Lipidomics 분석서비스 | Lipidomics Analysis Service | 고마바이오텍

특징

• 세포, 조직, 장기, 혈액, 미생물, 피부각질 등 다양한 시료 내 존재하는 lipid를 동정하고 정량 분석해 드립니다.
• Lipid 추출부터 시료처리, 분석까지 자동화된 분석시스템으로 6주 이내에 분석결과를 제공합니다. 
• Lipidomics를 통한 각 지질종과 농도의 고해상도 분석결과는 질환이나 생물학적 상태의 현상에 대한 통찰력을 제시합니다.
• 모든 지질을 한번에 측정함으로써 포괄적인 통계 분석이 가능합니다. (Lipidome)
  
• LipotypeZoom을 이용하여 data를 시각화하고 다양한 종류의 그래픽 통계분석 자료를 제공합니다.
  
• GMP 인증 시설에서 분석이 진행되므로 신뢰할 수 있는 데이터 품질을 제공합니다. 모든 샘플에 내부 표준을 사용하며 샘플 수집, 보관 관련 품질 문제를 신속하게 감지할 수 있습니다. 
  

• 4200종 이상의 individual lipids에 대해 66 lipid classes 및 species 또는 subspecies 레벨에서 정량분석합니다. 
• 분석이 까다로운 cholesterol 과 15종 이상의 glycospinglipids도 분석이 가능합니다. 
  
• Cell & tissue/Plasma/Skin 등 시료타입에 적합한 lipid class coverage로 분석패키지를 제공합니다. 
  
• 예) PC (lipid class)> PC 34:0 (species) > PC 18:0_16:0 + fatty acid information (subspecies)

• Tissues and organs (liver, brain, etc.) 
• Cultured cells 및 세포 소기관 (subcellular compartments) 
• Body fluids, blood and plasma
• Bacteria, yeast 등 microorganisms
• Skin tapes

 

3) GMP 인증 기술 기반의 분석데이터 제공 

• 고해상도 mass 분석장비인 Lipotype Explorer를 이용하여 소량의 (small amount) 시료를 단 시간에 high-throughput으로 정량분석합니다. 
• 시료의 추출부터 processing, data 분석까지 자동화된, GMP인증을 받은 shotgun lipidomics 분석기술은 대량의 시료분석에도 안정적이고, 재현성이 높은 분석결과를 제공합니다.
• Lipid 바이오마커 동정 및 drug Discovery 등 제약분야에 활용할 수 있습니다.
  
• 각 lipid class에 대한 class-specific internal standard를 통해 정확한 분석결과를 보장합니다. 

Package:	Basic Analysis (academic only)	Standard Analysis	Premium Analysis
Delivery:	6 weeks	6 weeks	4 weeks
Minimum:	10 samples	15 samples	20 samples
Structural Details:	Species	Species/Subspecies	Species/Subspecies
Approach:	Untargeted using LipotypeXplorer	Untargeted using LipotypeXplorer	Untargeted using LipotypeXplorer
Result:	Quantitative	Quantitative	Quantitative
Standard Data Report:	YES	YES	YES
Basic Coverage:	PA - phosphatidate PC - phosphatidylcholine PE - phosphatidylethanolamine PG - phosphatidylglycerol PI - phosphatidylinositol PS - phosphatidylserine DAG - diacylglycerol TAG - triacylglycerol SM - sphingomyelin• CE - cholesteryl ester• EE - ergosteryl ester•• • - animals •• - yeast	PA - phosphatidate PC - phosphatidylcholine PE - phosphatidylethanolamine PG - phosphatidylglycerol PI - phosphatidylinositol PS - phosphatidylserine DAG - diacylglycerol TAG - triacylglycerol SM - sphingomyelin• CE - cholesteryl ester• EE - ergosteryl ester•• • - animals •• - yeast	PA - phosphatidate PC - phosphatidylcholine PE - phosphatidylethanolamine PG - phosphatidylglycerol PI - phosphatidylinositol PS - phosphatidylserine DAG - diacylglycerol TAG - triacylglycerol SM - sphingomyelin• CE - cholesteryl ester• EE - ergosteryl ester•• • - animals •• - yeast
Extended Coverage:	N/A	LPA - lyso-phosphatidate LPC - lyso-phosphatidylcholine LPE - lyso-phosphatidylethanolamine LPG - lyso-phosphatidylglycerol LPI - lyso-phosphatidylinositol LPS - lyso-phosphatidylserine PC O- - ether-linked PC• PE O- - ether-linked PE• LPC O- - ether-linked LPC• LPE O- - ether-linked LPE• Cer - ceramide HexCer - hexosylceramide• CL - cardiolipin • - animals	LPA - lyso-phosphatidate LPC - lyso-phosphatidylcholine LPE - lyso-phosphatidylethanolamine LPG - lyso-phosphatidylglycerol LPI - lyso-phosphatidylinositol LPS - lyso-phosphatidylserine PC O- - ether-linked PC• PE O- - ether-linked PE• LPC O- - ether-linked LPC• LPE O- - ether-linked LPE• Cer - ceramide HexCer - hexosylceramide• CL - cardiolipin • - animals
Free Sterol Coverage:	N/A	N/A	Free cholesterol or ergosteroly y - yeast only
Glycosphingolipid Coverage:	N/A	N/A	GM1 GM2 GM3 GM4 GD1 GD2 GD3 GT1 GT2 GT3 GQ1 Gb3 Gb4 Sulf - sulfatide DiHexCer - dihexosylceramide
Yeast Specific Coverage:	N/A	N/A	IPC - inositolphosphorylceramide MIPC - mannosyl-inositol phosphorylceramide M(IP)2C - mannosyl-di-(inositolphosphoryl) ceramide CDP-DAG - CDP-diacylglycerol
Sample Amount Adjustment:	N/A	Samples are pre-tested to ensure that the most optimal amounts are used for analysis.	Samples are pre-tested to ensure that the most optimal amounts are used for analysis.
Extended Data Report:	Optional	Optional	Included
Turbo Delivery:	N/A	Optional (3 weeks)	Optional (2 weeks)
Personal Support:	N/A	N/A	Available

 

   

• BLOOD PLASMA/SERUM  

Package:	Standard Analysis	Premium Analysis	Ultimate Analysis
Delivery Time:	6 weeks	8 weeks	Inquire
Minimum:	15 samples	250 samples	500 samples
Structural Details:	Species	Species/Subspecies	Species/Subspecies
Approach:	Untargeted using LipotypeXplorer	Untargeted using LipotypeXplorer	Untargeted using LipotypeXplorer
Result:	Quantitative	Quantitative	Quantitative
Standard Data Report:	YES	YES	YES
Lipid Coverage:	DAG - diacylglycerol TAG - triacylglycerol PC - phosphatidylcholine PE - phosphatidylethanolamine PI - phosphatidylinositol LPC - lyso-phosphatidylcholine LPE - lyso-phosphatidylethanolamine PC O- - ether-linked PC PE O- - ether-linked PE LPC O- - ether-linked LPC LPE O- - ether-linked LPE Cer - ceramide HexCer - hexosylceramide SM - sphingomyelin Chol - cholesterol CE - cholesteryl ester	DAG - diacylglycerol TAG - triacylglycerol PC - phosphatidylcholine PE - phosphatidylethanolamine PI - phosphatidylinositol LPC - lyso-phosphatidylcholine LPE - lyso-phosphatidylethanolamine PC O- - ether-linked PC PE O- - ether-linked PE LPC O- - ether-linked LPC LPE O- - ether-linked LPE Cer - ceramide HexCer - hexosylceramide SM - sphingomyelin Chol - cholesterol CE - cholesteryl ester	DAG - diacylglycerol TAG - triacylglycerol PC - phosphatidylcholine PE - phosphatidylethanolamine PI - phosphatidylinositol LPC - lyso-phosphatidylcholine LPE - lyso-phosphatidylethanolamine PC O- - ether-linked PC PE O- - ether-linked PE LPC O- - ether-linked LPC LPE O- - ether-linked LPE Cer - ceramide HexCer - hexosylceramide SM - sphingomyelin Chol - cholesterol CE - cholesteryl ester
Personal Support:	N/A	Available	Available
Porject Support:	N/A	N/A	Available
Turbo Delivery:	Optional (3 weeks)	Optional (4 weeks)	Inquire
Extended Data Report:	Optional	Included	Included
Interactive Data Visualization & Analysis:	Free of charge with extended report	Included (optional)	Included (optional)
Statistical Report:	N/A	Included	Included

  

  

사용 논문

• lipid 분석은 다양한 연구의 신뢰도를 입증하는 자료로 이용됩니다.
• Inflammation, Neuroscience, Pharma, Cancer, Cosmetics 등 다양한 분야에서 이용된 사례를 참고하세요. (아래 이미지를 누르면 관련 논문을 확인하실 수 있습니다.)

연구별 적용 사례 & 웨비나 

Note: This service is for Research Use Only. Not for use in diagnostic procedures. 

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