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KOMA Mini-Catalog

  • KOMA Inhibitor Book

    총 4900여개의 Small Molecules이 수록되어 있습니다.

  • KOMA Neuroscience

    Neuroscience 관련 Kit, 항체, biochemical 등의 제품이 소개되어 있는 미니 카달로그입니다.

  • KOMA Drug Discovery & Development

    신약개발연구를 위한 Kinase, Ion channel, GPCR 관련 제품과 서비스 내용이 수록되어 있습니다.


    다양한 분야의 ELISA kit와 Assay Kit 목록이 수록된 미니카탈로그 입니다.

  • KOMA Virus Expression and Gene Delivery

    아데노바이러스, 렌티바이러스, AAV 서비스 및 제품이 소개되어 있는 미니 카달로그입니다.

  • KOMA Electrophoresis

    단백질 및 DNA 전기영동장치, pre-cast gel, Marker, 각종 reagent들이 소개되어 있는 미니 카달로그입니다.

  • KOMA PCR (Polymerase Chain Reaction)

    PCR 및 분자생물학 관련 제품들이 수록된 미니카탈로그 입니다.

  • KOMA Minicatalog

    전기영동, ELISA Kit, PCR Kit등의 고마 제품들이 수록된 미니카탈로그 입니다.


Immunology & Western Blot
  • ELISA Guide (PDF only)

    ELISA 실험에 대한 hint, tip, troubleshooting 등 자세한 가이드를 제공합니다.

  • Immunological Reagents for Research and Diagnostic Assay Development

    MP Biomedicals의 Monoclonal, Polyclonal Antibody 및 Purified Protein을 소개합니다.

  • Immunology Research (PDF only)

    Chemokine, Integrin, Cytokine Receptors 등에 대한 agonist, antagonist, inhibitor를 소개합니다.


  • Autophagy Poster (PDF Only)

    Autophagy is a cellular process used by cells for degradation and recycling. Written by Patricia Boya and Patrice Codogno, this poster summarizes the molecular machinery, physiology and pathology of autophagy. Compounds available from Tocris are listed.

  • Depression Poster (PDF Only)

    Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.

  • Angiogenesis in Cancer Poster (PDF Only)

    Adapted from the 2015 Cancer Product Guide, Edition 3, this poster summarizes the pathogenesis of angiogenesis in cancer, as well as some of the main angiogenesis therapeutic targets.

  • Addiction Poster (PDF Only)

    The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.

  • Alzheimer's Poster (PDF Only)

    Alzheimer's disease (AD) is a degenerative brain disease and the most common cause of dementia, affecting approximately 47 million people worldwide. Updated in 2015, this poster summarizes the structural and functional changes observed in the progression of this neurodegenerative disease, as well as classic AD drug targets.

  • Cancer Metabolism Poster (PDF Only)

    Adapted from the 2015 Cancer Product Guide, Edition 3, this poster summarizes the main targets for cancer metabolism researchers. Genetic changes and epigenetic modifications in cancer cells alter the regulation of cellular metabolic pathways. These distinct metabolic circuits could provide viable cancer therapeutic targets.

  • Cardiovascular Poster (PDF Only)

    Cardiovascular disease remains one of the major causes of morbidity and mortality in the Western world and therefore this therapeutic area continues to be of great interest to researchers. This poster highlights the key GPCRs regulating vascular reactivity.

  • Cell Cycle & DNA Damage Repair Poster (PDF Only)

    In normal cells, each stage of the cell cycle is tightly regulated, however in cancer cells many genes and proteins that are involved in the regulation of the cell cycle are mutated or over expressed. Adapted from the 2015 Cancer Product Guide, Edition 3, this poster summarizes the stages of the cell cycle and DNA repair. It also highlights strategies for enhancing replicative stress in cancer cells to force mitotic catastrophe and cell death.

  • Epigenetics in Cancer Poster (PDF Only)

    Adapted from the 2015 Cancer Product Guide Edition 3, this poster summarizes the main epigenetic targets in cancer. The dysregulation of epigenetic modifications has been shown to result in oncogenesis and cancer progression. Unlike genetic mutations, epigenetic alterations are considered to be reversible and thus make promising therapeutic targets.

  • Gut Hormones Poster (PDF Only)

    The gastrointestinal tract is the largest endocrine gland in the human body, secreting hormones that affect digestion, appetite and energy expenditure. Neuropeptide modulators and gut hormones that influence appetite are reviewed in this poster.

  • Huntington's Disease Poster (PDF Only)

    Huntington's disease (HD) is a monogenic neurodegenerative disorder, which is characterized by the prevalent loss of GABAergic medium spiny neurons (MSN) in the striatum. This poster summarizes the MSN intracellular signaling pathways implicated in the pathology of HD, as well as highlighting the use of iPSCs for HD modeling.

  • Learning & Memory Poster (PDF Only)

    Recognition memory enables us to make judgements about whether or not we have encountered a particular stimulus before. This poster outlines the cellular mechanisms underlying recognition memory and its links to long-term depression, as well as the use of pharmacological intervention to assess the role of neurotransmitters in recognition memory.

  • Multiple Sclerosis Poster (PDF Only)

    Multiple sclerosis (MS) is an autoimmune disease that is characterized by focal demyelination and axon degeneration in the central nervous system. This poster summarizes the neurobiology and current therapies of MS.

  • Pain Poster (PDF Only)

    Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.

  • Parkinson's Poster (PDF Only)

    Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.

  • Programmed Cell Death Poster (PDF Only)

    There are two currently recognized forms of programmed cell death: apoptosis and necroptosis. This poster summarizes the signaling pathways involved in apoptosis, necroptosis and cell survival following death receptor activation, and highlights the influence of the molecular switch, cFLIP, on cell fate.

  • Rheumatoid Arthritis Poster (PDF Only)

    Rheumatoid arthritis (RA) is a chronic destructive inflammatory autoimmune disease that results from a breakdown in immune tolerance, for reasons that are as yet unknown. This poster summarizes the pathology of RA and the inflammatory processes involved, as well as describing some of the epigenetic modifications associated with the disease and the potential for targeting these changes in the discovery of new treatments.

  • Schizophrenia Poster (PDF Only)

    Schizophrenia is a debilitating psychiatric disorder that affects 1% of the worldwide population. This poster describes the neurobiology of Schizophrenia, as well as highlighting the genetic and environmental factors that play a fundamental role in the etiology of the disease. The current and emerging drug targets are also discussed.

  • Cytokine Network

    Cytokine의 signaling pathway를 확인하세요.

  • Akt Pathway (PDF Only)

    The Akt signalling pathway plays a key role in the mediation of protein synthesis, metabolism, proliferation and cell cycle progression. It may be referred to as a 'prosurvival' pathway.

  • AMPK Pathway (PDF Only)

    AMPK signalling pathway plays an important role in the cellular reponse to low levels of available ATP, often caused by stresses such as heat shock, ischemia or hypoxia.

  • Apoptosis Pathway (PDF Only)

    Apoptosis is a physiological process for cell death that is critical during ageing and development. It may also be referred to as cell 'suicide'. Apoptosis can be triggered by events both inside and outside of the cell.

  • Estrogen Pathway (PDF Only)

    Estrogen is a steroid hormone that is responsible for the regulation of growth, differentiation and function of the reproductive system. Estrogen signalling is often dysregulated in breast cancer and osteoporosis.

  • Hedgehog Pathway (PDF Only)

    The Hedgehog (Hh) pathway is involved in development. It induces cellular proliferation and morphogenesis in developing tissues and organs. Hh signalling has been implicated in cancer.

  • Insulin Pathway (PDF Only)

    Signalling through the insulin pathway is fundamental for the regulation of intracellular glucose levels. This pathway can become dysregulated in diabetes.

  • JAK-STAT Pathway (PDF Only)

    The JAK-STAT signalling pathway has several roles, including the control of cell proliferation and hematopoiesis. It is the main signal transduction cascade from cytokine receptors.

  • MAPK Pathway (PDF Only)

    The mitogen-activated protein kinase pathway evokes an intracellular signalling cascade in response to extracellular stimuli such as heat and stress. It can influence cell division, metabolism and survival.

  • mTOR Pathway (PDF Only)

    mTOR is a serine/threonine kinase that nucleates at multiprotein complexes mTORC1 and mTORC2. Signalling by these complexes regulates cell growth, proliferation and survival.

  • NF-κB Pathway (PDF Only)

    NF-κB signalling plays an important role in inflammation, the innate and adaptive immune response and stress. Dysregulated signalling can occur in inflammatory and autoimmune diseases.

  • Notch Pathway (PDF Only)

    The Notch pathway is involved in determination of cell fate, regulation of pattern formation and other developmental settings. Disrupted signalling can cause developmental defects and a range of adult pathologies.

  • p53 Pathway (PDF Only)

    p53 signalling plays an important role in the co-ordination of the cellular response different types of stress such as DNA damage and hypoxia. The downstream signals lead to apoptosis, senescence and cell cycle arrest.

  • TGF-β Pathway (PDF Only)

    The TGF-β signalling pathway is involved in the regulation of growth and proliferation of cells along with migration, differentiation and apoptosis.

  • Toll-like Receptor Pathway (PDF Only)

    TLR signalling is involved in the cellular response to threatening molecules such as bacteria and viruses. It results in an inflammatory and immmunological response.

  • VEGF Pathway (PDF Only)

    TLR signalling is involved in the cellular response to threatening molecules such as bacteria and viruses. It results in an inflammatory and immmunological response.

  • Wnt Pathway (PDF Only)

    The Wnt pathway is involved in cellular differentiation and proliferation in adult tissues and also during embryogenesis. Disturbances within the pathway may lead to the formation of tumors and promote metastasis.

  • p53 Poster

    p53 tumour suppressor response에 대한 정보를 담았습니다.

  • Human Ion Channelome Poster

    Human Ion Channelome 정보를 담았습니다.

  • Human GPCRome Poster

    Human GPCRome 정보를 담았습니다.

  • Human Kinome Poster

    Human Kinome 정보를 담았습니다.