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 제품안내  면역학   Neuroscience  Ion Channel

Calcium(Ca2+) Channel Products

세포내 활성-불활성에 관여하는 중요한 messenger ion중의 하나인 Calcium(Ca2+) Channel에 대한 항체와 agonist & antagonist를 소개합니다.

TOCRIS
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특징
신경세포에서 Calcium channel은 voltage-dependant Ca2+ influx를 매개하여 synaptic response를 통해 gene expression 조절및 synaptic transmission을 개시합니다. 이 채널은 class A,B,C,D,E로 구분되며, neuromuscular disease에 중요한 역할을 합니다.
적용
Immunohistochemical staining of Cav2.1 channel with Anti-Cav2.1 antibody (#ACC-001) (1:100) in mouse cerebellum. (A) Cav2.1 channel (red) appears in Purkinje cells (horizontal arrows) and is distributed diffusely in the molecular layer (Mol) including in astrocytic fibers (vertical arrows). (B) staining of astrocytic fibers with glial fibrillary acidic protein in the section demonstrates the location of astrocytic fibers in the molecular layer. (C) Confocal merge of Cav2.1 and GFAP.
Immunohistochemical staining of Cav1.2a in rat heart using Alomone rabbit Anti-Cav1.2a (#ACC-013). Cav1.2a was visualized with immuno-peroxidase methods and final brown-black diaminobenzidine color product (arrows in A). The counterstain is cresyl violet. When the antibody was pre-incubated with the immunogen, staining was blocked (B).
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1544((±)-Bay K 8644 Agonists & Antagonists
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1124(R)-(-)-Niguldipine hydrochloride Agonists & Antagonists
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1123(S)-(+)-Niguldipine hydrochloride Agonists & Antagonists
1123(S)-(+)-Niguldipine hydrochloride Agonists & Antagonists
1546(S)-(-)-Bay K 8644 Agonists & Antagonists
1546(S)-(-)-Bay K 8644 Agonists & Antagonists
59001A-23187 Free Acid (calcimycin; or Calcium Ionophore III)Indicator
ACC-003-AGAnti-Cav1.2-ATTO-488Antibody
C-650CalcicludineAgonists & Antagonists
C-500CalciseptineAgonists & Antagonists
0685Diltiazem hydrochloride Agonists & Antagonists
59002EDC (EDAC; 1-(3-dimethylaminopropyl-3-ethylcarbodiimide, hydrochloride))Indicator
50013Fluo-3, AM esterIndicator
1403FPL 64176 Agonists & Antagonists
1403FPL 64176 Agonists & Antagonists
F-700FS-2Agonists & Antagonists
50033Fura-2, AM ester (special packaging)Indicator
50037Furaptra, AM ester (also known as Mag-Fura-2, AM ester) (special packaging)Indicator
0806Gabapentin Agonists & Antagonists
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50043Indo-1, AM ester (special packaging)Indicator
2004Isradipine Agonists & Antagonists
2004Isradipine Agonists & Antagonists
0840Loperamide hydrochloride Agonists & Antagonists
C-670mc-Conotoxin MVIIAAgonists & Antagonists
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1075Nifedipine Agonists & Antagonists
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2268NNC 55-0396 dihydrochloride Agonists & Antagonists
A-500omega-Agatoxin IVAAgonists & Antagonists
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C-150omega-Conotoxin MVIICAgonists & Antagonists
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59000Pluronic F-127Indicator
50023Rhod-2, AM ester (special packaging)Indicator
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