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 제품안내  신경약학   Cell Biology

DNA/RNA/Protein Synthesis Inhibitors

DNA, RNA, Protein 합성과정에 관여하는 inhibitor 를 소개합니다.

TOCRIS
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  Cat. No. Product Name / Activity
  4215 4E1RCat
    Protein translation inhibitor; blocks eIF4F subunit interaction
  4800 4EGI-1
    Inhibitor of eIF4E:eIF4G interaction
  1229 Actinomycin D
    RNA polymerase inhibitor
  2513 Acyclovir
    Viral DNA polymerase inhibitor
  4025 α-Amanitin
    Inhibitor of RNA polymerase II
  1290 Anisomycin
    Protein synthesis inhibitor
  5736 Aphidicolin
    DNA polymerase α, δ and ε inhibitor
  6392 B02
    RAD51 recombinase inhibitor
  2981 BIBR 1532
    Selective telomerase inhibitor
  5417 BMH 21
    RNA polymerase 1 inhibitor; also p53 pathway activator
  5312 BRACO 19 trihydrochloride
    Telomerase inhibitor
  6196 Brequinar sodium
    Potent and selective DHODH inhibitor
  4799 Capecitabine
    Prodrug of 5-Fluorouracil (Cat. No. 3257). Inhibits DNA synthesis
  2626 Carboplatin
    Inhibitor of DNA synthesis
  4436 8-Chloroadenosine
    Cytotoxic nucleoside analog; inhibits RNA synthesis
  2294 Cordycepin
    RNA synthesis inhibitor
  2483 Costunolide
    Inhibitor of human telomerase activity
  970 Cycloheximide
    Inhibitor of protein synthesis
  4520 Cytarabine
    Nucleoside analog; inhibits DNA replication
  3917 Daptomycin
    Antibiotic; inhibits protein, DNA and RNA synthesis in gram-positive bacteria
  1467 Daunorubicin hydrochloride
    RNA synthesis inhibitor
  3857 Dexrazoxane hydrochloride
    Topoisomerase II inhibitor
  3260 Epirubicin hydrochloride
    Inhibits DNA synthesis and function. Inhibits DNA topoisomerase II
  4659 Floxuridine
    Disrupts DNA replication; inhibits thymidylate synthetase
  3495 Fludarabine
    Purine analog; inhibits DNA synthesis
  3257 5-Fluorouracil
    Inhibits RNA and DNA synthesis
  4131 G418 disulfate salt
    Aminoglycoside antibiotic; used in cell culture
  3259 Gemcitabine hydrochloride
    DNA synthesis inhibitor
  1993 Halofuginone hydrobromide
    High affinity competitive prolyl-tRNA synthetase inhibitor
  1416 Homoharringtonine
    Inhibitor of protein synthesis; antileukemic agent
  5740 6-Hydroxy-DL-DOPA
    Allosteric inhibitor of RAD52; also APE1 inhibitor
  6483 Isoginkgetin
    Pre-mRNA splicing inhibitor; cell permeable
  7338 K 22 
    Inhibits coronavirus RNA replication; impairs double membrane vesicle (DMV) formation
  6068 Lin28 1632
    RNA binding protein Lin28 inhibitor; promotes mESC differentiation; also bromodomain inhibitor
  3765 Linezolid
    Antibiotic; inhibits protein synthesis in gram-positive bacteria
  6510 LNT 1
    Potent flap endonuclease 1 (FEN1) inhibitor; induces DNA damage response
  6819 Mefloquine hydrochloride
    Binds 80S ribosome and inhibits protein synthesis in P falciparum; also gap junction blocker
  4103 6-Mercaptopurine
    Purine analog; inhibits DNA and RNA synthesis
  1489 Mithramycin A
    Inhibitor of DNA and RNA polymerase
  3258 Mitomycin C
    Inhibitor of DNA synthesis
  6359 Nelarabine
    Purine nuceloside analog; inhibits DNA synthesis
  5340 NSC 617145
    Werner syndrome helicase (WRN) inhibitor
  2623 Oxaliplatin
    Inhibitor of DNA synthesis
  5419 PCNA I1
    PCNA inhibitor
  6222 PFM 01
    MRE11 endonuclease inhibitor
  6070 Pladienolide B
    mRNA splicing inhibitor; antitumor
  4089 Puromycin dihydrochloride
    Protein synthesis inhibitor
  6168 RI 1
    RAD51 recombinase inhibitor
  4501 Ribavirin
    Antiviral guanosine analog; blocks eIF4E activity
  4121 Rifampicin
    Antibiotic; inhibits bacterial RNA polymerase
  4723 T2AA
    PCNA inhibitor
  6884 TC SL C5
    Metastasis-associated lung adenocarcinoma transcript 1 (Malat1) RNA inhibitor
  5069 Teriflunomide
    Inhibitor of DHODH; active metabolite of Leflunomide
  3267 Thiostrepton
    Antibiotic, inhibits protein synthesis
  4309 TPEN
    RNA binding protein Lin28 inhibitor; cell-permeable Zn2+ chelator
  3253 Triptolide
    Inhibits RNAPII-mediated transcription; antitumor, anti-inflammatory and immunosuppressive
  3863 Trovafloxacin mesylate
    Antibiotic; inhibits bacterial DNA synthesis
  3787 Viomycin
    Antibiotic; inhibits bacterial DNA synthesis
  4067 YK 4-279
    Inhibitor of RNA helicase A (RHA)
  6602 1M7
    Reagent for RNA SHAPE-MaP chemistry
  5962 3-AP
    Ribonucleotide reductase inhibitor; also an iron chelator
  4099 Azathioprine
    Purine analog; prodrug of 6-mercaptopurine (Cat. No. 4103)
  3771 Azithromycin
    Antibiotic; inhibits 50S ribosomal subunit formation and elongation at transpeptidation
  3681 Bendamustine hydrochloride
    Cytostatic agent; exhibits DNA alkylating and purine analog properties
  5015 5-BrdU
    Synthetic thymidine analog; used for cell proliferation assays
  4091 Cyclophosphamide
    Alkylating agent; chemotherapeutic
  3357 Ellipticine
    Antitumor and intercalating agent; inhibits DNA topoisomerase II
  6782 Indisulam
    Pre-mRNA splicing modulator; hCA XII inhibitor
  5284 trans-ISRIB
    Integrated stress response (ISR) inhibitor
  5185 JTE 607 dihydrochloride
    Active metabolite binds CPSF3; Pro-drug
  7004 NAI
    Reagent for RNA SHAPE-MaP experiments in vivo; cell permeable
  7003 NAI-N3 
    Reagent for RNA icSHAPE experiments in vivo
  5761 RG 102240
    Gene switch ligand for use in induceable gene expression systems
  5810 RS 1
    High affinity RAD51 activator; also CRISPR enhancer
  4990 Stavudine
    Nucleoside analog; antiviral
  6586 Targapremir 210
    Inhibits formation of miR-210
  4460 Trifluorothymidine
    Thymidylate synthase inhibitor; induces DNA fragmentation