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제품 상세
Histone Demethylases (KDM) Inhibitor | Histone Deacetylase (HDAC) Inhibitor 이미지

Histone Demethylases (KDM) Inhibitor | Histone Deacetylase (HDAC) Inhibitor

KDM, HDAC등 Histone의 아미노산 잔기에 작용하는 효소그룹에 대한 inhibitor를 제공합니다.

프린트 제품 문의

특징 

 

  • Histone demethylases (KDMs)은 histone tail에 있는 lysine과 arginine 잔기로부터 methyl group을 제거하는 효소입니다. 
  • Histone Deacetylase (HDAC)은 histone tail에 있는 lysine 잔기로부터 acetyl group을 제거하는 효소입니다. 염색질의 리모델링에 관여하며 세포주기, 혈관형성, 면역조절, 세포사멸등에 관여합니다. 

 

 

주요 제품  

 

Histone Demethylases
Cat. No. Product Activity
6124 (R)-2-Hydroxyglutaric acid disodium salt KDM4A inhibitor; also NF-κB activator
6384 Ciclopirox Pan-histone demethylase inhibitor
4593 GSK J1 Potent JMJD3/UTX inhibitor
4688 GSK J2 Inactive isomer of GSK J1 (Cat. No. 4593)
4594 GSK J4 Histone KDM inhibitor; cell permeable
5361 GSK LSD 1 dihydrochloride Potent and selective LSD1 inhibitor
4464 IOX 1 Histone demethylase inhibitor; cell permeable
4972 JIB 04 Pan Jumonji inhibitor; active in vivo
7676 JQKD 82 dihydrochloride Selective inhibitor of lysine demethylase 5
5287 NSC 636819 KDM4A/KDM4B inhibitor
6244 OG-L002 Potent LSD1 inhibitor
4977 RN 1 dihydrochloride LSD1 inhibitor
5714 S 2101 LSD1 inhibitor
5089 TC-E 5002 Selective KDM2/7 inhibitor
3852 Tranylcypromine hydrochloride Irreversible inhibitor of LSD1; also inhibits MAO
Histone Deacetylases - Class I HDACs
Cat. No. Product Activity
2952 CI 994 Class I histone deacetylase inhibitor; orally active
3515 FK 228 Potent and selective class I histone deacetylase inhibitor; antitumor
4643 PCI 34051 Potent and selective HDAC8 inhibitor
4902 NSC 405020 Histone deacetylase inhibitor
5727 MC 1742 Potent class I and IIb HDAC inhibitor
6208 MS 275 HDAC (Class I) inhibitor
6284 BRD 73954 Dual histone deacetylase (HDAC) 6/8 inhibitor
6728 RGFP 966 Potent and selective HDAC3 inhibitor
7191 Santacruzamate A Highly potent and selective HDAC2 inhibitor
Histone Deacetylases - Class II HDACs
Cat. No. Product Activity
6284 BRD 73954 Dual histone deacetylase (HDAC) 6/8 inhibitor
6040 BRD 9757 Potent and selective HDAC6 inhibitor
6725 CHDI 00390576 Potent and selective class IIa HDAC inhibitor; brain penetrant
4830 LMK 235 Selective HDAC4/HDAC5 inhibitor
4077 MC 1568 Selective HDAC class IIa inhibitor
5727 MC 1742 Potent class I and IIb HDAC inhibitor
7051 Tasquinimod High affinity HDAC4 negative allosteric modulator; also binds S100A9; antiangiogenic
3402 Tubacin HDAC6 inhibitor; inhibits α-tubulin deacetylation
6270 Tubastatin A hydrochloride Potent HDAC6 inhibitor
Histone Deacetylases - Class III HDACs
Cat. No. Product Activity
4754 AK 7 Selective SIRT2 inhibitor; brain penetrant
7137 Cambinol SIRT1 and SIRT2 inhibitor
2780 EX 527 Selective SIRT1 inhibitor
4590 Honokiol SIRT3 activator; also blocks NF-κB activation
4106 Nicotinamide SIRT1 inhibitor; promotes hematopoietic progenitor proliferation; also PARP-1 inhibitor
1418 Resveratrol SIRT1 activator
5457 SirReal 2 Selective inhibitor of SIRT2
3521 Sirtinol Selective sirtuin family deacetylase inhibitor
7558 SRT 1720 Selective SIRT1 activator; induces autophagy and mitochondrial biogenesis
Histone Deacetylases - Non-selective HDACs
Cat. No. Product Activity
6249 Givinostat hydrochloride Histone deacetylase inhibitor
7629 Panobinostat Pan-histone deacetylase inhibitor
4652 SAHA Class I and II HDAC inhibitor
2421 Scriptaid Histone deacetylase inhibitor
2682 Sodium 4-Phenylbutyrate Histone deacetylase inhibitor
3850 Sodium butyrate Histone deacetylase inhibitor
1406 Trichostatin A Potent histone deacetylase inhibitor
2815 Valproic acid, sodium salt Histone deacetylase inhibitor

 

주문정보

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS
Tubacin (1 mg) 3402 1 mg TOCRIS
(R)-2-Hydroxyglutaric acid disodium salt (50 mg) 6124 50 mg TOCRIS
AK 7 (10 mg) 4754 10 mg TOCRIS
AK 7 (50 mg) 4754 50 mg TOCRIS
Belinostat 7981 50 mg TOCRIS
Belinostat 7981 10 mg TOCRIS
BRD 73954 (10 MG) 6284 10 mg TOCRIS
BRD 73954 (50 MG) 6284 50 mg TOCRIS
Cambinol 7137 10 mg TOCRIS
Cambinol 7137 50 mg TOCRIS
CHDI 00390576 (5 MG) 6725 5 mg TOCRIS
CHDI 00484077 7879 5 mg TOCRIS
EX 527 (1 mg) 2780 1 mg TOCRIS
EX 527 (10 mg) 2780 10 mg TOCRIS
EX 527 (50 mg) 2780 50 mg TOCRIS
FK 228 (1 mg) 3515 1 mg TOCRIS
Givinostat hydrochloride (25 MG) 6249 25 mg TOCRIS
Givinostat hydrochloride (5 MG) 6249 5 mg TOCRIS
GSK J1 (10 mg) 4593 10 mg TOCRIS
GSK J1 (50 mg) 4593 50 mg TOCRIS
GSK J2 (10 mg) 4688 10 mg TOCRIS
GSK J2 (50 mg) 4688 50 mg TOCRIS
GSK J4 (10 mg) 4594 10 mg TOCRIS
GSK J4 (50 mg) 4594 50 mg TOCRIS
GSK LSD 1 dihydrochloride (10 mg) 5361 10 mg TOCRIS
GSK LSD 1 dihydrochloride (50 mg) 5361 50 mg TOCRIS
Honokiol (10 mg) 4590 10 mg TOCRIS
Honokiol (50 mg) 4590 50 mg TOCRIS
IOX 1 (10 mg) 4464 10 mg TOCRIS
IOX 1 (50 mg) 4464 50 mg TOCRIS
JIB 04 (10 mg) 4972 10 mg TOCRIS
JIB 04 (50 mg) 4972 50 mg TOCRIS
JQKD 82 dihydrochloride 7676 5 mg TOCRIS
MC 1568 (10 mg) 4077 10 mg TOCRIS
MC 1568 (50 mg) 4077 50 mg TOCRIS
MC 1742 (10 mg) 5727 10 mg TOCRIS
MS 275 (10 MG) 6208 10 mg TOCRIS
MS 275 (50 MG) 6208 50 mg TOCRIS
Nicotinamide (50 mg) 4106 50 mg TOCRIS
NSC 405020 (10 mg) 4902 10 mg TOCRIS
NSC 405020 (50 mg) 4902 50 mg TOCRIS
NSC 636819 (10 mg) 5287 10 mg TOCRIS
NSC 636819 (50 mg) 5287 50 mg TOCRIS
OG-L002 (25 MG) 6244 25 mg TOCRIS
OG-L002 (5 MG) 6244 5 mg TOCRIS
Panobinostat 7629 10 mg TOCRIS
Panobinostat 7629 50 mg TOCRIS
RGFP 966 (25 MG) 6728 25 mg TOCRIS
RGFP 966 (5 MG) 6728 5 mg TOCRIS
RN 1 dihydrochloride (10 mg) 4977 10 mg TOCRIS
전체보기
Maker
TOCRIS
Cat.No.
3402
Product
Tubacin (1 mg)
Size
1 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6124
Product
(R)-2-Hydroxyglutaric acid disodium salt (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4754
Product
AK 7 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4754
Product
AK 7 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7981
Product
Belinostat
Size
50 mg
Qty
Data Sheet
Maker
TOCRIS
Cat.No.
7981
Product
Belinostat
Size
10 mg
Qty
Data Sheet
Maker
TOCRIS
Cat.No.
6284
Product
BRD 73954 (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6284
Product
BRD 73954 (50 MG)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7137
Product
Cambinol
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7137
Product
Cambinol
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6725
Product
CHDI 00390576 (5 MG)
Size
5 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7879
Product
CHDI 00484077
Size
5 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
2780
Product
EX 527 (1 mg)
Size
1 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
2780
Product
EX 527 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
2780
Product
EX 527 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
3515
Product
FK 228 (1 mg)
Size
1 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6249
Product
Givinostat hydrochloride (25 MG)
Size
25 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6249
Product
Givinostat hydrochloride (5 MG)
Size
5 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4593
Product
GSK J1 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4593
Product
GSK J1 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4688
Product
GSK J2 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4688
Product
GSK J2 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4594
Product
GSK J4 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4594
Product
GSK J4 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5361
Product
GSK LSD 1 dihydrochloride (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5361
Product
GSK LSD 1 dihydrochloride (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4590
Product
Honokiol (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4590
Product
Honokiol (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4464
Product
IOX 1 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4464
Product
IOX 1 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4972
Product
JIB 04 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4972
Product
JIB 04 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7676
Product
JQKD 82 dihydrochloride
Size
5 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4077
Product
MC 1568 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4077
Product
MC 1568 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5727
Product
MC 1742 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6208
Product
MS 275 (10 MG)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6208
Product
MS 275 (50 MG)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4106
Product
Nicotinamide (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4902
Product
NSC 405020 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4902
Product
NSC 405020 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5287
Product
NSC 636819 (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
5287
Product
NSC 636819 (50 mg)
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6244
Product
OG-L002 (25 MG)
Size
25 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6244
Product
OG-L002 (5 MG)
Size
5 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7629
Product
Panobinostat
Size
10 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
7629
Product
Panobinostat
Size
50 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6728
Product
RGFP 966 (25 MG)
Size
25 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
6728
Product
RGFP 966 (5 MG)
Size
5 mg
Qty
Data Sheet
MSDS
Maker
TOCRIS
Cat.No.
4977
Product
RN 1 dihydrochloride (10 mg)
Size
10 mg
Qty
Data Sheet
MSDS
전체보기

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주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS

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 0.5 ml Elite Pre-stained Protein Ladder (2 x 0.25 ml) PAL-EPL-500 0.5ml 500
Maker
Cat.No.
Product
Size
Qty
Data Sheet
MSDS

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