MyD88 L265P Antibody | 고마바이오텍

특징 

• MyD88 L265P는 B cell 림프종에서 발견되는 가장 흔한 driver mutation 중 하나로, 예후가 좋지 않습니다. L265P 돌연변이는 Waldenström’s macroglobulinemia (WM)의 90%, IgM monoclonal gammopathy of undetermined significance (IgM-MGUS)의 50-80%, 미만성 거대 B세포 림프종 (DLBCL)의 29%에서 자주 발생합니다. 현재까지 WM 및 공격적인 DLBCL은 치료가 불가능한 상태로 남아 있습니다. 종양 특이적 MyD88 L265P 돌연변이는 유용한 예후 지표이자 새로운 치료 타겟입니다. 
• MyD88 L265P 돌연변이는 BTK, HCK, NFkB 및 JAK-STAT3의 활성화를 통해 발암성 신호 전달을 촉진합니다.
• NFkB 및 JAK-STAT3 활동을 확인하기 위한 MyD88 L265P 항체를 제공합니다. 

주요 제품 

anti-MyD88 L265P antibody [SQab30311] (#ARG67041)  

• Product Description : Recombinant rabbit Monoclonal antibody [SQab30311] recognizes MyD88 L265P
• Tested Reactivity : Hu
• Tested Application : IHC-P
• Specificity : This antibody is specifically for detects MyD88 L265P mutation
• Host : Rabbit
• Clonality : Monoclonal
• Clone : SQab30311
• Isotype : IgG
• Target Name : MyD88 L265P
• Antigen Species : Human
• Immunogen : Synthetic peptide of Human MyD88 (L265P)

anti-MyD88 antibody (#ARG54348)

• Product Description : Rabbit Polyclonal antibody recognizes MyD88
• Tested Reactivity : Hu, Ms, Rat
• Tested Application : WB
• Specificity : This antibody recognizes human and mouse MyD88 (35 kD).
• Host : Rabbit
• Clonality : Polyclonal
• Isotype : IgG
• Target Name : MyD88
• Antigen Species : Human
• Immunogen : Synthetic peptide (18aa) within the last 50 aa of Human MyD88. The sequence is identical to that of mouse MyD88. 

anti-MyD88 antibody (#ARG41275)

• Product Description : Rabbit Polyclonal antibody recognizes MyD88
• Tested Reactivity : Hu, Ms, Rat
• Tested Application : FACS, IHC-P, WB
• Host : Rabbit
• Clonality : Polyclonal
• Isotype : IgG
• Target Name : MyD88
• Antigen Species : Human
• Immunogen : Recombinant protein corresponding to A44-F264 of Human MyD88.

anti-MyD88 antibody (#ARG54347)

• Product Description : Rabbit Polyclonal antibody recognizes MyD88
• Tested Reactivity : Hu
• Tested Application : FACS, ICC/IF, IHC-P, WB
• Specificity : This antibody recognizes human and mouse MyD88 (35 kD).
• Host : Rabbit
• Clonality : Polyclonal
• Isotype : IgG
• Target Name : MyD88
• Antigen Species : Human
• Immunogen : Peptide corresponding to aa 233-248 of human MyD88. The sequence differs from mouse MyD88 by two amino acids.

anti-MyD88 antibody (#ARG63727)

• Product Description : Goat Polyclonal antibody recognizes MyD88
• Tested Reactivity : Hu
• Predict Reactivity : Ms, Rat, Dog
• Tested Application : ELISA, IHC-P, WB
• Host : Goat
• Clonality : Polyclonal
• Isotype IgG
• Target Name : MyD88
• Antigen Species : Human
• Immunogen : C-IKYKAMKKEFP