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 ǰȳ  Ű   Disease Pathway

Huntington's Disease Agonist & Antagonist

(Huntington 's disease, HD) Striatum GABA ߹迱 (MSN) ༺ ս Ư¡ ߻ Ű ༺ Դϴ. HD п MSN ȣ ο small molecule Ȯϼ.

TOCRIS
ǰ ϱ
μϱ

 


Target Cat. No Product Name
Adenosine A2A Receptors 1063 CGS 21680
5147 Istradefylline
2270
SCH 58261
1036
ZM 241385
Autophagy
1544
(±)-Bay K 8644
1334
Bafilomycin A1
1126
Dexamethasone
1130
LY 294002
1292
Rapamycin
1097
Taxol
1138
Thapsigargin
4247
Torin 1
3516
Tunicamycin
Caged compounds
2225
MNI caged kainic acid
2277
MNI-caged-D-aspartate
1490
MNI-caged-L-glutamate
2224
MNI-caged-NMDA
3992
NPEC-caged-dopamine
4932
RuBi-Dopa
3574
RuBi-Glutamate
Caspases 2251 Cisplatin
2166 Z-DEVD-FMK
2163 Z-VAD-FMK
Calpains 2950 Acetyl-Calpastatin (184-210) (human)
0448 Calpeptin
1269 PD 150606
Cathepsin 4863 CA 074
5208 E 64
4545 E 64d
1146 MDL 28170
Deubiquitinating Enzymes 4285 HBX 41108
5197 Spautin 1
Dopamine Receptors 3548 Dopamine
4349 Olanzapine
2865 Risperidone
0925 SCH 23390 
0922 SKF 38393 
2175 Tetrabenazine
Glutamate Transporters 3732 Ceftriaxone disodium salt
0111 Dihydrokainic acid
1223 DL-TBOA
5082 LDN 212320
2532 TFB-TBOA
Glutamate (Metabotropic) Receptors 0342 (RS)-3,5-DHPG
0805 (S)-3,5-DHPG
0337 (S)-MCPG
3235 CDPPB
3695 CHPG Sodium salt
0188 L-Quisqualic acid
2453 LY 379268
1212 MPEP 
2921 MTEP 
4323 VU 0360172 
Heat Shock Proteins 1515 17-AAG
1368 Geldanamycin
3803 VER 155008
Histone Acetyltransferases 3084 Anacardic acid
4200 C 646
4827 Garcinol
Histone Deacetylases 4652 SAHA
1406 Trichostatin A
IP3 Receptor 1280 (-)-Xestospongin C
1224 2-APB
iPSCs 4423 CHIR 99021
2815 Valproic acid, sodium salt
Kainate Receptors 0190 CNQX
0189 DNQX
0222 Kainic acid
3620 Topiramate
Matrix Metalloproteases 3268 Minocycline
Mitochondrial Permeability Transition Pore 1101 Cyclosporin A
2906 TRO 19622
Neural Stem Cell Differentiation 2634 DAPT
4126 DMH-1
3093 Dorsomorphin 
0927 Fluoxetine 
1099 Forskolin
2845 IBMX
4888 KHS 101 
5186 Neuropathiazol
4551 Purmorphamine
0695 Retinoic acid
4366 SAG
1614 SB 431542
3300 SU 5402
Neuroprotective compounds 5619 N-Acetylcysteine amide
0768 Riluzole
NMDA Receptors 0924 (+)-MK 801
0247 (R)-CPP
0173 (RS)-CPP
0106 D-AP5
0105 DL-AP5
0197 Homoquinolinic acid
0285 Ibotenic acid
0773 Memantine
0114 NMDA
2207 PDZ1 Domain inhibitor peptide
0225 Quinolinic acid
Proteasome 2267 Lactacystin
1748 MG 132
4045 PSI
SIRT 2780 EX 527
4106 Nicotinamide
1418 Resveratrol
Trk Receptors 3826 7,8-Dihydroxyflavone
4781 ANA 12
2837 BDNF (human)
4607 LM 22A4
Ubiquitin-activating Enzyme E1 2978 PYR 41
Ubiquitin/Ubl E2 Conjugating Enzyme 1744 Bay 11-7821
4858 NSC 697923
Ubiquitin E3 Ligases 3984 Nutlin-3
5076 SZL P1-41