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 제품안내  실험기기   신경신호 탐색 장비

Neurophysiology Data Acquisition System

동물의 뇌, 신경자극을 기록, 분석하는 Data Acquisition System 및 Multi-Channel의 대명사인 Utah array를 소개합니다.

Blackrock Microsystems
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특징



 
                                         Neurosignal을 저장하는 데이터 수집 장치


Cerebus System
• Extendable to 1024 channels (16-bit@30 kHz)
• Real-time processor & operating system
• Extension firmware
• Extensive digital/analog I/O
• User-friendly software & C++/Matlab SDK
• Works w/ all Blackrock headstages
• Hardware Line Noise Cancellation



CerePlex Direct System
• Compact design
• Easy to use
• Adequate D/A input
• Fully functional software
• C++/Matlab SDK
• Sync w/ video tracking system
• Compatible w/ all digital headstages          


                                 노이즈가 없고 작고 가벼운 digital headstage

CerePlex M
• Ideal for Rodent work
• Onboard digitization
• Multiplexed, 7-wire output for 32, 64, or 96 electrodes
• Eliminates artifacts from cable motion and environmental noise
• Spike and field potential recording

CerePlex E
• Ideal for large animals
• On-board digitizing amplifier
• 7-wire output for 128 electrodes
• Eliminates artifacts from cable motion and environmental noise
• Ultra-wideband recording
• Real-time, stimulus-artifact suppression

CerePlex A
• Neural Signal Inputs  : 128
• Input Connectors (bank  A-D) : QSE, dual row, 40 pins, male
• Input Connectors (GND, X REF)  : 1.5mm touch proof, male
• Input Range  : ± 8 mV
• A-D Conversion  : 30 kHz, 16 bits (0.25 μV/bit resolution)
• Input-Referred Noise : 3 μVrms

CerePlex Mu
• 무게 1g 초소형으로 mouse의 움직임에 부담을 주지 않습니다.
• 매우 얇고 가벼운 전용 cable과 함께 이용합니다.
• 자체 개발된 Full Digital Blackrock Chip을 이용합니다.
• ENOB : 16 bit
• Built-in 3D motion sensing
• Built-in color or IR LED for tracking
• In-vivo impedance measurement
• Stimulation과 Recording을 동시에!
• Number of channels: 16 or 32
• Input connector: Omnetics (custom versions coming soon)
• Blackrock system : Digital data acquisition device (Cerebusor CerePlexDirect)
• Compatible array : Utah Array (Omneticsconnector), Laminar Probe
• Power requirements : +5/-3 VDC
• Sampling : 30 kHz at 16 bits
• Mode of operation : Continuous
• Input frequency range : 0.3 Hz –7.5 kHz
• Input impedance : 1300 MΩ@ 10 Hz, 13 MΩ@ 1 kHz
• Maximum input range : ±5 mV with respect to reference
• Resolution : 16-bit ADC, 195 nV/bit        

CerePlex W
•작고 가벼운 무선 digital headstage
•Large animal freely behaving 연구에 적합
•Very small size
•Light weight
•Long battery life
•Freely moving recording with multiple animals
•Full bandwidth 30 kS/s sampling
•96 channels
•All digital recording and transmission
                            


                               신경 부위에 임플란트되는 electrode 및 inserter

Utah Array
•다채널로부터의 신경 기록을 한번에 수집할 수 있습니다.
• 최대 128개의 전극을 갖는 형태로 제작할 수 있습니다.
• 이식 후 바로 고퀄리티 신경기록을 얻을 수 있습니다.
• 멸균 가능합니다. (임상용)
• acute, chronic 모두에 안정적으로 사용 가능합니다. 
• 여러 connector option을 제공합니다. (omnetics, samtec, cereport)
• Motor & Sensory cortex, Spinal cord, Peripheral nerve fibers 리코딩과 stimulation에 효과적입니다. 
• 전극 수, 깊이, 재질, wire 길이등을 원하시는 대로 커스터마이징 할 수 있습니다.
• 경사가 있는 형태로도 제작 가능합니다.
• Human, primate 연구에 특히 유용합니다.     



Microelectrode array inserter
•High-speed pneumatic insertion
•Adjustable implantation depth
•Minimal tissue insult
•In-vivo or in-vitro preparations
•Sterilizable
                                        


           

 
                                          신경에 자극을 공급하는 장치





CereStim R96
• 최대 96채널까지 전기자극
• 한번에 1개, 3개, 혹은 16개 채널 자극
• 자극에서 기록까지 신속한 전달 (Spike 1ms, LFP 5ms)
• Micro current range : 0.001 – 0.215mA
• Macro currnet range: 0.1 – 10mA 
                                             

                                                               



Optogenetics Starter Kit
•Allows researchers to combine optogenetic
neural stimulation recording and stimulation
with simultaneous microelectrode recording
•The DC2100 can operate in Constant Current Mode,
Pulse-Width Modulation Mode (PWM) or External
Control Mode, which enables control by Blackrock’s neural signal processor
•Multiple modes provide research flexibility
depending on subject
•Software can be controlled remotely via a
Windows-based PC

                                        신경 신호를 분석하는 소프트웨어



BOSS Analysis Software
•Intuitive and user friendly
•Wizard-assisted sorting and extraction
•Fully customizable user interface
•Multi-platform (OS X, Windows, Linux)
•Automatically saves file editing sessions for easy data analysis continuation after interruptions
•Background thread for detection and sorting keeps user interface performance uncompromised
•Background organization of data increases processing speed
•Large file support
•Manual and automated sorting algorithms including T-Distribution EM, K-Means and Manual Editing
•Automatic estimation of most relevant feature spaces for faster and more accurate sorting
•Allows saving and loading detection and sorting parameters to easily set up the environment for similar experiments across files

System requirement
•OS : Mac OS10, Windows® 7
•CPU : ≥ 4 physical cores at 2GHz
•RAM : 4 GB
•Hard drive : 1TB 3Gbit/s SATA II HDD
•Display : Video card with full OpenGL compatibility                                             



NeuroExplorer Analysis Software
•Imports data files natively
•Accommodates all standard histogram and raster analyses
•Shift predictors in cross-correlograms and color markers in perievent rasters
•Joint PSTH, burst analysis and many more analyses of time-stamped data
•Spectral analysis of spike and continuous data
•3D data view and animation
•Fully customizable WYSIWYG graphics
•Custom analysis and batch-mode processing with internal scripting language
•Direct data link to Matlab and Excel
•Statistical tests via direct link to R-project            

System requirement
•Windows® XP, Vista, 7 or 8 and Windows® Server 2003, 2008 or 2012 (32-bit or 64-bit). Works on Mac under Parallels.
•Minimum 256 MB RAM (4 GB recommended)
•1024 × 768 minimum video resolution
•30 MB of disk space
•USB port                               





       

  



                                              행동 추적 시스템

NeuroMotive Video Capturing System
•Multi-marker tracking in light or dark environments
•Trigger outputs based on animal location
•Synchronized neural recordings
•Input of annotations and user-defined events
•DVD-like playback

Specifications
•Maximum resolution : 1,600 (H) x 1,200 (V)
•Maximum frame rate : 100 Hz
•Lens mount : C
•Video file formats : AVI, MJPEG
•Lighting : Visible and infrared
•Tracking distance : Minimum: 2 ft. (0.6 m); Maximum: 20 ft. (6.1 m)
•API type : C/C++ DLL


Virtual Reality (VR) JetBall    
•Easy construction of virtual mazes via software that can replicate most classical mazes
•Placing of landmarks of various sizes and shapes that appear or disappear at predefined times
•Combination of virtual reality with acoustic, olfactory and tactile stimuli
•Export of time stamp, position and speed via an external interface for synchronization with other data types
•Appropriate for all kinds of ephys setups and most multi-photon microscopes
•Easy interfacing with electrophysiology setups
•Retractable operant device for reinforcement: positive (water) and negative (air puff)
•Common mazes or customized virtual reality scenes                
                       

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