Cannabinoid Receptor Small Molecules

Cannabinoid Receptor agonist & antagonist를 소개합니다.

TOCRIS

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	Agonists
	Cat. No.	Product Name / Activity
	1319	ACEA
		Potent and highly selective CB1 agonist
	1318	ACPA
		Potent and selective CB1 agonist
	1781	ACPA (in Tocrisolve™ 100)
		Potent and selective CB1 agonist; supplied in water-soluble emulsion
	1354	Arvanil
		Potent CB1 agonist; also anandamide transport inhibitor and TRPV1 agonist
	1485	DEA
		Endogenous CB1 agonist
	2139	Leelamine hydrochloride
		CB1 agonist
	1121	(R)-(+)-Methanandamide
		Potent and selective CB1 agonist
	1782	(R)-(+)-Methanandamide (in Tocrisolve™ 100)
		Potent and selective CB1 agonist; supplied in water-soluble emulsion
	1568	NADA
		Endogenous CB1 agonist; also vanilloid agonist and inhibitor of FAAH and AMT
	1411	Noladin ether
		Endogenous agonist for CB1 and GPR55
	0878	Oleamide
		CB1 agonist
	3744	RVD-Hpα
		Selective CB1 agonist; also CB2 PAM

	Inverse Agonists
	Cat. No.	Product Name / Activity
	1115	AM 281
		Potent and selective CB1 inverse agonist
	3791	Hemopressin (human, mouse)
		Selective CB1 inverse agonist
	1764	Hemopressin (rat)
		Selective CB1 inverse agonist
	2387	LY 320135
		Selective CB1 inverse agonist
	0923	SR 141716A
		Selective CB1 inverse agonist
	4345	TC-C 14G
		High affinity and potent CB1 inverse agonist

	Antagonists
	Cat. No.	Product Name / Activity
	1117	AM 251
		Potent CB1 antagonist; also GPR55 agonist
	6193	AM 4113
		High affinity and selective CB1 antagonist
	5443	AM 6545
		High affinity and selective CB1 antagonist
	6763	AVE 1625
		Potent and selective CB1 receptor antagonist
	4236	CP 945598 hydrochloride
		CB1 antagonist
	4063	MJ 15
		Potent and selective CB1 antagonist
	5746	NESS 0327
		Ultra-high affinity and selective CB1 antagonist
	3676	PF 514273
		High affinity and selective CB1 antagonist
	4605	(±)-SLV 319
		High affinity and selective CB1 antagonist

	Modulators
	Cat. No.	Product Name / Activity
	2957	Org 27569
		Potent allosteric modulator of CB1 receptors
	5321	PSNCBAM-1
		Negative allosteric modulator of CB1 receptors

	Others
	Cat. No.	Product Name / Activity
	1655	O-2050
		Putative CB1 antagonist; displays mixed activity at CB receptors
	2540	Tocrifluor T1117
		Fluorescent cannabinoid ligand; fluorescent form of AM 251 (Cat. No. 1117)

	Agonists
	Cat. No.	Product Name / Activity
	2663	CB 65
		High affinity, selective CB2 agonist
	2678	GP 2a
		Selective CB2 agonist
	2374	GW 405833
		Selective, high affinity CB2 receptor partial agonist
	3088	HU 308
		Potent and selective CB2 agonist
	1341	JWH 015
		Selective CB2 agonist
	1343	JWH 133
		Potent and selective CB2 agonist
	5826	LEI 101 hydrochloride
		Potent and selective CB2 partial agonist; orally biovailable
	4205	MDA 19
		CB2 agonist
	6220	PM 226
		Potent and selective CB2 receptor agonist; BBB permeable; neuroprotective
	3556	SER 601
		Potent, selective CB2 agonist

	Inverse Agonists
	Cat. No.	Product Name / Activity
	1120	AM 630
		Selective CB2 inverse agonist
	4756	COR 170
		Selective CB2 receptor inverse agonist
	2764	GP 1a
		CB2 receptor inverse agonist
	2479	JTE 907
		Selective CB2 receptor inverse agonist
	5815	SCH 336
		Highly potent and selective CB2 inverse agonist
	5039	SR 144528
		High affinity and selective CB2 inverse agonist

	Modulators
	Cat. No.	Product Name / Activity
	6832	Ec2la
		Positive allosteric modulator of CB2 receptors; active in vivo
	3744	RVD-Hpα
		High affinity CB2 positive allosteric modulator; also CB1 agonist

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