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 Á¦Ç°¾È³»  ºÐ¼® Á¦ÀÛ ¼­ºñ½º   ½Å¾à°³¹ß Ž»ö ¼­ºñ½º  CYP, Drug metabolism

xTAG¢ç CYP2D6 Kit v3

CYP2D6´Â Ç×Á¤½Åº´ ¾à, ÁøÅëÁ¦ ¹× ½ÉÇ÷°ü ¾à¹°À» Æ÷ÇÔÇÑ ¸¹Àº ¾à¹°ÀÇ ºÐÇØ¿¡ °ü¿©ÇÕ´Ï´Ù. CYP2D6ÀÇ À¯ÀüÀÚÇü ½Äº°Àº ÀÓ»óÀǰ¡ ÀûÀýÇÑ Ä¡·á¹ýÀ» ¼±ÅÃÇÏ¿© ¾à¹°Ä¡·á¸¦ °³º°È­ Çϴµ¥¿¡ µµ¿òÀ» ÁÙ ¼ö ÀÖ½À´Ï´Ù. xTAG CYP2D6 KitÀ» ÅëÇØ °³Ã¼°£ CYP2D6 genotypingÀ» ¼ö¿ùÇÏ°Ô ÁøÇàÇÒ ¼ö ÀÖ½À´Ï´Ù.

Luminex
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  • xTAG CYP2D6 KitÀº qualitative genotyping assay·Î, ´ë»ç ÀúÇÏ À¯ÀüÀÚÇüÀÇ ¿©ºÎ¸¦ ÆÄ¾ÇÇÔÀ¸·Î¼­, ÀÓ»óÀǰ¡ CYP2D6 À¯ÀüÀÚ¿¡ ÀÇÇØ ´ë»çµÇ´Â ¾à¹°ÀÇ Ä¡·á Àü·«À» °áÁ¤Çϴµ¥¿¡ µµ¿òÀ» ÁÙ ¼ö ÀÖ½À´Ï´Ù.
  • Deletion (*5)¿Í º¹Á¦À¯ÀüÀÚÇü °ü·Ã gene rearrangement¿Í °°Àº nucleotide variantsÀÇ ÆÐ³ÎÀ» °ËÃâÇÕ´Ï´Ù.
  • Multiplex PCR ¹ý°ú Luminex 200À» ÀÌ¿ëÇÑ Allele Specific Primer Extension (ASPE) ¹ýÀ¸·Î ºÐ¼®Çϸç, °¢ »ùÇÃÀÇ diplotypeÀ» °áÁ¤ÇØ ÁÝ´Ï´Ù.
  • Reliable : High quality in vitro diagnostic test with 100% accuracy and reproducibility
  • Actionable : Detect 17 different mutations/polymorphisms, including gene deletion and duplication
  • Efficient : Genotyping and streamlined protocol provides same day results

  • Genotypes (IVD Panel) : *1, *2, *3, *4, *5, *6, *7, *8, *9, *10, *11, *15, *17, *29, *35, *41
  • Instrument & Software : Luminex 100/200 instrument with xPONENT® software
  • Reproducibility : 100%
  • Kit Accuracy : 100% compared to Dideoxy Sequencing
  • Optimal Input DNA : 24 ng to 1800 ng
  • Sample Type : EDTA Blood & Citrate Blood






  • Primer Mixes
    - xTAG 2D6 v3 PCR Primer Mix A
    - xTAG 2D6 v3 PCR Primer Mix B
    - xTAG 2D6 v3 ASPE Primer Mix
  • Enzymes and Buffers
    - xTAG  Reporter Buffer
    - Platinum® Tfi Exo(-) DNA Polymerase
    - Platinum Tfi Reaction Buffer, 5x
    - Tfi 50 mM MgCl2
    - xTAG Exonuclease I
    - xTAG Shrimp Alkaline Phosphatase
    - xTAG Hot Start Taq (Long Acting)
    - xTAG 10x Taq Buffer (Long Acting)
  • Beads & Reporter
    - xTAG 2D6 v3 Bead Mix
    - xTAG Streptavidin
    - R-Phycoerythrin Conjugate

 

 



ÁÖ¹®Á¤º¸(Ordering Information)
CATNUM PRODUCT SIZE
I030B0451xTAG CYP2D6 Kit v3 (IVD)48 Tests