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 제품안내  신경약학   Cell Biology

DNA/RNA/Protein Synthesis Inhibitors

DNA, RNA, Protein 합성과정에 관여하는 inhibitor 를 소개합니다.

TOCRIS
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　 Cat. No. Product Name / Activity
　 4215 4E1RCat
　 　 Protein translation inhibitor; blocks eIF4F subunit interaction
　 4800 4EGI-1
　 　 Inhibitor of eIF4E:eIF4G interaction
　 1229 Actinomycin D
　 　 RNA polymerase inhibitor
　 2513 Acyclovir
　 　 Viral DNA polymerase inhibitor
　 4025 α-Amanitin
　 　 Inhibitor of RNA polymerase II
　 1290 Anisomycin
　 　 Protein synthesis inhibitor
　 5736 Aphidicolin
　 　 DNA polymerase α, δ and ε inhibitor
　 6392 B02
　 　 RAD51 recombinase inhibitor
　 2981 BIBR 1532
　 　 Selective telomerase inhibitor
　 5417 BMH 21
　 　 RNA polymerase 1 inhibitor; also p53 pathway activator
　 5312 BRACO 19 trihydrochloride
　 　 Telomerase inhibitor
　 6196 Brequinar sodium
　 　 Potent and selective DHODH inhibitor
　 4799 Capecitabine
　 　 Prodrug of 5-Fluorouracil (Cat. No. 3257). Inhibits DNA synthesis
　 2626 Carboplatin
　 　 Inhibitor of DNA synthesis
　 4436 8-Chloroadenosine
　 　 Cytotoxic nucleoside analog; inhibits RNA synthesis
　 2294 Cordycepin
　 　 RNA synthesis inhibitor
　 2483 Costunolide
　 　 Inhibitor of human telomerase activity
　 970 Cycloheximide
　 　 Inhibitor of protein synthesis
　 4520 Cytarabine
　 　 Nucleoside analog; inhibits DNA replication
　 3917 Daptomycin
　 　 Antibiotic; inhibits protein, DNA and RNA synthesis in gram-positive bacteria
　 1467 Daunorubicin hydrochloride
　 　 RNA synthesis inhibitor
　 3857 Dexrazoxane hydrochloride
　 　 Topoisomerase II inhibitor
　 3260 Epirubicin hydrochloride
　 　 Inhibits DNA synthesis and function. Inhibits DNA topoisomerase II
　 4659 Floxuridine
　 　 Disrupts DNA replication; inhibits thymidylate synthetase
　 3495 Fludarabine
　 　 Purine analog; inhibits DNA synthesis
　 3257 5-Fluorouracil
　 　 Inhibits RNA and DNA synthesis
　 4131 G418 disulfate salt
　 　 Aminoglycoside antibiotic; used in cell culture
　 3259 Gemcitabine hydrochloride
　 　 DNA synthesis inhibitor
　 1993 Halofuginone hydrobromide
　 　 High affinity competitive prolyl-tRNA synthetase inhibitor
　 1416 Homoharringtonine
　 　 Inhibitor of protein synthesis; antileukemic agent
　 5740 6-Hydroxy-DL-DOPA
　 　 Allosteric inhibitor of RAD52; also APE1 inhibitor
　 6483 Isoginkgetin
　 　 Pre-mRNA splicing inhibitor; cell permeable
　 7338 K 22 
　 　 Inhibits coronavirus RNA replication; impairs double membrane vesicle (DMV) formation
　 6068 Lin28 1632
　 　 RNA binding protein Lin28 inhibitor; promotes mESC differentiation; also bromodomain inhibitor
　 3765 Linezolid
　 　 Antibiotic; inhibits protein synthesis in gram-positive bacteria
　 6510 LNT 1
　 　 Potent flap endonuclease 1 (FEN1) inhibitor; induces DNA damage response
　 6819 Mefloquine hydrochloride
　 　 Binds 80S ribosome and inhibits protein synthesis in P falciparum; also gap junction blocker
　 4103 6-Mercaptopurine
　 　 Purine analog; inhibits DNA and RNA synthesis
　 1489 Mithramycin A
　 　 Inhibitor of DNA and RNA polymerase
　 3258 Mitomycin C
　 　 Inhibitor of DNA synthesis
　 6359 Nelarabine
　 　 Purine nuceloside analog; inhibits DNA synthesis
　 5340 NSC 617145
　 　 Werner syndrome helicase (WRN) inhibitor
　 2623 Oxaliplatin
　 　 Inhibitor of DNA synthesis
　 5419 PCNA I1
　 　 PCNA inhibitor
　 6222 PFM 01
　 　 MRE11 endonuclease inhibitor
　 6070 Pladienolide B
　 　 mRNA splicing inhibitor; antitumor
　 4089 Puromycin dihydrochloride
　 　 Protein synthesis inhibitor
　 6168 RI 1
　 　 RAD51 recombinase inhibitor
　 4501 Ribavirin
　 　 Antiviral guanosine analog; blocks eIF4E activity
　 4121 Rifampicin
　 　 Antibiotic; inhibits bacterial RNA polymerase
　 4723 T2AA
　 　 PCNA inhibitor
　 6884 TC SL C5
　 　 Metastasis-associated lung adenocarcinoma transcript 1 (Malat1) RNA inhibitor
　 5069 Teriflunomide
　 　 Inhibitor of DHODH; active metabolite of Leflunomide
　 3267 Thiostrepton
　 　 Antibiotic, inhibits protein synthesis
　 4309 TPEN
　 　 RNA binding protein Lin28 inhibitor; cell-permeable Zn2+ chelator
　 3253 Triptolide
　 　 Inhibits RNAPII-mediated transcription; antitumor, anti-inflammatory and immunosuppressive
　 3863 Trovafloxacin mesylate
　 　 Antibiotic; inhibits bacterial DNA synthesis
　 3787 Viomycin
　 　 Antibiotic; inhibits bacterial DNA synthesis
　 4067 YK 4-279
　 　 Inhibitor of RNA helicase A (RHA)
　 6602 1M7
　 　 Reagent for RNA SHAPE-MaP chemistry
　 5962 3-AP
　 　 Ribonucleotide reductase inhibitor; also an iron chelator
　 4099 Azathioprine
　 　 Purine analog; prodrug of 6-mercaptopurine (Cat. No. 4103)
　 3771 Azithromycin
　 　 Antibiotic; inhibits 50S ribosomal subunit formation and elongation at transpeptidation
　 3681 Bendamustine hydrochloride
　 　 Cytostatic agent; exhibits DNA alkylating and purine analog properties
　 5015 5-BrdU
　 　 Synthetic thymidine analog; used for cell proliferation assays
　 4091 Cyclophosphamide
　 　 Alkylating agent; chemotherapeutic
　 3357 Ellipticine
　 　 Antitumor and intercalating agent; inhibits DNA topoisomerase II
　 6782 Indisulam
　 　 Pre-mRNA splicing modulator; hCA XII inhibitor
　 5284 trans-ISRIB
　 　 Integrated stress response (ISR) inhibitor
　 5185 JTE 607 dihydrochloride
　 　 Active metabolite binds CPSF3; Pro-drug
　 7004 NAI
　 　 Reagent for RNA SHAPE-MaP experiments in vivo; cell permeable
　 7003 NAI-N3 
　 　 Reagent for RNA icSHAPE experiments in vivo
　 5761 RG 102240
　 　 Gene switch ligand for use in induceable gene expression systems
　 5810 RS 1
　 　 High affinity RAD51 activator; also CRISPR enhancer
　 4990 Stavudine
　 　 Nucleoside analog; antiviral
　 6586 Targapremir 210
　 　 Inhibits formation of miR-210
　 4460 Trifluorothymidine
　 　 Thymidylate synthase inhibitor; induces DNA fragmentation