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Histone Demethylases |
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Cat. No. |
Product Name |
Activity |
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6124 |
(R)-2-Hydroxyglutaric
acid disodium salt |
KDM4A inhibitor; also NF-κB activator |
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6384 |
Ciclopirox |
Pan-histone demethylase inhibitor |
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4593 |
GSK
J1 |
Potent JMJD3/UTX inhibitor |
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4688 |
GSK
J2 |
Inactive isomer of GSK J1 (Cat. No. 4593) |
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4594 |
GSK
J4 |
Histone KDM inhibitor; cell permeable |
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5361 |
GSK LSD 1 dihydrochloride |
Potent and selective LSD1 inhibitor |
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4464 |
IOX
1 |
Histone demethylase inhibitor; cell permeable |
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4972 |
JIB
04 |
Pan Jumonji inhibitor; active in
vivo |
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7676 |
JQKD 82 dihydrochloride |
Selective inhibitor of lysine demethylase 5 |
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5287 |
NSC 636819 |
KDM4A/KDM4B inhibitor |
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6244 |
OG-L002 |
Potent LSD1 inhibitor |
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4977 |
RN 1 dihydrochloride |
LSD1 inhibitor |
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5714 |
S 2101 |
LSD1 inhibitor |
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5089 |
TC-E 5002 |
Selective KDM2/7 inhibitor |
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3852 |
Tranylcypromine
hydrochloride |
Irreversible inhibitor of LSD1; also inhibits MAO |
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Histone Deacetylases - Class I HDACs |
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Cat. No. |
Product Name |
Activity |
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2952 |
CI 994 |
Class I histone deacetylase inhibitor; orally active |
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3515 |
FK 228 |
Potent and selective class I histone deacetylase
inhibitor; antitumor |
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4643 |
PCI 34051 |
Potent and selective HDAC8 inhibitor |
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4902 |
NSC 405020 |
Histone deacetylase inhibitor |
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5727 |
MC 1742 |
Potent class I and IIb HDAC inhibitor |
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6208 |
MS 275 |
HDAC (Class I) inhibitor |
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6284 |
BRD 73954 |
Dual histone deacetylase (HDAC) 6/8 inhibitor |
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6728 |
RGFP 966 |
Potent and selective HDAC3 inhibitor |
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7191 |
Santacruzamate A |
Highly potent and selective HDAC2 inhibitor |
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Histone Deacetylases - Class II HDACs |
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Cat. No. |
Product Name |
Activity |
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6284 |
BRD 73954 |
Dual histone deacetylase (HDAC) 6/8 inhibitor |
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6040 |
BRD 9757 |
Potent and selective HDAC6 inhibitor |
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6725 |
CHDI 00390576 |
Potent and selective class IIa HDAC inhibitor; brain
penetrant |
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4830 |
LMK 235 |
Selective HDAC4/HDAC5 inhibitor |
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4077 |
MC 1568 |
Selective HDAC class IIa inhibitor |
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5727 |
MC 1742 |
Potent class I and IIb HDAC inhibitor |
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7051 |
Tasquinimod |
High affinity HDAC4 negative allosteric modulator;
also binds S100A9; antiangiogenic |
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3402 |
Tubacin |
HDAC6 inhibitor; inhibits α-tubulin deacetylation |
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6270 |
Tubastatin A hydrochloride |
Potent HDAC6 inhibitor |
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Histone Deacetylases - Class III HDACs |
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Cat. No. |
Product Name |
Activity |
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4754 |
AK 7 |
Selective SIRT2 inhibitor; brain penetrant |
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7137 |
Cambinol |
SIRT1 and SIRT2 inhibitor |
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2780 |
EX 527 |
Selective SIRT1 inhibitor |
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4590 |
Honokiol |
SIRT3 activator; also blocks NF-κB activation |
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4106 |
Nicotinamide |
SIRT1 inhibitor; promotes hematopoietic progenitor
proliferation; also PARP-1 inhibitor |
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1418 |
Resveratrol |
SIRT1 activator |
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5457 |
SirReal 2 |
Selective inhibitor of SIRT2 |
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3521 |
Sirtinol |
Selective sirtuin family deacetylase inhibitor |
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7558 |
SRT 1720 |
Selective SIRT1 activator; induces autophagy and
mitochondrial biogenesis |
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Histone Deacetylases - Non-selective HDACs |
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Cat. No. |
Product Name |
Activity |
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6249 |
Givinostat hydrochloride |
Histone deacetylase inhibitor |
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7629 |
Panobinostat |
Pan-histone deacetylase inhibitor |
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4652 |
SAHA |
Class I and II HDAC inhibitor |
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2421 |
Scriptaid |
Histone deacetylase inhibitor |
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2682 |
Sodium 4-Phenylbutyrate |
Histone deacetylase inhibitor |
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3850 |
Sodium butyrate |
Histone deacetylase inhibitor |
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1406 |
Trichostatin A |
Potent histone deacetylase inhibitor |
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2815 |
Valproic acid, sodium salt |
Histone deacetylase inhibitor |