고마바이오텍(주)

로그인이 필요합니다.

Category 전체보기
전기영동 > 단백질 전기영동 전기영동 > 헥산 전기영동
Cat. No.전체보기

검색 결과가 없습니다.

Product전체보기

검색 결과가 없습니다.

Brand전체보기

검색 결과가 없습니다.

제품 상세
바이오시밀러의 3차원 구조 비교분석 PCA-ELISA 이미지

바이오시밀러의 3차원 구조 비교분석 PCA-ELISA

PCA (Protein Conformation Array) ELISA Kit은 오리지널 drug을 구성하는 펩타이드시퀀스에 대한 항체 panel로 구성된 ELISA로, 바이오시밀러의 protein folding, 글리코실화, 3D 구조를 규명하는데 이용됩니다.

프린트 제품 문의

특징 

 

  • 바이오시밀러는 오리지널 바이오의약품과 동일한 유전자를 사용하더라도 복제 벡터, 발현 시스템, 발효 및 정제를 포함한 생산의 차이에 의해 일반적으로 항상 원본과 약간 다른 바이오시밀러가 생산되므로, 오리지날 의약품과의 유사성, 동등성을 체크해야 합니다.  
  • PCA (Protein Conformation Array)-ELISA는 알려진 항체의약품의 full length protein 시퀀스를 구성하는 multiple 펩타이드에 대한 multiple 항체들로 코팅된 ELISA plate 입니다. 
  • 제대로 folding된 단백질은 3차원 구조를 형성하여 대부분의 antigenicity가 가려져 제한된 수의 항체만 반응하게 되는 반면, 제대로 접히지 않은 단백질은 펩타이드 서열이 노출되어 항체에 의해 인식됩니다. 따라서 이러한 지문 (fingerprint)을 통해 오리지널 drug과 바이오시밀러의 형태의 차이를 비교할 수 있습니다. 
  • 오리지널 의약품의 아미노산 서열 전체에 걸쳐있는 겹치는 펩타이드에 대한 30-31개의 polyclonal 항체로 코팅되어 있으며, 3개의 96well plate를 제공합니다. 
  • 가려져 있는 epitope에 대해 만들어진 항체 배열로 인해, 단백질 구조의 매우 작은 변화나 변성을 민감하게 감지할 수 있습니다. 
  • 하나의 바이오시밀러를 Innovator와 세 번 비교하거나 두 개의 바이오시밀러를 Innovator와 중복으로 비교할 수 있습니다.
 

 arraybridge-sequence 

  

 

구성 

 

  • Coated Clear 96 Well Plates
  • 5x Dilution Buffer
  • 10x PBS-T
  • Reporting antibody
  • Streptavidin-HRP Conjugate
  • TMB Substrate
  • Stop Solution
  • Plate Sealer

  

 

종류 

 

Drug 바이오시밀러 ELISA Kit 
Aflibercept AfliBridge ELISA 
Avastin AvaBridge ELISA 
Campath CampBridge ELISA 
Enbrel EnbrBridge ELISA 
Erbitux ErbiBridge ELISA 
Erythropoietin EpoBridge ELISA 
Filgrastim or Pegfilgrastim FilBridge ELISA 
Herceptin HercBridge ELISA 
Humira HumiBridge ELISA 
Lucentis LuceBridge ELISA 
Prolia DenoBridge ELISA 
Remicade RemiBridge ELISA 
Rituxin RituBridge ELISA 
Simponi GoliBridge ELISA 
Somavert SomaBridge ELISA 
Stelara UsteBridge ELISA 
Synagis SynaBridge ELISA 

 

 

 

주문정보

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS
AfliBridge ELISA (for Aflibercept Biosimilar comparison) AB000218 5PK ARRAY BRIDGE
AfliBridge ELISA (for Aflibercept Biosimilar comparison) AB000218 1PK ARRAY BRIDGE
AvaBridge ELISA (for Avastin Biosimilar comparison) AB000201 1PK ARRAY BRIDGE
AvaBridge ELISA (for Avastin Biosimilar comparison) AB000201 5PK ARRAY BRIDGE
CampBridge ELISA (for Campath Biosimilar comparison) AB000203 5PK ARRAY BRIDGE
CampBridge ELISA (for Campath Biosimilar comparison) AB000203 1PK ARRAY BRIDGE
DenoBridge ELISA (for Prolia Biosimilar comparison) AB000213 5PK ARRAY BRIDGE
DenoBridge ELISA (for Prolia Biosimilar comparison) AB000213 1PK ARRAY BRIDGE
EnbrBridge ELISA (for Enbrel Biosimilar comparison) AB000211 1PK ARRAY BRIDGE
EnbrBridge ELISA (for Enbrel Biosimilar comparison) AB000211 5PK ARRAY BRIDGE
EpoBridge ELISA (for Erythropoietin Biosimilar comparison) AB000210 5PK ARRAY BRIDGE
EpoBridge ELISA (for Erythropoietin Biosimilar comparison) AB000210 1PK ARRAY BRIDGE
ErbiBridge ELISA (for Erbitux Biosimilar comparison) AB000202 5PK ARRAY BRIDGE
ErbiBridge ELISA (for Erbitux Biosimilar comparison) AB000202 1PK ARRAY BRIDGE
FilBridge ELISA (for Filgrastim or Pegfilgrastim Biosimilar comparison) AB000212 1PK ARRAY BRIDGE
FilBridge ELISA (for Filgrastim or Pegfilgrastim Biosimilar comparison) AB000212 5PK ARRAY BRIDGE
GoliBridge ELISA (for Simponi Biosimilar comparison) AB000215 1PK ARRAY BRIDGE
GoliBridge ELISA (for Simponi Biosimilar comparison) AB000215 5PK ARRAY BRIDGE
HercBridge ELISA (for Herceptin Biosimilar comparison) AB000207 5PK ARRAY BRIDGE
HercBridge ELISA (for Herceptin Biosimilar comparison) AB000207 1PK ARRAY BRIDGE
HumiBridge ELISA (for Humira Biosimilar comparison) AB000205 1PK ARRAY BRIDGE
HumiBridge ELISA (for Humira Biosimilar comparison) AB000205 5PK ARRAY BRIDGE
LuceBridge ELISA (for Lucentis Biosimilar comparison) AB000214 5PK ARRAY BRIDGE
LuceBridge ELISA (for Lucentis Biosimilar comparison) AB000214 1PK ARRAY BRIDGE
RemiBridge ELISA (for Remicade Biosimilar comparison) AB000209 5PK ARRAY BRIDGE
RemiBridge ELISA (for Remicade Biosimilar comparison) AB000209 1PK ARRAY BRIDGE
RituBridge ELISA (for Rituxin Biosimilar comparison) AB000204 5PK ARRAY BRIDGE
RituBridge ELISA (for Rituxin Biosimilar comparison) AB000204 1PK ARRAY BRIDGE
SomaBridge ELISA (for Somavert Biosimilar comparison) AB000217 1PK ARRAY BRIDGE
SomaBridge ELISA (for Somavert Biosimilar comparison) AB000217 5PK ARRAY BRIDGE
SynaBridge ELISA (for Synagis Biosimilar comparison) AB000206 5PK ARRAY BRIDGE
SynaBridge ELISA (for Synagis Biosimilar comparison) AB000206 1PK ARRAY BRIDGE
UsteBridge ELISA (for Stelara Biosimilar comparison) AB000216 5PK ARRAY BRIDGE
UsteBridge ELISA (for Stelara Biosimilar comparison) AB000216 1PK ARRAY BRIDGE
MouseBridge ELISA AB000221 5PK ARRAY BRIDGE
MouseBridge ELISA AB000221 1PK ARRAY BRIDGE
p53Bridge ELISA AB000219 1PK ARRAY BRIDGE
p53Bridge ELISA AB000219 5PK ARRAY BRIDGE
RabBridge ELISA AB000222 5PK ARRAY BRIDGE
RabBridge ELISA AB000222 1PK ARRAY BRIDGE
SHP2Bridge ELISA AB000220 5PK ARRAY BRIDGE
SHP2Bridge ELISA AB000220 1PK ARRAY BRIDGE
InnoBridge ELISA (for novel monoclonal antibody and other biosimilars with the same Fc sequence) AB000208 5PK ARRAY BRIDGE
InnoBridge ELISA (for novel monoclonal antibody and other biosimilars with the same Fc sequence) AB000208 1PK ARRAY BRIDGE
전체보기
Maker
ARRAY BRIDGE
Cat.No.
AB000218
Product
AfliBridge ELISA (for Aflibercept Biosimilar comparison)
Size
5PK
Qty
Maker
ARRAY BRIDGE
Cat.No.
AB000218
Product
AfliBridge ELISA (for Aflibercept Biosimilar comparison)
Size
1PK
Qty
Maker
ARRAY BRIDGE
Cat.No.
AB000201
Product
AvaBridge ELISA (for Avastin Biosimilar comparison)
Size
1PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000201
Product
AvaBridge ELISA (for Avastin Biosimilar comparison)
Size
5PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000203
Product
CampBridge ELISA (for Campath Biosimilar comparison)
Size
5PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000203
Product
CampBridge ELISA (for Campath Biosimilar comparison)
Size
1PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000213
Product
DenoBridge ELISA (for Prolia Biosimilar comparison)
Size
5PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000213
Product
DenoBridge ELISA (for Prolia Biosimilar comparison)
Size
1PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000211
Product
EnbrBridge ELISA (for Enbrel Biosimilar comparison)
Size
1PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000211
Product
EnbrBridge ELISA (for Enbrel Biosimilar comparison)
Size
5PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000210
Product
EpoBridge ELISA (for Erythropoietin Biosimilar comparison)
Size
5PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000210
Product
EpoBridge ELISA (for Erythropoietin Biosimilar comparison)
Size
1PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000202
Product
ErbiBridge ELISA (for Erbitux Biosimilar comparison)
Size
5PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000202
Product
ErbiBridge ELISA (for Erbitux Biosimilar comparison)
Size
1PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000212
Product
FilBridge ELISA (for Filgrastim or Pegfilgrastim Biosimilar comparison)
Size
1PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000212
Product
FilBridge ELISA (for Filgrastim or Pegfilgrastim Biosimilar comparison)
Size
5PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000215
Product
GoliBridge ELISA (for Simponi Biosimilar comparison)
Size
1PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000215
Product
GoliBridge ELISA (for Simponi Biosimilar comparison)
Size
5PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000207
Product
HercBridge ELISA (for Herceptin Biosimilar comparison)
Size
5PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000207
Product
HercBridge ELISA (for Herceptin Biosimilar comparison)
Size
1PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000205
Product
HumiBridge ELISA (for Humira Biosimilar comparison)
Size
1PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000205
Product
HumiBridge ELISA (for Humira Biosimilar comparison)
Size
5PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000214
Product
LuceBridge ELISA (for Lucentis Biosimilar comparison)
Size
5PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000214
Product
LuceBridge ELISA (for Lucentis Biosimilar comparison)
Size
1PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000209
Product
RemiBridge ELISA (for Remicade Biosimilar comparison)
Size
5PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000209
Product
RemiBridge ELISA (for Remicade Biosimilar comparison)
Size
1PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000204
Product
RituBridge ELISA (for Rituxin Biosimilar comparison)
Size
5PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000204
Product
RituBridge ELISA (for Rituxin Biosimilar comparison)
Size
1PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000217
Product
SomaBridge ELISA (for Somavert Biosimilar comparison)
Size
1PK
Qty
Maker
ARRAY BRIDGE
Cat.No.
AB000217
Product
SomaBridge ELISA (for Somavert Biosimilar comparison)
Size
5PK
Qty
Maker
ARRAY BRIDGE
Cat.No.
AB000206
Product
SynaBridge ELISA (for Synagis Biosimilar comparison)
Size
5PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000206
Product
SynaBridge ELISA (for Synagis Biosimilar comparison)
Size
1PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000216
Product
UsteBridge ELISA (for Stelara Biosimilar comparison)
Size
5PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000216
Product
UsteBridge ELISA (for Stelara Biosimilar comparison)
Size
1PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000221
Product
MouseBridge ELISA
Size
5PK
Qty
Maker
ARRAY BRIDGE
Cat.No.
AB000221
Product
MouseBridge ELISA
Size
1PK
Qty
Maker
ARRAY BRIDGE
Cat.No.
AB000219
Product
p53Bridge ELISA
Size
1PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000219
Product
p53Bridge ELISA
Size
5PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000222
Product
RabBridge ELISA
Size
5PK
Qty
Maker
ARRAY BRIDGE
Cat.No.
AB000222
Product
RabBridge ELISA
Size
1PK
Qty
Maker
ARRAY BRIDGE
Cat.No.
AB000220
Product
SHP2Bridge ELISA
Size
5PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000220
Product
SHP2Bridge ELISA
Size
1PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000208
Product
InnoBridge ELISA (for novel monoclonal antibody and other biosimilars with the same Fc sequence)
Size
5PK
Qty
Data Sheet
Maker
ARRAY BRIDGE
Cat.No.
AB000208
Product
InnoBridge ELISA (for novel monoclonal antibody and other biosimilars with the same Fc sequence)
Size
1PK
Qty
Data Sheet
전체보기

추천제품

관련제품

주문정보 - Cat No, PRODUCT, SIZE, 수량 등 항목으로 구성되어있습니다.
  Product Cat.No. Size Maker Qty Data Sheet MSDS

자료

웨비나/Video

TOP

제품 문의

 0.5 ml Elite Pre-stained Protein Ladder (2 x 0.25 ml) PAL-EPL-500 0.5ml 500
Maker
Cat.No.
Product
Size
Qty
Data Sheet
MSDS

로그인

로그인