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 제품안내  면역학   Cell Signaling  GPCR Product

ChemiScreen GPCR Cell Lines

Calcium-based functional screening을 위한 ChemiScreen GPCR cell lines을 소개합니다.

Eurofins
제품 문의하기
인쇄하기

    특징
  • 세포 표면에 수용체의 functional expression이 뛰어납니다.
  • G Protein과 결합한 상태에서도 Ca2+ signaling이 원활히 진행됩니다.
  • 세포 특징의 정확성과 배치간의 재현성이 우수한 안정된 세포주 입니다.
  • Functional readout이 단순합니다.
  • Cell-based screening and profiling을 이용한 drug discovery에 사용될 수 있습니다.
  • 150여가지의 Ca2+-optimized cell line이 있습니다.
    적용

    Figure 1. ChemiScreen Cell Lines Funnel All GPCR Signaling Through a Common Functional Readout.

    (A) Using native Gα coupling hampers drug discovery efforts because of the need to develop multiple assays. (B) Millipore's unique and common readout for all targets simplifies assay conditions and standardizes buffer conditions and incubation times, which results in easy data comparison.

    Figure 2. ChemiScreen GPCR surface expression

    Higher level surface expression of recombinant GPCR using Millipore's proprietary mammalian expression system, (A)CXCR2-GFP/pcDNA3 in Chem-1 cells; (B) CXCR2-GFP/pHS (Millipore's proprietary expression vector) in Chem-1 cells.
주문정보(Ordering Information)
CATNUM GPCR Family/GPCR Target/Ligand Type Host Cell
HTS213C1321N1-P2Y11 Calcium Cell Line
HTS107C5-HT1A Calcium Cell Line
HTS082C5-HT2A CA CELL LINE
HTS109C5-HT2B Calcium Cell Line
HTS132C5-HT2C Calcium Cell Line
HTS110C5-HT4B Calcium Cell Line
HTS111C5-HT6 Calcium Cell Line
HTS047CA1 CA CELL LINES
HTS051CA2B CA CELL LINES
HTS052CA3 CA CELL LINES
HTS087Calpha1A CA CELL LINE
HTS096Calpha2A Calcium Cell Line
HTS068CAPJ CA CELL LINE
HTS064CAT1 CA CELL LINE
HTS041CB2 CA CELL LINES
HTS123CBB1 Calcium Cell Line
HTS084CBB2 CA CELL LINE
HTS160CBB3 Calcium Cell Line
HTS104CBeta 1 Calcium Cell Line
HTS073CBETA2 CA CELL LINE
HTS159CBeta3 Calcium Cell Line
HTS042CBLT1 CA CELL LINES
HTS016CC3AR CA CELL LINES
HTS017CC5AR CA CELL LINES
HTS137CCaS Calcium Cell Line
HTS019CCB1 CA CELL LINES
HTS020CCB2 CA CELL LINES
HTS083CCCK CA CELL LINE
HTS184CCCK1 Calcium Cell Line
HTS005CCCR1 CA CELL LINES
HTS014CCCR10 CA CELL LINES
HTS006CCCR2A CA CELL LINES
HTS007CCCR2B C CA CELL LINES
HTS008CCCR3 CA CELL LINES
HTS009CCCR4 CA CELL LINES
HTS010CCCR5-Rhesus Calcium Cell Line
HTS011CCCR6 CA CELL LINES
HTS012CCCR7 CA CELL LINES
HTS013CCCR8 CA CELL LINES
HTS036CCCR9 CA CELL LINES
HTS172CCGRP1 Calcium Cell Line
HTSCHEM-1CHEM-1 PARENT CELL LNE 2VLS 1X10(6) EA
HTSCHEM-2CHEM-2 PARENT CELL LNE 2VLS 1X10(6) EA
HTSCHEM-3CHEM-3 PARENT CELL LNE 2VLS 1X10(6) EA
HTS053CChem-4-XCR1 Calcium Cell Line
HTS158CChem1-Alpha1B Calcium Cell Line
HTS216CChem1-Alpha1D Calcium Cell Line
HTS206CChem1-MrgD Calcium Cell Line
HTS198CChem10-GPR119 Calcium Cell Line
HTS155CChem10-MC5 Calcium Cell Line
HTS133CChem10-TSHR Calcium Cell Line
HTS201CChem4-GPR109A Calcium Cell Line
HTS180CChem4-NPBW1 Calcium Cell Line
HTS192CChem5-S1P4 Stable Cell Line
HTS048LChemiBrite™ A2A Adenosine Receptor
HTS157LChemiBrite™ alpha2b Stable Cell Line
HTSCH0-1LChemiBrite™ CHO Parental Cell Line
HTS003LChemiBrite™ CXCR3 Chemokine Recepto
HTS061LChemiBrite™ CysLT1 Stable Cell Line
HTS091LChemiBrite™ DP Prostanoid Receptor
HTS099LChemiBrite™ EP1 Prostanoid Receptor
HTS185LChemiBrite™ EP2 Prostanoid Receptor
HTS092LChemiBrite™ EP3 Prostanoid Receptor
HTS142LChemiBrite™ EP4 Stable Cell Line
HTS038LChemiBrite™ FFA1/GPR40 Stable Cell Line
HTS093LChemiBrite™ FP Prostanoid Receptor
HTS178LChemiBrite™ FSH Stable Cell Line
HTS163LChemiBrite™ GLP-1 Glucagon Family Recept
HTS238LChemiBrite™ GPBA Bile Acid Receptor
HTS198LChemiBrite™ GPR119 Receptor Stable
HTS225LChemiBrite™ GPR120 Receptor Stable
HTSHEK-4LChemiBrite™ HEK293 Parental Cell Li
HTSHEK-1LChemiBrite™ HEK293 Parental Cell Line
HTSHEK-5LChemiBrite™ HEK293 Parental Stable
HTSHEK-6LChemiBrite™ HEK293 Parental Stable
HTSHEK-3LChemiBrite™ HEK293 Parental Stable Cell Line with Gαqi
HTSHEK-2LChemiBrite™ HEK293 Parental Stable Cell Line with Gαqs
HTS131LChemiBrite™ IP1 Prostanoid Receptor
HTS233LChemiBrite™ LH Stable Cell Line
HTS049LChemiBrite™ P2Y1 Stable Cell Line
HTS213LChemiBrite™ P2Y11 Stable Cell Line
HTS195LChemiBrite™ P2Y12 Stable Cell Line
HTS210LChemiBrite™ P2Y2 Stable Cell Line
HTS211LChemiBrite™ P2Y4 Stable Cell Line
HTS081LChemiBrite™ TP Stable Cell Line
HTSU20S-1LChemiBrite™ U2OS Parental Cell Line
HTS138C2ChemiScreen CXCR7 Chemokine Cell Line
HTS235CChemiScreen™ alpha2C Stable Cell Line
HTS163C2ChemiScreen™ GLP-1 Stable CHO Cell Line
HTS241CChemiScreen™ GPR91 Stable Cell Line
HTS207CChemiScreen™ LPA2 Lysophospholipid Famil
HTS156CChemiScreen™ MC1 Stable Cell Line
HTS071CCHEMR23 CA CELL LINE
HTS023CCRF1 CA CELL LINES
HTS024CCRF2 CA CELL LINES
HTS015CCX3CR1 CA CELL LINES
HTS001CCXCR1 CA CELL LINES
HTS002CCXCR2 CA CELL LINES
HTS003CCXCR3 CA CELL LINES
HTS004CCXCR4 CA CELL LINES
HTS055CCXCR5 Calcium Cell Line
HTS054CCXCR6 CA CELL LINES
HTS061CCysLT1 CA CELL LINE
HTS088CCysLT2 CA CELL LINE
HTS102CD1 Calcium Cell Line
HTS039CD2 Calcium Cell Line
HTS039C2D2L cAMP Cell Line
HTS223CD4 Calcium Cell Line
HTS129CD5 Calcium Cell Line
HTS100CDelta Calcium Cell Line
HTS091CDP CA CELL LINE
HTS099CEP1 Calcium Cell Line
HTS185CEP2 Calcium Cell Line
HTS092CEP3 CA CELL LINE
HTS142CEP4 Calcium Cell Line
HTS070CETA CA CELL LINE
HTS046CETB Calcium Cell Line
HTS093CFP Calcium Cell Line
HTS018CFPR1 CA CELL LINE
HTS056CFPRL1 CA CELL LINES
HTS119CGABA-B1b Calcium Cell Line
HTS094CGAL1 Calcium Cell Line
HTS186CGAL2 Calcium Cell Line
HTS187CGhrelin Receptor Calcium Cell Line
HTS134CGIP Calcium Cell Line
HTS163CGLP-1 Calcium Cell Line
HTS164CGLP-2 Receptor Calcium Cell Line
HTS112CGlucagon Receptor CA Cell Line
HTS027CGNHR CA CELL LINES
HTS189CGPR103 Calcium Cell Line
HTS033CGPR14 CA CELL LINES
HTS217CGPR39 Calcium Cell Line
HTS135CGPR41 Calcium Cell Line
HTS063CGPR43 CA CELL LINE
HTS032CGPR54 CA CELL LINES
HTS153CGPR68 Stable Cell Line
HTS209CGPR92 Calcium Stable Cell Line
HTS191CGPR99 Calcium Cell Line
HTS050CH1 CA CELL LINES
HTS086CH2 Calcium Cell Line
HTS029CH3 CA CELL LINES
HTS131CIP1 Chem1 Stable Cell Line
HTS095CKappa Calcium Cell Line
HTS089CLPA1 Calcium Cell Line
HTS130CLPA3 Calcium Cell Line
HTS044CM1 CA CELL LINES
HTS115CM2 Calcium Cell Line
HTS116CM3 Calcium Cell Line
HTS117CM4 Calcium Cell Line
HTS075CM5 CA CELL LINE
HTS021CMC2 CA CELL LINES
HTS105CMC4 Calcium Cell Line
HTS025CMCHR1 CA CELL LINES
HTS026CMCHR2 CA CELL LINES
HTS145CmGlu1 Calcium Cell Line
HTS146CmGlu2 Calcium Cell Line
HTS121CMotilin Receptor Calcium Cell Line
HTS122CMrgX1 Calcium Cell Line
HTS058CMRGX2 CA CELL LINES
HTS101CMu Stable Cell Line
HTS080CNK1 CA CELL LINE
HTS144CNK2 Calcium Cell Line
HTS190CNK3 Stable Cell Line
HTS062CNMU1 CA CELL LINE
HTS098CNMU2 stable cell line
HTS040CNOP/ORL1 CA CELL LINES
HTS188CNPSR Calcium Cell Line
HTS034CNTR1 CA CELL LINES
HTS090COT Calcium Cell Line
HTS175COX1 Calcium Cell Line
HTS045COX2 Calcium Cell Line
HTS049CP2Y1 CA CELL LINES
HTS195CP2Y12 Calcium Cell Line
HTS210CP2Y2 1321N1 Calcium Cell Line
HTS211CP2Y4 1321N1 Calcium Cell Line
HTS114CPAC1-long Calcium Cell Line
HTS076CPAF CA CELL LINE
HTS037CPAR-2 CA CELL LINES
HTS074CPK1 CA CELL LINE
HTS182CPK2 Chem-1 Stable Cell Line
HTS057CPRP CA CELL LINES
HTS030CPTH CA CELL LINES
HTS173CPTH2 Calcium Cell Line
HTS176CS1P1 stable cell line
HTS078CS1P2 CA CELL LINE
HTS097CS1P3 Calcium Cell Line
HTS193CS1P5 Chem5 Calcium Cell Line
HTS174CSecretin Receptor Calcium Cell Line
HTS171CSST3 Calcium Cell Line
HTS125CSST4 Calcium Cell Line
HTS139CSST5 Chem1 Stable Cell Line
HTS028CSSTR2 CA CELL LINES
HTS081CTP CA CELL LINE
HTS126CTRH Calcium Cell Line
HTS059CV1A CA CELL LINES
HTS177CV1a Rat Chem-1 Stable Cell Line
HTS136CV1b Calcium Cell Line
HTS060CVASSOPRESSIN V2 CA CELL LINES
HTS043CVPAC1 CA CELL LINES
HTS079CVPAC2 CA CELL LINE
HTSCHEM-10Wild-type Chem-10 Cell Line
HTSCHEM-5Wild-Type Chem-5 Cell Line
HTSCHEM-9Wild-type Chem-9 Cell Line
HTS066CY2 CA CELL LINE
HTS204CY4 Calcium Cell Line