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 Á¦Ç°¾È³»  Çü±¤½Ã¾à   Protein Labeling  CF¢â Dyes

In Vivo Imaging¿ë CF Dye

in vivo imaging¿¡ ÀÌ¿ëµÇ´Â Near-infrared CF dye¸¦ ¼Ò°³ÇÕ´Ï´Ù.

Biotium
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  • Annexin V´Â 35-36kDa ´Ü¹éÁú·Î, apoptosis°¡ ÀϾ´Â °æ¿ì cell membraneÀÇ cytoplasmic surfice¿¡ Á¸ÀçÇÏ´Â phosphatidylserine (PS)ÀÌ ¹Ù±ùÂÊÀ¸·Î ³ëÃâµÇ¸é ¿©±â¿¡ bindingÇÕ´Ï´Ù.
  • Near-IR CF Dye Annexin V´Â azideµîÀÇ toxic ¼ººÐÀ» Æ÷ÇÔÇÏÁö ¾Ê¾Æ in vivo imaging¿¡µµ »ç¿ë °¡´ÉÇÕ´Ï´Ù.
  • Çü±¤Çö¹Ì°æ, live cell imaging, flow cytometry¿¡ »ç¿ëÇÒ ¼ö ÀÖ½À´Ï´Ù.
  • 7°¡Áö Near-IR CF Dye Ä÷¯°¡ Á¦°øµË´Ï´Ù.



  • Non-reactive, free acid formÀÇ Near-infrared (NIR) CF dye·Î, NIR CF® dye conjugatesÀÇ reference standard³ª control·Î ÀÌ¿ëµÉ ¼ö ÀÖ½À´Ï´Ù.
  • in vitro cell based assay¿¡ »ç¿ëµÉ °æ¿ì¿¡´Â dye-labeled agentÀÇ bindingÀ» ¸ð´ÏÅ͸µÇϰųª in vivo·Î Åõ¿©µÇ´Â agent¸¦ °¡½ÃÈ­ Çϴµ¥ È¿°úÀûÀÔ´Ï´Ù.
  • in vivo·Î »ç¿ëµÉ °æ¿ì¿¡´Â animal body¿¡¼­ÀÇ dye kinetics¸¦ °üÂûÇϴµ¥ À¯¿ëÇÕ´Ï´Ù.
  • 4°¡Áö CF Dye Ä÷¯°¡ Á¦°øµË´Ï´Ù. : CF®680, CF®750, CF®770, CF®790




  • Small animal in vivo imagingÀ» À§ÇØ antibody¿¡ Çü±¤À» ¶óº§¸µÇϰí Á¤Á¦Çϴ ŶƮÀÔ´Ï´Ù.
  • Near-infrared amine-reactive CF dye¸¦ ¿øÇϽô Ç×ü¿¡ ¼Õ½±°Ô ¶óº§¸µÇÒ ¼ö ÀÖ½À´Ï´Ù.
  • ŶƮÀÇ ±¸¼º
    • Lyophilized Near-IR CF® Dye SE (3 vials)
    • Anhydrous DMSO
    • Sodium Bicarbonate Solution, pH 8.3
    • 1X PBS, pH 7.4
    • Ultrafiltration Vials, 10K MWCO (3 vials)
    • Reaction Vials (3 vials)
    • Sterile Storage Vials (3 vials)
    • 1 mL Syringes (3 syringes)
    • 0.2 um, 4 mm Sterile Syringe Filters (3 filters)



  • DiR (DiIC18(7); 1,1′-dioctadecyl-3,3,3′,3′-tetramethylindotricarbocyanine iodide)´Â lipophilic, near-infrared fluorescent cyanine dye ÀÔ´Ï´Ù.
  • cytoplasmic membrane ¶óº§¸µ¿¡ È¿°úÀûÀÔ´Ï´Ù.
  • near-infrared in vivo imaging¿¡ »ç¿ëµË´Ï´Ù.
  • 2°³ÀÇ 18-carbon chainÀÌ cell membrane¿¡ »ðÀԵǾî, cell°£ÀÇ dye transfer ¾øÀÌ specific & stable cell stainingÀ» À¯µµÇÕ´Ï´Ù.