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 제품안내  면역학   Stem Cell

iPSC-derived Cells

역분화유도 줄기세포 (iPSC)로부터 유래된 Human Endothelial Cells, Human Cardiomyocytes, Human Neurons 을 소개합니다.

Axol
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특징

  • hiPSC-derived Renal Proximal Tubular Cells
        Albumin uptake assay에 의한 기능성 검증 완료
        -  OAT1, SGLT2, GGT 와 PEPT1같은 key markers를 발현
        -  해동 후 4일 후에 mature cells 얻을 수 있음.
            
Cat. No. Product name Donor_age Donor gender HLA_serotype Starting
material
Size
ax2115 Human iPSC-Derived Renal Proximal Tubular Cells (Male) Newborn Male A29 A68, B38(Bw4) B44(Bw4), Cw8 Cw12 Cord blood CD34+ cells ≥1 million cells


      Albumin endocytosis in iPSC-Derived Renal Proximal Tubular Cells
      
      
        100 ug/ml FITC-conjugated BSA 처리 후에 각 cell cytoplasm에 존재하는 것을 확인

  • hiPSC-derived Endothelial cells 

         - Human cells derived from healthy donors
           - Available in industrial quantity
           - High purity endothelial cell population
           - Ready-made and easy to culture
           - Expandable population

Cat. No. Product name Donor_age Donor gender HLA_serotype Starting
material
Size
ax2015  Human Endothelial Cells Newborn Male A29 A68, B38(Bw4) B44(Bw4), Cw8 Cw12 CD34+ cord blood 1M cells/vial
ax2515 Human Endothelial Cells Newborn Female A3 A33, B7(Bw6) B7(Bw6), Cw7 Cw7 CD34+ cord blood 1M cells/vial

 

  • hiPSC-derived Cardiomyocyte cells
    - Cardiac dysfunction (심부전) 및 cardiotoxicity (심근독성)등의 연구에 적합한 isogenic disease model을 제공하고 drug testing에도 사용할 수 있습니다.
    - Primary cell과 동등한 수준의 결과를 제공합니다.

    Cat. No. Product name Donor_age Donor gender HLA_serotype Starting
    material
    Size
    ax2505 Human Cardiomyocyte Cells - Male Newborn Male A29 A68, B38(Bw4) B44(Bw4), Cw8 Cw12 CD34+ cord blood 1,000,000 cells per vial


  • Human iPSC-Derived Retinal Pigment Epithelial Cells from a healthy male donor (ax0540) 

          - From healthy donor
          - 색소 침착, 다각형 형태를 가지며 polygonal 형태를 띄고, 멜라닌 소체를 함유
          - Key RPE marker인 tyrosinase, PMEL17, RPE65, RLLBP1과 BEST1를 발현함.
          - Phagocytosis를 관찰

      iPSC-Derived RPE cells incubated with pHrodo dye conjugates for 12 hours show phagocytosis of
      fluorescent BioParticles

         

        

  • Cell medium : Axol iPSC-derived cell culture에 필수적인 media 입니다.
    • Differentiation media : 세포 분화를 돕는 성분이 들어있는 media  
    • Expansion media : cell expansion 시 사용하는 media
    • Maintenance media : cell clumping 을 방지하여 장기간 배양 가능하게 해주는 media
    • Plating media : coating dish에 plating 할 때 사용하는 media

 

  • Reagents and Supplements
    • Axol Sure Bond : Culture dish를 코팅시켜서 배양 중 세포가 dish로 부터 잘 떨어지도록 도와줍니다.
    • Axol Unlock : Axol Sure Bond와 함께 사용하는 buffer solution 입니다.
    • Axol Sure Growth : Progenitor cell의 proliferation을 촉진시켜줍니다.
    • Axol Sure Mix : Cell clupming을 방지하여 cell culture passage를 증가시켜줍니다.
    • Axol Sure Boost : Neural cell의 viability를 증가시켜줍니다.
    • Axol Neural Enhance & Advance : Neural progenitor cell의 분화를 도와줍니다.
    • Axol ReadyFect : Neural progenitor cell에 특화되어 있는 lipid-based transfection reagent 입니다. 

주문정보(Ordering Information)
CATNUM PRODUCT SIZE
ax0111Alzheimer's Disease Neural Stem Cells (APOE4)ea
ax0114Alzheimer's Disease Neural Stem Cells (PSEN-1 A246E)ea
ax0112Alzheimer's Disease Neural Stem Cells (PSEN-1 L286V)ea
ax0113Alzheimer's Disease Neural Stem Cells (PSEN-1 M146L)ea
ax0115Alzheimer's Disease Neural Stem Cells (PSEN-2 N141I)ea
ax2530-500Axol iPSC Cardiomyocyte Maintenance Medium Kitea
ax0311axolGEM iPSC-Derived Neural Stem Cells LKKR2 G2019S HETea
ax0310axolGEM iPSC-Derived Neural Stem Cells LKKR2 G2019S HOMea
ax0325axolGEM iPSC-Derived Neural Stem Cells MAPT P301L HETea
ax0324axolGEM iPSC-Derived Neural Stem Cells MAPT P301L HOMea
ax0321axolGEM iPSC-Derived Neural Stem Cells MAPT R406W HETea
ax0320axolGEM iPSC-Derived Neural Stem Cells MAPT R406W HOMea
ax0323axolGEM iPSC-Derived Neural Stem Cells MAPT V337M HETea
ax0322axolGEM iPSC-Derived Neural Stem Cells MAPT V337M HOMea
ax0026Cerebral Cortical Neurons (Female) - plated format (7-10 days)ea
ax0029Cerebral Cortical Neurons (Female) - plated format (7-10 days)ea
ax0025Cerebral Cortical Neurons (Male) - plated format (7-10 days)ea
ax0028Cerebral Cortical Neurons (Male) - plated format (7-10 days)ea
ax0026FCortical Neuron Differentiation kit (Female)ea
ax0029FCortical Neuron Differentiation kit (Female) ea
ax0025FCortical Neuron Differentiation kit (Male)ea
ax0028FCortical Neuron Differentiation kit (Male)ea
ax0411Epilepsy Neural Stem Cellsea
ax2019Human Endothelial Cells - female donorea
ax2015Human Endothelial Cells - male donorea
ax2515Human iPSC-derived Atrial Cardiomyocytes ea
ax2505Human iPSC-derived Ventricular Cardiomyocytes - male donorea
ax0212Huntington's Disease Neural Stem Cells (male, CAG:56)ea
ax0100iPSC-derived Neural Stem Cell Kitea
ax0034-125Neural Differentiation-XF Mediumea
ax0030-500Neural Expansion-XF Mediumea
ax0031Neural Maintenance Medium Kitea
ax0032-500Neural Maintenance-XF Mediumea
ax0016Neural Stem Cells (Female)ea
ax0019Neural Stem Cells (Female) ea
ax0015Neural Stem Cells (Male) ea
ax0018Neural Stem Cells (Male) ea
ax1001Neural Stem Cells (Trisomy X Mutation)ea
ax0033Plating-XF Mediumea
ax0051ReadyFectea
ax0045Sure Boostea
ax0047Sure Growth, Recombinant Human FGF2 ea
ax0047XSure GrowthX, Recombinant Human EGFea
ax0041SureBond ea
ax0041+SureBond+ReadySetea
ax0041XFSureBond-XFea
ax0043SureMixea
ax0044Unlockea
ax0044XFUnlock-XFea