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제품 상세
Esterase Inhibitors 이미지

Esterase Inhibitors

Esterase의 효소활성에 관여하는 inhibitor를 소개합니다. (Autotaxin, Cholinesterases, Exonucleases, Inositol-requiring enzyme 1 (IRE1), Lipases, Phospholipases)

프린트 제품 문의

특징 

 

  • Esterases는 ester 결합의 가수분해를 촉진하여 acid와 alcohol을 형성하는 효소입니다. 
  • Autotaxin은 nucleotide pyrophosphatase-phosphodiesterase 2 (NPP2)라고도 하며, lysophospholipase D 활성을 갖는 secreted enzyme으로 lysophosphatidic acid (LPA)을 생성하는 주요 효소입니다. 
  • Inositol-requiring enzyme 1 (IRE1)은 transmembrane ER 단백질로, 단백질의 misfolding에 관여하는 효소입니다. 
  • Lipase는 hydrophobic lipid에서 ester bond의 가수분해를 촉진하는 효소입니다. diacylglycerol lipase (DAGL)과 lipoprotein lipase (LPL), endothelial lipase (LIPG)등이 이 그룹에 속합니다.


주요 제품 

 

Autotaxin
Cat. No. Product Activity
4196 HA 130 Potent and selective autotaxin inhibitor
4078 PF 8380 Potent autotaxin inhibitor
Cholinesterases
Cat. No. Product Activity
0388 Ambenonium dichloride Cholinesterase inhibitor
4385 Donepezil hydrochloride Potent AChE inhibitor
0686 Galanthamine hydrobromide Cholinesterase inhibitor
0622 Physostigmine hemisulfate Cholinesterase inhibitor
4440 Rivastigmine tartrate Dual AChE and BChE inhibitor
Exonucleases
Cat. No. Product Activity
3190 Mirin Inhibitor of MRN exonuclease activity
Inositol-requiring enzyme 1 (IRE1)
Cat. No. Product Activity
4479 4μ8C Inhibits IRE1α endoribonuclease activity
6166 AMG 18 hydrochloride Potent and selective IRE1α inhibitor
6009 B I09 IRE1 endonuclease inhibitor; cell permeable
4509 STF 083010 Inhibits IRE1α endonuclease activity
Lipases
Cat. No. Product Activity
3752 GSK 264220A Endothelial lipase and lipoprotein lipase inhibitor
3540 Orlistat Pancreatic, gastric and carboxylester lipase inhibitor
1842 RHC 80267 Diacylglycerol lipase inhibitor
Phospholipases
Cat. No. Product Activity
1462 AACOCF3 Phospholipase A2 inhibitor
6316 ASB 14780 Potent and selective cytosolic phospholipase A2 alpha (cPLA2α) inhibitor; active in vivo
1437 D609 Selective PC-PLC inhibitor
6755 Darapladib Potent lp-PLA2 inhibitor
7462 ET 18-OCH3 Selective PI-PLC inhibitor, also PAF receptor agonist
3600 FIPI Phospholipase D inhibitor
7407 LEI 401 High affinity N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) inhibitor
1941 m-3M3FBS Phospholipase C activator
4894 ML 299 Potent inhibitor of PLD1 and PLD2; CNS penetrant
1942 o-3M3FBS Inactive analog of m-3M3FBS (Cat. No. 1941)
1842 RHC 80267 Diacylglycerol lipase inhibitor. Weak inhibitor of PLC and PLA2
1268 U 73122 Phospholipase C inhibitor
4133 U 73343 Analog of U 73122 (Cat. No. 1268)
3575 VU 0155069 Potent and selective PLD1 inhibitor
4171 VU 0364739 hydrochloride Potent and selective PLD2 inhibitor
2522 YM 26734 Secretory phospholipase A2 (sPLA2) inhibitor

 

주문정보

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS
Donepezil hydrochloride (10 mg) 4385 10 mg TOCRIS
Donepezil hydrochloride (50 mg) 4385 50 mg TOCRIS
Galanthamine hydrobromide (100 mg) 0686 100 mg TOCRIS
Physostigmine hemisulfate (10 MG) 0622 10 mg TOCRIS
Rivastigmine tartrate (50 mg) 4440 50 mg TOCRIS
4mu8C (10 mg) 4479 10 mg TOCRIS
4mu8C (50 mg) 4479 50 mg TOCRIS
AMG 18 hydrochloride (5 MG) 6166 5 mg TOCRIS
ASB 14780 (5 MG) 6316 5 mg TOCRIS
B I09 (10 MG) 6009 10 mg TOCRIS
B I09 (50 MG) 6009 50 mg TOCRIS
D609 (10 mg) 1437 10 mg TOCRIS
D609 (50 mg) 1437 50 mg TOCRIS
Darapladib (10 MG) 6755 10 mg TOCRIS
ET 18-OCH3 7462 10 mg TOCRIS
FIPI (10 mg) 3600 10 mg TOCRIS
FIPI (50 mg) 3600 50 mg TOCRIS
GSK 264220A (10 mg) 3752 10 mg TOCRIS
GSK 264220A (50 mg) 3752 50 mg TOCRIS
HA 130 (10 mg) 4196 10 mg TOCRIS
HA 130 (50 mg) 4196 50 mg TOCRIS
LEI 401 (10 MG) 7407 10 MG TOCRIS
m-3M3FBS (10 mg) 1941 10 mg TOCRIS
Mirin (10 mg) 3190 10 mg TOCRIS
Mirin (50 mg) 3190 50 mg TOCRIS
ML 299 4894 2 mg TOCRIS
o-3M3FBS (10 mg) 1942 10 mg TOCRIS
Orlistat (10 mg) 3540 10 mg TOCRIS
Orlistat (50 mg) 3540 50 mg TOCRIS
RHC 80267 (10 mg) 1842 10 mg TOCRIS
RHC 80267 (50 mg) 1842 50 mg TOCRIS
STF 083010 (10 mg) 4509 10 mg TOCRIS
STF 083010 (50 mg) 4509 50 mg TOCRIS
U 73343 (10 mg) 4133 10 mg TOCRIS
U 73343 (50 mg) 4133 50 mg TOCRIS
VU 0155069 (10 mg) 3575 10 mg TOCRIS
VU 0155069 (50 mg) 3575 50 mg TOCRIS
VU 0364739 hydrochloride (10 mg) 4171 10 mg TOCRIS
VU 0364739 hydrochloride (50 mg) 4171 50 mg TOCRIS
YM 26734 (10 mg) 2522 10 mg TOCRIS
전체보기
Maker
TOCRIS
Cat.No.
4385
Product
Donepezil hydrochloride (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4385
Product
Donepezil hydrochloride (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
0686
Product
Galanthamine hydrobromide (100 mg)
Size
100 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
0622
Product
Physostigmine hemisulfate (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4440
Product
Rivastigmine tartrate (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4479
Product
4mu8C (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4479
Product
4mu8C (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6166
Product
AMG 18 hydrochloride (5 MG)
Size
5 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6316
Product
ASB 14780 (5 MG)
Size
5 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6009
Product
B I09 (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6009
Product
B I09 (50 MG)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
1437
Product
D609 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
1437
Product
D609 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6755
Product
Darapladib (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7462
Product
ET 18-OCH3
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3600
Product
FIPI (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3600
Product
FIPI (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3752
Product
GSK 264220A (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3752
Product
GSK 264220A (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4196
Product
HA 130 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4196
Product
HA 130 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7407
Product
LEI 401 (10 MG)
Size
10 MG
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
1941
Product
m-3M3FBS (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3190
Product
Mirin (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3190
Product
Mirin (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4894
Product
ML 299
Size
2 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
1942
Product
o-3M3FBS (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3540
Product
Orlistat (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3540
Product
Orlistat (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
1842
Product
RHC 80267 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
1842
Product
RHC 80267 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4509
Product
STF 083010 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4509
Product
STF 083010 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4133
Product
U 73343 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4133
Product
U 73343 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3575
Product
VU 0155069 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3575
Product
VU 0155069 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4171
Product
VU 0364739 hydrochloride (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4171
Product
VU 0364739 hydrochloride (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
2522
Product
YM 26734 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
전체보기

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주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS

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MSDS

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