	Panlabs	313050
GR Human Glucocorticoid NHR Functional Agonist Coactivator Assay	Panlabs	313050-0
GR Human Glucocorticoid NHR Functional Antagonist Coactivator Assay	Panlabs	313050-1
LXRalpha Human Liver X Receptor-Like NHR Binding (Agonist Radioligand) Assay	Cerep	4467
LXRalpha Human Liver X Receptor-Like NHR Cell Based Agonist Nuclear Translocation Assay	DiscoverX	86-0013P-2447AG
LXRalpha Human Liver X Receptor-Like NHR Cell Based Agonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2455AG
LXRalpha Human Liver X Receptor-Like NHR Cell Based Antagonist Nuclear Translocation Assay	DiscoverX	86-0013P-2447AN
LXRalpha Human Liver X Receptor-Like NHR Cell Based Antagonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2455AN
LXRalpha Human Liver X Receptor-Like NHR Cell Based PAM Nuclear Translocation Assay	DiscoverX	86-0013P-2447PM
LXRalpha Human Liver X Receptor-Like NHR Cell Based PAM Protein-Protein Interaction Assay	DiscoverX	86-0003P-2455PM
LXRalpha Human Liver X Receptor-Like NHR Functional Agonist & Antagonist Coactivator Assay	Cerep	G217
LXRalpha Human Liver X Receptor-Like NHR Functional Agonist & Antagonist Coactivator Assay	Panlabs	331810
LXRalpha Human Liver X Receptor-Like NHR Functional Agonist Coactivator Assay	Cerep	3488
LXRalpha Human Liver X Receptor-Like NHR Functional Agonist Coactivator Assay	Panlabs	331810-0
LXRalpha Human Liver X Receptor-Like NHR Functional Antagonist Coactivator Assay	Cerep	3489
LXRalpha Human Liver X Receptor-Like NHR Functional Antagonist Coactivator Assay	Panlabs	331810-1
LXRbeta Human Liver X Receptor-Like NHR Binding (Agonist Radioligand) Assay	Cerep	4468
LXRbeta Human Liver X Receptor-Like NHR Cell Based Agonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2456AG
LXRbeta Human Liver X Receptor-Like NHR Cell Based Antagonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2456AN
LXRbeta Human Liver X Receptor-Like NHR Cell Based PAM Protein-Protein Interaction Assay	DiscoverX	86-0003P-2456PM
LXRbeta Human Liver X Receptor-Like NHR Functional Agonist & Antagonist Coactivator Assay	Cerep	G218
LXRbeta Human Liver X Receptor-Like NHR Functional Agonist & Antagonist Coactivator Assay	Panlabs	331820
LXRbeta Human Liver X Receptor-Like NHR Functional Agonist Coactivator Assay	Cerep	3490
LXRbeta Human Liver X Receptor-Like NHR Functional Agonist Coactivator Assay	Panlabs	331820-0
LXRbeta Human Liver X Receptor-Like NHR Functional Antagonist Coactivator Assay	Cerep	3491
LXRbeta Human Liver X Receptor-Like NHR Functional Antagonist Coactivator Assay	Panlabs	331820-1
LXRbeta-NCoR1 Human Liver X Receptor-Like NHR Cell Based Agonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2457AG
LXRbeta-NCoR1 Human Liver X Receptor-Like NHR Cell Based Antagonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2457AN
LXRbeta-NCoR1 Human Liver X Receptor-Like NHR Cell Based PAM Protein-Protein Interaction Assay	DiscoverX	86-0003P-2457PM
MCR Human Aldosterone NHR Cell Based Agonist Nuclear Translocation Assay	DiscoverX	86-0013P-2448AG
MCR Human Aldosterone NHR Cell Based Agonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2458AG
MCR Human Aldosterone NHR Cell Based Antagonist Nuclear Translocation Assay	DiscoverX	86-0013P-2448AN
MCR Human Aldosterone NHR Cell Based Antagonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2458AN
MCR Human Aldosterone NHR Cell Based PAM Nuclear Translocation Assay	DiscoverX	86-0013P-2448PM
MCR Human Aldosterone NHR Cell Based PAM Protein-Protein Interaction Assay	DiscoverX	86-0003P-2458PM
nhrMAX NHR Panel	DiscoverX	86-0117
PPARalpha Human NHR Binding (Agonist Radioligand) Assay	Cerep	640
PPARalpha Human NHR Cell Based Agonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2459AG
PPARalpha Human NHR Cell Based Antagonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2459AN
PPARalpha Human NHR Cell Based PAM Protein-Protein Interaction Assay	DiscoverX	86-0003P-2459PM
PPARalpha Human NHR Functional Agonist & Antagonist Coactivator Assay	Cerep	G131
PPARalpha Human NHR Functional Agonist & Antagonist Coactivator Assay	Panlabs	338210
PPARalpha Human NHR Functional Agonist Coactivator Assay	Cerep	2811
PPARalpha Human NHR Functional Agonist Coactivator Assay	Panlabs	338210-0
PPARalpha Human NHR Functional Antagonist Coactivator Assay	Cerep	2813
PPARalpha Human NHR Functional Antagonist Coactivator Assay	Panlabs	338210-1
PPARdelta Human NHR Cell Based Agonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2461AG
PPARdelta Human NHR Cell Based Antagonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2461AN
PPARdelta Human NHR Cell Based PAM Protein-Protein Interaction Assay	DiscoverX	86-0003P-2461PM
PPARdelta Human NHR Functional Agonist & Antagonist Coactivator Assay	Cerep	G149
PPARdelta Human NHR Functional Agonist Coactivator Assay	Cerep	3082
PPARdelta Human NHR Functional Antagonist Coactivator Assay	Cerep	3083
PPARgamma Human NHR Binding (Agonist Radioligand) Assay	Cerep	641
PPARgamma Human NHR Binding (Agonist Radioligand) Assay	Panlabs	267500
PPARgamma Human NHR Cell Based Agonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2460AG
PPARgamma Human NHR Cell Based Antagonist Protein-Protein Interaction Assay	DiscoverX	86-0003-2460AN
PPARgamma Human NHR Cell Based Antagonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2460AN
PPARgamma Human NHR Cell Based PAM Protein-Protein Interaction Assay	DiscoverX	86-0003P-2460PM
PPARgamma Human NHR Functional Agonist & Antagonist Coactivator Assay	Cerep	G124
PPARgamma Human NHR Functional Agonist & Antagonist Coactivator Assay	Panlabs	338250
PPARgamma Human NHR Functional Agonist Coactivator Assay	Cerep	2771
PPARgamma Human NHR Functional Agonist Coactivator Assay	Panlabs	338250-0
PPARgamma Human NHR Functional Antagonist Coactivator Assay	Cerep	2772
PPARgamma Human NHR Functional Antagonist Coactivator Assay	Panlabs	338250-1
PR Human Progesterone NHR Binding (Agonist Radioligand) Assay	Cerep	2341
PR Human Progesterone NHR Binding (Agonist Radioligand) Assay	Panlabs	299005
PR Human Progesterone NHR Functional Agonist & Antagonist Coactivator Assay	Cerep	G128
PR Human Progesterone NHR Functional Agonist & Antagonist Coactivator Assay	Panlabs	338270
PR Human Progesterone NHR Functional Agonist Coactivator Assay	Cerep	2855
PR Human Progesterone NHR Functional Agonist Coactivator Assay	Panlabs	338270-0
PR Human Progesterone NHR Functional Antagonist Coactivator Assay	Cerep	2860
PR Human Progesterone NHR Functional Antagonist Coactivator Assay	Panlabs	338270-1
PRa Human Progesterone NHR Cell Based Agonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2462AG
PRa Human Progesterone NHR Cell Based Antagonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2462AN
PRa Human Progesterone NHR Cell Based PAM Protein-Protein Interaction Assay	DiscoverX	86-0003P-2462PM
PRb Human Progesterone NHR Cell Based Agonist Nuclear Translocation Assay	DiscoverX	86-0013P-2449AG
PRb Human Progesterone NHR Cell Based Agonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2463AG
PRb Human Progesterone NHR Cell Based Antagonist Nuclear Translocation Assay	DiscoverX	86-0013P-2449AN
PRb Human Progesterone NHR Cell Based Antagonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2463AN
PRb Human Progesterone NHR Cell Based PAM Nuclear Translocation Assay	DiscoverX	86-0013P-2449PM
PRb Human Progesterone NHR Cell Based PAM Protein-Protein Interaction Assay	DiscoverX	86-0003P-2463PM
PXR Human NHR Binding (Agonist Radioligand) Assay	Cerep	2538
PXR Human NHR Cell Based Agonist Reporter Assay	Panlabs	338100-0
PXR Human NHR Functional Agonist & Antagonist Coactivator Assay	Cerep	G225
PXR Human NHR Functional Agonist Coactivator Assay	Cerep	3140
PXR Human NHR Functional Antagonist Coactivator Assay	Cerep	3144
RARalpha Human Retinoic Acid NHR Binding (Agonist Radioligand) Assay	Cerep	2084
RARalpha Human Retinoic Acid NHR Binding (Agonist Radioligand) Assay	Panlabs	269200
RARalpha Human Retinoic Acid NHR Cell Based Agonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2464AG
RARalpha Human Retinoic Acid NHR Cell Based Antagonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2464AN
RARalpha Human Retinoic Acid NHR Cell Based PAM Protein-Protein Interaction Assay	DiscoverX	86-0003P-2464PM
RARalpha Human Retinoic Acid NHR Functional Agonist & Antagonist Coactivator Assay	Panlabs	338600
RARalpha Human Retinoic Acid NHR Functional Agonist Coactivator Assay	Panlabs	338600-0
RARalpha Human Retinoic Acid NHR Functional Antagonist Coactivator Assay	Panlabs	338600-1
RARgamma Human Retinoic Acid NHR Binding (Agonist Radioligand) Assay	Panlabs	269400
RARgamma Human Retinoic Acid NHR Functional Agonist & Antagonist Coactivator Assay	Panlabs	338800
RARgamma Human Retinoic Acid NHR Functional Agonist Coactivator Assay	Panlabs	338800-0
RARgamma Human Retinoic Acid NHR Functional Antagonist Coactivator Assay	Panlabs	338800-1
RXRalpha Human Retinoid X NHR Binding (Agonist Radioligand) Assay	Cerep	3678
RXRalpha Human Retinoid X NHR Binding (Agonist Radioligand) Assay	Panlabs	269500
RXRalpha Human Retinoid X NHR Cell Based Agonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2466AG
RXRalpha Human Retinoid X NHR Cell Based Antagonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2466AN
RXRalpha Human Retinoid X NHR Cell Based PAM Protein-Protein Interaction Assay	DiscoverX	86-0003P-2466PM
RXRalpha Human Retinoid X NHR Functional Agonist & Antagonist Coactivator Assay	Panlabs	338900
RXRalpha Human Retinoid X NHR Functional Agonist Coactivator Assay	Panlabs	338900-0
RXRalpha Human Retinoid X NHR Functional Antagonist Coactivator Assay	Panlabs	338900-1
RXRbeta Human Retinoid X NHR Binding (Agonist Radioligand) Assay	Panlabs	269540
RXRbeta Human Retinoid X NHR Functional Agonist & Antagonist Coactivator Assay	Panlabs	338940
RXRbeta Human Retinoid X NHR Functional Agonist Coactivator Assay	Panlabs	338940-0
RXRbeta Human Retinoid X NHR Functional Antagonist Coactivator Assay	Panlabs	338940-1
RXRgamma Human Retinoid X NHR Cell Based Agonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2467AG
RXRgamma Human Retinoid X NHR Cell Based Antagonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2467AN
RXRgamma Human Retinoid X NHR Cell Based PAM Protein-Protein Interaction Assay	DiscoverX	86-0003P-2467PM
TR (Non-Selective) Rat Thyroid Hormone NHR Binding (Agonist Radioligand) Assay	Panlabs	285900
TR β Human Thyroid Hormone NHR Binding (Agonist Radioligand) Assay	Panlabs	285940
TRalpha Human Thyroid Hormone NHR Cell Based Agonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2468AG
TRalpha Human Thyroid Hormone NHR Cell Based Antagonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2468AN
TRalpha Human Thyroid Hormone NHR Cell Based PAM Protein-Protein Interaction Assay	DiscoverX	86-0003P-2468PM
TRalpha Human Thyroid Hormone NHR Functional Agonist Coactivator Assay	Panlabs	356600-0
TRbeta Human Thyroid Hormone NHR Cell Based Agonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2469AG
TRbeta Human Thyroid Hormone NHR Cell Based Antagonist Protein-Protein Interaction Assay	DiscoverX	86-0003P-2469AN
TRbeta Human Thyroid Hormone NHR Cell Based PAM Protein-Protein Interaction Assay	DiscoverX	86-0003P-2469PM
TRbeta Human Thyroid Hormone NHR Functional Agonist Coactivator Assay	Panlabs	356700-0
VDR Human NHR Binding (Agonist Radioligand) Assay	Panlabs	288010
VDR Human NHR Functional Agonist & Antagonist Coactivator Assay	Cerep	G215
VDR Human NHR Functional Agonist Coactivator Assay	Cerep	3484
VDR Human NHR Functional Agonist Coactivator Assay	Panlabs	364900-0
VDR Human NHR Functional Antagonist Coactivator Assay	Cerep	3485