• Home
  • About us
  • Log-In
  • Join Us
  • Sitemap
  • Recruit
ǰ/ Q&A
ڷû
Ŭ
A/S
Ŭ ȸ
 ǰȳ  ü,׿,ŶƮ   Cancer Research  Epigenetics

Recombinant Nucleosomes

Ŭ(Nucleosome) Chromatin ȣۿϰų ̸ Ű reader, writer, eraser ŸԴϴ. Epicypher Epigenetics study پ DNA Histone modification recombinant human nucleosome մϴ.

EpiCypher
ǰ ϱ
μϱ



  dCypher® Nucleosome Panels
  • combinatorially-modified nucleosome Ǿ ֽϴ.
  • 4 panel մϴ.
  • Binding domain protein assays, Enzyme activity assays, Antibody specificity validation ̿˴ϴ.
Cat# Panel Mononucleosomes Expressed histones
16-9001 Full  77 unique mononucleosomes two each of histones H2A, H2B, H3 and H4;
accession numbers: H2A-P04908, H2B-O60814, H3.1-P68431/H3.2-Q71DI3/H3.3-P84243, H4-P62805
16-9002 K-MetStat & OncoStat 24 unique mononucleosomes two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908, H2B-O60814, H3.1-P68431/H3.2-Q71DI3/H3.3-P84243, H4-P62805
16-9003 K-AcylStat 23 unique mononucleosomes two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908, H2B-O60814, H3.1-P68431/H3.2-Q71DI3, H4-P62805
16-9004  R-MetStat  15 unique mononucleosomes two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908, H2B-O60814, H3.1-P68431/H3.2-Q71DI3, H4-P62805

 

  Designer Nucleosome (dNucs™)
  • Histone Ư ġ ̹ acetylation, methylation PTM  recombinant nucleosome Դϴ.
  • Ÿ enzyme/protein substrate ̿ ֽϴ.
  • lot-to-lot variation  ݴϴ.
  • Free DNA Ե ʾ  ϴ.
  • Biotinylated, Non-biotinylated dNucs ֽϴ. 
  Recombinant Nucleosome (rNucs™)
  • PTM  Fully recombinant nucleosome Դϴ.
  • Inhibitor testing, enzyme assay ̿˴ϴ.
  Oncogenic Nucleosomes (oncoNucs™)
  • Ư histone ƹ̳⸦ mutation  ġȯ recombinant nucleosome Դϴ.
  • enzyme activity ־ mutation ȿ drug/inhibitor ȿ ͵ϴµ մϴ.
  Histone Variant Nucleosomes (vNucs™)
  • Histone varients ϰ ִ recombinant nucleosome Դϴ.
  Chromatin Remodeling Assay Substrate (EpiDyne™)
  • In vitro Nucleosome Remodeling (repositioning) ͸ ϴµ ̿Ǵ nucleosome Դϴ.
  • Histone ΰ ִ DNA 5' Cy3 óϰ, Histone octamer Cy5 󺧸Ǿϴ.
  • Histone octamer ġ ǰų ɶ Cy5 ҽǵǹǷ Cy3-Cy5 FRET Ȯմϴ.








rNucs Human Recombinant Nucleosomes, No PTMs
Cat. No. Product
16-0006  Mononucleosomes, biotinylated
16-0009  Mononucleosomes, non-biotinylated 
16-0023  Mononucleosomes, H3.1 ΔN2, biotinylated 
16-0016  Mononucleosomes, H3.1 ΔN32, biotinylated 
16-1016  Mononucleosomes, H3.1 ΔN32, non-biotinylated 
16-0017  Mononucleosomes, H3.3 ΔN32, biotinylated 
16-1017  Mononucleosomes, H3.3 ΔN32, non-biotinylated 
16-0018 Mononucleosomes, H4 ΔN15, biotinylated

dNucs Designer Recombinant Nucleosomes with PTMs
Lysine Methylation
Cat. No. Product
16-0321  H3K4me1, biotinylated
16-0334  H3K4me2, biotinylated 
16-1334  H3K4me2, non-biotinylated
16-0316  H3K4me3, biotinylated
16-1316  H3K4me3, non-biotinylated 
16-0325  H3K9me1, biotinylated 
16-0324  H3K9me2, biotinylated 
16-0315  H3K9me3, biotinylated
16-0338  H3K27me1, biotinylated
16-0339  H3K27me2, biotinylated
16-0317  H3K27me3, biotinylated
16-1317  H3K27me3, non-biotinylated 
16-0322  H3K36me1, biotinylated
16-0319  H3K36me2, biotinylated 
16-1319  H3K36me2, non-biotinylated
16-0320  H3K36me3, biotinylated
16-1320  H3K36me3, non-biotinylated 
16-0390  H3.3K36me3, biotinylated 
16-0367  H3K79me1, biotinylated 
16-0368  H3K79me2, biotinylated 
16-0369  H3K79me3, biotinylated
16-0393  H4K12me1, biotinylated 
16-0331  H4K20me1, biotinylated 
16-0332  H4K20me2, biotinylated 
16-0333  H4K20me3, biotinylated
16-1333 H4K20me3, non-biotinylated
Lysine Acetylation
Cat. No. Product
16-0386  H2BK12ac, biotinylated 
16-0387  H2BK20ac, biotinylated 
16-0342  H3K4ac, biotinylated 
16-0314  H3K9ac, biotinylated 
16-1314  H3K9ac, non-biotinylated 
16-0371  H3K9bu, biotinylated 
16-0351  H3K9cr, biotinylated 
16-0343  H3K14ac, biotinylated 
16-0372  H3K18ac, biotinylated 
16-0373  H3K18bu, biotinylated 
16-0337  H3K18cr, biotinylated 
16-0364  H3K23ac, biotinylated 
16-0365  H3K27ac, biotinylated 
16-1365  H3K27ac, non-biotinylated 
16-0384  H3K27bu, biotinylated 
16-0383  H3K27cr, biotinylated 
16-0385  H3K27ac, S28phos, biotinylated 
16-0378  H3K36ac, biotinylated 
16-0352  H4K5ac, biotinylated 
16-0353  H4K8ac, biotinylated 
16-0312  H4K12ac, biotinylated 
16-0354  H4K16ac, biotinylated 
16-0377  H4K20ac, biotinylated 
16-0376  H2AK5,9,13,15ac, biotinylated 
16-0336  H3K4,9,14,18ac, biotinylated 
16-0335  H3K4me3, K9,14,18ac, biotinylated 
16-0313  H4K5,8,12,16ac, biotinylated 
16-1313  H4K5,8,12,16ac, non-biotinylated 
16-0374 H3K4,9,14,18ac / H4K5,8,12,16ac, biotinylated 
Arginine Methylation
Cat. No. Product
16-0359  H2AR3me1, biotinylated 
16-0360  H2AR3me2a, biotinylated 
16-0361  H2AR3me2s, biotinylated 
16-0340  H3R2me1, biotinylated 
16-0341  H3R2me2a, biotinylated 
16-0355  H3R2me2s, biotinylated 
16-0379  H3R8me1, biotinylated 
16-0380  H3R8me2a, biotinylated 
16-0381  H3R8me2s, biotinylated 
16-0382  H3R17me1, biotinylated 
16-0375  H3R17me2a, biotinylated 
16-0356  H4R3me1, biotinylated 
16-0357  H4R3me2a, biotinylated 
16-0358 H4R3me2s, biotinylated 
Lysine Ubiquitination 
Cat. No. Product
16-0020  H2AUb1, biotinylated
16-0363  H2AK119ub, biotinylated
16-0370  H2BK120ub, biotinylated
16-0391 H3K14ub, biotinylated
Other PTMs
Cat. No. Product
16-0362  H3R2,8,17cit, biotinylated
16-1362  H3R2,8,17cit, non-biotinylated
16-0345  H3S10phos, biotinylated
16-1345  H3S10phos, non-biotinylated
16-0388  H3.1S28phos, biotinylated
16-0389 H3.3S31phos, biotinylated

vNucs Histone Variants
Cat. No. Product
16-0013  H2AX
16-1013  H2AX, non-biotinylated
16-0366  H2AXS139phos
16-0014  H2AZ.1
16-1014  H2AZ.1, non-biotinylated
16-0015  H2AZ.2
16-0011  H3.3
16-0012 H3.3, non-biotinylated 100 μg

oncoNucs AA Subs. in Cancer
Cat. No. Product
16-0349  H3.3K4M
16-0350  H3.3K9M
16-1323  H3.3K27M
16-0323  H3.3K27M, non-biotinylated
16-0347  H3.3G34V
16-0348  H3.3G34W
16-0344 H3.3K36M

Methyl DNA Nucs Nucleosomes with Methylated DNA
Cat. No. Product
16-2003  Mononucleosomes, Hemi-methylated, Biotinylated
16-2103  Mononucleosomes, Hemi-methylated
16-2004  Mononucleosomes, 187x601 DNA, Biotinylated
16-2104 Mononucleosomes, 187x601 DNA

EpiDyne® Chromatin Remodeling Assay Substrates
Cat. No. Product
16-4201  EpiDyne FRET Nucleosome Remodeling Assay Substrate
16-4101  EpiDyne Nucleosome Remodeling Assay Substrate ST601-GATC1
18-4100  EpiDyne Remodeling Assay Substrate DNA ST601-GATC0
18-4101 EpiDyne Remodeling Assay Substrate DNA ST601-GATC1



ֹ(Ordering Information)
CATNUM PRODUCT SIZE
16-0019Chicken Mononucleosomes, Purified50 ug
16-0022Chicken Polynucleosomes, Purified (HSW)50 ug
16-9003dCypher K-AcylStat Nucleosome Panel96 well plate
16-9002dCypher K-MetStat & OncoStat Nucleosome Panel96 well plate
16-9001dCypher Nucleosome Full Panel96 well plate
16-9004dCypher R-MetStat Nucleosome Panel96 well plate
16-4101EpiDyne Nucleosome Remodeling Assay Substrate ST601-GATC150 ug
16-4114EpiDyne Nucleosome Remodeling Assay Substrate ST601-GATC1, 50-N-66, Biotinylated50 ug
16-4111EpiDyne Nucleosome Remodeling Assay Substrate ST601-GATC1, Biotinylated50 ug
16-4115EpiDyne Nucleosome Remodeling Assay Substrate ST601-GATC1,2, 50-N-66, Biotinylated50 ug
16-4112EpiDyne Nucleosome Remodeling Assay Substrate ST601-GATC1,2, Biotinylated50 ug
16-4116EpiDyne Nucleosome Remodeling Assay Substrate ST601-GATC1,2,3, 50-N-66, Biotinylated50 ug
16-4113EpiDyne Nucleosome Remodeling Assay Substrate ST601-GATC1,2,3, Biotinylated50 ug
16-4201EpiDyne-FRET Nucleosome Remodeling Assay Substrate50 ug
16-0002HeLa Mononucleosomes, Purified50 ug
16-0003HeLa Polynucleosomes, Purified50 ug
16-8317Histone Ocatmer, Recombinant Human, H3K27me350 ug
16-0001Histone Octamer, Recombinant Human50 ug
16-2030Mononucleosome, (H3.1N32), 167x601 Biotinylated DNA, Recombinant Human50 ug
16-2130Mononucleosome, (H3.1N32), 167x601 DNA, Recombinant Human50 ug
16-2026Mononucleosome, (H3.1N32), 5' Cy5 167x601 DNA, Recombinant Human50 ug
16-2010Mononucleosome, 167x601 Biotinylated DNA, Recombinant Human50 ug
16-2110Mononucleosome, 167x601 DNA, Recombinant Human50 ug
16-2025Mononucleosome, 5' Cy5 167x601 DNA, Recombinant Human50 ug
16-1013Mononucleosomes (H2AX), Human Recombinant50 ug
16-0013Mononucleosomes (H2AX), Human Recombinant Biotinylated50 ug
16-0014Mononucleosomes (H2AZ.1), Human Recombinant Biotinylated50 ug
16-1014Mononucleosomes (H2AZ.1), Human Recombinant, Non-biotinylated50 ug
16-0015Mononucleosomes (H2AZ.2), Human Recombinant Biotinylated50 ug
16-1016Mononucleosomes (H3.1 N32), Human Recombinant50 ug
16-0023Mononucleosomes (H3.1N2), Recombinant Human, Biotinylated50 ug
16-0016Mononucleosomes (H3.1N32), Human Recombinant Biotinylated50 ug
16-0323Mononucleosomes (H3.3 K27M), Recombinant Human100ug
16-1017Mononucleosomes (H3.3 N32), Human Recombinant 50 ug
16-0017Mononucleosomes (H3.3 N32), Human Recombinant Biotinylated50 ug
16-0012Mononucleosomes (H3.3), Human Recombinant100 ug
16-0011Mononucleosomes (H3.3), Human Recombinant Biotinylated50 ug
16-0347Mononucleosomes (H3.3G34V), Recombinant Human Biotinylated50 ug
16-0348Mononucleosomes (H3.3G34W), Recombinant Human Biotinylated50 ug
16-1323Mononucleosomes (H3.3K27M), Recombinant Human, Biotinylated50 ug
16-0344Mononucleosomes (H3.3K36M), Recombinant Human Biotinylated50 ug
16-0349Mononucleosomes (H3.3K4M), Recombinant Human Biotinylated50 ug
16-0350Mononucleosomes (H3.3K9M), Recombinant Human Biotinylated50 ug
16-0018Mononucleosomes (H4 N15), Human Recombinant Biotinylated50 ug
16-0020Mononucleosomes H2A Ubiquityl, Recombinant Human, Biotinylated50 ug
16-0026Mononucleosomes, (H3.1 N32), Recombinant Human, 5' Cy550 ug
16-2134Mononucleosomes, (H3.1N32), Recombinant, 187x601 DNA50 ug
16-2034Mononucleosomes, (H3.1N32), Recombinant, 187x601 DNA, Biotinylated50 ug
16-0009Mononucleosomes, Recombinant Human100 ug
16-0006Mononucleosomes, Recombinant Human Biotinylated50 ug
16-0025Mononucleosomes, Recombinant Human, 5' Cy550 ug
16-0024Mononucleosomes, Recombinant Human, Desthiobiotinylated50 ug
16-3003Mononucleosomes, Recombinant, 177x601 DNA, Desthiobiotinylated50 ug
16-2104Mononucleosomes, Recombinant, 187x601 DNA50 ug
16-2004Mononucleosomes, Recombinant, 187x601 DNA, Biotinylated50 ug
16-2103Mononucleosomes, Recombinant, Hemi-methylated50 ug
16-2003Mononucleosomes, Recombinant, Hemi-methylated, Biotinylated50 ug
16-0363Nucleosome, Recombinant Human, H2AK119ub dNuc, Biotinylated50 ug
16-0359Nucleosome, Recombinant Human, H2AR3me1 dNuc, Biotinylated50 ug
16-0360Nucleosome, Recombinant Human, H2AR3me2a dNuc, Biotinylated50 ug
16-0366Nucleosome, Recombinant Human, H2AXS139phos dNuc, Biotinylated50 ug
16-0370Nucleosome, Recombinant Human, H2BK120ub dNuc, Biotinylated50 ug
16-0386Nucleosome, Recombinant Human, H2BK12ac dNuc, Biotinylated50 ug
16-0387Nucleosome, Recombinant Human, H2BK20ac dNuc, Biotinylated50 ug
16-1319Nucleosome, Recombinant Human, H3 K36me2 dNuc, Non-biotinylated50 ug
16-0388Nucleosome, Recombinant Human, H3.1S28phos dNuc, Biotinylated50 ug
16-0390Nucleosome, Recombinant Human, H3.3K36me3dNuc, Biotinylated50 ug
16-0389Nucleosome, Recombinant Human, H3.3S31phos dNuc, Biotinylated50 ug
16-0362Nucleosome, Recombinant Human, H3Cit2,8,17 dNuc, Biotinylated50 ug
16-1362Nucleosome, Recombinant Human, H3Cit2,8,17 dNuc, Non-Biotinylated50 ug
16-0343Nucleosome, Recombinant Human, H3K14ac dNuc, Biotinylated50 ug
16-0391Nucleosome, Recombinant Human, H3K14ub dNuc, Biotinylated50 ug
16-0372Nucleosome, Recombinant Human, H3K18ac dNuc, Biotinylated50 ug
16-0373Nucleosome, Recombinant Human, H3K18bu dNuc, Biotinylated50 ug
16-0337Nucleosome, Recombinant Human, H3K18cr dNuc, Biotinylated50 ug
16-0364Nucleosome, Recombinant Human, H3K23ac dNuc, Biotinylated50 ug
16-0365Nucleosome, Recombinant Human, H3K27ac dNuc Biotinylated20 ug
16-0365Nucleosome, Recombinant Human, H3K27ac dNuc Biotinylated50 ug
16-1365Nucleosome, Recombinant Human, H3K27ac dNuc, Non-biotinylated50 ug
16-0383Nucleosome, Recombinant Human, H3K27cr dNuc, Biotinylated50 ug
16-0338Nucleosome, Recombinant Human, H3K27me1 dNuc, Biotinylated50 ug
16-0339Nucleosome, Recombinant Human, H3K27me2 dNuc, Biotinylated50 ug
16-0317Nucleosome, Recombinant Human, H3K27me3 dNuc, Biotinylated20 ug
16-0317Nucleosome, Recombinant Human, H3K27me3 dNuc, Biotinylated50 ug
16-1317Nucleosome, Recombinant Human, H3K27me3 dNuc, Non-biotinylated50 ug
16-0378Nucleosome, Recombinant Human, H3K36ac dNuc, Biotinylated50 ug
16-0322Nucleosome, Recombinant Human, H3K36me1 dNuc, Biotinylated50 ug
16-0319Nucleosome, Recombinant Human, H3K36me2 dNuc, Biotinylated50 ug
16-0320Nucleosome, Recombinant Human, H3K36me3 dNuc, Biotinylated20 ug
16-0320Nucleosome, Recombinant Human, H3K36me3 dNuc, Biotinylated50 ug
16-1320Nucleosome, Recombinant Human, H3K36me3 dNuc, Non-biotinylated50 ug
16-0336Nucleosome, Recombinant Human, H3K4,9,14,18ac dNuc Biotinylated50 ug
16-0342Nucleosome, Recombinant Human, H3K4ac dNuc, Biotinylated50 ug
16-0321Nucleosome, Recombinant Human, H3K4me1 dNuc, Biotinylated20 ug
16-0321Nucleosome, Recombinant Human, H3K4me1 dNuc, Biotinylated50 ug
16-0334Nucleosome, Recombinant Human, H3K4me2 dNuc, Biotinylated20 ug
16-0334Nucleosome, Recombinant Human, H3K4me2 dNuc, Biotinylated50 ug
16-1334Nucleosome, Recombinant Human, H3K4me2 dNuc, Non-Biotinylated20 ug
16-1334Nucleosome, Recombinant Human, H3K4me2 dNuc, Non-Biotinylated50 ug
16-0316Nucleosome, Recombinant Human, H3K4me3 dNuc, Biotinylated20 ug
16-0316Nucleosome, Recombinant Human, H3K4me3 dNuc, Biotinylated50 ug
16-1316Nucleosome, Recombinant Human, H3K4me3 dNuc, Non-Biotinylated50 ug
16-0335Nucleosome, Recombinant Human, H3K4me3, K9,14,18ac dNuc, Biotinylated50 ug
16-0367Nucleosome, Recombinant Human, H3K79me1 dNuc, Biotinylated50 ug
16-0368Nucleosome, Recombinant Human, H3K79me2 dNuc, Biotinylated50 ug
16-0369Nucleosome, Recombinant Human, H3K79me3 dNuc, Biotinylated50 ug
16-0314Nucleosome, Recombinant Human, H3K9ac dNuc20 ug
16-0314Nucleosome, Recombinant Human, H3K9ac dNuc50 ug
16-1314Nucleosome, Recombinant Human, H3K9ac dNuc Non-Biotinylated50 ug
16-0371Nucleosome, Recombinant Human, H3K9bu dNuc, Biotinylated50 ug
16-0351Nucleosome, Recombinant Human, H3K9cr dNuc, Biotinylated50 ug
16-0325Nucleosome, Recombinant Human, H3K9me1 dNuc, Biotinylated50 ug
16-0324Nucleosome, Recombinant Human, H3K9me2 dNuc, Biotinylated20 ug
16-0324Nucleosome, Recombinant Human, H3K9me2 dNuc, Biotinylated50 ug
16-0315Nucleosome, Recombinant Human, H3K9me3 dNuc, Biotinylated20 ug
16-0315Nucleosome, Recombinant Human, H3K9me3 dNuc, Biotinylated50 ug
16-0382Nucleosome, Recombinant Human, H3R17me1 dNuc, Biotinylated50 ug
16-0375Nucleosome, Recombinant Human, H3R17me2a dNuc, Biotinylated50 ug
16-0340Nucleosome, Recombinant Human, H3R2me1 dNuc, Biotinylated50 ug
16-0341Nucleosome, Recombinant Human, H3R2me2a dNuc, Biotinylated50 ug
16-0355Nucleosome, Recombinant Human, H3R2me2s dNuc, Biotinylated50 ug
16-0379Nucleosome, Recombinant Human, H3R8me1 dNuc, Biotinylated50 ug
16-0380Nucleosome, Recombinant Human, H3R8me2a dNuc, Biotinylated50 ug
16-0381Nucleosome, Recombinant Human, H3R8me2s dNuc, Biotinylated50 ug
16-1345Nucleosome, Recombinant Human, H3S10ph dNuc, Non-biotinylated50 ug
16-0345Nucleosome, Recombinant Human, H3S10phos dNuc, Biotinylated50 ug
16-1313Nucleosome, Recombinant Human, H4 Tetraacetyl (H4K5,8,12,16ac) dNuc, Non-Biotinylated50 ug
16-0312Nucleosome, Recombinant Human, H4K12ac dNuc, Biotinylated50 ug
16-0393Nucleosome, Recombinant Human, H4K12me1 dNuc, Biotinylated50 ug
16-0354Nucleosome, Recombinant Human, H4K16ac dNuc, Biotinylated50 ug
16-0377Nucleosome, Recombinant Human, H4K20ac dNuc, Biotinylated50 ug
16-0331Nucleosome, Recombinant Human, H4K20me1 dNuc, Biotinylated50 ug
16-0332Nucleosome, Recombinant Human, H4K20me2 dNuc, Biotinylated50 ug
16-0333Nucleosome, Recombinant Human, H4K20me3 dNuc, Biotinylated50 ug
16-1333Nucleosome, Recombinant Human, H4K20me3 dNuc, Non-biotinylated50 ug
16-0352Nucleosome, Recombinant Human, H4K5ac dNuc50 ug
16-0353Nucleosome, Recombinant Human, H4K8ac dNuc, Biotinylated50 ug
16-0356Nucleosome, Recombinant Human, H4R3me1 dNuc, Biotinylated50 ug
16-0357Nucleosome, Recombinant Human, H4R3me2a dNuc, Biotinylated50 ug
16-0358Nucleosome, Recombinant Human, H4R3me2s dNuc, Biotinylated50 ug
16-0313Nucleosome, Recombinant Human, H4Tetraacetyl (H4K5,8,12,16ac) dNuc, Biotinylated50 ug
19-2100SNAP-ChIP OncoStat Panel200 ul